JP5154554B2 - 非線形イメージングのためのパルスインバージョンシーケンス - Google Patents
非線形イメージングのためのパルスインバージョンシーケンス Download PDFInfo
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- JP5154554B2 JP5154554B2 JP2009523047A JP2009523047A JP5154554B2 JP 5154554 B2 JP5154554 B2 JP 5154554B2 JP 2009523047 A JP2009523047 A JP 2009523047A JP 2009523047 A JP2009523047 A JP 2009523047A JP 5154554 B2 JP5154554 B2 JP 5154554B2
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Images
Classifications
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- G—PHYSICS
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- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
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- G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
- G01S7/52023—Details of receivers
- G01S7/52036—Details of receivers using analysis of echo signal for target characterisation
- G01S7/52038—Details of receivers using analysis of echo signal for target characterisation involving non-linear properties of the propagation medium or of the reflective target
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
- A61B8/4444—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
- A61B8/4461—Features of the scanning mechanism, e.g. for moving the transducer within the housing of the probe
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
- A61B8/4483—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer
- A61B8/4488—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer the transducer being a phased array
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/48—Diagnostic techniques
- A61B8/481—Diagnostic techniques involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/48—Diagnostic techniques
- A61B8/483—Diagnostic techniques involving the acquisition of a 3D volume of data
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
- G01S15/88—Sonar systems specially adapted for specific applications
- G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
- G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
- G01S15/895—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques characterised by the transmitted frequency spectrum
- G01S15/8956—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques characterised by the transmitted frequency spectrum using frequencies at or above 20 MHz
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
- G01S15/88—Sonar systems specially adapted for specific applications
- G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
- G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
- G01S15/8959—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using coded signals for correlation purposes
- G01S15/8963—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using coded signals for correlation purposes using pulse inversion
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
- G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
- G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
- G01S7/52023—Details of receivers
- G01S7/52036—Details of receivers using analysis of echo signal for target characterisation
- G01S7/52038—Details of receivers using analysis of echo signal for target characterisation involving non-linear properties of the propagation medium or of the reflective target
- G01S7/52039—Details of receivers using analysis of echo signal for target characterisation involving non-linear properties of the propagation medium or of the reflective target exploiting the non-linear response of a contrast enhancer, e.g. a contrast agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
- G01S15/88—Sonar systems specially adapted for specific applications
- G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
- G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
- G01S15/8959—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using coded signals for correlation purposes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
- G01S15/88—Sonar systems specially adapted for specific applications
- G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
- G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
- G01S15/8993—Three dimensional imaging systems
Description
これらイメージング方式には、基本周波数抑制不良に起因して欠点を有する。
組織模倣媒体中の非線形高周波ビームを計算し、重み付けPI信号処理の効率に対する変換器回転の影響を吟味するシミュレーションツールが開発された。この例では、20MHzガウスパルス(2MPa、50%帯域幅)を散乱及び減衰(1.0dB×cm-1×MHz-1)媒体中に伝搬させ、その結果、40MHzで2次高調波信号が生じた。基本周波数抑制を互いに異なるPIシーケンスについて或る範囲のパルス間角度(0.15°〜1.5°)について吟味した。0.15°のパルス間角度では、1回転につき2,400本の線密度を用いるプロトタイプシステムで実施された初期ハーモニックIVUS実験で用いられた角度に一致している。1.5°のパルス間角度では、1回転当たり256本の線密度の角度に一致している。
〔表1〕
シーケンス 18〜22MHzの平均減少 追加の減少対基本PI
〔1 1〕(基本PI) 28.2dB 0dB
〔1 2 1〕 34.8dB 6.6dB
〔1 2 2 2 2 2 1 〕 38.8dB 10.6dB
〔1 3 4 4 4 3 1 〕 38.5dB 10.3dB
〔表2〕
シーケンス 18〜22MHzの平均減少 追加の減少対基本PI
〔1 1〕(基本PI) 23.0dB 0dB
〔1 2 1〕 32.3dB 9.3dB
〔1 2 2 2 2 2 1 〕 35.9dB 12.9dB
〔1 3 4 4 4 3 1 〕 36.5dB 13.5dB
〔1〕ボウカズ・エイ(Bouakaz A),デ・ジョン・エヌ(de Jong N)著,「ネイティブ・ティッシュー・イメージング・アット・スーパーハーモニック・フリクエンシーズ(Native tissue imaging at superharmonic frequencies)」,IEEEトランズアクション・ウルトラソニック・フェロエレクトロニック・フリクエンス・コントロール(IEEE Trans Ultrason Ferroelec Freq Control),2003年,第50巻,第5号,p.496〜506
〔2〕ホープ・シンプソン・デー・エイチ・(Hope Simpson D H),チン・シー・ティー(Chin CT),バーンズ・ピイ・エヌ(Burns PN)著,「パルス・インバージョン・ドップラー:ア・ニュー・メソッド・フォー・ディテクティング・ノンリニアー・エコーズ・フロム・マイクロバブル・コントラスト・エージェント(Pulse inversion doppler: A new method for detecting nonlinear echoes from microbubble contrast agents)」,IEEEトランズアクション・ウルトラソニック・フェロエレクトロニック・フリクエンス・コントロール(IEEE Trans Ultrason Ferroelec Freq Control),1999年,第46巻,第2号,p.372〜382
〔3〕ゴーツ・ディー・イー(Goertz DE),フリジリンク・エム・イー(Frijlink ME),デ・ジョン・エヌ(de Jong N),バン・ダー・スティーン・エイ・エフ・ダブリュー(van der Steen AFW)著,「ノンリニアー・イントラバスキュラー・ウルトラサウンド・コントラスト・イメージング(Nonlinear Intravascular Ultrasound Contrast Imaging)」、ウルトラサウンド・イン・メディスン・アンド・バイオロジー(Ultrasound in Med & Biol),2006年,第32巻,第4号,p.491〜502
Claims (18)
- nは、3以上である、請求項1記載の装置。
- a,b,cは、それぞれ、1、2、1に等しい、請求項1記載の装置。
- 前記受け取ったエコー信号は、高調波応答を含む、請求項1記載の装置。
- 前記受け取ったエコー信号は、低調波応答を含む、請求項1記載の装置。
- 前記受け取ったエコー信号は、超高調波応答(ultraharmonic response)を含む、請求項1記載の装置。
- 前記超音波変換器は、カテーテル利用型超音波変換器である、請求項1記載の装置。
- 関心のある部位を画像化するように、前記変換器を機械的に走査するための手段を更に有する、請求項7記載の装置。
- 前記励起パルスは、15MHz以上の搬送周波数で送信される、請求項1記載の装置。
- 前記励起パルスは、20MHz以上の搬送周波数で送信される、請求項1記載の装置。
- 前記変換器を機械的に走査する手段は、前記変換器を回転させる手段を有する、請求項8記載の装置。
- 前記変換器は、変換器アレイを有し、更に、前記装置は、
前記変換器アレイを機械的に動かす手段と、
前記変換器アレイを動かしているときに前記変換器アレイにより複数の2次元画像を得る手段と、
3次元画像を形成するように、前記複数の2次元画像を組み合わせるための手段と、を更に有する、請求項1記載の装置。 - 前記変換器は単一変換器要素を有し、更に、前記装置は、
前記単一変換器要素を機械的に動かす手段と、
前記単一変換器要素を動かしているときに前記単一変換器要素により複数の2次元画像を得る手段と、
3次元画像を形成するように、前記複数の2次元画像を組み合わせるための手段と、を更に有する、請求項1記載の装置。 - 気泡破壊イメージング技術を用いるように構成された、請求項1記載の装置。
- 2周波数イメージング技術を用いるように構成された、請求項1記載の装置。
- 反復率イメージング技術を用いる用に構成された、請求項1記載の装置。
- 気泡記憶イメージング技術を用いるように構成された、請求項1記載の装置。
- 気泡破壊イメージング技術、2周波数イメージング技術、反復率イメージング技術、気泡記憶イメージング技術、又はこれらの組合せを用いて画像化するように構成された、請求項1記載の装置。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82110606P | 2006-08-01 | 2006-08-01 | |
US60/821,106 | 2006-08-01 | ||
US82486206P | 2006-09-07 | 2006-09-07 | |
US60/824,862 | 2006-09-07 | ||
PCT/US2007/074996 WO2008016992A1 (en) | 2006-08-01 | 2007-08-01 | Pulse inversion sequences for nonlinear imaging |
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JP2009545406A JP2009545406A (ja) | 2009-12-24 |
JP2009545406A5 JP2009545406A5 (ja) | 2010-09-16 |
JP5154554B2 true JP5154554B2 (ja) | 2013-02-27 |
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Country Status (5)
Country | Link |
---|---|
US (1) | US7967753B2 (ja) |
EP (1) | EP2076179B1 (ja) |
JP (1) | JP5154554B2 (ja) |
CA (1) | CA2659645C (ja) |
WO (1) | WO2008016992A1 (ja) |
Families Citing this family (13)
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JP5322522B2 (ja) * | 2008-07-11 | 2013-10-23 | 株式会社東芝 | 超音波診断装置 |
JP2010063493A (ja) * | 2008-09-08 | 2010-03-25 | Aloka Co Ltd | 超音波診断装置 |
EP2488107B1 (en) * | 2009-10-12 | 2017-03-08 | Acist Medical Systems, Inc. | Intravascular ultrasound system for co-registered imaging |
US9216008B2 (en) | 2012-01-30 | 2015-12-22 | Technion Research & Development Foundation Limited | Quantitative assessment of neovascularization |
US9693754B2 (en) | 2013-05-15 | 2017-07-04 | Acist Medical Systems, Inc. | Imaging processing systems and methods |
US9704240B2 (en) | 2013-10-07 | 2017-07-11 | Acist Medical Systems, Inc. | Signal processing for intravascular imaging |
BR112016017236B1 (pt) | 2014-01-23 | 2022-09-27 | Supersonic Imagine | Método para determinar uma característica física numa localização pontual dentro de um meio, um método para determinar uma imagem de um meio e aparelho que implementa os referidos métodos |
US10653393B2 (en) | 2015-10-08 | 2020-05-19 | Acist Medical Systems, Inc. | Intravascular ultrasound imaging with frequency selective imaging methods and systems |
US10909661B2 (en) | 2015-10-08 | 2021-02-02 | Acist Medical Systems, Inc. | Systems and methods to reduce near-field artifacts |
US11369337B2 (en) | 2015-12-11 | 2022-06-28 | Acist Medical Systems, Inc. | Detection of disturbed blood flow |
WO2017117389A1 (en) | 2015-12-31 | 2017-07-06 | Acist Medical Systems, Inc. | Semi-automated image segmentation system and method |
EP3459048B1 (en) | 2016-05-16 | 2023-05-03 | Acist Medical Systems, Inc. | Motion-based image segmentation systems and methods |
US11024034B2 (en) | 2019-07-02 | 2021-06-01 | Acist Medical Systems, Inc. | Image segmentation confidence determination |
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US7967753B2 (en) | 2011-06-28 |
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