JP5329729B2 - 脈管形成に有効な単位用量のｆｇｆ−２および使用方法 - Google Patents
脈管形成に有効な単位用量のｆｇｆ−２および使用方法 Download PDFInfo
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
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| US10410298P | 1998-10-13 | 1998-10-13 | |
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| PCT/US1999/019770 WO2000013701A2 (en) | 1998-09-03 | 1999-08-27 | Angiogenically effective unit dose of fgf-2 and method of use |
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| US8618052B2 (en) | 1998-10-13 | 2013-12-31 | Novartis Vaccines And Diagnostics, Inc. | Method of treating coronary artery disease by administering FGF-5 |
| US20020072489A1 (en) * | 1998-10-13 | 2002-06-13 | Whitehouse Martha J. | Angiogenically effective unit dose of FGF-2 and method of use |
| JP2002527401A (ja) | 1998-10-13 | 2002-08-27 | カイロン コーポレイション | Ｆｇｆの脈管形成的に有効な単位用量および投与方法 |
| JP5704780B2 (ja) * | 1999-08-13 | 2015-04-22 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | 脈管形成因子の用量および心筋血流を改善するための投与方法 |
| US20020032153A1 (en) * | 2000-03-10 | 2002-03-14 | Whitehouse Martha Jo | Methods and compositions for the treatment and prevention of erectile dysfunction |
| EP1894570A3 (en) * | 2000-06-22 | 2009-11-11 | Novartis Vaccines and Diagnostics, Inc. | Methods and compositions for the treatment of peripheral artery disease |
| US20020115603A1 (en) | 2000-06-22 | 2002-08-22 | Chiron Corporation | Methods and compositions for the treatment of peripheral artery disease |
| KR101413844B1 (ko) | 2008-12-09 | 2014-06-30 | 화이자 백신스 엘엘씨 | ＩｇＥ ＣＨ３ 펩티드 백신 |
| WO2018200040A1 (en) * | 2017-04-26 | 2018-11-01 | University Of Cincinnati | Compositions of fibroblast growth factor ligands and methods of treating patients unergoing ischemia-reperfusion therapy |
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| US4959314A (en) | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
| US5439818A (en) | 1985-09-12 | 1995-08-08 | Scios Nova Inc. | DNA encoding human recombinant basic fibroblast growth factor |
| ATE105868T1 (de) * | 1985-09-12 | 1994-06-15 | Scios Nova Inc | Rekombinanter fibroblast-wachstumsfaktor. |
| US5852177A (en) * | 1987-02-24 | 1998-12-22 | Takeda Chemical Industries, Ltd. | Basic fibroblast growth factor (bFGF) muteins |
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| JP2002524420A (ja) | 2002-08-06 |
| DE69941034D1 (de) | 2009-08-06 |
| AU6022399A (en) | 2000-03-27 |
| ES2233101T3 (es) | 2005-06-01 |
| EP2123292A1 (en) | 2009-11-25 |
| EP2123292B1 (en) | 2016-05-04 |
| DE69921348D1 (de) | 2004-11-25 |
| ATE279937T1 (de) | 2004-11-15 |
| WO2000013701A3 (en) | 2000-08-03 |
| WO2000013701A2 (en) | 2000-03-16 |
| JP2010163457A (ja) | 2010-07-29 |
| EP1121142A2 (en) | 2001-08-08 |
| EP1121142B1 (en) | 2004-10-20 |
| ATE434440T1 (de) | 2009-07-15 |
| WO2000013701A9 (en) | 2000-10-05 |
| HK1075409A1 (en) | 2005-12-16 |
| DE69921348T2 (de) | 2006-02-09 |
| ES2327839T3 (es) | 2009-11-04 |
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