JP5243535B2 - イメージ内のウィルス顆粒を集計及び区分する方法 - Google Patents
イメージ内のウィルス顆粒を集計及び区分する方法 Download PDFInfo
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- JP5243535B2 JP5243535B2 JP2010510391A JP2010510391A JP5243535B2 JP 5243535 B2 JP5243535 B2 JP 5243535B2 JP 2010510391 A JP2010510391 A JP 2010510391A JP 2010510391 A JP2010510391 A JP 2010510391A JP 5243535 B2 JP5243535 B2 JP 5243535B2
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- G06V20/695—Preprocessing, e.g. image segmentation
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Description
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Claims (4)
- イメージ内において、細胞内のウィルス顆粒を集計し、区分する方法であって、該方法は、
その中に多数の対象物を有するイメージを提供するステップと、
円形の対象物を同定するステップと、
円形の対象物を半径範囲に基づいてグループに振り分けるステップと、
円形のウィルス顆粒の半径密度プロファイル分布を特定するステップと、
半径密度プロファイル分布から形成され得る楕円形の対象物を同定するステップと、
同定された楕円形の対象物を半径範囲に基づいてグループに振り分けるステップと、
円形及び楕円形の対象物の選択されたグループの半径密度プロファイル分布に基づき、振り分けられた円形及び楕円形の対象物からウィルス顆粒を同定するステップと、
薬剤にウィルス顆粒を曝露するステップと、
該薬剤への曝露後に、ウィルス顆粒を半径範囲に基づいてグループに振り分けるステップと、
該薬剤への曝露前の半径密度プロファイルの分布と曝露後の半径密度プロファイルの分布との間の差異を分析するステップとを含むことを特徴とする方法。 - 請求項1に記載の方法であって、前記曝露後のイメージ内の対象物の寸法の分布の変化を分析するステップを更に含む方法。
- 請求項1に記載の方法であって、化学物質に曝露する前後における、グループとなった対象物の量的な差異を特定するステップを更に含む方法。
- 請求項1に記載の方法であって、ウィルス顆粒の形態学的な構造を分析するステップを更に含む方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US94087007P | 2007-05-30 | 2007-05-30 | |
US60/940,870 | 2007-05-30 | ||
PCT/US2008/061499 WO2008150588A1 (en) | 2007-05-30 | 2008-04-25 | A method for counting and segmenting viral particles in an image |
Publications (2)
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JP2010529428A JP2010529428A (ja) | 2010-08-26 |
JP5243535B2 true JP5243535B2 (ja) | 2013-07-24 |
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Application Number | Title | Priority Date | Filing Date |
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JP2010510391A Active JP5243535B2 (ja) | 2007-05-30 | 2008-04-25 | イメージ内のウィルス顆粒を集計及び区分する方法 |
Country Status (19)
Country | Link |
---|---|
US (1) | US8224059B2 (ja) |
EP (1) | EP2149105B1 (ja) |
JP (1) | JP5243535B2 (ja) |
KR (1) | KR101343749B1 (ja) |
CN (1) | CN101681427B (ja) |
AU (1) | AU2008260410B2 (ja) |
BR (1) | BRPI0811951A2 (ja) |
CA (1) | CA2688153C (ja) |
DK (1) | DK2149105T3 (ja) |
ES (1) | ES2835175T3 (ja) |
HK (1) | HK1137254A1 (ja) |
HU (1) | HUE052662T2 (ja) |
MX (1) | MX2009012265A (ja) |
MY (1) | MY153016A (ja) |
PL (1) | PL2149105T3 (ja) |
PT (1) | PT2149105T (ja) |
RU (1) | RU2461063C2 (ja) |
WO (1) | WO2008150588A1 (ja) |
ZA (1) | ZA200907666B (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8775998B2 (en) | 2010-12-09 | 2014-07-08 | Panasonic Corporation | Support device of three-dimensional integrated circuit and method thereof |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
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KR101245923B1 (ko) * | 2005-04-15 | 2013-03-20 | 인텔리전트 바이러스 이미징 아이엔씨. | 세포 구조 및 세포 구조 내 성분 분석 방법 |
US8712140B2 (en) * | 2005-04-15 | 2014-04-29 | Intelligent Virus Imaging Inc. | Method of analyzing cell structures and their components |
US8712141B2 (en) * | 2007-05-30 | 2014-04-29 | Intelligent Virus Imagaing Inc. | Method for counting and segmenting viral particles in an image |
CN103514481A (zh) * | 2012-06-20 | 2014-01-15 | 天津三星电机有限公司 | 一种基于图像的制品数量快速测量方法及其装置 |
BR112017022551B1 (pt) * | 2015-12-18 | 2022-05-03 | Intelligent Virus Imaging Inc | Quantificação de alta precisão de partículas subvisíveis |
RU2626145C1 (ru) * | 2016-01-27 | 2017-07-21 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Оренбургский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО ОрГМУ Минздрава России) | Способ оценки содержания белков межклеточного матрикса в регенерирующих тканях при анализе цифровых изображений иммуногистохимических микропрепаратов в программе adobe® photoshop® |
US10451566B2 (en) * | 2016-09-30 | 2019-10-22 | Intelligent Virus Imaging Inc. | Method for quantification of purity of sub-visible particle samples |
MA44418B1 (fr) * | 2017-03-02 | 2021-11-30 | Intelligent Virus Imaging Inc | Procédé permettant la mesure quantitative de contenu particulaire à l'aide d'une imagerie à l'état hydraté |
RU2750591C1 (ru) * | 2020-05-12 | 2021-06-29 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Ижевская государственная медицинская академия" | Способ определения степени окраски эндотелиальных клеток |
CN111795986A (zh) * | 2020-05-20 | 2020-10-20 | 万秋花 | 应用外形搜索的病毒临床检验检测平台 |
CN112288684B (zh) * | 2020-07-15 | 2021-06-25 | 华北理工大学 | 应用密度分析的致病判断系统及方法 |
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DE59807899D1 (de) * | 1997-12-18 | 2003-05-15 | Infineon Technologies Ag | Vorrichtung zur bilderfassung |
JP4069545B2 (ja) * | 1999-05-19 | 2008-04-02 | 株式会社日立製作所 | 電子顕微方法及びそれを用いた電子顕微鏡並び生体試料検査方法及び生体検査装置 |
RU2168206C1 (ru) * | 2000-06-30 | 2001-05-27 | Зайцев Павел Анатольевич | Способ сканирования рисунка кожных линий и устройство для его осуществления |
JP4012813B2 (ja) * | 2002-11-27 | 2007-11-21 | 株式会社日立ハイテクノロジーズ | 透過型電子顕微鏡及び試料観察方法 |
JP4154300B2 (ja) * | 2003-09-08 | 2008-09-24 | 株式会社日立ハイテクノロジーズ | 透過電子顕微鏡システムおよびそれを用いた検査方法 |
US20070099276A1 (en) * | 2003-10-25 | 2007-05-03 | David Ott | Retrovirus-like particles and retroviral vaccines |
MY148115A (en) * | 2005-10-12 | 2013-02-28 | Intelligent Virus Imaging Inc | Identification and classification of virus particles in textured electron micrographs |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8775998B2 (en) | 2010-12-09 | 2014-07-08 | Panasonic Corporation | Support device of three-dimensional integrated circuit and method thereof |
Also Published As
Publication number | Publication date |
---|---|
ES2835175T3 (es) | 2021-06-22 |
KR20100025545A (ko) | 2010-03-09 |
DK2149105T3 (da) | 2021-02-01 |
PL2149105T3 (pl) | 2021-05-17 |
MY153016A (en) | 2014-12-31 |
BRPI0811951A2 (pt) | 2016-10-04 |
CN101681427B (zh) | 2012-12-05 |
US20100151446A1 (en) | 2010-06-17 |
PT2149105T (pt) | 2020-12-15 |
RU2461063C2 (ru) | 2012-09-10 |
AU2008260410A1 (en) | 2008-12-11 |
EP2149105A4 (en) | 2013-09-25 |
AU2008260410B2 (en) | 2012-05-03 |
MX2009012265A (es) | 2009-12-01 |
CA2688153A1 (en) | 2008-12-11 |
HK1137254A1 (en) | 2010-07-23 |
HUE052662T2 (hu) | 2021-05-28 |
WO2008150588A1 (en) | 2008-12-11 |
ZA200907666B (en) | 2010-07-28 |
EP2149105B1 (en) | 2020-11-18 |
US8224059B2 (en) | 2012-07-17 |
JP2010529428A (ja) | 2010-08-26 |
CA2688153C (en) | 2015-03-31 |
KR101343749B1 (ko) | 2013-12-19 |
RU2009149093A (ru) | 2011-07-10 |
EP2149105A1 (en) | 2010-02-03 |
CN101681427A (zh) | 2010-03-24 |
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