JP5202332B2 - がんの治療のための化合物および方法 - Google Patents

がんの治療のための化合物および方法 Download PDF

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Publication number
JP5202332B2
JP5202332B2 JP2008550463A JP2008550463A JP5202332B2 JP 5202332 B2 JP5202332 B2 JP 5202332B2 JP 2008550463 A JP2008550463 A JP 2008550463A JP 2008550463 A JP2008550463 A JP 2008550463A JP 5202332 B2 JP5202332 B2 JP 5202332B2
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compound
alkyl
cancer
compound according
hours
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English (en)
Japanese (ja)
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JP2009527463A5 (OSRAM
JP2009527463A (ja
Inventor
ラルフ エー. ジンガロ
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ザ テキサス エー アンド エム ユニバーシティ システム
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/285—Arsenic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/66—Arsenic compounds
    • C07F9/70—Organo-arsenic compounds
    • C07F9/72—Aliphatic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/66—Arsenic compounds
    • C07F9/70—Organo-arsenic compounds
    • C07F9/80—Heterocyclic compounds
    • C07F9/82—Arsenic compounds containing one or more pyridine rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2008550463A 2006-01-13 2007-01-16 がんの治療のための化合物および方法 Expired - Fee Related JP5202332B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US75921806P 2006-01-13 2006-01-13
US60/759,218 2006-01-13
US76300806P 2006-01-26 2006-01-26
US60/763,008 2006-01-26
PCT/US2007/001127 WO2007082104A2 (en) 2006-01-13 2007-01-16 Compounds and methods for the treatment of cancer

Publications (3)

Publication Number Publication Date
JP2009527463A JP2009527463A (ja) 2009-07-30
JP2009527463A5 JP2009527463A5 (OSRAM) 2010-03-04
JP5202332B2 true JP5202332B2 (ja) 2013-06-05

Family

ID=38158019

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008550463A Expired - Fee Related JP5202332B2 (ja) 2006-01-13 2007-01-16 がんの治療のための化合物および方法

Country Status (10)

Country Link
US (2) US8222440B2 (OSRAM)
EP (1) EP1979368B1 (OSRAM)
JP (1) JP5202332B2 (OSRAM)
KR (2) KR20130129316A (OSRAM)
CN (2) CN101395166B (OSRAM)
AU (1) AU2007204831B2 (OSRAM)
CA (1) CA2636793C (OSRAM)
HK (1) HK1203512A1 (OSRAM)
IL (3) IL192738A0 (OSRAM)
WO (1) WO2007082104A2 (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2705467A1 (en) * 2007-12-12 2009-06-18 Ziopharm Oncology, Inc. Compounds and methods for the treatment of cancer
WO2010021928A1 (en) 2008-08-20 2010-02-25 Ziopharm Oncology, Inc. Organoarsenic compounds and methods for the treatment of cancer
WO2015085208A1 (en) * 2013-12-05 2015-06-11 Solasia Pharma K.K. Compounds and methods for the treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2255800T3 (da) 1997-11-10 2013-02-04 Sloan Kettering Inst Cancer Arsentrioxid til anvendelse ved behandling af leukæmi
EP1002537A1 (en) 1998-10-30 2000-05-24 Assistance Publique, Hopitaux De Paris Use of melarsoprol for the manufacture of a medicament for treating B-cell lymphoproliferative diseases, such as multiple myeloma
EP1474128B1 (en) * 2002-01-07 2016-06-01 Board Of Regents, The University Of Texas System S-dimethylarsino-thiosuccinic acid, s-dimethylarsino-2-thiobenzoic acid, s-(dimethylarsino)glutathione as treatments for cancer
TWI411431B (zh) * 2004-07-16 2013-10-11 Texas A & M Univ Sys 有機砷化合物、其用於治療癌症之用途及包含其之醫藥組成物

Also Published As

Publication number Publication date
AU2007204831B2 (en) 2013-10-03
JP2009527463A (ja) 2009-07-30
US20130143950A1 (en) 2013-06-06
CN104109177A (zh) 2014-10-22
US8222440B2 (en) 2012-07-17
IL226362A0 (en) 2013-06-27
KR20080106897A (ko) 2008-12-09
IL192738A0 (en) 2009-02-11
CA2636793A1 (en) 2007-07-19
KR101471498B1 (ko) 2014-12-10
EP1979368B1 (en) 2014-12-24
KR20130129316A (ko) 2013-11-27
AU2007204831A1 (en) 2007-07-19
HK1130804A1 (en) 2010-01-08
EP1979368A2 (en) 2008-10-15
US20090233894A1 (en) 2009-09-17
CN101395166A (zh) 2009-03-25
CN101395166B (zh) 2014-07-09
CA2636793C (en) 2014-07-08
IL226363A0 (en) 2013-06-27
WO2007082104A3 (en) 2007-10-18
WO2007082104A2 (en) 2007-07-19
HK1203512A1 (en) 2015-10-30

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