JP5253999B2 - 腫瘍診断と治療のための表面関連抗原の同定 - Google Patents

腫瘍診断と治療のための表面関連抗原の同定 Download PDF

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Publication number
JP5253999B2
JP5253999B2 JP2008502334A JP2008502334A JP5253999B2 JP 5253999 B2 JP5253999 B2 JP 5253999B2 JP 2008502334 A JP2008502334 A JP 2008502334A JP 2008502334 A JP2008502334 A JP 2008502334A JP 5253999 B2 JP5253999 B2 JP 5253999B2
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tumor
nucleic acid
expression
associated antigen
specific
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Expired - Lifetime
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Japanese (ja)
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JP2008537546A5 (enExample
JP2008537546A (ja
Inventor
サヒン，ウグール
テューレツィ，エツレム
コスロースキ，ミヒャエル
ヘルフテンバイン，ゲールト
ユーセナー，ディルク
シュリューター，フォルカー
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Ganymed Pharmaceuticals GmbH
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Cell Biology (AREA)
JP2008502334A 2005-03-24 2006-03-23 腫瘍診断と治療のための表面関連抗原の同定 Expired - Lifetime JP5253999B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005013846A DE102005013846A1 (de) 2005-03-24 2005-03-24 Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
DE102005013846.2 2005-03-24
PCT/EP2006/002695 WO2006100089A2 (de) 2005-03-24 2006-03-23 Identifizierung von oberflächen-assoziierten antigenen für die tumordiagnose und -therapie

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2012083549A Division JP5731436B2 (ja) 2005-03-24 2012-04-02 腫瘍診断と治療のための表面関連抗原の同定
JP2012258431A Division JP5779167B2 (ja) 2005-03-24 2012-11-27 腫瘍診断と治療のための表面関連抗原の同定

Publications (3)

Publication Number Publication Date
JP2008537546A JP2008537546A (ja) 2008-09-18
JP2008537546A5 JP2008537546A5 (enExample) 2009-04-30
JP5253999B2 true JP5253999B2 (ja) 2013-07-31

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Family Applications (5)

Application Number Title Priority Date Filing Date
JP2008502334A Expired - Lifetime JP5253999B2 (ja) 2005-03-24 2006-03-23 腫瘍診断と治療のための表面関連抗原の同定
JP2012083549A Expired - Lifetime JP5731436B2 (ja) 2005-03-24 2012-04-02 腫瘍診断と治療のための表面関連抗原の同定
JP2012258431A Expired - Lifetime JP5779167B2 (ja) 2005-03-24 2012-11-27 腫瘍診断と治療のための表面関連抗原の同定
JP2014005640A Expired - Lifetime JP5922159B2 (ja) 2005-03-24 2014-01-16 腫瘍診断と治療のための表面関連抗原の同定
JP2016032631A Expired - Lifetime JP6174177B2 (ja) 2005-03-24 2016-02-24 腫瘍診断と治療のための表面関連抗原の同定

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2012083549A Expired - Lifetime JP5731436B2 (ja) 2005-03-24 2012-04-02 腫瘍診断と治療のための表面関連抗原の同定
JP2012258431A Expired - Lifetime JP5779167B2 (ja) 2005-03-24 2012-11-27 腫瘍診断と治療のための表面関連抗原の同定
JP2014005640A Expired - Lifetime JP5922159B2 (ja) 2005-03-24 2014-01-16 腫瘍診断と治療のための表面関連抗原の同定
JP2016032631A Expired - Lifetime JP6174177B2 (ja) 2005-03-24 2016-02-24 腫瘍診断と治療のための表面関連抗原の同定

Country Status (6)

Country Link
US (4) US9090940B2 (enExample)
EP (5) EP2311487A3 (enExample)
JP (5) JP5253999B2 (enExample)
DE (1) DE102005013846A1 (enExample)
ES (1) ES2537319T3 (enExample)
WO (1) WO2006100089A2 (enExample)

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DE102005013846A1 (de) 2005-03-24 2006-10-05 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
DE102006060824B4 (de) * 2006-12-21 2011-06-01 Johannes-Gutenberg-Universität Mainz Nachweis von individuellen T-Zell-Reaktionsmustern gegen Tumor-assoziierte Antigene (TAA) in Tumorpatienten als Basis für die individuelle therapeutische Vakzinierung von Patienten
EP2060583A1 (en) * 2007-10-23 2009-05-20 Ganymed Pharmaceuticals AG Identification of tumor-associated markers for diagnosis and therapy
EP2249159A1 (en) * 2009-04-29 2010-11-10 Ganymed Pharmaceuticals AG Identification of tumor-associated markers for diagnosis and therapy
ES2729051T3 (es) 2009-07-29 2019-10-30 Kai Pharmaceuticals Inc Agentes terapéuticos para reducir los niveles de hormona paratiroidea
US8486657B2 (en) * 2010-03-22 2013-07-16 Xiaohong Cai Anti-preproprotein and anti-preprotein antibodies as immunohistochemical markers
TW201302800A (zh) * 2011-06-10 2013-01-16 腫瘤療法 科學股份有限公司 Ｓｅｍａ５ｂ胜肽及含其之疫苗
SG11201503918XA (en) * 2012-12-04 2015-06-29 Oncotherapy Science Inc Sema5b peptides and vaccines containing the same
US11203783B2 (en) 2013-11-21 2021-12-21 Repertoire Genesis Incorporation T cell receptor and B cell receptor repertoire analysis system, and use of same in treatment and diagnosis
US11596652B2 (en) 2015-02-18 2023-03-07 Enlivex Therapeutics R&D Ltd Early apoptotic cells for use in treating sepsis
US11318163B2 (en) 2015-02-18 2022-05-03 Enlivex Therapeutics Ltd Combination immune therapy and cytokine control therapy for cancer treatment
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US11497767B2 (en) 2015-02-18 2022-11-15 Enlivex Therapeutics R&D Ltd Combination immune therapy and cytokine control therapy for cancer treatment
US11000548B2 (en) 2015-02-18 2021-05-11 Enlivex Therapeutics Ltd Combination immune therapy and cytokine control therapy for cancer treatment
US11512289B2 (en) 2015-02-18 2022-11-29 Enlivex Therapeutics Rdo Ltd Combination immune therapy and cytokine control therapy for cancer treatment
EP4140492A1 (en) 2015-04-21 2023-03-01 Enlivex Therapeutics Rdo Ltd Therapeutic pooled blood apoptotic cell preparations and uses thereof
GB201520564D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
GB201520568D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd Peptides
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US20170199961A1 (en) 2015-12-16 2017-07-13 Gritstone Oncology, Inc. Neoantigen Identification, Manufacture, and Use
EP3402571A4 (en) 2016-01-15 2019-08-28 The J. David Gladstone Institutes METHOD FOR THE TREATMENT OF DISORDERS BY METABOLIC CONTROL OF T-CELL DIFFERENTIATION
JP6884155B2 (ja) 2016-02-18 2021-06-09 エンリヴェックス セラピューティクス リミテッド 癌治療のための併用免疫療法及びサイトカイン制御療法
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Also Published As

Publication number Publication date
EP2314310A3 (de) 2011-08-10
EP2314309A2 (de) 2011-04-27
EP2311487A2 (de) 2011-04-20
US20150368723A1 (en) 2015-12-24
US20170052187A1 (en) 2017-02-23
US20140017679A1 (en) 2014-01-16
WO2006100089A3 (de) 2007-01-11
ES2537319T3 (es) 2015-06-05
JP5731436B2 (ja) 2015-06-10
EP2327417A2 (de) 2011-06-01
EP2314310A2 (de) 2011-04-27
EP1861118A2 (de) 2007-12-05
JP2014139171A (ja) 2014-07-31
US10036753B2 (en) 2018-07-31
EP2327417B1 (de) 2015-05-06
JP5779167B2 (ja) 2015-09-16
US20090214550A1 (en) 2009-08-27
JP2016138115A (ja) 2016-08-04
JP6174177B2 (ja) 2017-08-02
EP2311487A3 (de) 2011-08-10
JP2008537546A (ja) 2008-09-18
US9090940B2 (en) 2015-07-28
US10302647B2 (en) 2019-05-28
DE102005013846A1 (de) 2006-10-05
EP2327417A3 (de) 2011-08-03
JP5922159B2 (ja) 2016-05-24
EP1861118B1 (de) 2015-05-06
WO2006100089A2 (de) 2006-09-28
US9194004B2 (en) 2015-11-24
JP2012207020A (ja) 2012-10-25
JP2013099331A (ja) 2013-05-23
EP2314309A3 (de) 2011-08-10

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