JP5256049B2 - 抗癌剤 - Google Patents

抗癌剤 Download PDF

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Publication number
JP5256049B2
JP5256049B2 JP2008556382A JP2008556382A JP5256049B2 JP 5256049 B2 JP5256049 B2 JP 5256049B2 JP 2008556382 A JP2008556382 A JP 2008556382A JP 2008556382 A JP2008556382 A JP 2008556382A JP 5256049 B2 JP5256049 B2 JP 5256049B2
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JP
Japan
Prior art keywords
chroman
tetramethyl
acid
dimethylnonanyl
succinate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2008556382A
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English (en)
Japanese (ja)
Other versions
JP2009538823A (ja
JP2009538823A5 (https=
Inventor
チン−シー チェン，
ダシェン ワン，
Original Assignee
ザ オハイオ ステート ユニバーシティー リサーチ ファウンデーション
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Application filed by ザ オハイオ ステート ユニバーシティー リサーチ ファウンデーション filed Critical ザ オハイオ ステート ユニバーシティー リサーチ ファウンデーション
Publication of JP2009538823A publication Critical patent/JP2009538823A/ja
Publication of JP2009538823A5 publication Critical patent/JP2009538823A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
JP2008556382A 2006-02-21 2007-02-21 抗癌剤 Expired - Fee Related JP5256049B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77510706P 2006-02-21 2006-02-21
US60/775,107 2006-02-21
PCT/US2007/004337 WO2007098139A2 (en) 2006-02-21 2007-02-21 Anticancer agents

Publications (3)

Publication Number Publication Date
JP2009538823A JP2009538823A (ja) 2009-11-12
JP2009538823A5 JP2009538823A5 (https=) 2011-03-03
JP5256049B2 true JP5256049B2 (ja) 2013-08-07

Family

ID=38437941

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008556382A Expired - Fee Related JP5256049B2 (ja) 2006-02-21 2007-02-21 抗癌剤

Country Status (6)

Country Link
US (2) US20080009545A1 (https=)
EP (1) EP1986635A4 (https=)
JP (1) JP5256049B2 (https=)
AU (1) AU2007217810B2 (https=)
CA (1) CA2643546A1 (https=)
WO (1) WO2007098139A2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007143081A2 (en) 2006-06-02 2007-12-13 The Ohio State University Research Foundation Therapeutic agents for the treatment of lymphoid malignancies
CA2726175A1 (en) 2008-05-27 2009-12-23 Memorial Sloan-Kettering Cancer Center Models for combinatorial perturbations of living biological systems
US8461362B2 (en) 2009-04-13 2013-06-11 The Ohio State University Research Foundation Protein phosphatase 2A-activating agents
WO2010121111A1 (en) * 2009-04-17 2010-10-21 The Ohio State University Research Foundation Antiadhesion agents
US8309768B2 (en) 2010-11-29 2012-11-13 The Ohio State University Research Foundation FTY720-derived anticancer agents
US20140197449A1 (en) * 2013-01-14 2014-07-17 Electronics And Telecommunications Research Institute Semiconductor rectifier device

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2680749A (en) * 1951-12-01 1954-06-08 Eastman Kodak Co Water-soluble tocopherol derivatives
US3459774A (en) * 1967-02-06 1969-08-05 Eisai Co Ltd Method of producing alpha-tocopheryl acid succinate
DE2822324C3 (de) * 1978-05-22 1981-02-26 Basf Ag, 6700 Ludwigshafen Herstellung von Vitamin-E-Trockenpulver
JPS59222415A (ja) * 1983-05-31 1984-12-14 Kuraray Co Ltd 免疫調節剤
US4751224A (en) * 1983-07-21 1988-06-14 Brown University Research Foundation Treatment of metastasis
US4938949A (en) * 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
US6335358B1 (en) * 1995-04-12 2002-01-01 President And Fellows Of Harvard College Lactacystin analogs
WO1997024112A1 (en) * 1995-12-28 1997-07-10 Yoshitomi Pharmaceutical Industries, Ltd. External preparation
US6476004B1 (en) * 1996-07-18 2002-11-05 Mitsubishi Pharma Corporation Pharmaceutical composition
US6004656A (en) * 1997-11-14 1999-12-21 3M Innovative Properties Company Color changeable device
US6703384B2 (en) * 1998-09-23 2004-03-09 Research Development Foundation Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof
US6770672B1 (en) * 1998-09-23 2004-08-03 Research Development Foundation Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof
DK1115398T3 (da) * 1998-09-23 2010-08-16 Res Dev Foundation Tocopheroler, tocotrienoler, andre chroman- og sidekædederivater og anvendelser deraf
RU2263672C2 (ru) * 2000-02-11 2005-11-10 Рисерч Дивелопмент Фаундейшн Токоферолы, токотриенолы, другие хроманы и производные по боковым цепям и их применение
JP2004538304A (ja) * 2001-07-27 2004-12-24 ユニバーシティー オブ ロチェスター アンドロゲンレセプターのビタミンｅ阻害および前立腺癌細胞中の前立腺特異的抗原の発現
US6858227B1 (en) * 2001-11-21 2005-02-22 Sonus Pharmaceuticals, Inc. Vitamin E conjugates
US20050215531A1 (en) * 2002-05-16 2005-09-29 Thomas Baumruker Use of edg receptor binding agents in cancer
AU2004271804B2 (en) * 2003-09-12 2011-01-06 Newron Sweden Ab Treatment of disorders of the nervous system
WO2005033093A1 (en) * 2003-09-19 2005-04-14 Galileo Pharmaceuticals, Inc. 7,8-bicycloalkyl-chroman derivatives
BRPI0619894B8 (pt) * 2005-12-15 2021-05-25 Mitsubishi Tanabe Pharma Corp composto de amina e composição farmacêutica
JP5341754B2 (ja) * 2007-06-14 2013-11-13 田辺三菱製薬株式会社 アミン化合物及びその医薬用途

Also Published As

Publication number Publication date
WO2007098139A2 (en) 2007-08-30
CA2643546A1 (en) 2007-08-30
EP1986635A4 (en) 2009-04-22
US20100273871A1 (en) 2010-10-28
EP1986635A2 (en) 2008-11-05
JP2009538823A (ja) 2009-11-12
WO2007098139A3 (en) 2008-11-20
AU2007217810B2 (en) 2012-10-11
AU2007217810A1 (en) 2007-08-30
US20080009545A1 (en) 2008-01-10

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