JP5121822B2 - バイオセンサ用異常出力検出システム - Google Patents

バイオセンサ用異常出力検出システム Download PDF

Info

Publication number
JP5121822B2
JP5121822B2 JP2009510115A JP2009510115A JP5121822B2 JP 5121822 B2 JP5121822 B2 JP 5121822B2 JP 2009510115 A JP2009510115 A JP 2009510115A JP 2009510115 A JP2009510115 A JP 2009510115A JP 5121822 B2 JP5121822 B2 JP 5121822B2
Authority
JP
Japan
Prior art keywords
pulse
polling
assay
output signal
input signal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2009510115A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009536744A5 (OSRAM
JP2009536744A (ja
Inventor
カーペンター,スコット・イー
ネルソン,クリスティーン・ディー
ウー,フアン−ピン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Healthcare LLC
Original Assignee
Bayer Healthcare LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare LLC filed Critical Bayer Healthcare LLC
Publication of JP2009536744A publication Critical patent/JP2009536744A/ja
Publication of JP2009536744A5 publication Critical patent/JP2009536744A5/ja
Application granted granted Critical
Publication of JP5121822B2 publication Critical patent/JP5121822B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3273Devices therefor, e.g. test element readers, circuitry
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/10Analysis or design of chemical reactions, syntheses or processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Emergency Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
JP2009510115A 2006-05-08 2007-05-07 バイオセンサ用異常出力検出システム Active JP5121822B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74677106P 2006-05-08 2006-05-08
US60/746,771 2006-05-08
PCT/US2007/068320 WO2007133985A2 (en) 2006-05-08 2007-05-07 Abnormal output detection system for a biosensor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012182103A Division JP5373948B2 (ja) 2006-05-08 2012-08-21 バイオセンサ用異常出力検出システム

Publications (3)

Publication Number Publication Date
JP2009536744A JP2009536744A (ja) 2009-10-15
JP2009536744A5 JP2009536744A5 (OSRAM) 2010-06-17
JP5121822B2 true JP5121822B2 (ja) 2013-01-16

Family

ID=38543641

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009510115A Active JP5121822B2 (ja) 2006-05-08 2007-05-07 バイオセンサ用異常出力検出システム
JP2012182103A Active JP5373948B2 (ja) 2006-05-08 2012-08-21 バイオセンサ用異常出力検出システム

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012182103A Active JP5373948B2 (ja) 2006-05-08 2012-08-21 バイオセンサ用異常出力検出システム

Country Status (11)

Country Link
US (2) US8234076B2 (OSRAM)
EP (1) EP2020909A2 (OSRAM)
JP (2) JP5121822B2 (OSRAM)
CN (1) CN101437443B (OSRAM)
BR (1) BRPI0711433A2 (OSRAM)
CA (1) CA2650880C (OSRAM)
MX (1) MX2008014250A (OSRAM)
NO (1) NO20084960L (OSRAM)
RU (1) RU2465812C2 (OSRAM)
TW (1) TWI431273B (OSRAM)
WO (1) WO2007133985A2 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3172559B2 (ja) 1991-11-20 2001-06-04 株式会社クラレ 艶消しフィルム

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2553632A1 (en) 2004-02-06 2005-08-25 Bayer Healthcare Llc Oxidizable species as an internal reference for biosensors and method of use
US8529751B2 (en) 2006-03-31 2013-09-10 Lifescan, Inc. Systems and methods for discriminating control solution from a physiological sample
US7966859B2 (en) 2006-05-03 2011-06-28 Bayer Healthcare Llc Underfill detection system for a biosensor
EP2020909A2 (en) * 2006-05-08 2009-02-11 Bayer HealthCare LLC Abnormal output detection system for a biosensor
EP2029707A2 (en) 2006-05-08 2009-03-04 The Lubrizol Corporation Lubricating composition containing a polymer and antiwear agents
US8778168B2 (en) 2007-09-28 2014-07-15 Lifescan, Inc. Systems and methods of discriminating control solution from a physiological sample
EP2222867B1 (en) * 2007-12-10 2018-07-11 Ascensia Diabetes Care Holdings AG Rapid-read gated amperometry
CA2708038A1 (en) * 2007-12-10 2009-09-03 Bayer Healthcare Llc Slope-based compensation
WO2009076302A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Control markers for auto-detection of control solution and methods of use
US8603768B2 (en) * 2008-01-17 2013-12-10 Lifescan, Inc. System and method for measuring an analyte in a sample
US8551320B2 (en) 2008-06-09 2013-10-08 Lifescan, Inc. System and method for measuring an analyte in a sample
EP2373984B1 (en) * 2008-12-08 2022-11-30 Ascensia Diabetes Care Holdings AG Biosensor signal adjustment
DE102009048811B4 (de) * 2009-10-08 2013-07-18 Eads Deutschland Gmbh Biosensorvorrichtung mit Selbsttesteinrichtung
KR101929057B1 (ko) * 2010-03-22 2018-12-13 바이엘 헬쓰케어 엘엘씨 바이오센서를 위한 잔여 보상
CA3047242A1 (en) 2010-06-07 2011-12-15 Ascensia Diabetes Care Holdings Ag Underfill management system for a biosensor
CA2798938C (en) 2010-06-07 2018-08-07 Bayer Healthcare Llc Slope-based compensation including secondary output signals
US8923918B2 (en) * 2010-12-18 2014-12-30 Kallows Engineering India Pvt. Ltd. Biosensor interface apparatus for a mobile communication device
US9008744B2 (en) 2011-05-06 2015-04-14 Medtronic Minimed, Inc. Method and apparatus for continuous analyte monitoring
US9775806B2 (en) 2011-09-21 2017-10-03 Ascensia Diabetes Care Holdings Ag Analysis compensation including segmented signals
US9810688B2 (en) * 2013-03-15 2017-11-07 Robert Bosch Gmbh Smart glass slide for microarrays
US9080196B2 (en) 2012-09-28 2015-07-14 Cilag Gmbh International System and method for determining hematocrit insensitive glucose concentration
US9005426B2 (en) 2012-09-28 2015-04-14 Cilag Gmbh International System and method for determining hematocrit insensitive glucose concentration
US9958410B2 (en) * 2013-03-14 2018-05-01 Ascensia Diabetes Care Holdings Ag Normalized calibration of analyte concentration determinations
JP6356707B2 (ja) * 2013-03-15 2018-07-11 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 電気化学的測定中に高抗酸化物質レベルを検出してそれから分析物濃度をフェイルセイフする方法並びにそれを組み込んだデバイス、装置、及びシステム
EP2972268B1 (en) * 2013-03-15 2017-05-24 Roche Diabetes Care GmbH Methods of failsafing electrochemical measurements of an analyte as well as devices, apparatuses and systems incorporating the same
CN104122882A (zh) * 2013-04-24 2014-10-29 中烟机械技术中心有限责任公司 巴鲁夫自诊断型传感器的故障诊断系统
CN105445341B (zh) * 2014-09-12 2018-10-16 达尔生技股份有限公司 电化学的检测试片异常的检测方法
TWI567387B (zh) * 2014-09-12 2017-01-21 達爾生技股份有限公司 電化學的感測試片本身性質之異常的檢測方法
CN108603853B (zh) * 2016-02-10 2022-08-09 索尼公司 电特性测量用样本、电特性测量装置和电特性测量方法
CN110249219B (zh) * 2016-12-05 2022-08-23 安晟信医疗科技控股公司 风险因素监测
KR102031340B1 (ko) * 2018-03-14 2019-10-11 주식회사 필로시스 혈당 측정 장치, 방법, 및 시스템
US11382541B2 (en) 2018-11-16 2022-07-12 Medtronic Minimed, Inc. Miniaturized analyte sensor
KR102532761B1 (ko) * 2019-08-02 2023-05-16 바이오나임 코포레이션 마이크로 바이오센서의 측정 간섭 감소 방법
TWI870545B (zh) * 2020-02-21 2025-01-21 美商半導體組件工業公司 用於測量工作電極電流之方法、雙向恆電位器、及電池測量系統
CN111681713B (zh) * 2020-06-10 2023-03-31 重庆邮电大学 一种包含退相干作用的聚合物分子电学性质的模型构建方法及其应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431004A (en) 1981-10-27 1984-02-14 Bessman Samuel P Implantable glucose sensor
US4750496A (en) 1987-01-28 1988-06-14 Xienta, Inc. Method and apparatus for measuring blood glucose concentration
US5508171A (en) 1989-12-15 1996-04-16 Boehringer Mannheim Corporation Assay method with enzyme electrode system
US5243516A (en) * 1989-12-15 1993-09-07 Boehringer Mannheim Corporation Biosensing instrument and method
FR2701117B1 (fr) 1993-02-04 1995-03-10 Asulab Sa Système de mesures électrochimiques à capteur multizones, et son application au dosage du glucose.
US5366609A (en) 1993-06-08 1994-11-22 Boehringer Mannheim Corporation Biosensing meter with pluggable memory key
IE72524B1 (en) * 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
US6153069A (en) 1995-02-09 2000-11-28 Tall Oak Ventures Apparatus for amperometric Diagnostic analysis
US5582697A (en) 1995-03-17 1996-12-10 Matsushita Electric Industrial Co., Ltd. Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same
US5620579A (en) 1995-05-05 1997-04-15 Bayer Corporation Apparatus for reduction of bias in amperometric sensors
EP0958495B1 (en) 1997-02-06 2002-11-13 Therasense, Inc. Small volume in vitro analyte sensor
US6391645B1 (en) 1997-05-12 2002-05-21 Bayer Corporation Method and apparatus for correcting ambient temperature effect in biosensors
AU3849799A (en) * 1998-05-20 1999-12-06 Arkray, Inc. Method and apparatus for electrochemical measurement using statistical technique
JP4321966B2 (ja) * 1998-11-02 2009-08-26 アルザ・コーポレーション 適合性抗微生物剤を含有する電気輸送式デバイス
CA2305922C (en) 1999-08-02 2005-09-20 Bayer Corporation Improved electrochemical sensor design
GB0005564D0 (en) * 2000-03-08 2000-05-03 Inverness Medical Ltd Measurjement of substances in liquid
ATE507766T1 (de) * 2002-03-22 2011-05-15 Animas Technologies Llc Leistungsverbesserung einer analytenüberwachungsvorrichtung
US20040222965A1 (en) * 2003-05-05 2004-11-11 Riccomini Roy J. System and method for generating an analog signal in a hand-held computing device
US7488601B2 (en) * 2003-06-20 2009-02-10 Roche Diagnostic Operations, Inc. System and method for determining an abused sensor during analyte measurement
WO2005114163A1 (en) 2004-05-14 2005-12-01 Bayer Healthcare Llc Methods for performing hematocrit adjustment in glucose assays and devices for same
EP1913374B1 (en) 2005-07-20 2019-01-09 Ascensia Diabetes Care Holdings AG Method for signalling the user to add additional sample to a test strip, method for measuring the temperature of a sample and methods for determining the concentration of an analyte based on gated amperometry
EP3483598B1 (en) 2005-09-30 2024-11-06 Ascensia Diabetes Care Holdings AG Gated voltammetry
EP2020909A2 (en) * 2006-05-08 2009-02-11 Bayer HealthCare LLC Abnormal output detection system for a biosensor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3172559B2 (ja) 1991-11-20 2001-06-04 株式会社クラレ 艶消しフィルム

Also Published As

Publication number Publication date
HK1132643A1 (en) 2010-03-05
CA2650880A1 (en) 2007-11-22
TWI431273B (zh) 2014-03-21
US8234076B2 (en) 2012-07-31
US9301717B2 (en) 2016-04-05
US20090099787A1 (en) 2009-04-16
JP2012255803A (ja) 2012-12-27
CN101437443B (zh) 2011-11-30
RU2465812C2 (ru) 2012-11-10
BRPI0711433A2 (pt) 2011-11-16
US20120271559A1 (en) 2012-10-25
CA2650880C (en) 2015-11-24
JP2009536744A (ja) 2009-10-15
JP5373948B2 (ja) 2013-12-18
CN101437443A (zh) 2009-05-20
NO20084960L (no) 2008-11-26
TW200804805A (en) 2008-01-16
RU2008148133A (ru) 2010-06-20
WO2007133985A3 (en) 2008-01-10
MX2008014250A (es) 2008-11-26
EP2020909A2 (en) 2009-02-11
WO2007133985A2 (en) 2007-11-22

Similar Documents

Publication Publication Date Title
JP5121822B2 (ja) バイオセンサ用異常出力検出システム
JP5372744B2 (ja) バイオセンサ用の充填量不足検出システム
JP6448504B2 (ja) 勾配ベース補正
US10724985B2 (en) Biosensor for determining a concentration of a biosensor using an underfill procedure
JP5039062B2 (ja) バイオセンサー系における温度補正被分析物決定
JP2011506966A5 (OSRAM)
HK1132643B (en) Abnormal output detection system for a biosensor
HK1133080B (en) Underfill detection system for an electrochemical biosensor

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100427

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20100427

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20111117

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20111122

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120222

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120229

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120322

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120329

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120423

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120521

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120821

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20120924

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20121023

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20151102

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

Ref document number: 5121822

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250