JP5133069B2 - 短パルス特性を有するレーザシステム及びその使用方法 - Google Patents
短パルス特性を有するレーザシステム及びその使用方法 Download PDFInfo
- Publication number
- JP5133069B2 JP5133069B2 JP2007557145A JP2007557145A JP5133069B2 JP 5133069 B2 JP5133069 B2 JP 5133069B2 JP 2007557145 A JP2007557145 A JP 2007557145A JP 2007557145 A JP2007557145 A JP 2007557145A JP 5133069 B2 JP5133069 B2 JP 5133069B2
- Authority
- JP
- Japan
- Prior art keywords
- pulse
- laser
- pulsed output
- pulse train
- time
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 title claims description 21
- 230000000694 effects Effects 0.000 claims description 17
- 239000007787 solid Substances 0.000 claims description 13
- 210000001519 tissue Anatomy 0.000 claims description 13
- 230000005284 excitation Effects 0.000 claims description 9
- 230000002207 retinal effect Effects 0.000 claims description 8
- 239000000654 additive Substances 0.000 claims description 5
- 230000000996 additive effect Effects 0.000 claims description 5
- 229910009372 YVO4 Inorganic materials 0.000 claims description 4
- 210000000981 epithelium Anatomy 0.000 claims description 3
- 238000012544 monitoring process Methods 0.000 claims description 2
- 230000003252 repetitive effect Effects 0.000 claims description 2
- 238000011282 treatment Methods 0.000 description 19
- 230000000649 photocoagulation Effects 0.000 description 15
- 210000003583 retinal pigment epithelium Anatomy 0.000 description 10
- 238000002560 therapeutic procedure Methods 0.000 description 6
- 210000003161 choroid Anatomy 0.000 description 5
- 230000003287 optical effect Effects 0.000 description 5
- 206010012689 Diabetic retinopathy Diseases 0.000 description 4
- 206010012688 Diabetic retinal oedema Diseases 0.000 description 3
- 201000011190 diabetic macular edema Diseases 0.000 description 3
- 230000035876 healing Effects 0.000 description 3
- 238000000015 thermotherapy Methods 0.000 description 3
- 235000008694 Humulus lupulus Nutrition 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- 208000007135 Retinal Neovascularization Diseases 0.000 description 2
- 208000017442 Retinal disease Diseases 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000001112 coagulating effect Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000002647 laser therapy Methods 0.000 description 2
- 238000013532 laser treatment Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 201000007914 proliferative diabetic retinopathy Diseases 0.000 description 2
- 210000001525 retina Anatomy 0.000 description 2
- 230000003685 thermal hair damage Effects 0.000 description 2
- 230000004393 visual impairment Effects 0.000 description 2
- 208000005590 Choroidal Neovascularization Diseases 0.000 description 1
- 206010060823 Choroidal neovascularisation Diseases 0.000 description 1
- 208000010412 Glaucoma Diseases 0.000 description 1
- 102000002812 Heat-Shock Proteins Human genes 0.000 description 1
- 108010004889 Heat-Shock Proteins Proteins 0.000 description 1
- 206010020843 Hyperthermia Diseases 0.000 description 1
- 206010025421 Macule Diseases 0.000 description 1
- 206010057430 Retinal injury Diseases 0.000 description 1
- 206010069652 Retinal phototoxicity Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000036031 hyperthermia Effects 0.000 description 1
- 238000002430 laser surgery Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000002186 photoactivation Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000000790 retinal pigment Substances 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 238000011272 standard treatment Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Images
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
- H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
- H01S3/09—Processes or apparatus for excitation, e.g. pumping
- H01S3/091—Processes or apparatus for excitation, e.g. pumping using optical pumping
- H01S3/094—Processes or apparatus for excitation, e.g. pumping using optical pumping by coherent light
- H01S3/0941—Processes or apparatus for excitation, e.g. pumping using optical pumping by coherent light of a laser diode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F9/00821—Methods or devices for eye surgery using laser for coagulation
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
- H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
- H01S3/10—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
- H01S3/106—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating by controlling devices placed within the cavity
- H01S3/108—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating by controlling devices placed within the cavity using non-linear optical devices, e.g. exhibiting Brillouin or Raman scattering
- H01S3/109—Frequency multiplication, e.g. harmonic generation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00844—Feedback systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
- A61F2009/00863—Retina
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
- H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
- H01S3/09—Processes or apparatus for excitation, e.g. pumping
- H01S3/091—Processes or apparatus for excitation, e.g. pumping using optical pumping
- H01S3/094—Processes or apparatus for excitation, e.g. pumping using optical pumping by coherent light
- H01S3/094076—Pulsed or modulated pumping
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
- H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
- H01S3/10—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
- H01S3/102—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating by controlling the active medium, e.g. by controlling the processes or apparatus for excitation
- H01S3/1022—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating by controlling the active medium, e.g. by controlling the processes or apparatus for excitation by controlling the optical pumping
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
- H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
- H01S3/10—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
- H01S3/13—Stabilisation of laser output parameters, e.g. frequency or amplitude
- H01S3/1305—Feedback control systems
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
- H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
- H01S3/10—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
- H01S3/13—Stabilisation of laser output parameters, e.g. frequency or amplitude
- H01S3/1306—Stabilisation of the amplitude
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
- H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
- H01S3/10—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
- H01S3/13—Stabilisation of laser output parameters, e.g. frequency or amplitude
- H01S3/131—Stabilisation of laser output parameters, e.g. frequency or amplitude by controlling the active medium, e.g. by controlling the processes or apparatus for excitation
- H01S3/1312—Stabilisation of laser output parameters, e.g. frequency or amplitude by controlling the active medium, e.g. by controlling the processes or apparatus for excitation by controlling the optical pumping
Landscapes
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Electromagnetism (AREA)
- Optics & Photonics (AREA)
- Ophthalmology & Optometry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Plasma & Fusion (AREA)
- Public Health (AREA)
- Nonlinear Science (AREA)
- Laser Surgery Devices (AREA)
- Radiation-Therapy Devices (AREA)
- Lasers (AREA)
Description
この例では、リソース18は、所望のパワーレベルを超えて3から5%に設定されるハードウェア光ループ閾値を有する。各パルスの最初では、要求された光レベルは最大に設定され、レーザパワーが所望のレベルに達するまでそこで保持される。これは、最速の立ち上がり時間を発生させる。レーザパワーが所望のレベルに達するとき、リソース18は、所望のレベルより高いパワーを保持する。リソース18は、その後、レーザパワーが所望のレベル以下になるまで要求されたパワーレベルを下げる。それが所望のレベル以下になったならば、ゆっくりとバックアップ(back up)に進む。もしそれが高いならば、ゆっくりと下方に下げられる。リソース18は、要求されたレベルを上下させる各決定の前に新たな計測をする。
この例では、レーザシステム10は、眼のRPE、カプロコリス(capullochoris)、及び脈絡膜を治療するのに利用される。パルス状の出力16は、眼のターゲット位置40に導かれ、ターゲット位置での温度上昇はパルスからパルスへ非加算的である。ターゲット位置40は、50マイクロから3mmの領域である。パルス状の出力16は、520から615nmの波長範囲を有する。パルス状の出力16は、25マイクロ秒から10,000マイクロ秒のパルスオンの時間と、750から10,000マイクロ秒のパルスオフの時間を有する。
この例では、レーザシステム10は、眼のRPE、カプロコリス(capullochoris)、及び脈絡膜を治療するのに利用される。パルス状の出力16は、眼のターゲット位置に導かれ、ターゲット位置での温度上昇はパルスからパルスへ非加算的である。ターゲット位置40は、50ミクロンから3mmの領域である。コントローラ22は、光検出器24からの信号をターゲットパワーと比較する高速回路を有しており、各パルスのオンとオフの時間を決定するのにこの比較を利用する。光検出器24からの信号は、オンとオフの時間を決定するためにターゲットパワーに対して比較される。
この実施例では、レーザシステム10は、眼のRPE、カプロコリス(capullochoris)、及び脈絡膜を治療するのに利用される。パルス状の出力16は、眼のターゲット位置に導かれ、ターゲット位置での温度上昇はパルスからパルスへ非加算的である。ターゲット位置40は、50ミクロンから3mmの領域である。パルス列16は、眼の網膜神経感覚上皮に影響を与えることなくRPEに対する熱の影響を封じ込めるように最適化されている。パルス列のオフ時間は、次のパルスがRPEターゲット位置に配信される前に、RPEターゲット位置が前のパルスの配信から鎮まるのに十分な時間を有していることを提供するための十分な存続時間である。
Claims (23)
- レーザシステムであって、
ダイオード励起源と、
前記ダイオード励起源によって励起される周波数二倍の固体可視レーザであって、パルス状のレーザ出力を生成する周波数二倍の固体可視レーザと、
ターゲット位置での熱の影響の実質的な閉じ込めのために提供する、オンとオフの時間を備えたパルス列を備えた前記パルス状の出力の作成のための命令を提供するリソースとを備え、
前記リソースは、前記ターゲット位置に配信されるレーザ光を監視するフィードバック制御システムを含んでいるレーザシステム。 - 前記パルス列は、前記ターゲット位置の熱の緩和時間より短い熱の緩和時間を有している請求項1に記載のシステム。
- 前記パルス列は、10ミリ秒より小さいパルス幅を有している請求項1に記載のシステム。
- 前記パルス列は、25マイクロ秒より大きなパルス幅を有している請求項1に記載のシステム。
- 前記パルス状の出力は、前記監視に応答して変更される請求項1に記載のシステム。
- 前記フィードバック制御システムは、制御信号を生成するコントローラを含んでいる請求項1に記載のシステム。
- 前記制御信号は、前記パルス状の出力を調整するのに用いられる請求項6に記載のシステム。
- 前記パルス列は、医療上の処置においてターゲット組織の熱の影響を封じ込めるように最適化されている請求項1に記載のシステム。
- 前記パルス列は、眼の網膜神経感覚上皮に影響を及ぼすことなく、RPEに対して熱の影響を封じ込めるように最適化されている請求項1に記載のシステム。
- 前記パルス列のオフ時間は、次のパルスが前記ターゲット位置に配信される前に、前記ターゲット位置が前のパルスの配信から鎮まるのに十分な時間を有することを提供するために十分な存続時間である請求項1に記載のシステム。
- 前記リソースは、熱の影響の封じ込めのために最適化されているオン時間を備えたパルス列を有するパルス状の出力に提供するために、正確なパラメータ及びトリガーを前記ダイオード励起源に提供する請求項1に記載のシステム。
- 前記命令は、ダイオードに対する開始電流を設定し、レーザからのターゲットパワーを設定し、ダイオードを起動するようにトリガーするステップを含んでいる請求項1に記載のシステム。
- 前記パルス状の出力は、ダイオード励起固体レーザに適当な可視範囲の波長を有している請求項1に記載のシステム。
- 前記パルス状の出力は、75から10,000マイクロ秒のパルスオフの時間を有している請求項1に記載のシステム。
- 前記リソースは、1つのターゲット位置に繰り返しのパルスを提供するように構成されている請求項1に記載のシステム。
- 前記周波数二倍の固体可視レーザは、Nd:YAG、Nd:YVO4、Nd:YLF、Ho:YAG、Er:YAG、Yb:YAG、Yb:YVO4から選択されるゲイン媒体を有している請求項1に記載のシステム。
- ダイオード励起源であって、該ダイオード励起源によって励起されパルス状の出力を生成する周波数二倍の固体可視レーザに結合されるダイオード励起源と、
光検出器の信号に応答して、熱の影響を実質的に封じ込め得るオンとオフの時間を備えたパルス列を有するパルス状の出力を作成するために前記周波数二倍の固体可視レーザに命令を提供するコントローラとを備え、
前記コントローラは、光検出器の信号をターゲットパワーと比較し、この比較をオンとオフの時間を決定するために用いるプロセッサを含んでいるレーザ治療システム。 - 前記コントローラは、光検出器信号をターゲットパワーと比較し、この比較を各パルスのオンとオフの時間を決定するのに用いる高速回路を含んでいる請求項17に記載のシステム。
- 前記コントローラは、光検出器信号をターゲットパワーと比較し、この比較をオンとオフの時間を決定するのに用いる高速回路及びプロセッサを含んでいる請求項17に記載のシステム。
- 前記パルス列は、パルスごとに、10ミリ秒より小さく、25マイクロ秒より大きいオンの時間を有している請求項17に記載のシステム。
- 前記パルス状の出力のパワー変動が所望のパワーの10%未満であるように、前記リソースを前記パルス状の出力に接続する光検出器を更に備えている請求項1に記載のシステム。
- 前記パルス状の出力が所望のパワーを5%上回ることがないように、前記パルス状の出力は、パルス列のオンの時間及びオフの時間の少なくとも一方を調節することによって調節される請求項7に記載のシステム。
- 前記十分な存続時間は、前記ターゲット位置での温度上昇がパルスからパルスへは非加算的であるように提供される請求項10に記載のシステム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/066,615 US7771417B2 (en) | 2005-02-24 | 2005-02-24 | Laser system with short pulse characteristics and its methods of use |
US11/066,615 | 2005-02-24 | ||
PCT/US2006/006369 WO2006091714A2 (en) | 2005-02-24 | 2006-02-22 | Laser system with short pulse characteristics and its methods of use |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2008531129A JP2008531129A (ja) | 2008-08-14 |
JP2008531129A5 JP2008531129A5 (ja) | 2009-04-09 |
JP5133069B2 true JP5133069B2 (ja) | 2013-01-30 |
Family
ID=36912664
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007557145A Active JP5133069B2 (ja) | 2005-02-24 | 2006-02-22 | 短パルス特性を有するレーザシステム及びその使用方法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US7771417B2 (ja) |
EP (2) | EP3009093B1 (ja) |
JP (1) | JP5133069B2 (ja) |
HK (1) | HK1223536A1 (ja) |
WO (1) | WO2006091714A2 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2015504322A (ja) * | 2011-10-20 | 2015-02-12 | トプコン・メディカル・レーザー・システムズ・インコーポレイテッドTopcon Medical Laser Systems, Inc. | エンドポイントが管理される光凝固 |
KR101914742B1 (ko) | 2017-04-28 | 2018-11-02 | 주식회사 루트로닉 | 피부 치료용 레이저 장치 |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7771417B2 (en) * | 2005-02-24 | 2010-08-10 | Iridex Corporation | Laser system with short pulse characteristics and its methods of use |
US7760411B2 (en) * | 2006-11-20 | 2010-07-20 | Alcon, Inc. | System and method for illumination attenuation |
JP4970068B2 (ja) * | 2007-01-30 | 2012-07-04 | 株式会社ニデック | 眼科用レーザ治療装置 |
US8945103B2 (en) | 2007-10-30 | 2015-02-03 | Iridex Corporation | Contact probe for the delivery of laser energy |
JP2012503798A (ja) | 2008-09-25 | 2012-02-09 | ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク | 構造物の光刺激およびイメージングを提供するためのデバイス、装置、および方法 |
SG185517A1 (en) | 2010-05-10 | 2012-12-28 | Univ Ramot | System for treating glaucoma by directing electromagnetic energy to the limbal area of an eye |
US11771596B2 (en) | 2010-05-10 | 2023-10-03 | Ramot At Tel-Aviv University Ltd. | System and method for treating an eye |
US8351477B2 (en) * | 2010-07-22 | 2013-01-08 | Coherent Gmbh | Modulation method for diode-laser pumped lasers |
US9610124B2 (en) | 2011-03-25 | 2017-04-04 | Precision Medical Optics, Llc | Medical laser with electronic shutter |
US10238541B2 (en) | 2011-10-19 | 2019-03-26 | Iridex Corporation | Short duration pulse grid pattern laser treatment and methods |
US9278029B2 (en) | 2011-10-19 | 2016-03-08 | Iridex Corporation | Short duration pulse grid pattern laser treatment and methods |
US10874873B2 (en) | 2012-05-25 | 2020-12-29 | Ojai Retinal Technology, Llc | Process utilizing pulsed energy to heat treat biological tissue |
US10953241B2 (en) | 2012-05-25 | 2021-03-23 | Ojai Retinal Technology, Llc | Process for providing protective therapy for biological tissues or fluids |
US10596389B2 (en) | 2012-05-25 | 2020-03-24 | Ojai Retinal Technology, Llc | Process and system for utilizing energy to treat biological tissue |
US10894169B2 (en) | 2012-05-25 | 2021-01-19 | Ojai Retinal Technology, Llc | System and method for preventing or treating Alzheimer's and other neurodegenerative diseases |
US10219947B2 (en) | 2012-05-25 | 2019-03-05 | Ojai Retinal Technology, Llc | System and process for retina phototherapy |
US9381116B2 (en) | 2012-05-25 | 2016-07-05 | Ojai Retinal Technology, Llc | Subthreshold micropulse laser prophylactic treatment for chronic progressive retinal diseases |
US9962291B2 (en) | 2012-05-25 | 2018-05-08 | Ojai Retinal Technology, Llc | System and process for neuroprotective therapy for glaucoma |
US10531908B2 (en) | 2012-05-25 | 2020-01-14 | Ojai Retinal Technology, Llc | Method for heat treating biological tissues using pulsed energy sources |
US10076671B2 (en) | 2012-05-25 | 2018-09-18 | Ojai Retinal Technology, Llc | Apparatus for retina phototherapy |
US9381115B2 (en) | 2012-05-25 | 2016-07-05 | Ojai Retinal Technology, Llc | System and process for retina phototherapy |
US9168174B2 (en) | 2012-05-25 | 2015-10-27 | Ojai Retinal Technology, Llc | Process for restoring responsiveness to medication in tissue of living organisms |
US9427602B2 (en) | 2012-05-25 | 2016-08-30 | Ojai Retinal Technology, Llc | Pulsating electromagnetic and ultrasound therapy for stimulating targeted heat shock proteins and facilitating protein repair |
US10278863B2 (en) | 2016-03-21 | 2019-05-07 | Ojai Retinal Technology, Llc | System and process for treatment of myopia |
US11077318B2 (en) | 2012-05-25 | 2021-08-03 | Ojai Retinal Technology, Llc | System and process of utilizing energy for treating biological tissue |
US10589120B1 (en) | 2012-12-31 | 2020-03-17 | Gary John Bellinger | High-intensity laser therapy method and apparatus |
CN106456371B (zh) * | 2013-11-12 | 2020-04-03 | O·瑟德阿瑞维克 | 角膜玻璃化、产生角膜玻璃化的方法和装置以及该装置的使用方法 |
AU2015277050A1 (en) | 2014-06-19 | 2017-01-05 | Visumedics, Inc. | Diagnostic and surgical laser device utilizing a visible laser diode |
US9700461B2 (en) | 2014-06-27 | 2017-07-11 | Iridex Corporation | Convex contact probe for the delivery of laser energy |
US20160143692A1 (en) | 2014-11-22 | 2016-05-26 | Candela Corporation | Laser System For Skin Treatment |
EP3368154B1 (en) * | 2015-10-27 | 2020-10-14 | Visumedics Inc. | Laser system with pulse modulation |
US10709608B2 (en) | 2016-03-21 | 2020-07-14 | Ojai Retinal Technology, Llc | System and process for prevention of myopia |
DE102016205914A1 (de) * | 2016-04-08 | 2017-10-12 | Carl Zeiss Meditec Ag | Verfahren zur selektiven, minimal invasiven Lasertherapie am Auge |
CN109414291B (zh) | 2016-06-30 | 2022-03-29 | 艾瑞黛克斯公司 | 具有可更换的接触尖端和治疗引导件的手持式眼科激光系统 |
US10263384B2 (en) * | 2016-10-14 | 2019-04-16 | Lumenis Ltd. | Laser system having a dual pulse-length regime |
CA3004065C (en) | 2017-05-05 | 2023-02-14 | Institut National D'optique | Light modulation for improved photoacoustic feedback on light-induced treatments and procedures |
JP7128278B2 (ja) * | 2017-12-20 | 2022-08-30 | ムーグ インコーポレイテッド | 付加製造画像の畳み込みニューラルネットワーク評価、及びこれに基づく付加製造システム |
RU2668706C1 (ru) * | 2018-02-15 | 2018-10-02 | Федеральное государственное автономное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации | Способ лазерного лечения фокального диабетического макулярного отека |
AU2019297135B2 (en) | 2018-07-02 | 2022-05-19 | Belkin Vision Ltd. | Direct selective laser trabeculoplasty |
EP3843642A4 (en) * | 2018-08-31 | 2022-06-08 | Iridex Corporation | METHODS AND SYSTEMS FOR LARGE SPOT LASER TREATMENT OF THE RETINA |
US11684514B2 (en) | 2018-09-26 | 2023-06-27 | Norlase Aps | Direct diode laser module for delivering pulsed visible green laser energy |
US11612315B2 (en) | 2020-04-09 | 2023-03-28 | Vialase, Inc. | Alignment and diagnostic device and methods for imaging and surgery at the irido-corneal angle of the eye |
WO2022026233A1 (en) * | 2020-07-27 | 2022-02-03 | Ojai Retinal Technology, Llc | Retinal irradiation system and method to improve ocular function and health in the normally aging eye |
CA3220257A1 (en) * | 2021-06-08 | 2022-12-15 | Jeffrey K. LUTTRULL | Retinal phototherapy system and method having fixed parameters |
US12002567B2 (en) | 2021-11-29 | 2024-06-04 | Vialase, Inc. | System and method for laser treatment of ocular tissue based on patient biometric data and apparatus and method for determining laser energy based on an anatomical model |
WO2023131791A1 (en) * | 2022-01-10 | 2023-07-13 | Renishaw Plc | Energy beam exposures in powder bed fusion |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4916319A (en) * | 1988-04-22 | 1990-04-10 | Tauton Technologies, Inc. | Beam intensity profilometer |
US4885471A (en) * | 1988-04-22 | 1989-12-05 | Taunton Technologies, Inc. | Ultraviolet radiometer |
US6099522A (en) * | 1989-02-06 | 2000-08-08 | Visx Inc. | Automated laser workstation for high precision surgical and industrial interventions |
US5151909A (en) * | 1990-10-16 | 1992-09-29 | Laserscope | Frequency doubled solid state laser having programmable pump power modes and method for controllable lasers |
US5302259A (en) * | 1991-04-30 | 1994-04-12 | Reginald Birngruber | Method and apparatus for altering the properties in light absorbing material |
US5556395A (en) * | 1993-05-07 | 1996-09-17 | Visx Incorporated | Method and system for laser treatment of refractive error using an offset image of a rotatable mask |
US5549596A (en) | 1993-07-07 | 1996-08-27 | The General Hospital Corporation | Selective laser targeting of pigmented ocular cells |
US5982789A (en) * | 1995-11-22 | 1999-11-09 | Light Solutions Corporation | Pulsed laser with passive stabilization |
US5757831A (en) * | 1996-07-12 | 1998-05-26 | Lightwave Electronics Corp. | Electronic suppression of optical feedback instabilities in a solid-state laser |
US5892569A (en) * | 1996-11-22 | 1999-04-06 | Jozef F. Van de Velde | Scanning laser ophthalmoscope optimized for retinal microphotocoagulation |
DE19837692C2 (de) * | 1998-08-19 | 2003-04-03 | Bentec Gmbh Drilling & Oilfield Systems | Bohrvorrichtung, Bohranlage und Verfahren zum Abteufen einer Explorations- und Förderbohrung |
US6130900A (en) | 1999-03-05 | 2000-10-10 | Coherent, Inc. | Pulsed intracavity frequency-converted solid-state laser with long-pulse simulation |
DE19958566A1 (de) | 1999-12-04 | 2001-06-07 | Zeiss Carl Jena Gmbh | Gütegeschalteter Festkörperlaser mit einstellbarer Pulslänge |
WO2001078830A2 (en) | 2000-04-17 | 2001-10-25 | Medelaser, Llc | Photostimulaton treatment apparatus and methods for use |
WO2001080792A2 (en) | 2000-04-27 | 2001-11-01 | Iridex Corporation | Method and apparatus for real-time detection, control and recording of sub-clinical therapeutic laser lesions during ocular laser photocoagulation |
AU2001275129A1 (en) * | 2000-06-01 | 2001-12-11 | The General Hospital Corporation | Selective photocoagulation |
EP1184948A3 (en) | 2000-08-28 | 2004-10-20 | Laser Alignment, Inc. | Diode pumped solid state lasers |
FR2815737B1 (fr) | 2000-10-25 | 2003-01-24 | Centre Nat Etd Spatiales | Dispositif et procede de codage pour un sous-ensemble de detection et correction d'erreurs memoire dans un systeme electronique |
DE10100857B4 (de) * | 2001-01-11 | 2006-05-18 | Carl Zeiss Jena Gmbh | Laserspaltlampe mit Laserstrahlungsquelle |
US20030078567A1 (en) | 2001-04-27 | 2003-04-24 | Giorgio Dorin | Method and apparatus for laser ThermoProtectiveTreatment(TPT) with pre-programmed variable irradiance long exposures |
AU2003230742A1 (en) | 2002-04-12 | 2003-10-27 | Iridex Corporation | Low power laser therapy control |
EP1549211A2 (en) | 2002-09-20 | 2005-07-06 | Iridex Corporation | Apparatus for real time measure/control of intra-operative effects during laser thermal treatments using light scattering |
US20040116909A1 (en) * | 2002-12-11 | 2004-06-17 | Ceramoptec Industries Inc. | Multipurpose diode laser system for ophthalmic laser treatments |
DE10331792A1 (de) | 2003-07-11 | 2005-02-17 | Medizinisches Laserzentrum Lübeck GmbH | Laser mit Dosiemetriesteuerung |
US7771417B2 (en) * | 2005-02-24 | 2010-08-10 | Iridex Corporation | Laser system with short pulse characteristics and its methods of use |
US9381116B2 (en) | 2012-05-25 | 2016-07-05 | Ojai Retinal Technology, Llc | Subthreshold micropulse laser prophylactic treatment for chronic progressive retinal diseases |
US9381115B2 (en) | 2012-05-25 | 2016-07-05 | Ojai Retinal Technology, Llc | System and process for retina phototherapy |
-
2005
- 2005-02-24 US US11/066,615 patent/US7771417B2/en active Active
-
2006
- 2006-02-22 WO PCT/US2006/006369 patent/WO2006091714A2/en active Application Filing
- 2006-02-22 EP EP15196827.8A patent/EP3009093B1/en active Active
- 2006-02-22 EP EP06735857.2A patent/EP1856774B1/en not_active Revoked
- 2006-02-22 JP JP2007557145A patent/JP5133069B2/ja active Active
-
2016
- 2016-10-19 HK HK16112037.2A patent/HK1223536A1/zh unknown
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2015504322A (ja) * | 2011-10-20 | 2015-02-12 | トプコン・メディカル・レーザー・システムズ・インコーポレイテッドTopcon Medical Laser Systems, Inc. | エンドポイントが管理される光凝固 |
US9642747B2 (en) | 2011-10-20 | 2017-05-09 | Topcon Medical Laser Systems, Inc. | Endpoint-managed photocoagulation |
KR101914742B1 (ko) | 2017-04-28 | 2018-11-02 | 주식회사 루트로닉 | 피부 치료용 레이저 장치 |
Also Published As
Publication number | Publication date |
---|---|
EP3009093A1 (en) | 2016-04-20 |
JP2008531129A (ja) | 2008-08-14 |
HK1223536A1 (zh) | 2017-08-04 |
WO2006091714A2 (en) | 2006-08-31 |
US20060187978A1 (en) | 2006-08-24 |
EP1856774A4 (en) | 2010-02-10 |
EP3009093B1 (en) | 2023-12-27 |
WO2006091714A3 (en) | 2007-10-25 |
US7771417B2 (en) | 2010-08-10 |
EP1856774B1 (en) | 2016-06-08 |
EP1856774A2 (en) | 2007-11-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5133069B2 (ja) | 短パルス特性を有するレーザシステム及びその使用方法 | |
JP6701266B2 (ja) | 多機能治療レーザによる温度制御された複合レーザ治療方法及び装置 | |
Dorin | Subthreshold and micropulse diode laser photocoagulation | |
Mainster | Wavelength selection in macular photocoagulation: tissue optics, thermal effects, and laser systems | |
US6319274B1 (en) | Devices and techniques for light-mediated stimulation of trabecular meshwork in glaucoma therapy | |
Mainster | Decreasing retinal photocoagulation damage: principles and techniques | |
EP3368154B1 (en) | Laser system with pulse modulation | |
JP5629753B2 (ja) | 治療光線によって治療される生体組織における非侵襲性の温度決定方法および装置 | |
US20060259021A1 (en) | Diode-laser-pumped ultraviolet and infrared lasers for ablation and coagulation of soft tissue | |
US8574224B2 (en) | Surgical laser device utilizing a visible laser diode | |
AU2021215167B2 (en) | System and process for retina phototherapy | |
Framme et al. | Threshold determinations for selective retinal pigment epithelium damage with repetitive pulsed microsecond laser systems in rabbits | |
McHugh et al. | Irradiation of rabbit retina with diode and Nd: YAG lasers. | |
McHugh et al. | Diode laser contact transscleral retinal photocoagulation: a clinical study. | |
Bessette et al. | Laser light: its nature and its action on the eye. | |
MCMULLEN et al. | Comparison of retinal photocoagulation using pulsed frequency-doubled neodymium-YAG and argon green laser | |
CN113230026B (zh) | 在眼睛处进行微创的、细胞选择性的激光治疗的激光系统 | |
Lin | Accommodative Gain in Presbyopic Eye Using a New Procedure of Laser Scleral Softening (LSS): Part-II. Formulas for Volume Efficacy | |
Gupta et al. | Newer Ophthalmic Laser Systems | |
Ip et al. | Laser photocoagulation | |
Dahotre et al. | Lasers Processing in Medicine and Surgery | |
Sramek et al. | Improved safety of retinal photocoagulation with a shaped beam and modulated pulse | |
Rock | Lasers in Ophthalmology | |
Moseley | 21 Laser–tissue Interactions |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20090219 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20090219 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20110324 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20110404 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20110704 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20110711 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20110728 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20120130 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20120501 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20120510 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20120727 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20121009 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20121107 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20151116 Year of fee payment: 3 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5133069 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |