JP5306160B2 - Use of a specific fragrance component for producing a fragrance composition for mental sedation, and a method for imparting a mental sedative effect in the fragrance composition - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To find out a new component acknowledged to have mental sedation effect and to prepare a perfume composition for mental sedation containing the new component. <P>SOLUTION: It is found that terpinel butyrate, &gamma;-nonalactone, acetyl isoeugenol, methyl anisate, terpineol, nerol, crysanthenone, lillal, lillial, &beta;-phenylethyl alcohol, &gamma;-methyl ionone, iso E Super, Z-3-hexenyl salicylate, p-methylphenyl acetaldehyde, limonene, ocimene, helional, linallyl acetate, geranyl acetate, geraniol, hedion, linalol, citronellol and &gamma;-hexalactone are acknowledged to have mental sedation effect, thereby the perfume composition containing such components can be provided. <P>COPYRIGHT: (C)2010,JPO&amp;INPIT

Description

The present invention relates to a fragrance composition having a specific psychological action, and more specifically, the use of a fragrance ingredient for producing a sedation fragrance composition having a sedative action. And a method for imparting a mental sedative effect in a fragrance composition .

  It has been clarified that various effects are observed physiologically and psychologically by various stresses. In particular, in modern society, which is also called a stress society, how to deal with various types of stress is a very important issue.

  The provision of mental healing can be cited as a means of reducing the adverse mental effects of stress on humans. As a typical aspect of this healing, it is possible to sedate a spirit that tends to be irritated by various stresses.

In recent years, especially aromatherapy has attracted attention as a means of calming the mind. Traditionally, it has been traditionally confirmed that lavender oil, camomil oil, etc. have a sedative effect on the spirit in aromatherapy , and these can exert a sedative effect by aroma, so the desired sedation is very mild. It has the advantage that an effect can be acquired.

  However, selection and blending of natural fragrances that should exert a mental sedative effect are largely based on empirical judgments by experts in aromatherapy, and the effects are not necessarily clear. This is considered to be largely attributable to the fact that natural fragrances such as essential oils used for aromatherapy are composed of various components.

  Therefore, for example, in JP-A-6-172781, 1,3-dimethoxy-5-methylbenzene has a sedative effect, and the effect is also exhibited by adding this to a fragrance and evaporating and sucking it. Furthermore, since the fragrance of the compound itself is not strong, it has been reported that this compound can be added to various fragrances to exert a mental sedative effect.

However, in order to actually obtain a mental sedative effect in various life situations and aromatherapy , it depends on the preference for the fragrance of many people and the compatibility with various fragrances used according to the life situation. It is necessary to be able to easily create an appropriate prescription. For that purpose, it is necessary to find a substance that can exert more various mental sedative effects.

  Therefore, the problem to be solved by the present invention is to find a new ingredient that has a mental sedative effect and to create a sedative fragrance composition containing the same.

In order to solve this problem, the present inventor has examined the sedative effect of many components. As a result, among the components contained in natural essential oils, terpinyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, chrysanthenone, laral, lyial, γ-methylionone, iso-e super, Z-3-hexenyl Salicylate, p-methylphenylacetaldehyde (also referred to as syringaldehyde), osymene, helional, linalyl acetate, geranyl acetate, hedione, citronellol, and γ-hexalactone have a mental sedative effect (hereinafter also referred to as a mental sedative effect). And the present invention relating to a sedative fragrance composition was completed.

That is, the present invention relates to terpinyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, chrysantenone, lyral, lyial, γ-methylionone, iso-e-super, for producing a sedative fragrance composition. Use of one or more components selected from the group consisting of Z-3-hexenylsalicylate, p-methylphenylacetaldehyde, osmene, helional, linalyl acetate, geranyl acetate, hedion, citronellol, and γ-hexalactone, It is the invention which provides.
Furthermore, the present invention provides a perfume composition comprising terpinyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, chrysantenone, laral, lyial, γ-methylionone, iso-e super, Z-3-hexenyl salicylate. Perfume composition by blending one or two or more components selected from the group consisting of p-methylphenylacetaldehyde, osmene, helional, linalyl acetate, geranyl acetate, hedion, citronellol, and γ-hexalactone It is also an invention that provides a method of imparting a mental sedation effect to a product.

  In this invention, the fragrance composition for mental sedation means the fragrance composition which exhibits the effect which makes a user mentally sedate and gives a relaxation feeling by using this. The fragrance composition for mental sedation contains this in external compositions such as cosmetics, deodorants for rooms, aromas such as aroma candles, food compositions, etc. Can be granted. The sedative effect means, for example, the effect that humans experience in daily life, liberate from physiological psychological states such as irritation and excitement, and relax their feelings. It is possible to confirm with an index (for example, CNV measurement or the like) that can detect a typical sedation.

According to the present invention, a new ingredient having a mental sedative effect is found, and based on this, a fragrance composition for mental sedation, and an external composition and miscellaneous goods containing the fragrance composition are provided. The

It is drawing which shows the CNV measurement result about the component of the composition for this mental sedation.

Embodiments of the present invention will be described below.
Terpinyl butyrate, that is, Terpinyl butyrate, which is a component of the present sedative composition, is known as a fragrance having a rosemary-like balsamic and floral fragrance. Terpinyl butyrate can be produced by a conventional method and used in the present invention, and a commercially available product can also be used.

  [gamma] -nonalactone, i.e., [gamma] -Nonalacton, is known as a perfume having a creamy coconut flavor. γ-Nonalactone can be isolated and purified from essential oils such as peach by a conventional method and used in the present invention, and a commercially available product can also be used.

  Acetyl isoeugenol, or Methoxy-4-acetopropylenebenzene, is known as a perfume with a sweet floral aroma like perilla and balsamic, carnation. Acetylisoeugenol can be produced by a conventional method and used in the present invention, and a commercially available product can also be used.

  Methyl anisate, ie, methyl anisate, is known as a fragrance having a sweet herbal and anise fragrance reminiscent of lilac and magnolia. Methyl anisate can be produced by a conventional method and used in the present invention, and a commercially available product can also be used.

  Chrysanthenone, or Chrysanthenone, is known as a fragrance with a metallic herbal green fragrance. Chrysantenone can be used in the present invention after being isolated and purified from an essential oil such as Artemisia by a conventional method, and a commercially available product can also be used.

  Lyral, or Lyral, is known as a perfume having a lily of the valley scent. Liral can be produced by a conventional method and used in the present invention, and a commercial product can also be used.

  Lilyal, or Lilia, is known as a perfume with a lily of the valley scent. Liliaal can be produced by a conventional method and used in the present invention, and a commercially available product can also be used.

  γ-methylionone, that is, γ-methyl ionone, is known as a fragrance having a mild violet-like or Oris-like odor. γ-Methylionone can be produced by a conventional method and used in the present invention, and a commercially available product can also be used.

  Iso E Super, or Iso E Super, is known as a fragrance with a woody amber-like fragrance. IsoE super can be produced by a conventional method and used in the present invention, and a commercially available product can also be used.

  Z-3-hexenyl salicylate, or cis-3-hexenyl salicylate, is known as a fragrance having a balsamic floral-like fragrance. Z-3-hexenyl salicylate can be produced by a conventional method and used in the present invention, and a commercially available product can also be used.

  p-methylphenylacetaldehyde, i.e., p-methylphenylacetaldehyde is known as a fragrance having a fruity and green fragrance. For example, p-methylphenylacetaldehyde can be isolated and purified by an ordinary method from essential oils such as corn and used in the present invention, and a commercially available product can also be used.

  Ocicle, or Ocimene, is known as a fragrance with a green, woody, and herbal fragrance that recalls anise and citrus lime. Ocymen can be isolated and purified from essential oils such as thyme by a conventional method and used in the present invention, and commercially available products can also be used.

  Helional, or Helional, is known as a fragrance with a sweet heliotrope, anise-like floral aroma. Helional can be produced by a conventional method and used in the present invention, and a commercially available product can also be used.

  Linalyl acetate, or Linallyl acetate, is known as a fragrance with a fresh and sweet fruity floral fragrance. For example, linalyl acetate can be isolated and purified from an essential oil such as lavender by a conventional method and used in the present invention, and a commercially available product can also be used.

  Geranyl acetate, or Geranyl acetate, is known as a fragrance having a sweet rose-like fragrance. For example, geranyl acetate can be isolated and purified from an essential oil such as lemon by a conventional method and used in the present invention, and a commercially available product can also be used.

  Headion, or Hedione, is known as a fragrance with a jasmine floral aroma. The headion can be isolated and purified from an essential oil such as jasmine by a conventional method and used in the present invention, and a commercially available product can also be used.

  Citronellol, or Citronellol, is known as a fragrance with a fresh rose-like aroma. Citronellol can be isolated and purified from essential oils such as rose by a conventional method and used in the present invention, and a commercially available product can also be used.

  γ-Hexalactone, ie, γ-Hexalactone, is known as a fragrance having a warm herbal, tobacco, and coumarin-like fragrance. γ-hexalactone can be isolated and purified from an essential oil such as apricot by a conventional method and used in the present invention, and a commercially available product can also be used.

  This mental sedation composition is an essential component, terpinyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, nerol, chrysanthenone, laral, lyial, β-phenylethyl alcohol, γ-methylionone, Selected from the group consisting of iso-e-super, Z-3-hexenyl salicylate, p-methylphenylacetaldehyde, limonene, osimene, helional, linalyl acetate, geranyl acetate, geraniol, hedion, linalool, citronellol, and γ-hexalactone It may be a fragrance composition comprising one or two or more components themselves, and other fragrance components, essential oils, etc. may have a desired sedative effect to improve scent preference. Naju effect Within limits which are not offset by the masking effect, etc., as appropriate, it may be contained. This mental sedation composition can be mainly used as a blended fragrance. The mental sedation composition can also contain general components that can generally be contained in a fragrance composition, such as antioxidants, preservatives, chelating agents, ultraviolet absorbers, dyes, and the like. .

  This mental sedation composition can be mainly contained as a blended fragrance in an object capable of containing a fragrance to exert a sedative effect.

  Examples of such objects include, but are not limited to, compositions for external use such as cosmetics, deodorants for rooms, fragrances such as aromatics and aroma candles, food compositions, and the like.

  The content of the mental sedation composition in these objects can be freely selected according to the type of the object and the type of fragrance to be selected, within the limit that the mental sedation effect can be exhibited. In general, it can be selected according to the general content of the blended fragrance. Generally, it is preferable that it is 0.01-50.0 mass% with respect to a target object, and it is especially suitable that it is 0.1-20.0 mass%. In many cases, 10.0% by mass is extremely suitable.

When the composition for mental sedation is contained in an object, it contains components having a sedative effect ( terpinyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, chrysantenone, laral, lyial, γ-methylionone, iso 1 type or 2 or more types selected from the group consisting of e-super, Z-3-hexenyl salicylate, p-methylphenylacetaldehyde, osmene, helional, linalyl acetate, geranyl acetate, hedion, citronellol, and γ-hexalactone ) It is generally preferable that the total amount is 0.001 to 50.0% by mass with respect to the object, and that 0.01 to 20.0% by mass is the same considering the palatability. Is particularly preferable, and is 1.0 to 10.0% by mass. It is often very suitable. When the content of the component is less than 0.001% by mass with respect to the object, even if the influence of other compounding components is minimized, there is a tendency that sufficient mental sedation effect is not exhibited, and 50.0% by mass. Even if blended in excess of%, an improvement in the mental sedation effect commensurate with the content of the component having a mental sedative effect is not recognized, and there is a tendency that the balance of the fragrance is generally unfavorable.

  In addition to the mental sedation composition, the general constitutive elements corresponding to the type of the target object within the range that does not lose the intended effect of the present invention include the mental sedation composition. Used.

  For example, when the object is a composition for external use such as cosmetics, the specific dosage form (liquid, powder, granule, aerosol, solid, gel, etc.) or product form of the composition for external use Accordingly, general components contained in these external compositions can be contained in addition to the mental sedative composition.

  Examples of cosmetics that are one of the most preferred embodiments of the composition for external use include, for example, perfume, eau de toilette, eau de cologne, cream / milky lotion, lotion, foundations, powdered white powder, lipstick, pomade, soap, shampoo. -Rinses, body shampoos, body rinses, body powders, bath agents, etc. are exemplified as specific product forms.

  Moreover, as daily miscellaneous goods, room fragrances, deodorants, aroma candles and the like are exemplified as specific product forms.

  In addition, this invention is also invention which provides the mental sedation method which sedates a mind by making this composition for mental sedation aspirate.

  The subject to which the present composition for sedation is inhaled is usually a human being, but may be a mammal such as a dog or a cat. Moreover, the means to suck | inhale is normally performed via the target object (external composition, miscellaneous goods, food composition, etc.) containing this composition for mental relaxation. That is, a normal usage mode of these objects, or a specified usage mode (for example, use of an external composition such as cosmetics in an outer skin, ignition of an aroma candle as a miscellaneous product, fragrance or deodorant The inhalation target inhales the mental sedation composition contained in the subject according to the installation and spraying in the room, the food composition, etc. Subject's spirit is sedated.

  Hereinafter, the present invention will be described more specifically with reference to examples. In addition, the compounding quantity represented by% is the mass% with respect to the compounding object.

The mental sedation effect was examined by measuring a change in negative potential called CNV: Contingent Negative Variation (CNV). CNV is known as a slow potential fluctuation in the brain that is linked to a psychological process such as attention, expectation and expectation, and fluctuations in the level of consciousness.

  In order to search for a sample having a mental sedation effect, a light signal indicating the start of movement follows 2 seconds after the warning stimulus sound, and the panel is required to perform a button-pressed movement reaction at the same time as recognizing the light. Perform the test. In this series of repetitions, the sample is placed on the nose of the panel (about 10 cm ahead), and the panel can recognize the scent of the sample as it breathes. An electrode for CNV measurement is mounted on the frontal head of the panel, and a potential recording between the earlobe is measured. It has been reported that when a human is given caffeine exhibiting a wakefulness effect, the amplitude of CNV increases, and when nitrozepam exhibiting a sedative effect is inhaled, the amplitude of CNV decreases.

  The fluctuation of the CNV amplitude appears remarkably in the initial component of 400 to 1000 msec after the sound stimulation. Therefore, the variation area of the CNV amplitude in this section was expressed as a percentage (%) compared with the blank (in the case of odorless stimulation) as 100%, and this was used as an index for the mental sedation effect. When the area variation is 100% or less, the sedative effect is recognized, and when it is 100% or more, the awakening effect is recognized.

As test example samples, terpinyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, nerol, chrysanthenone, rilal, β-phenylethyl alcohol, γ-methylionone, iso-e-super, Z-3- 1% ethanol solution of hexenyl salicylate, p-methylphenylacetaldehyde, limonene, osymene, helional, linalyl acetate, geranyl acetate, geraniol, hedion, linalool, citronellol (each using a commercially available product), In Japanese Patent Laid-Open No. 6-172781, etc., 3-dimethoxy-5-methylbenzene (hereinafter also referred to as DMMB), which has been reported to have a sedative effect, and a remo that has been traditionally recognized as a mentally stimulating effect. Oil was prepared with 1% ethanol solution of (each was a commercially available product), the panel as healthy five adult women and in the above manner was subjected to CNV test.

  The results are shown in FIG. According to FIG. 1, terpinyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, nerol, chrysantenone, rilal, β-phenylethyl alcohol, γ-methylionone, iso-e-super, Z-3- Hexenyl salicylate, p-methylphenylacetaldehyde, limonene, osymene, helional, linalyl acetate, geranyl acetate, geraniol, hedion, linalool, citronellol, and γ-hexalactone may have a sedative effect similar to DMMB. It became clear (a spirit-enhancing effect was confirmed in lemon oil).

  Below, the specific prescription example of the composition for this sedation is shown as an Example below. The mental sedative effects of Examples 1 to 9 were confirmed by the CNV test described above.

[Example 1] Fragrance composition for sedation
Compounding component amount (parts by mass)
γ-Nonalactone 0.2
Methyl anisate 2.0
p-Methylphenylacedealdehyde 2.0
Ocimene (1%) 0.5
γ-Hexalactone 1.0
Bergamot oil 10.0
Methyl dihydro jasmonate (Hedione) 20.0
Linalool 28.0
Orange oil 1.0
Linaroll oxide 5.0
Phenylethyl alcohol 5.0
Benzyl alcohol 1.0
Benzaldehyde 4.5
Indol (10%) 0.5
Abs. Casesis 2.0
Nerol 2.0
Abs. Jasmin 1.0
Iso E Super 5.0
Galaxolide (50%) 10.0
Bacdanol 1.0
Anis alcohol 1.0
DPG 0.8

[Example 2] Fragrance composition for sedation
Compounding component amount (parts by mass)
Terpinyl butyrate 1.0
γ-Nonalactone 0.1
Ocimen (1%) 0.5
Methyl dihydro jasmonate (Hedione) 20.0
Vertofix coeur 15.0
Polysantol 10.0
Galaxolide (50%) 10.0
Bergamot oil 9.0
Orange oil 4.0
Ethyllinalool 3.0
Lilyal 2.0
Bacdanol 1.0
Linaroll 1.0
Coumarin 1.0
Ambroxane 1.0
Citronellol 1.0
β-Phenylethyl alcohol 1.0
Carone (1%) 1.0
Pine oil 1.0
Benzyl acetate 0.5
Stemone 0.5
Terpineol 2.0
Damascone alpha (10%) 0.3
Allylamyl glycolate 0.2
Everyl 0.2
Tripal 0.2
DPG 13.5

[Example 3] Fragrance composition for sedation
Compounding component amount (parts by mass)
Terpinyl butyrate 1.0
γ-Nonalactone 0.2
Methyl anisate 1.0
Chrysantenone 0.5
p-Methylphenylacedealdehyde 2.0
Hexalactone gangma 1.0
Methyl dihydro jasumonate (Hedion) 15.0
Lyral 13.0
Iso E super 12.0
Galaxolide (50%) 10.0
Orange oil 5.0
Linalool 15.0
γ-Methyl ionone 5.0
Limonene 10.0
cis-3-Hexenyl salicylate 2.0
β-Naphthylmethyl ether 1.0
Santalex 1.0
Mandarine oil 1.0
Rose oil 0.5
Laurel leaf oil 0.5
lyamyl glycolate 0.3
Damacene 0.2
DPG 2.8

Example 4 Fragrance composition for sedation
Compounding component amount (parts by mass)
Terpinyl butyrate 1.0
γ-Nonalactone 0.2
Methyl anisate 1.0
p-Methylphenylacedealdehyde 2.0
γ-Hexalactone 0.5
β-Phenylethyl alcohol 10.0
Limonene 10.0
Methyl dihydro jasmonate (Hedione) 10.0
Lyral 10.0
β-Ione 7.0
Geranyl acetate 1.0
Citronellol 7.0
Geraniol 2.0
Bergamot oil 5.0
Linalool 5.0
Hexyl salicylate 5.0
Galaxolide (50%) 5.0
cis-3-Hexenyl salicylate 5.0
Benzyl acetate 5.0
Lime oil 3.0
Mandarin oil 2.0
Rose oil 2.0
Abs. Jasmin 0.5
cis-3-Hexenol 0.2
DPG 0.6

[Example 5] Fragrance composition for sedation
Compounding component amount (parts by mass)
Acetyl iso Eugenol 2.0
Bacdanol 2.5
Bergamot oil 5.0
Grapefruit oil 4.0
Linalool 3.0
Linearyl acetate 3.0
Cedramber 1.5
Coumarin 1.0
Methyl dihydro jasmonate (Hedione) 30.0
Ambroxane 0.5
Cardamon oil 0.5
Geranium oil 0.5
Limonene 3.0
Allyl amyl glycate 0.1
Helional 1.0
Damascenene (10%) 0.2
Casesis base 345B 1.0
Benzyl acetate 1.0
Iso E super 20.0
Habanolide 8.0
Musk T 5.0
Ethyl linalool 5.0
Lavandin oil 2.0
DPG 0.2

[Example 6] Fragrance composition for sedation
Compounding component amount (parts by mass)
Acetyl iso Eugenol 1.0
Methyl dihydro jasmonate (Hedione) 20.0
Iso E super 15.0
Bergamot oil 10.0
DPG 5.2
Linearyl acetate 5.0
Habanolide 5.0
Dihydro myrcenol 5.0
Vertofix coeur 5.0
Bacanolol 3.0
Linalool 3.0
Musk T 3.0
Lavandin oil 3.0
Lyral 3.0
Coumarin 2.0
Limonene 2.0
Patchouli oil 2.0
Citronell 2.0
β-Phenylethyl alcohol 2.0
Vetiver oil 1.0
Ambroxane 0.5
Damascenene (10%) 0.5
Benzyl acetate 0.5
Everyl 0.5
Eugenol 0.2
Jasmin oil 0.2
Vanillin 0.1
Cinamon bark oil 0.1
Galbanum oil 0.1
Allylcyclohexyl propionate 0.1

Example 7 Fragrance composition for sedation
Compounding component amount (parts by mass)
Acetyl iso Eugenol 5.0
Methyl dihydro jasmonate (Hedione) 15.0
Lyral 13.0
Iso E super 12.0
Galaxolide (50%) 10.0
Orange oil 5.0
Linalool 20.0
γ-Methyl ionone 5.0
Limonene 5.0
cis-3-Hexenyl salicylate 2.0
β-Naphthylmethyl ether 1.0
Santalex 1.0
Mandarine oil 1.0
Rose oil 0.5
Laurel leaf oil 0.5
Allylamyl glycolate 0.3
Damascenene (10%) 0.2
DPG 3.5

[Example 8] Fragrance composition for sedation
Compounding component amount (parts by mass)
Acetyl iso Eugenol 2.0
β-Phenylethyl alcohol 12.0
Limonene 10.0
Methyl dihydro jasmonate (Hedione) 10.0
Lyral 10.0
β-Ione 7.0
Citronellol 7.0
Geraniol 3.0
Bergamot oil 5.0
Linalool 5.0
cis-3-Hexenyl salicylate 5.0
Benzyl acetate 5.0
Lime oil 3.0
Mandarine oil 2.0
Rose oil 2.0
Abs. Jasmin 0.5
cis-3-Hexenol 0.2
DPG 1.3

[Example 9] Fragrance composition for sedation
Compounding component amount (parts by mass)
Limonene 8.0
Linaroll 10.0
Linearyl acetate 5.0
Bergamot oil 5.0
Liffarome 0.05
Benzyl acetate 5.0
β-Phenylethyl alcohol 8.0
Liial 5.0
Lyral 3.0
β-ionone 0.5
Methyl dihydro jasmonate (Hedione) 15.0
α-Hexyl cinnamic aldrhydre 10.0
p-Methylphenylacedealdehyde 2.0
Helional 0.5
Aldehyde C-14 0.1
Iso E Super 5.0
Galaxolide (50%) 10.0
Ethylene brassylate 3.0
Benzyl benzoate 4.85

  Below, the formulation example of the typical product form of the composition for external use containing this sedative composition or miscellaneous goods is shown as an Example below. The compositions for external use or miscellaneous goods of these examples were found to have a sedative effect by a sensory test in a typical usage mode of each product form.

[Example 10] Bath agent
Compounding component amount (parts by mass)
Sodium bicarbonate 70.0
Anhydrous sodium sulfate 28.8
Fragrance composition for sedation of Example 3 1.0
Dye Y-202-1 0.2
<Production method>
The ingredients except the sedative fragrance composition were stirred with a V-type mixer until uniform, then the composition was added, and the mixture was further stirred until it became more uniform to obtain a bath preparation.

[Example 11] Gel air freshener
Compounding component amount (parts by mass)
Carrageenan 3.0
Propylene glycol 2.0
Propylparaben 0.3
Fragrance composition for sedation of Example 3 5.0
Ion exchange water 89.7
<Production method>
Carrageenan, propylene glycol and propylparaben were mixed and ion-exchanged water was added with stirring, and this was heated to about 80 ° C. with gentle stirring. Thereafter, the temperature is set to about 65 ° C., and the fragrance composition for mental sedation is added to a uniform phase while stirring at 3000 rpm using a homogenizer. It was.

[Example 12] Liquid type air freshener
Compounding component amount (parts by mass)
95% ethanol 25.0
Surfactant 5.0
Fragrance composition for sedation of Example 3 3.0
Ion exchange water 67.0
<Production method>
Each component except ion-exchanged water was mixed, and ion-exchanged water was added while stirring gently to obtain a liquid fragrance. In addition, polyoxyethylene nonyl phenyl ether EO-13 was used as the surfactant.

[Example 13] Liquid type deodorant
Compounding component amount (parts by mass)
Deodorant concentrate FS-500M (Shirai Matsushin Pharmaceutical Co., Ltd.) 5.0
95% ethanol 10.0
Surfactant 10.0
Perfume composition for mental sedation of Example 2 10.0
Ion exchange water 65.0
<Production method>
Components other than ion-exchanged water were mixed, and ion-exchanged water was added with gentle stirring to obtain a deodorant (liquid type). In addition, polyoxyethylene nonylphenyl ether EO-10 was used as the surfactant.

Example 14 Aerosol type deodorant
Compounding component amount (parts by mass)
Deodorant concentrate FS-500M 5.0
95% ethanol 20.0
Perfume composition for mental sedation of Example 2 10.0
Ion exchange water 40.0
Liquefied petroleum gas (4Kg / cm ² · 20 ° C) 25.0
<Production method>
Components other than liquefied petroleum gas were mixed and stirred to be uniform, a predetermined amount was placed in an aerosol container and a valve was attached, and then liquefied petroleum gas was injected to obtain a deodorant (aerosol type).

[Example 15] Bath agent
Compounding component amount (parts by mass)
Sodium bicarbonate 70.0
Anhydrous sodium sulfate 28.8
Fragrance composition for sedation of Example 7 1.0
Dye Y-202-1 0.2
<Production method>
The components excluding the sedative fragrance composition were stirred with a V-type mixer until uniform, and then the fragrance composition was added and stirred sufficiently until uniform to obtain a bath preparation.

Example 16 Gel Air Freshener
Compounding component amount (parts by mass)
Carrageenan 3.0
Propylene glycol 2.0
Propylparaben 0.3
Fragrance composition for sedation of Example 7 5.0
Ion exchange water 89.7
<Production method>
Carrageenan, propylene glycol and propylparaben were mixed and ion-exchanged water was added with stirring, and this was heated to about 80 ° C. with gentle stirring. Thereafter, the temperature is set to about 65 ° C., and the fragrance composition for mental sedation is added to a uniform phase while stirring at 3000 rpm using a homogenizer. It was.

[Example 17] Liquid type air freshener
Compounding component amount (parts by mass)
95% ethanol 25.0
Surfactant 5.0
Perfume composition for mental sedation of Example 3.0 3.0
Ion exchange water 67.0
<Production method>
Each component except ion-exchanged water was mixed, and ion-exchanged water was added while stirring gently to obtain a liquid fragrance. In addition, polyoxyethylene nonyl phenyl ether EO-13 was used as the surfactant.

[Example 18] Liquid type deodorant
Compounding component amount (parts by mass)
Deodorant concentrate FS-500M (Shirai Matsushin Pharmaceutical Co., Ltd.) 5.0
95% ethanol 10.0
Surfactant 10.0
Acetylisoeugenol 10.0
Ion exchange water 65.0
<Production method>
Components other than ion-exchanged water were mixed, and ion-exchanged water was added with gentle stirring to obtain a deodorant (liquid type). In addition, polyoxyethylene nonylphenyl ether EO-10 was used as the surfactant.

[Example 19] Aerosol type deodorant
Compounding component amount (parts by mass)
Deodorant concentrate FS-500M 5.0
95% ethanol 20.0
Acetylisoeugenol 10.0
Ion exchange water 40.0
Liquefied petroleum gas (4Kg / cm ² · 20 ° C) 25.0
<Production method>
Components other than liquefied petroleum gas were mixed and stirred to be uniform, a predetermined amount was placed in an aerosol container and a valve was attached, and then liquefied petroleum gas was injected to obtain a deodorant (aerosol type).

[Example 20] Cream
Compounding component amount (% by mass)
Stearic acid 10.0
Stearyl alcohol 4.0
Butyl stearate 8.0
Stearic acid monoglycerin ester 2.0
Vitamin E acetate 0.5
Vitamin A palmitate 0.1
Macadamia nut oil 1.0
Tea oil 3.0
Glycerin 4.0
1,2-pentanediol 3.0
Sodium hyaluronate 1.0
Potassium hydroxide 2.0
Magnesium ascorbate phosphate 0.1
L-arginine hydrochloride 0.01
Edetate trisodium 0.05
Fragrance composition for sedation of Example 9 0.4
Preservative Appropriate amount of purified water Residue <Production>
A cream was obtained by a conventional method.

[Example 21] Cream
Compounding component amount (% by mass)
Cetanol 4.0
Vaseline 7.0
Isopropyl myristate 8.0
Squalane 15.0
Stearic acid monoglycerol ester 2.2
POE (20) sorbitan monostearate 2.8
Vitamin E Nicotinate 2.0
Glycerin 10.0
Sodium hyaluronate 0.02
Dipropylene glycol 4.0
Sodium pyrrolidonecarboxylate 1.0
Fragrance composition for mental sedation of Example 9 0.3
Edetate disodium 0.01
Antioxidant Appropriate amount Preservative Appropriate amount of purified water Residue <Production>
A cream was obtained by a conventional method.

[Example 22] Emulsion
Compounding component amount (% by mass)
Squalane 5.0
Oleil Olate 3.0
Vaseline 2.0
Sorbitan sesquioleate 0.8
POE (20) oleyl ether 1.2
Evening primrose oil 0.5
1,3-butylene glycol 4.5
Ethanol 3.0
Carboxyvinyl polymer 0.2
Potassium hydroxide 0.1
L-arginine L-aspartate 0.01
Edetate 0.05
Fragrance composition for sedation of Example 8 0.3
Preservative Appropriate amount of purified water Residue <Production>
An emulsion was obtained by a conventional method.

[Example 23] Lotion
Compounding component amount (% by mass)
Cetanol 3.5
POE oleyl alcohol ether 2.0
2-Ethylhexyl-p-dimethylaminobenzoate 0.18
1,3-butylene glycol 9.5
Sodium pyrrolidonecarboxylate 0.5
Nicotinamide 0.3
Glycerin 5.0
Syringaldehyde 0.05
(P-methylphenylacetaldehyde)
Purified water residue <Production method>
A lotion was obtained by a conventional method.

[Example 24] Lotion
Compounding component amount (% by mass)
Cetanol 3.5
POE oleyl alcohol ether 2.0
2-Ethylhexyl-p-dimethylaminobenzoate 0.18
1,3-butylene glycol 9.5
Sodium pyrrolidonecarboxylate 0.5
Nicotinamide 0.3
Glycerin 5.0
Perfume composition for sedation of Example 5 0.05
Purified water residue <Production method>
A lotion was obtained by a conventional method.

Claims (8)

Terpynyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, chrysanthenone, lyral, γ-methylionone, iso-e super, Z-3-hexenyl salicylate, p- Use of one or more components selected from the group consisting of methylphenylacetaldehyde, ocimene, and γ-hexalactone . The use according to claim 1, wherein the sedation fragrance composition is a fragrance composition contained in an external composition. The use according to claim 2, wherein the product form of the composition for external use is a cosmetic. The use according to claim 1, wherein the scent fragrance composition is a room fragrance or deodorant, or a fragrance composition contained in an aroma candle . Perfume compositions comprising terpinyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, chrysanthenone, laral, γ-methylionone, iso-e-super, Z-3-hexenylsalicylate, p-methylphenylacetaldehyde, osymene, and A method for imparting a sedative effect in the perfume composition by blending one or more components selected from the group consisting of γ-hexalactone . The fragrance | flavor composition is the provision method of Claim 5 which is a fragrance | flavor composition contained in the composition for external use. The application method according to claim 6, wherein the product form of the composition for external use is a cosmetic. The method according to claim 5, wherein the fragrance composition is a fragrance composition contained in a room fragrance or deodorant or an aroma candle .

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