JP5225844B2 - 半月板断裂を修復するためのコラーゲン膜材料のシート - Google Patents
半月板断裂を修復するためのコラーゲン膜材料のシート Download PDFInfo
- Publication number
- JP5225844B2 JP5225844B2 JP2008529334A JP2008529334A JP5225844B2 JP 5225844 B2 JP5225844 B2 JP 5225844B2 JP 2008529334 A JP2008529334 A JP 2008529334A JP 2008529334 A JP2008529334 A JP 2008529334A JP 5225844 B2 JP5225844 B2 JP 5225844B2
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- JP
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- Prior art keywords
- sheet
- membrane material
- collagen
- collagen membrane
- material according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/005—Ingredients of undetermined constitution or reaction products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/044—Collagen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/902—Method of implanting
- Y10S623/908—Bone
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Surgery (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Botany (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71336005P | 2005-09-02 | 2005-09-02 | |
| US60/713,360 | 2005-09-02 | ||
| PCT/US2006/034329 WO2007028078A2 (en) | 2005-09-02 | 2006-09-01 | Method of repairing meniscal tears |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012201621A Division JP2012236112A (ja) | 2005-09-02 | 2012-09-13 | 半月板断裂を修復するためのコラーゲン膜材料のシート |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009506841A JP2009506841A (ja) | 2009-02-19 |
| JP2009506841A5 JP2009506841A5 (enExample) | 2009-10-22 |
| JP5225844B2 true JP5225844B2 (ja) | 2013-07-03 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008529334A Expired - Fee Related JP5225844B2 (ja) | 2005-09-02 | 2006-09-01 | 半月板断裂を修復するためのコラーゲン膜材料のシート |
| JP2012201621A Withdrawn JP2012236112A (ja) | 2005-09-02 | 2012-09-13 | 半月板断裂を修復するためのコラーゲン膜材料のシート |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012201621A Withdrawn JP2012236112A (ja) | 2005-09-02 | 2012-09-13 | 半月板断裂を修復するためのコラーゲン膜材料のシート |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8084428B2 (enExample) |
| EP (1) | EP1937293B1 (enExample) |
| JP (2) | JP5225844B2 (enExample) |
| CN (1) | CN101252948A (enExample) |
| AU (1) | AU2006287197B2 (enExample) |
| CA (1) | CA2621153C (enExample) |
| ES (1) | ES2439943T3 (enExample) |
| PL (1) | PL1937293T3 (enExample) |
| RU (1) | RU2421173C2 (enExample) |
| WO (1) | WO2007028078A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1948258B1 (en) * | 2005-10-24 | 2013-01-02 | Ed. Geistlich Söhne Ag Für Chemische Industrie | Method and device for synovial cell-charged collagen membrane or gel |
| WO2008131293A2 (en) | 2007-04-19 | 2008-10-30 | Collengin, Inc. | Oriented collagen-based materials, films and methods of making same |
| US10086079B2 (en) | 2008-08-11 | 2018-10-02 | Fibralign Corporation | Biocomposites and methods of making the same |
| US8513382B2 (en) | 2008-08-11 | 2013-08-20 | Fibralign Corporation | Biocomposites and methods of making the same |
| CN101756503A (zh) * | 2008-11-07 | 2010-06-30 | 南通芯迎设计服务有限公司 | 一种多功能桌子 |
| CA2749858C (en) * | 2009-01-16 | 2017-12-12 | Geistlich Pharma Ag | Method and membrane for skin regeneration |
| US10806833B1 (en) | 2009-05-11 | 2020-10-20 | Integra Lifesciences Corporation | Adherent resorbable matrix |
| US20110059178A1 (en) * | 2009-09-08 | 2011-03-10 | Musculoskeletal Transplant Foundation Inc. | Tissue Engineered Meniscus Repair Composition |
| WO2011031642A2 (en) * | 2009-09-08 | 2011-03-17 | Musculoskeletal Transplant Foundation Inc. | Tissue engineered meniscus repair composition |
| US10065046B2 (en) | 2010-07-15 | 2018-09-04 | Fibralign Corporation | Conductive biopolymer implant for enhancing tissue repair and regeneration using electromagnetic fields |
| US9724308B2 (en) | 2010-09-10 | 2017-08-08 | Fibralign Corporation | Biodegradable multilayer constructs |
| CN102229647B (zh) * | 2011-06-09 | 2013-02-20 | 北京大学第三医院 | 滑膜间充质干细胞亲和多肽修饰植入人体支架的方法 |
| US10238769B2 (en) | 2011-10-11 | 2019-03-26 | Fibralign Corporation | Graft for directed vascular and lymphatic regeneration and methods to guide endothelial cell assembly |
| CN102716515B (zh) * | 2012-07-02 | 2014-01-29 | 陕西博鸿生物科技有限公司 | 一种修复半月板撕裂的生物材料及其制备方法 |
| WO2014052912A1 (en) | 2012-09-28 | 2014-04-03 | Scripps Health | Methods of differentiating stem cells into chondrocytes |
| EP3054960B1 (en) | 2013-10-10 | 2022-12-21 | Fibralign Corporation | Method and device for lymphedema treatment |
| CN105903079A (zh) * | 2016-05-20 | 2016-08-31 | 中国人民解放军总医院 | 半月板基质来源的三维多孔海绵状支架、制备方法及应用 |
| US11857576B2 (en) * | 2017-12-07 | 2024-01-02 | Vericel Corporation | Compositions and methods for repairing cartilage defects |
| US12427228B2 (en) | 2018-10-05 | 2025-09-30 | Hiroshima University | Meniscus regeneration material |
| EP4103259A4 (en) | 2020-02-11 | 2024-02-28 | Embody, Inc. | Surgical cannula with removable pressure seal |
| AU2021220863B2 (en) | 2020-02-11 | 2023-12-14 | Embody, Inc. | Implant delivery device |
| EP4103069A4 (en) | 2020-02-11 | 2024-06-05 | Embody Inc. | SURGICAL ANCHORING DEVICE, DEVELOPMENT DEVICE AND METHOD OF USE |
| PL247461B1 (pl) | 2020-10-14 | 2025-07-07 | Kinga Ciemniewska-Gorzela | Kolagenowa kapa łąkotkowa i sposób wytwarzania kolagenowej kapy łąkotkowej |
| RU2761965C1 (ru) * | 2020-11-23 | 2021-12-14 | Александр Олегович Тутуров | Способ артроскопической рефиксации разрывов менисков при сочетанном повреждении связок коленного сустава |
| US11857170B2 (en) | 2022-03-04 | 2024-01-02 | Vericel Corporation | Methods and devices for repairing cartilage defects |
Family Cites Families (18)
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| US5206023A (en) * | 1991-01-31 | 1993-04-27 | Robert F. Shaw | Method and compositions for the treatment and repair of defects or lesions in cartilage |
| GB9400163D0 (en) * | 1994-01-06 | 1994-03-02 | Geistlich Soehne Ag | Membrane |
| US20030039695A1 (en) * | 2001-08-10 | 2003-02-27 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Collagen carrier of therapeutic genetic material, and method |
| US6352558B1 (en) * | 1996-02-22 | 2002-03-05 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method for promoting regeneration of surface cartilage in a damage joint |
| EP0896825B1 (en) * | 1997-08-14 | 2002-07-17 | Sulzer Innotec Ag | Composition and device for in vivo cartilage repair comprising nanocapsules with osteoinductive and/or chondroinductive factors |
| YU12201A (sh) | 1998-08-14 | 2005-06-10 | Verigen Transplantation Service International (Vtsi) Ag. | Metodi, instrumenti i materijali za transplantaciju ćelija hondrocita |
| US20040059416A1 (en) * | 1999-06-22 | 2004-03-25 | Murray Martha M. | Biologic replacement for fibrin clot |
| US6221109B1 (en) | 1999-09-15 | 2001-04-24 | Ed. Geistlich Söhne AG fur Chemische Industrie | Method of protecting spinal area |
| CZ301649B6 (cs) * | 2000-06-28 | 2010-05-12 | Ed. Geistlich Soehne Ag Fur Chemische Industrie Incorporated Under The Laws Of Switzerland | Trubice pro regeneraci nervu a zpusob jejich výroby |
| IT1318663B1 (it) | 2000-08-02 | 2003-08-27 | Mediolanum Farmaceutici Srl | Membrane di collagene a due facce di cui una organizzata a livellomacromolecolare. |
| EP1363685B1 (en) * | 2000-11-24 | 2007-08-08 | Universite Laval | Connective tissue substitutes, method of preparation and uses thereof |
| KR20040008125A (ko) * | 2001-01-30 | 2004-01-28 | 오르쏘젠 인크. | 활액 유도된 조직 또는 세포를 사용하여 관절 연골 내의결함 또는 병변을 치료 및 수복하기 위한 조성물 및 방법 |
| SK13892003A3 (sk) * | 2001-04-12 | 2004-07-07 | Verigen Transplantation Service International (Vtsi) Ag | Spôsob autológnej transplantácie |
| US6713085B2 (en) | 2001-04-27 | 2004-03-30 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method and membrane for mucosa regeneration |
| US6444222B1 (en) | 2001-05-08 | 2002-09-03 | Verigen Transplantation Services International Ag | Reinforced matrices |
| JP2003160506A (ja) * | 2001-08-10 | 2003-06-03 | Ed Geistlich Soehne Ag Fuer Chemische Industrie | 治療用遺伝物質のコラーゲン担体およびその方法 |
| CA2412012C (en) | 2001-11-20 | 2011-08-02 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Resorbable extracellular matrix containing collagen i and collagen ii for reconstruction of cartilage |
| US8657881B2 (en) * | 2004-04-20 | 2014-02-25 | Depuy Mitek, Llc | Meniscal repair scaffold |
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2006
- 2006-09-01 CN CNA2006800316648A patent/CN101252948A/zh active Pending
- 2006-09-01 AU AU2006287197A patent/AU2006287197B2/en not_active Ceased
- 2006-09-01 EP EP06802853.9A patent/EP1937293B1/en active Active
- 2006-09-01 US US12/064,444 patent/US8084428B2/en active Active
- 2006-09-01 PL PL06802853T patent/PL1937293T3/pl unknown
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- 2006-09-01 RU RU2008112185/14A patent/RU2421173C2/ru active
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|---|---|
| CN101252948A (zh) | 2008-08-27 |
| EP1937293B1 (en) | 2013-11-20 |
| ES2439943T3 (es) | 2014-01-27 |
| JP2009506841A (ja) | 2009-02-19 |
| US20090186062A1 (en) | 2009-07-23 |
| WO2007028078A2 (en) | 2007-03-08 |
| AU2006287197A1 (en) | 2007-03-08 |
| CA2621153C (en) | 2016-10-18 |
| JP2012236112A (ja) | 2012-12-06 |
| CA2621153A1 (en) | 2007-03-08 |
| EP1937293A2 (en) | 2008-07-02 |
| EP1937293A4 (en) | 2011-07-20 |
| US8084428B2 (en) | 2011-12-27 |
| PL1937293T3 (pl) | 2014-03-31 |
| WO2007028078A3 (en) | 2007-09-13 |
| RU2008112185A (ru) | 2009-10-10 |
| AU2006287197B2 (en) | 2013-02-14 |
| RU2421173C2 (ru) | 2011-06-20 |
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