JP5156421B2 - Ultrasonic diagnostic equipment - Google Patents

Description

  The present invention relates to an ultrasonic diagnostic apparatus, and specifically, a tomographic image in which an elastic image representing the hardness or softness of a tissue of a subject is obtained on a living body simulation image such as an illustration or a photograph simulating the subject. The present invention relates to an ultrasonic diagnostic apparatus that displays or records a mark indicating a position in a superimposed manner.

  The ultrasonic diagnostic apparatus transmits ultrasonic waves to the inside of the subject via the ultrasonic probe and receives an ultrasonic echo signal corresponding to the structure of the living tissue from the inside of the subject. An image such as an image is generated and used for diagnosis.

  In recent years, as described in, for example, Patent Document 1, RF signal frame data is acquired while applying pressure to a subject with an ultrasonic probe by a manual or mechanical method, and a pair of acquisition times are different. Based on the RF signal frame data, the displacement of each part of the living body caused by the compression is obtained, and an elastic image representing the hardness or softness of the living tissue is generated based on the displacement data.

  By the way, in Patent Document 2, a tomographic image of a subject is displayed, and a probe mark representing a scanning position of a probe is provided at a position where a tomographic image on an illustration (body mark) image simulating a living body is acquired. It is described that it is displayed in a superimposed manner. If the tomographic image and the living body simulation image on which the probe mark is superimposed are recorded in association with each other, it is considered that the tomographic image can be easily associated with the examination site where the image is acquired after the ultrasonic examination.

JP 2000-060853 A JP 2007-202829 A

  However, the technique described in Patent Document 2 displays information such as an examination site by marking the living body simulated image on an elastic image, or records the living body simulated image in which the examination site is marked in association with the elasticity image. Is not considered.

  That is, the technique described in Patent Document 2 detects a living body simulated image by detecting the coordinates of the probe with a sensor such as a magnetic sensor attached to the ultrasonic probe and aligning it with the coordinates of the living body simulated image. The inspection site of the tomographic image is marked on the top. On the other hand, as described above, the elastic image is displaced in the tissue of the tomographic site by repeatedly applying pressure to the subject using, for example, an ultrasonic probe, or using pressure changes such as the pulsation of the subject. It is generated based on a pair of RF signal frame data obtained in the generated state. Therefore, it is difficult to detect that the elastic image has been properly acquired by the technique described in Patent Document 2, and it is difficult to grasp the acquisition position of the elastic image.

  Therefore, an object of the present invention is to realize an ultrasonic diagnostic apparatus capable of detecting a tomographic region of a subject from which an elasticity image has been acquired and displaying or recording an image obtained by superimposing the tomographic region on a living body simulated image.

  In order to solve the above-described problems, an ultrasonic diagnostic apparatus according to the present invention includes an ultrasonic probe that transmits and receives ultrasonic waves to and from a subject, and a reflected echo signal that is measured by the ultrasonic probe. A phasing / adding means for generating RF signal frame data of the tomographic part of the specimen and an elastic image for generating an elastic image representing the hardness or softness of the tissue of the tomographic part based on a pair of RF signal frame data having different acquisition times Configuration means, biological simulation image generation means for generating a biological simulation image that simulates a subject, a position sensor that is attached to an ultrasonic probe and detects the three-dimensional coordinate position and orientation of the probe, and a position sensor A tomographic part detecting means for detecting position information of a tomographic part of the subject based on an output from the tissue, a tissue displacement detecting means for detecting that the tissue of the tomographic part of the subject is displaced, and a displacement of the tissue is detected. When Based on the position information of the tomographic part of the specimen, the elasticity image acquisition mark is superimposed on the corresponding position on the living body simulated image, and the simulated image on which the mark is superimposed is displayed on the display or the displacement of the tissue is detected. And a means for recording in a memory in association with the elastic image generated at the time.

  That is, according to the present invention, by providing the tissue displacement detection means, it is possible to detect that the tissue of the tomographic site of the subject is displaced, so that it is detected that the elasticity image has been appropriately acquired. can do. Therefore, a mark can be superimposed on the position where the elastic image on the living body simulated image is acquired based on the position information of the tomographic part of the subject when this is detected. By displaying the simulated image with the mark superimposed on the display in real time, the examination efficiency can be improved, and by recording in the memory in association with the elastic image generated when the tissue displacement is detected , Can be linked efficiently to post-test diagnosis and treatment policy decisions.

In addition, the tissue displacement detection means can be configured in the following manner. First,
Of the three-dimensional coordinates of the ultrasonic probe detected by the position sensor attached to the ultrasonic probe, at least the position of the tomographic site is determined by a periodic change in coordinates on any of the coordinate axes corresponding to the direction of tissue displacement. Tissue displacement can be detected. This can be applied to the case where an elastic image is acquired while causing the tissue of the tomographic site to be displaced by repeatedly performing the compression / release operation of the probe on the subject. In this case, since the probe position is periodically displaced due to the compression / release operation, the three-dimensional coordinates of the probe position sensor are monitored, and at least on any coordinate axis corresponding to the tissue displacement direction. By detecting a periodic change in coordinates, the tissue displacement of the tomographic site can be detected.

  In addition, a tomographic image forming unit that generates a tomographic image of a tomographic region of the subject based on the RF signal frame data, a unit that sets a tracking point in the tomographic image, and a unit that detects the position of the tracking point are provided. The tissue displacement detection means can detect the displacement of the tissue at the tomographic site based on a periodic change in the direction corresponding to the displacement direction of the tissue at the position of the tracking point.

  This is not only when applying pressure to the subject with the probe, but also when acquiring elastic images by utilizing the fact that the tissue is displaced due to periodic changes in internal pressure caused by, for example, pulsation of blood vessels in the subject. It can be applied particularly effectively. That is, according to this, even when the probe position is fixed and the probe position does not move, if the displacement in the direction corresponding to the displacement direction of the tissue of the tracking point on the tomographic image is periodic, It can be detected that the tissue of the tomographic site is displaced.

  When a plurality of similar tracking points are set, the tissue displacement detection means measures the displacement of the distance in the direction corresponding to the tissue displacement direction between the plurality of tracking points, and periodically changes the measured value of the displacement. Thus, the displacement of the tissue at the tomographic site can be detected.

  In addition, in the case of including a correlation calculation unit that performs cross-correlation calculation of RF signal frame data, the tissue displacement detection unit, when the correlation coefficient obtained by the correlation calculation unit is larger than a preset threshold value, The displacement of the tissue at the tomographic site can be detected.

  That is, when the probe is appropriately moved to obtain a tomographic image, the correlation value obtained by the cross-correlation calculation of the pair of RF signal frame data is relatively low, whereas the probe causes the subject to be examined. When the compression / release operation is being performed, the correlation value is relatively high, and by detecting this, the displacement of the tissue at the tomographic site can be detected. However, when the probe position is fixed and there is no displacement in the tissue of the tomographic site, the pair of RF signal frame data almost coincide and the correlation value indicates the upper limit. Can be excluded.

  In addition, when a pressure sensor is provided on the contact surface of the ultrasonic probe with the subject, the tissue displacement detecting means can detect the displacement of the tissue at the tomographic site by a periodic change in the measurement value of the pressure sensor. it can. This can be applied to both the case where the probe performs the compression / release operation and the case where the change in the internal pressure of the subject is used. In either case, since the detection value of the pressure sensor changes periodically, the displacement of the tissue at the tomographic site can be detected by detecting this.

  ADVANTAGE OF THE INVENTION According to this invention, the ultrasonic diagnostic apparatus which can detect the tomographic site | part of the subject from which the elasticity image was acquired, and can display or record the image which superimposed this on the biological simulation image is realizable.

  Hereinafter, embodiments of an ultrasonic diagnostic apparatus to which the present invention is applied will be described. In the following description, the same functional parts are denoted by the same reference numerals, and redundant description is omitted.

  FIG. 1 is a block diagram showing the overall configuration of the ultrasonic diagnostic apparatus of the present embodiment. As shown in FIG. 1, the ultrasound diagnostic apparatus 1 includes an ultrasound probe 12 that is used while being in contact with the subject 10, and a time interval between the subject 10 and the ultrasound probe 12. A transmitter 14 that repeatedly transmits ultrasonic waves, a receiver 16 that receives time-series reflected echo signals generated from the subject 10, a transmission / reception controller 17 that controls the transmitter 14 and the receiver 16, and a receiver 16 Is provided with a phasing addition unit 18 for phasing and adding the reflected echo received in step (1).

  Further, based on the RF signal frame data from the phasing adder 18, a tomographic image constructing unit 20 that constitutes a tomographic image such as a black and white tomographic image of the subject, and an output signal of the tomographic image constructing unit 20 A black-and-white scan converter 22 is provided for conversion to suit the display of 26.

  Further, the RF signal frame data output from the phasing addition unit 18 is stored, the RF frame data selection unit 28 that selects at least two pieces of frame data, and the displacement measurement unit that measures the displacement of the living tissue of the subject 10. 30, an elastic information calculation unit 32 that obtains strain or elastic modulus from the displacement information measured by the displacement measurement unit 30, and an elastic image configuration unit that forms a color elastic image from the strain or elastic modulus calculated by the elastic information calculation unit 32 34 and a color scan converter 36 for converting the output signal of the elastic image construction unit 34 so as to match the display of the image display 26.

  Further, an image control unit 44 that outputs various control signals to each unit constituting the ultrasonic diagnostic apparatus, and an interface unit 42 that inputs an instruction from the examiner and outputs the instruction to the image control unit 44 are provided. .

  Here, the ultrasonic diagnostic apparatus 1 will be described in detail. The ultrasonic probe 12 is formed by arranging a plurality of transducers, and has a function of transmitting and receiving ultrasonic waves to and from the subject 10 via the transducers. The transmission unit 14 has a function of generating a transmission pulse for generating an ultrasonic wave by driving the ultrasonic probe 12 and setting a convergence point of the transmitted ultrasonic wave to a certain depth. Yes. The receiving unit 16 amplifies the reflected echo signal received by the ultrasonic probe 12 with a predetermined gain to generate an RF signal, that is, a received signal. The phasing adder 18 receives the RF signal amplified by the receiver 16 and performs phase control, and forms an ultrasonic beam at one point or a plurality of convergence points to generate RF signal frame data.

  The tomographic image construction unit 20 receives the RF signal frame data from the phasing addition unit 18 and performs signal processing such as gain correction, log compression, detection, contour enhancement, and filter processing to obtain tomographic image data. . The monochrome scan converter 22 also includes an A / D converter that converts tomographic image data from the tomographic image construction unit 20 into a digital signal, a frame memory that stores a plurality of converted tomographic image data in time series, and a control. It is configured to include a controller. The black and white scan converter 22 acquires tomographic frame data in the subject stored in the frame memory as one image, and reads the acquired image frame data in synchronization with the television.

  The RF frame data selection unit 28 stores a plurality of RF signal frame data from the phasing addition unit 18, and selects one set, that is, two RF signal frame data from the stored RF signal frame data group. For example, the RF signal frame data generated based on the time series, that is, the frame rate of the image from the phasing addition unit 18 is sequentially stored in the RF frame data selection unit 28, and the stored RF signal frame data (N) is first stored. At the same time, one RF signal frame data (X) is selected from the RF signal frame data group (N-1, N-2, N-3... NM) stored in the past in time. select. Here, N, M, and X are index numbers assigned to the RF signal frame data, and are natural numbers.

  Then, the displacement measuring unit 30 performs one-dimensional or two-dimensional correlation processing from the selected set of data, that is, the RF signal frame data (N) and the RF signal frame data (X), and corresponds to each point of the tomographic image. A one-dimensional or two-dimensional displacement distribution related to the displacement and movement vector in the living tissue, that is, the direction and magnitude of the displacement is obtained. Here, a block matching method is used to detect the movement vector. The block matching method divides an image into blocks of N × N pixels, for example, pays attention to the block in the region of interest, searches the previous frame for the block that is closest to the block of interest, and refers to this Then, predictive encoding, that is, processing for determining the sample value by the difference is performed.

  The elasticity information calculation unit 32 is a strain or elasticity of a living tissue corresponding to each point on the tomographic image from a measurement value output from the displacement measurement unit 30, for example, a movement vector, and a pressure value output from the pressure measurement unit 46. The modulus is calculated, and an elastic image signal, that is, elastic frame data is generated based on the strain and elastic modulus.

  At this time, the strain data is calculated by spatially differentiating the movement amount of the living tissue, for example, the displacement. The elastic modulus data is calculated by dividing the change in pressure by the change in strain. For example, assuming that the displacement measured by the displacement measuring unit 30 is L (X) and the pressure measured by the pressure measuring unit 46 is P (X), the strain ΔS (X) spatially differentiates L (X). Therefore, it can be calculated using the equation ΔS (X) = ΔL (X) / ΔX. Further, the Young's modulus Ym (X) of the elastic modulus data is calculated by the equation Ym = (ΔP (X)) / ΔS (X). Since the Young's modulus Ym determines the elastic modulus of the living tissue corresponding to each point in the tomographic image, two-dimensional elastic image data can be obtained continuously. The Young's modulus is a ratio of a simple tensile stress applied to the object and a strain generated in parallel with the tension.

  The elastic image construction unit 34 is configured to include a frame memory and an image processing unit, and secures elastic frame data output in time series from the elastic information calculation unit 32 in the frame memory. In contrast, image processing is performed.

The color scan converter 36 has a function of adding hue information to the elastic frame data from the elastic image construction unit 34. That is, the light is converted into the three primary colors of light, that is, red (R), green (G), and blue (B) based on the elastic frame data. For example, elastic data having a large strain is converted into a red code, and simultaneously elastic data having a small strain is converted into a blue code.
The switching addition unit 24 includes a frame memory, an image processing unit, and an image selection unit. The frame memory stores tomographic image data from the black and white scan converter 22, elastic image data from the color scan converter 36, and image data output from a biological simulated image control unit 44 described later. The image processing unit has a function of combining the tomographic image data and the elasticity image data secured in the frame memory by changing the combining ratio. The luminance information and hue information of each pixel of the composite image is obtained by adding the information of the black and white tomographic image and the color elastic image at the composite ratio. Further, the image selection unit selects an image to be displayed on the image display 26 from the tomographic image data, elasticity image data in the frame memory, synthesized image data of the image processing unit, and biological simulation image data.

  Then, the characteristic part of the ultrasound diagnosing device of this embodiment is demonstrated. The probe 12 is provided with a position information sensor 48 such as a magnetic sensor, an angular velocity sensor, or an infrared sensor. Also, a coordinate calculation unit 50 that calculates the three-dimensional coordinate position of the probe based on the output of the position information sensor 48, a tissue displacement detection unit 51 that detects that the tissue of the tomographic site of the subject is displaced, In addition, a mark creation unit 52 that generates an elastic image acquisition mark, an elastic mark, or the like based on the output of the coordinate calculation unit 50 and the output of the tissue displacement detection unit 51 is provided.

  Furthermore, a living body simulation image such as an illustration or a photograph simulating the subject is generated, and an elastic image acquisition mark generated by the mark creation unit 52 or an elastic image of the elasticity image is obtained at the position where the elasticity image on the living body simulation image is acquired. A living body simulated image constructing unit 54 that superimposes a simulated mark such as an elastic mark graded according to the hardness or softness of the tissue in the set region, and positional information of the tomographic site of the subject from which the elastic image was acquired, A memory 56 for storing information such as elasticity information is provided.

  Next, each embodiment of the tissue displacement detection unit 51 that detects that the tissue of the tomographic site of the subject is displaced will be described.

(First embodiment of tissue displacement detection)
The present embodiment is an example applied when an elastic image is generated by performing a compression / release operation on a subject using a probe. For example, when an elastic image is generated while repeatedly pressing / releasing to produce a slight strain change from a state in which the probe is applied to the subject and a certain stress is applied, the probe is attached to the probe. A signal detected by the position information sensor 48 is input to the coordinate calculation unit 50, and the coordinate calculation unit 50 performs division processing on the three-dimensional coordinate axes of the X axis, the Y axis, and the Z axis as shown in FIG. FIG. 2 is a diagram illustrating an example of changes in the coordinate position of the probe on the X-axis, Y-axis, and Z-axis coordinate axes of the three-dimensional coordinates of the probe output from the coordinate calculation unit 50.

  In the present embodiment, the coordinate 61 on the X axis and the coordinate 62 on the Y axis are substantially constant and not displaced, and the coordinate 63 on the Z axis is periodically displaced up and down. The tissue displacement detection unit 51 monitors the output from the coordinate calculation unit 50 and detects a periodic change in the coordinate position of the probe on the Z axis as in this embodiment, so that the probe is periodically It is determined that the subject is moving, that is, the subject is periodically pressed / released. Thereby, it can be automatically detected that the tissue of the tomographic site is displaced, and as a result, it can be detected that an appropriate elastic image has been acquired.

  In the present embodiment, for example, it is assumed that the probe is pressed / released in a substantially vertical direction with respect to the subject lying on the bed, and therefore the coordinates of the probe are periodically changed only in the Z-axis direction. It has fluctuated. Accordingly, depending on how the three coordinate axes are taken, the axes whose coordinates vary vary. For example, when a periodic change appears on only one of the three coordinate axes, a periodic change appears on any two axes, or a periodic change appears on all three axes. In short, it is possible to detect that an appropriate elasticity image has been acquired if a periodic change in coordinates on any one of the three coordinate axes corresponding to the displacement direction of the tissue is detected.

(Second embodiment of tissue displacement detection)
In this embodiment, when an elastic image is generated by performing a compression / release operation on a subject using a probe, or a pressure change is periodically applied to a tissue due to, for example, pulsation of the subject. This is an example applied to any of the cases where an elastic image is generated using.

  In this example, first, as shown on the left side of FIG. 3, tracking points 65 and 66 are set in the generated tomographic image. The tracking point may be set by, for example, displaying a tomographic image on the image display 26 and setting by the inspector via the interface unit 42, or by arbitrarily setting a plurality of tracking points on the tomographic image. You may comprise so that it may be set.

  Subsequently, the tracking points 65 and 66 are tracked using various methods such as a block matching method by the displacement measuring unit 30 or the like, for example, and a movement destination is obtained. The tissue displacement detector 51 measures the displacement of the distance in the direction corresponding to the tissue displacement direction between the tracking points 65 and 66. For example, in this embodiment, the case where the tissue is displaced in the vertical direction is taken as an example. In this case, the displacement measurement value 67 periodically changes as shown on the right side of FIG. The tissue displacement detector 51 can detect the displacement of the tissue at the tomographic site by detecting this periodic change.

  In this embodiment, two tracking points are set. However, the present invention is not limited to this, and three or more tracking points are set, and the displacement of the distance between these two arbitrary points is measured. Changes may be detected periodically. Further, instead of the distance between the tracking points, for example, one tracking point is set, and the periodic change in the direction corresponding to the displacement direction of the tissue at the position of the tracking point is detected, whereby the tissue of the tomographic site is detected. It is also possible to detect the displacement.

  This embodiment is particularly effective when it is easier to obtain a stable elastic image by using the movement of a tissue or body in which a change in internal pressure such as a heart or a blood vessel occurs. In other words, in this case, since the probe is not pressed from the body surface, the probe position is fixed and the probe position does not move, but it corresponds to the tissue displacement direction of the tracking point on the tomographic image. If the direction displacement is periodic, it is effective because it can be detected that the tissue of the tomographic site is displaced.

(Third embodiment of tissue displacement detection)
In this embodiment, when an elastic image is generated by performing a compression / release operation on a subject using a probe, or a pressure change is periodically applied to a tissue due to, for example, pulsation of the subject. This is an example applied to any of the cases where an elastic image is generated using.

  In the present embodiment, as shown on the left side of FIG. 4, the cross-correlation calculation of the pair of RF signal frame data 70 and 71 selected by the RF frame data selection unit 28 is performed by the displacement measurement unit 30 having a function as a correlation calculation unit. And input to the tissue displacement detector. The tissue displacement detector 51 detects the displacement of the tissue at the tomographic site based on the calculated correlation coefficient (correlation value). That is, the tissue displacement detection unit 51 monitors the correlation coefficient output from the correlation calculation means, and when the correlation coefficient becomes larger than a preset threshold as shown on the right side of FIG. Detect tissue displacement.

  In this embodiment, for example, when the probe is moved appropriately to obtain a tomographic image, the correlation coefficient of the pair of RF signal frame data is relatively low, but the probe When generating an elasticity image while performing compression / release operations on the subject, or when generating an elasticity image using pressure change due to the pulsation of the subject, the correlation value is relatively high. Is to be used. In other words, for example, when moderate compression is obtained or a moderate displacement can be detected, the degree of correlation between the RF signal frame data increases. By detecting this, the tissue at the tomographic site is displaced. And that the elasticity image is acquired.

  However, for example, when a tomographic site where no change in the internal pressure of the tissue occurs is imaged and the probe position is fixed, the pair of RF signal frame data substantially match and the correlation coefficient Shows an upper limit (for example, 1.0), and in such a case, it can be appropriately excluded from detection of tissue displacement.

(Fourth embodiment of tissue displacement detection)
In this embodiment, when an elastic image is generated by performing a compression / release operation on a subject using a probe, or a pressure change is periodically applied to a tissue due to, for example, pulsation of the subject. This is an example applied to any of the cases where an elastic image is generated using.

  When the pressure measurement unit 46 is provided as in the ultrasonic diagnostic apparatus of the present embodiment, the tissue displacement detection unit 51 takes in the measurement value of the pressure measurement unit 46 and measures the pressure value 73 as shown in FIG. The displacement of the tissue at the fault site is detected by the periodic change of.

  In this embodiment, when the compression / release operation is performed by the probe and when the change in the internal pressure of the subject is used, if the tissue of the tomographic site is displaced, This utilizes the fact that the internal pressure fluctuates and this is measured by the pressure measurement unit 46.

(Fifth embodiment of tissue displacement detection)
In the above embodiment, the displacement of the tissue is automatically detected by the ultrasonic diagnostic apparatus to detect the acquisition of the elastic image, but is not limited thereto. For example, in the fifth embodiment, the inspector manually acquires the elasticity image via the ultrasonic probe 12 or the interface unit 42 by referring to the image display 26 in real time while taking the elasticity image. Is an example of instructing. The tissue displacement detection unit 51 detects that an elastic image has been acquired by a signal input via the ultrasonic probe 12 or the interface unit 42.

  When detecting that an elastic image has been acquired by instructing acquisition of an elastic image using the ultrasonic probe 12, as shown in FIG. A button-shaped tissue displacement detection switch 74 that can be pushed down by the examiner is provided. When the examiner determines that an appropriate elastic image is generated by appropriate compression while referring to the image display 26, the examiner pushes down the tissue displacement detection switch 74. The tissue displacement detection unit 51 receives a signal resulting from this push-down operation, and detects that the tissue displacement and elasticity image of the tomographic site have been acquired. The tissue displacement detection switch is not limited to the button switch, but may be any switch that can be arbitrarily operated by the examiner.

  Further, for example, a voice receiver such as a microphone is provided as the interface unit 42, and it is possible to detect that an elastic image has been acquired by instructing acquisition of the elastic image using this. That is, an audio signal of a predetermined specific phrase is recorded in a memory, and the tissue displacement detection unit 51 uses a pattern recognition between the audio signal received by the microphone and the recorded audio signal to record the audio signal. It is detected that the displacement of the tissue at the tomographic site and the detected elastic image are acquired when the corresponding audio signal, such as matching or similar to the received audio signal, is received by the microphone.

  In this case, in order to prevent an unnecessary elastic image from being acquired due to erroneous voice recognition, the fact that the elastic image is acquired by the voice recognition is displayed on the image display 26 and whether or not to execute is determined. The examiner may be prompted to make a decision by voice or manual operation.

  The tissue displacement detector 51 detects the displacement of the tissue at the tomographic site by any one of the modes as described above or a combination thereof. After the displacement of the tissue at the tomographic site is detected, the living body simulated image and the simulation superimposed on the living body simulated image are displayed on the image display 26 by the mark creating unit 52, the living body simulated image forming unit 54, and the like that function as a simulated image display unit. A mark is displayed.

  Hereinafter, an embodiment of a display mode of a living body simulation image displayed on the image display 26 by the mark creation unit 52, the living body simulation image construction unit 54, and the like, and a simulation mark superimposed thereon will be described. In the following description, only the display of a living body simulation image and a simulation mark superimposed on the living body simulation image will be described. However, it can be displayed on the image display 26 in combination with a tomographic image, an elasticity image, or the like as appropriate.

(First example of display)
The present embodiment is an example in which an elastic image acquisition mark indicating a tomographic site from which an elastic image has been acquired is superimposed and displayed on a living body simulation image. In the present embodiment and the following embodiments, a case where an image simulating the breast of a subject is applied as a living body simulation image is shown.

  First, the overall operation of the ultrasonic diagnostic apparatus and the operation of the characteristic part will be described with reference to FIG. As shown in FIG. 7, in a normal inspection routine, ultrasonic waves are transmitted and received while performing a probe operation (S75), and processing of ultrasonic images such as tomographic images and elastic images is performed as described above. (S76) These images are displayed (S77).

  On the other hand, coordinate calculation is performed by the coordinate calculation unit 50 (S78), and positional information of the tomographic part of the subject is acquired, and a tissue change of the tomographic part is detected by the tissue displacement detection unit 51 (S79). Are input to the mark creation unit 52. Then, the mark creation unit 52 generates an elastic image acquisition mark based on the output from the coordinate calculation unit 50 when the tissue displacement is detected by the tissue displacement detection unit 51, that is, the position information of the tomographic site of the subject. (S80).

  The biological simulated image constructing unit 54 is obtained in the process of obtaining the elastic image acquisition mark generated by the mark creating unit 52 and the tomographic position information and the elastic image of the subject from which the elastic image stored in the memory 56 is acquired. Using the obtained information such as the output transition of the pressure measuring unit 46 as appropriate, a living body simulation image is constructed by superimposing an elastic image acquisition mark at a corresponding position on the living body simulation image (S81). As a result, the ultrasound image and the living body simulation image on which the simulation mark is superimposed are appropriately combined and displayed on the image display.

  In the present embodiment, when an elastic image is acquired by performing ultrasonic imaging, an elastic image acquisition mark 86 indicating a tomographic part from which the elastic image has been acquired at a corresponding position on the living body simulation image 85 as shown in FIG. Are superimposed and displayed. As shown in the figure, the elastic image acquisition mark 86 includes information on the scanning position and orientation of the ultrasonic probe.

  By displaying this in real time during ultrasonic imaging, an inspector who performs ultrasonic imaging can visually check at which position of the subject the elastic image has been acquired by referring to the living body simulated image. . In addition, if the living body simulation image 85 on which the elastic image acquisition mark 86 is superimposed is stored in the memory, a diagnostician or the like who makes a diagnosis with reference to the stored image visually refers to the living body simulation image. It can be confirmed at which position of the specimen the elasticity image was acquired.

  Further, for example, when the inspector acquires elastic images as shown in Frames A to F in FIG. 8, the elastic image acquisition marks 86 may be displayed one by one in real time, as shown on the right side of the figure. Each time an elastic image is acquired, the mark may be sequentially superimposed and displayed on the biological simulation image while the elastic image acquisition mark 86 superimposed in the past is left on the biological simulation image. According to this, since the part where the elasticity image of the subject is acquired can be grasped at a glance, it is possible to prevent the image from being missed or to avoid wasteful imaging of the same part. .

  The coordinate calculation unit 50 aligns the coordinate system of the three-dimensional coordinates detected by the position information sensor with the coordinate system of the subject while ultrasonically imaging a specific part such as the nipple of the subject. Thereby, the ultrasonic imaging position on the living body simulation image can be specified.

(Second example of display)
In the present embodiment, information such as pressure measured by the pressure measurement unit 46 in the process of acquiring the elasticity image is displayed via the elasticity image acquisition mark superimposed on the living body simulation image. In this embodiment, the elasticity image acquisition mark 86 is superimposed on the biological simulation image 85, and the output transition of the pressure detected by the pressure measurement unit 46 when the elasticity image corresponding to each elasticity image acquisition mark is acquired. It is assumed that each elastic image acquisition mark 86 is recorded in the memory in association with each other.

  FIG. 9 shows a state in which the examiner refers to the living body simulated image generated in the first embodiment of the display during the ultrasonic imaging, or is examined by the examiner after being recorded in the memory. It is assumed that For example, when a diagnostician or the like selects an arbitrary elasticity image acquisition mark via an interface such as a mouse, keyboard, trackball, or screen touch sensor, a graph of the output transition of the pressure sensor associated with the selected mark, pressure A pressure state display 87 including the average amplitude of the pressure obtained from the output transition of the sensor and the average value of the pressure obtained from the output transition of the pressure sensor is made.

  Regarding the acquisition of an elastic image, for example, when pressing with a probe, it is very important whether the compression is performed appropriately. If the degree of compression is different, a desired elastic image can be acquired. It becomes difficult. In this regard, according to the present embodiment, for example, if the diagnostician selects an elastic image acquisition mark of interest while referring to the biological simulated image once recorded in the memory, an elastic image is acquired at the tomographic location. It is possible to display the pressure conditions at the time. Therefore, it is possible to operate the probe so as to satisfy the same compression condition while referring to this. In this way, by providing multifaceted information to the diagnostician, the diagnostician can obtain an elastic image again with good reproducibility with reference to the displayed pressure conditions and the like. It may be used effectively.

  The selection of the elastic image acquisition mark is not limited to the input from the interface, but may be automatically set so as to be switched every set time. In addition to the information shown in this embodiment, the elastic image Information obtained in the process of obtaining the information may be appropriately stored in a memory and displayed according to the selection of the mark. Further, a plurality of elastic image acquisition marks may be selected and a plurality of detailed information may be displayed, or graphs or the like may be superimposed and displayed.

(Third embodiment of display)
The present embodiment is an example in which an elastic mark representing the hardness or softness of a set region in a tomographic site from which an elastic image is acquired, that is, a tissue (tumor) of interest, is superimposed on a biological simulated image.

  First, the overall operation of the ultrasonic diagnostic apparatus and the operation of the characteristic part will be described with reference to FIG. As shown in FIG. 10, in a normal inspection routine, ultrasonic waves are transmitted and received while performing a probe operation (S90), and processing of ultrasonic images such as tomographic images and elastic images is performed as described above. (S91), these images are displayed (S92).

  On the other hand, coordinate calculation is performed by the coordinate calculation unit 50 (S93), position information of the tomographic part of the subject is acquired, and tissue change of the tomographic part is detected by the tissue displacement detection unit 51 (S94). Are input to the mark creation unit 52. Further, information of tomographic images and elasticity images obtained by ultrasonic imaging is input to the mark creating unit 52. Then, the output from the coordinate calculation unit 50 when the displacement of the tissue is detected by the tissue displacement detection unit 51 by the mark creation unit 52, that is, the position information of the tomographic part of the subject and the region set in the elastic image Based on the elasticity information representing the hardness or softness of the tissue of interest, a simulated mark such as an elastic mark is generated (S95).

  The living body simulated image construction unit 54 includes the elasticity mark generated by the mark creation unit 52, the tomographic position information of the subject from which the elasticity image stored in the memory 56 is acquired, and the elasticity information of the tissue in the elastic image setting region. Using the information such as the output transition of the pressure measurement unit 46 obtained in the process of obtaining the elasticity image, and the like, the simulated mark is superimposed on the corresponding position on the simulated biological image to construct the simulated biological image (S96). ). As a result, the ultrasound image and the living body simulation image on which the simulation mark is superimposed are appropriately combined and displayed on the image display.

  Thereby, a display as shown in FIG. 11 is displayed. That is, when an elastic image is acquired, a circular elastic mark 101 gradated according to the hardness or softness of the tissue (tumor) in the setting area of the elastic image is superimposed on the corresponding position on the living body simulation image 85. Displayed. In addition to this, an elastic scale bar 102 is displayed that associates the tone gradation and the degree of tissue hardness or softness.

  As in the first example of display, when an elastic image is acquired, the elastic marks 101 may be displayed one by one in real time, or the elastic marks 101 superimposed in the past on the living body simulated image are left. Alternatively, each time an elastic image is acquired, the marks may be sequentially superimposed and displayed on the biological simulated image. In this embodiment, an example of hue gradation is given. However, for example, the hardness or softness of the tissue may be displayed with gradation according to a numerical value or luminance.

  In the present embodiment, an example in which a simulation mark is superimposed and displayed on a living body simulation image has been shown. However, the simulation mark may be displayed in association with a tomographic image or a part of an elastic image.

  Next, generation of the elastic mark 101 will be described in more detail with reference to FIG. The elasticity mark 101 represents not the elasticity information of the entire acquired elasticity image but the elasticity information of the region of interest where the elasticity image is set, that is, the tissue of interest such as a tumor. Therefore, it is necessary to set a region of interest tissue from the elastic image.

  In this regard, as shown in FIG. 12, it is utilized that the tissue of interest such as a tumor shows a low echo (low reflection level) on the black and white tomographic image 110. That is, first, binarization processing is performed on the black and white tomographic image, and the position or distribution of the tumor is detected by setting a low echo area as a mask area.

  Then, in the elastic image 111, the tissue 112 in the mask region is cut out, and the elasticity information of the cut out tissue is averaged to create the elastic mark 101. In addition, the elastic mark need not be circular, and the shape can also be expressed and displayed using tumor distribution information.

  By performing such display, it is possible to easily grasp the elasticity information of the tissue of interest in the set region in the tomographic site of the elasticity image through the living body simulated image.

  In addition, for example, if the examiner has taken a whole elasticity image on the subject and a living body simulated image on which the elasticity mark is superimposed is recorded, the subject can be referred to when the diagnostician refers to this. It is possible to easily determine which part of the eye should be examined in detail. In other words, since the elastic mark is represented as a simple mark gradationized by hue or a numerical value, for example, it is relatively hard on the living body simulated image and a place where a lesion tissue may exist is seen at a glance. Can be grasped. Then, if necessary, it is possible to carry out a detailed examination by, for example, performing ultrasound imaging again, and determine a diagnosis and a treatment policy.

(Fourth example of display)
The present embodiment is an example in which an elastic image that is a basis for generating the elastic mark is displayed via the elastic mark superimposed on the living body simulation image. In the present embodiment, it is assumed that the elasticity mark 101 is superimposed on the biological simulation image 85 and that the elasticity image corresponding to each elasticity mark is recorded in the memory in association with each elasticity mark 101.

  FIG. 13 shows a state in which the examiner is referring to the simulated biological image generated in the third embodiment of the display during the ultrasonic imaging, or after being inspected and recorded in the memory, the examiner refers to the state. It is assumed that For example, when a diagnostician or the like selects an arbitrary elasticity image acquisition mark via an interface such as a mouse, keyboard, trackball, or screen touch sensor, the elasticity image associated with the selected mark is called from the memory and elastic. An image display 120 is made.

  According to the present embodiment, for example, after the diagnostician is once recorded in the memory, if the elastic image acquisition mark of interest is selected while being displayed and referring to the living body simulation image, the elastic image at the tomographic point is referred to. can do. In this way, by providing information to the diagnostician from multiple angles, the diagnostician determines the overall tumor status of the subject while referring to the displayed living body simulation image and elasticity mark. On the other hand, it is possible to make a diagnosis or determine a treatment policy by calling an elastic image and referring to a point of interest in detail.

  The calling of the elastic image of the present embodiment and the calling of the pressure state shown in the second embodiment of the display may be appropriately combined and displayed.

(Fifth embodiment of display)
The present embodiment is an example in which elastic marks are displayed in a gradation on a biological simulation image. That is, when the elastic mark is displayed, if it is detected at two or more locations, there is a high possibility that the objects inside are continuous. Therefore, as shown in FIG. 14, it is possible to express it with gradation by using the information on the degree of elasticity between the two points and the distance between them.

  For example, when the examiner conducts an examination and determines that the subject is a continuous object (tumor), the continuity can be displayed by representing the two points with gradation. As a result, it can be reflected in the chart information without repeating the compression, which is effective in shortening the examination time.

(Sixth example of display)
The present embodiment is an example in which only the elastic marks that are gradations within a threshold value range that is greater than or equal to a preset threshold value, or within a threshold value range are displayed. That is, for example, as shown in FIG. 15, by using an elastic scale bar 102 or the like, a threshold value is set in advance, or an examination person or a diagnosis person can arbitrarily set and adjust the examination. Only information necessary for the person / diagnostic can be displayed on the living body simulated image. It is also possible to automatically set this threshold value for each examination site.

According to this, for example, only an elastic mark that is harder than a predetermined threshold value, that is, a lesion may be necessary and a detailed examination is necessary, can be displayed. With reference to only necessary information, diagnosis and treatment policy can be determined. Since the display of the living body simulated image and the elasticity mark simply provides information such as the tissue elasticity of the subject to the examiner / diagnostic, it may not be practical even if there is too much information. In this case, the present embodiment is effective.
(Seventh example of display)
In this embodiment, an elastic mark is displayed on a living body simulation image generated in three dimensions. That is, as shown in FIG. 16A, the position information of the tomographic part of the subject when the elastic image is acquired and the surface of the tomographic part of the subject on the biological simulated image 85 generated in three dimensions. The elastic mark 101 can be superimposed and displayed in consideration of the depth information from.

  In addition, as shown in FIG. 16B, the compression mark 150 indicating the position of the contact surface of the ultrasonic probe with the subject when the elastic image is acquired is superimposed and displayed. Can do.

  According to this, it becomes possible to leave the depth information from the ultrasonic transmission / reception unit in the medical chart as illustration information. For example, in cases where cancer invasion is seen in the depth direction, which is difficult with two-dimensional information, it can be expressed in three dimensions as an elastic mark of a tumor, which is effective in that it can be easily grasped after examination.

  Further, for example, in the diagnosis of the visceral system, it may be important in the diagnosis whether the position to which the elastic mark is attached is an image obtained from which compression position. In this case, the compression mark 150 is provided on the body surface, and the elastic mark 101 is provided on the inside and displayed at the same time, whereby the relationship between the compression location and the image can be easily linked.

  Even if it is a three-dimensional living body simulated illustration, if there are many examination positions, it will be messy and difficult to see as a display, so the compression position and tumor position selected in the two-dimensional living body simulated image These pairs may be displayed on the three-dimensional living body simulated image, or the combination may be expressed using color coding, diagonal lines, or the like.

(Eighth embodiment of display)
This embodiment is an example in which a blood flow mark is superimposed and displayed on a living body simulation image in addition to a simulation mark, and blood flow information is obtained based on a reflected echo signal measured by an ultrasonic probe. It is presupposed that blood flow mark generation means for generating a blood flow mark that is graded according to the blood flow velocity of the tomographic site of the subject is provided.

  In other words, the speed or abundance of blood flow can be detected by a method using a known Doppler effect, and a blood flow mark gradated according to the detection result can be generated. Then, as shown in FIG. 17, the blood flow mark 160 can be made smaller than the elastic mark 101 and displayed on the elastic mark 101 together. In addition, a blood flow scale bar 161 indicating the speed of blood flow or the degree of abundance can be displayed.

  For example, malignant tumors tend to absorb blood from surrounding tissues and grow. Therefore, it is considered that blood flow information and elasticity information can be simultaneously displayed on a living body simulated image and used as medical chart information to improve diagnosis accuracy and efficiency.

  Note that the blood flow mark 160 can be easily recognized by distinguishing the blood flow mark 160, such as a star, and the elastic mark 101, as a circle. Visibility can be improved by distinguishing between blood flow marks such as black and white gradation and elastic marks such as color gradation. Further, only the portion where the blood flow mark and the elasticity mark overlap may be displayed on the living body illustration.

(Ninth embodiment of display)
In the present embodiment, when a reexamination is performed on a subject that has been subjected to ultrasonic imaging in the past and an elastic image is acquired, the location where the elastic image has been acquired in the past (the elasticity information is This is an example of informing the recorded position).

  That is, first, an ultrasonic examination is performed after performing calibration and positioning with reference to a specific position of the subject such as a nipple. Then, as shown in FIG. 18, when the ultrasonic probe is moved to a location where an elastic image has been acquired in the past (when the position of the elastic mark 101 and the probe mark 170 indicating the probe position overlap each other). ), “PUSH” or the like can be displayed on the image display 26 to prompt the examiner to perform an elastic image acquisition operation. At that time, elastic images acquired in the past may be displayed together.

  Thus, by presenting the location where the elastic image should be acquired to the inspector, the burden on the inspector can be reduced and the efficiency of the inspection can be increased. In this case, the reproducibility can be improved by displaying the pressure condition when the elastic image is acquired.

  As mentioned above, although the embodiment of the ultrasonic diagnostic apparatus of the present invention has been described, the present invention is not limited to the breast, and can be applied to places where ultrasonic image diagnosis is possible, such as the thyroid gland, liver, and prostate.

1 is a block diagram illustrating an overall configuration of an ultrasonic diagnostic apparatus according to an embodiment. It is a figure for demonstrating 1st Example of a tissue displacement detection. It is a figure for demonstrating 2nd Example of a tissue displacement detection. It is a figure for demonstrating 3rd Example of a tissue displacement detection. It is a figure for demonstrating the 4th Example of a tissue displacement detection. It is a figure for demonstrating the 5th Example of a tissue displacement detection. It is a flowchart of the whole operation | movement of an ultrasonic diagnosing device, and the operation | movement which produces | generates an elasticity image acquisition mark and it superimposes on a biological simulation image. It is a figure for demonstrating the 1st Example of a display. It is a figure for demonstrating the 2nd Example of a display. It is a flowchart of the whole operation | movement of an ultrasonic diagnosing device, and the operation | movement which produces | generates an elastic mark and is superimposed and displayed on a biological simulation image. It is a figure for demonstrating the 3rd Example of a display. It is a figure for demonstrating in detail the production | generation method of an elastic mark. It is a figure for demonstrating the 4th Example of a display. It is a figure for demonstrating the 5th Example of a display. It is a figure for demonstrating the 6th Example of a display. It is a figure for demonstrating the 7th Example of a display. It is a figure for demonstrating the 8th Example of a display. It is a figure for demonstrating the 9th Example of a display.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Ultrasonic diagnostic apparatus 10 Subject 12 Ultrasonic probe 18 Phase adjustment addition part 20 Tomographic image structure part 28 RF frame data selection part 30 Displacement measurement part 32 Elastic information calculation part 34 Elastic image structure part 42 Interface part 48 Position information Sensor 50 Coordinate operation unit 51 Tissue displacement detection unit 52 Mark creation unit 54 Living body simulated image construction unit 56 Memory 65, 66 Tracking point 67 Displacement measurement value 70, 71 RF signal frame data 73 Pressure measurement value 74 Tissue displacement detection switch 85 Living body simulated image 86 Elastic image acquisition mark 87 Pressure state display 101 Elastic mark 102 Elastic scale bar 150 Compression mark 160 Blood flow mark 161 Blood flow scale bar

Claims (10)

An ultrasonic probe that transmits and receives ultrasonic waves to and from the subject, and represents the hardness or softness of the tissue at the tomographic site of the subject based on the reflected echo signal measured by the ultrasonic probe Elastic image construction means for generating an elastic image, biological simulation image generation means for generating a biological simulation image simulating the subject, and three-dimensional coordinates of the ultrasonic probe attached to the ultrasonic probe A position sensor for detecting a position and orientation, a tomographic part detection means for detecting positional information of a tomographic part of the subject based on an output from the position sensor, and a tissue of the tomographic part of the subject are displaced A tissue displacement detecting means for detecting this ,
The biological simulated image generation means superimposes an elastic image acquisition mark on a corresponding position on the biological simulated image based on positional information of a tomographic site of the subject when a displacement of the tissue is detected. an ultrasonic diagnostic apparatus to be. The ultrasonic diagnostic apparatus according to claim 1,
Display means for displaying the living body simulated image on which the elastic image acquisition mark is superimposed, or the living body simulated image on which the elastic image acquisition mark is superimposed on the elastic image generated when displacement of the tissue is detected An ultrasonic diagnostic apparatus comprising: a means for associating and recording in a memory. Phasing and adding means for generating RF signal frame data of the tomographic part of the subject based on the reflected echo signal measured by the ultrasonic probe;
The ultrasonic diagnostic apparatus according to claim 1, wherein the elastic image constructing unit generates an elastic image representing the hardness or softness of the tissue of the tomographic site based on the RF signal frame data. The tissue displacement detection means includes at least one coordinate axis corresponding to the displacement direction of the tissue among the three-dimensional coordinates of the ultrasound probe detected by a position sensor attached to the ultrasound probe. The ultrasonic diagnostic apparatus according to claim 1, wherein a displacement of the tissue of the tomographic site is detected by a periodic change in coordinates. Based on the RF signal frame data of the tomographic part of the subject, tomographic image forming means for generating a tomographic image of the tomographic part of the subject, means for setting a tracking point in the tomographic image, and the position of the tracking point And means for detecting
The tissue displacement detecting unit, according to any one of claims 1 to 3 detects the displacement of the tissue of the tomographic site by the periodic direction corresponding to the displacement direction of the tissue of the position of the tracking point variation the ultrasonic diagnostic apparatus. A tomographic image forming means for generating a tomographic image of the tomographic part of the subject based on the RF signal frame data of the tomographic part of the subject; a means for setting a plurality of tracking points in the tomographic image; Means for detecting the position of the tracking point,
The tissue displacement detection means measures a displacement of a distance in a direction corresponding to the tissue displacement direction between the plurality of tracking points, and detects a tissue displacement of the tomographic site by a periodic change of the measured value of the displacement. The ultrasonic diagnostic apparatus of any one of Claims 1 thru | or 3 to detect. Correlation calculating means for performing a cross-correlation calculation of the RF signal frame data of the tomographic part of the subject ,
The tissue displacement detecting unit, when the correlation coefficient obtained by the correlation calculation means is larger than a predetermined threshold value, any one of claims 1 to 3 for detecting a displacement of the tomographic site tissue 1 The ultrasonic diagnostic apparatus according to item . A pressure sensor is provided on the contact surface of the ultrasonic probe with the subject,
4. The ultrasonic diagnostic apparatus according to claim 1, wherein the tissue displacement detection unit detects a tissue displacement of the tomographic site based on a periodic change in a measurement value of the pressure sensor. 5. The ultrasonic probe is provided with a tissue displacement detection switch that can be operated by an examiner,
4. The ultrasonic diagnostic apparatus according to claim 1, wherein the tissue displacement detection unit detects a tissue displacement of the tomographic site when the tissue displacement detection switch is operated by the examiner. 5. Equipped with a microphone,
4. The tissue displacement detection unit according to claim 1, wherein the tissue displacement detection unit detects a tissue displacement of the tomographic site when an audio signal corresponding to a predetermined audio signal is received by the microphone . 5. Ultrasonic diagnostic equipment.

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