JP5394246B2 - 抗体及びイムノコンジュゲートとこれらの使用方法 - Google Patents
抗体及びイムノコンジュゲートとこれらの使用方法 Download PDFInfo
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- JP5394246B2 JP5394246B2 JP2009534901A JP2009534901A JP5394246B2 JP 5394246 B2 JP5394246 B2 JP 5394246B2 JP 2009534901 A JP2009534901 A JP 2009534901A JP 2009534901 A JP2009534901 A JP 2009534901A JP 5394246 B2 JP5394246 B2 JP 5394246B2
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| JPS5990947A (ja) * | 1982-11-16 | 1984-05-25 | Matsushita Electronics Corp | 半導体装置 |
| EP3409287B9 (en) * | 2010-09-29 | 2021-07-21 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 191p4d12 proteins |
| US8987209B2 (en) * | 2010-09-29 | 2015-03-24 | Seattle Genetics, Inc. | N-carboxyalkyl-auristatin and the use thereof |
| MX346500B (es) * | 2010-11-10 | 2017-03-22 | Genentech Inc * | Metodos y composiciones para inmunoterapia para enfermedad neural. |
| DK2694111T3 (en) * | 2011-04-01 | 2016-10-10 | Wyeth Llc | Antibody pharmaceutical conjugates |
| MY168297A (en) | 2011-11-17 | 2018-10-23 | Pfizer | Cytotoxic Peptides and Antibody Drug Conjugates Thereof |
| BR112014012882A2 (pt) * | 2011-11-29 | 2017-06-13 | Genentech Inc | método, anticorpo, polinucleotídeo, célula hospedeira, linhagem celular de hibridoma, uso do anticorpo e kit |
| EP2848686B1 (en) * | 2012-04-04 | 2024-12-25 | Perseus Proteomics Inc. | Conjugate of anti-cdh3 (p-cadherin) antibody and drug |
| CN112587671A (zh) * | 2012-07-18 | 2021-04-02 | 博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
| MX379256B (es) * | 2013-03-15 | 2025-03-10 | Regeneron Pharma | Moleculas biologicamente activas, conjugados de las mismas, y usos terapeuticos. |
| CN105899539B (zh) * | 2014-01-10 | 2021-11-09 | 博笛生物科技有限公司 | 用于免疫疗法的化合物和组合物 |
| US20170043034A1 (en) * | 2014-01-24 | 2017-02-16 | Genentech, Inc. | Methods of using anti-steap1 antibodies and immunoconjugates |
| TWI731535B (zh) * | 2014-03-21 | 2021-06-21 | 美商艾伯維有限公司 | 抗-egfr抗體及抗體藥物結合物 |
| CN106536540A (zh) | 2014-07-24 | 2017-03-22 | 基因泰克公司 | 将试剂缀合至含有至少一个三硫键的蛋白质中的巯基部分的方法 |
| WO2017055388A2 (en) * | 2015-10-02 | 2017-04-06 | F. Hoffmann-La Roche Ag | Bispecific t cell activating antigen binding molecules |
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| WO2021148500A1 (en) * | 2020-01-22 | 2021-07-29 | Medimmune Limited | Compounds and conjugates thereof |
| CN111494645B (zh) * | 2020-05-20 | 2022-09-30 | 中国药科大学 | 抗人dll4人源化抗体与美登素生物碱dm1的偶联物及其制备方法与应用 |
| IL308508A (en) * | 2021-05-24 | 2024-01-01 | Remegen Co Ltd | Use of a HER2-targeted antibody-drug conjugate for the treatment of low-HER2-expressing breast cancer |
| JP7451677B2 (ja) * | 2021-07-19 | 2024-03-18 | 煙台邁百瑞国際生物医薬股▲ふん▼有限公司 | 二成分毒素を担った抗体薬物複合体及びその応用 |
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| DK1244705T3 (da) * | 1999-12-06 | 2010-05-31 | Agensys Inc | Serpentintransmembrane antigener udtryk i human prostatacancere og anvendelser deraf |
| ES2443996T3 (es) * | 2004-04-22 | 2014-02-21 | Agensys, Inc. | Anticuerpos y moléculas derivadas de los mismos que se unen a proteínas STEAP-1 |
| KR101270829B1 (ko) * | 2004-09-23 | 2013-06-07 | 제넨테크, 인크. | 시스테인 유전자조작 항체 및 접합체 |
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| JP2014042522A (ja) | 2014-03-13 |
| JP5837019B2 (ja) | 2015-12-24 |
| JP2016063817A (ja) | 2016-04-28 |
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