JP5291878B2 - 治療的免疫のためのコポリマー1を含む点眼ワクチン - Google Patents

治療的免疫のためのコポリマー1を含む点眼ワクチン Download PDF

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JP5291878B2
JP5291878B2 JP2006500369A JP2006500369A JP5291878B2 JP 5291878 B2 JP5291878 B2 JP 5291878B2 JP 2006500369 A JP2006500369 A JP 2006500369A JP 2006500369 A JP2006500369 A JP 2006500369A JP 5291878 B2 JP5291878 B2 JP 5291878B2
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copolymer
iop
cns
cop
disease
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JP2006515870A (ja
JP2006515870A5 (https=
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シュワルツ、ミカル アイゼンバッハ
バカラシュ、シャロン
フルガ、ヴァレンティン
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Yeda Research and Development Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
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    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2013IL-2
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/217IFN-gamma
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  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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JP2006500369A 2003-01-07 2004-01-06 治療的免疫のためのコポリマー1を含む点眼ワクチン Expired - Fee Related JP5291878B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43831003P 2003-01-07 2003-01-07
US60/438,310 2003-01-07
PCT/IL2004/000006 WO2004060265A2 (en) 2003-01-07 2004-01-06 Eye-drop vaccine containing copolymer 1 for therapeutic immunization

Publications (3)

Publication Number Publication Date
JP2006515870A JP2006515870A (ja) 2006-06-08
JP2006515870A5 JP2006515870A5 (https=) 2007-03-01
JP5291878B2 true JP5291878B2 (ja) 2013-09-18

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JP2006500369A Expired - Fee Related JP5291878B2 (ja) 2003-01-07 2004-01-06 治療的免疫のためのコポリマー1を含む点眼ワクチン

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US (2) US20070248569A1 (https=)
EP (1) EP1583506B1 (https=)
JP (1) JP5291878B2 (https=)
CN (2) CN102580069B (https=)
AT (1) ATE548045T1 (https=)
AU (1) AU2004203772B2 (https=)
CA (1) CA2512735C (https=)
ES (1) ES2386435T3 (https=)
IL (1) IL169552A (https=)
MX (1) MXPA05007329A (https=)
WO (1) WO2004060265A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2656463C (en) * 2006-06-28 2015-12-01 Yeda Research And Development Co. Ltd. Method of treatment of age-related macular degeneration
US8193147B2 (en) 2007-09-24 2012-06-05 Hadasit Medical Research Services & Development Ltd. Use of copolymer 1 for treatment of muscular dystrophy
EP2326342B1 (en) 2008-08-15 2021-10-06 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using interferon gamma to absorb fluid from the subretinal space
AU2010319559A1 (en) 2009-11-10 2012-05-31 Allegro Pharmaceuticals, Inc. Compositions and methods for inhibiting cellular adhesion or directing diagnostic or therapeutic agents to RGD binding sites
US11673914B2 (en) 2009-11-10 2023-06-13 Allegro Pharmaceuticals, LLC Peptide therapies for reduction of macular thickening
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
US8759302B2 (en) * 2010-03-16 2014-06-24 Teva Pharmaceutical Industries, Ltd. Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis
NZ703122A (en) 2010-10-11 2016-06-24 Teva Pharma Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
ES2601892T3 (es) 2011-04-21 2017-02-16 Mapi Pharma Limited Pentapolímero aleatorio para el tratamiento de enfermedades autoinmunes
KR20140101730A (ko) 2011-10-10 2014-08-20 테바 파마슈티컬 인더스트리즈 리미티드 글라티라머 아세테이트에 대한 임상 반응을 예측하는 데 유용한 단일 뉴클레오티드 다형성
WO2015038891A2 (en) * 2013-09-13 2015-03-19 The Penn State Research Foundation Functional peptide analogs of pedf
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
HUE071047T2 (hu) 2016-08-31 2025-07-28 Mapi Pharma Ltd Glatiramer-acetátot tartalmazó depórendszerek
CN106491614A (zh) * 2016-12-06 2017-03-15 郑州郑先医药科技有限公司 一种用于治疗脊髓损伤的西药组合及用途
WO2018136669A2 (en) * 2017-01-19 2018-07-26 Allegro Phamaceuticals, Inc. Therapeutic and neuroprotective peptides
CN110382052A (zh) 2017-03-26 2019-10-25 Mapi医药公司 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统
KR102874471B1 (ko) 2018-03-05 2025-10-31 매사추세츠 아이 앤드 이어 인퍼머리 콜로니 자극 인자의 표적화에 의한 녹내장 및 시신경병증 치료법
US20230181458A1 (en) * 2020-04-30 2023-06-15 Jeffrey E. Koziol Micro dosing of viral vaccines

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ZA93216B (en) 1992-01-17 1993-08-18 Solvay Animal Health Inc Vaccine containing acemannan as an adjuvant.
US5571515A (en) * 1994-04-18 1996-11-05 The Wistar Institute Of Anatomy & Biology Compositions and methods for use of IL-12 as an adjuvant
IL113812A (en) 1994-05-24 2000-06-29 Yeda Res & Dev Copolymer-1 pharmaceutical compositions containing it and its use
US6214791B1 (en) * 1997-01-10 2001-04-10 Yeda Research And Development Co. Ltd. Treatment of multiple sclerosis through ingestion or inhalation of copolymer-1
US6153182A (en) * 1997-12-19 2000-11-28 Uab Research Foundation Lymphotactin as an adjuvant
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US6616925B1 (en) * 1998-04-02 2003-09-09 I.D.M. Immuno-Designed Molecules Combined preparation for the treatment of neoplasic diseases or of infectious diseases
JP2003517452A (ja) * 1999-02-05 2003-05-27 アルク−アベル・アー/エス 新規粘膜デリバリーシステム
PL364983A1 (en) * 1999-08-24 2004-12-27 Teva Pharmaceutical Industries, Ltd. A vaccine composition and method of using the same
PT1248643E (pt) * 2000-01-20 2005-10-31 Yeda Res & Dev Utilizacao de copolimero 1 e peptidos e polipeptidos congeneres e de celulas t tratadas co estes compostos para terapia neuroprotectora
DK1294390T3 (da) 2000-06-07 2006-04-03 Yeda Res & Dev Anvendelse af copolymer 1 og beslægtede peptider og polypeptider og T-celelr behandlet dermed til neurobeskyttelse mod glutamattoksicitet
IL160105A0 (en) * 2001-12-06 2004-06-20 Yeda Res & Dev Vaccine for treatment of motor neurone diseases
CA2540701A1 (en) * 2003-09-29 2005-04-07 Chugai Seiyaku Kabushiki Kaisha Proteins expressed in nk cells
JP4501562B2 (ja) 2004-07-09 2010-07-14 旭硝子株式会社 積層膜付き基材およびその製造方法

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IL169552A (en) 2012-05-31
CN102580069A (zh) 2012-07-18
HK1084034A1 (en) 2006-07-21
ATE548045T1 (de) 2012-03-15
US8895501B2 (en) 2014-11-25
CN102580069B (zh) 2015-09-30
WO2004060265A2 (en) 2004-07-22
AU2004203772B2 (en) 2009-07-16
AU2004203772A1 (en) 2004-07-22
EP1583506B1 (en) 2012-03-07
CA2512735C (en) 2016-03-08
WO2004060265A3 (en) 2005-09-22
JP2006515870A (ja) 2006-06-08
US20090214470A1 (en) 2009-08-27
EP1583506A2 (en) 2005-10-12
US20070248569A1 (en) 2007-10-25
MXPA05007329A (es) 2005-09-30
CA2512735A1 (en) 2004-07-22
CN1758922A (zh) 2006-04-12
EP1583506A4 (en) 2009-01-07
ES2386435T3 (es) 2012-08-21

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