CA2650880C - Abnormal output detection system for a biosensor - Google Patents

Abnormal output detection system for a biosensor Download PDF

Info

Publication number
CA2650880C
CA2650880C CA2650880A CA2650880A CA2650880C CA 2650880 C CA2650880 C CA 2650880C CA 2650880 A CA2650880 A CA 2650880A CA 2650880 A CA2650880 A CA 2650880A CA 2650880 C CA2650880 C CA 2650880C
Authority
CA
Canada
Prior art keywords
pulse
polling
assay
input signal
output signal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2650880A
Other languages
English (en)
French (fr)
Other versions
CA2650880A1 (en
Inventor
Scott E. Carpenter
Christine D. Nelson
Huan-Ping Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ascensia Diabetes Care Holdings AG
Original Assignee
Bayer Healthcare LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare LLC filed Critical Bayer Healthcare LLC
Publication of CA2650880A1 publication Critical patent/CA2650880A1/en
Application granted granted Critical
Publication of CA2650880C publication Critical patent/CA2650880C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3273—Devices therefor, e.g. test element readers, circuitry
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/10—Analysis or design of chemical reactions, syntheses or processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Emergency Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Electrochemistry (AREA)
  • Physiology (AREA)
CA2650880A 2006-05-08 2007-05-07 Abnormal output detection system for a biosensor Expired - Fee Related CA2650880C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74677106P 2006-05-08 2006-05-08
US60/746,771 2006-05-08
PCT/US2007/068320 WO2007133985A2 (en) 2006-05-08 2007-05-07 Abnormal output detection system for a biosensor

Publications (2)

Publication Number Publication Date
CA2650880A1 CA2650880A1 (en) 2007-11-22
CA2650880C true CA2650880C (en) 2015-11-24

Family

ID=38543641

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2650880A Expired - Fee Related CA2650880C (en) 2006-05-08 2007-05-07 Abnormal output detection system for a biosensor

Country Status (11)

Country Link
US (2) US8234076B2 (OSRAM)
EP (1) EP2020909A2 (OSRAM)
JP (2) JP5121822B2 (OSRAM)
CN (1) CN101437443B (OSRAM)
BR (1) BRPI0711433A2 (OSRAM)
CA (1) CA2650880C (OSRAM)
MX (1) MX2008014250A (OSRAM)
NO (1) NO20084960L (OSRAM)
RU (1) RU2465812C2 (OSRAM)
TW (1) TWI431273B (OSRAM)
WO (1) WO2007133985A2 (OSRAM)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3172559B2 (ja) 1991-11-20 2001-06-04 株式会社クラレ 艶消しフィルム
EP1713926B1 (en) 2004-02-06 2012-08-01 Bayer HealthCare, LLC Oxidizable species as an internal reference for biosensors and method of use
US8529751B2 (en) 2006-03-31 2013-09-10 Lifescan, Inc. Systems and methods for discriminating control solution from a physiological sample
US7966859B2 (en) 2006-05-03 2011-06-28 Bayer Healthcare Llc Underfill detection system for a biosensor
CA2651876A1 (en) 2006-05-08 2007-11-22 The Lubrizol Corporation Lubricating composition containing a polymer and antiwear agents
CA2650880C (en) * 2006-05-08 2015-11-24 Bayer Healthcare Llc Abnormal output detection system for a biosensor
US8778168B2 (en) 2007-09-28 2014-07-15 Lifescan, Inc. Systems and methods of discriminating control solution from a physiological sample
BRPI0820718A2 (pt) * 2007-12-10 2015-06-16 Bayer Healthcare Llc Amperometria com porta de leitura rápida
MX2010006392A (es) * 2007-12-10 2010-07-02 Bayer Healthcare Llc Compensacion basada en la pendiente.
WO2009076302A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Control markers for auto-detection of control solution and methods of use
US8603768B2 (en) 2008-01-17 2013-12-10 Lifescan, Inc. System and method for measuring an analyte in a sample
US8551320B2 (en) 2008-06-09 2013-10-08 Lifescan, Inc. System and method for measuring an analyte in a sample
RU2509304C2 (ru) 2008-12-08 2014-03-10 БАЙЕР ХЕЛТКЭА ЭлЭлСи Биосенсорная система с корректировкой сигнала
DE102009048811B4 (de) * 2009-10-08 2013-07-18 Eads Deutschland Gmbh Biosensorvorrichtung mit Selbsttesteinrichtung
RU2568884C2 (ru) 2010-03-22 2015-11-20 БАЙЕР ХЕЛТКЭА ЭлЭлСи Компенсация невязки для биодатчика
BR112012031375A2 (pt) 2010-06-07 2016-10-25 Bayer Healthcare Llc sistema de gerenciamento de enchimento abaixo do necessário para um biosensor
WO2011156152A1 (en) 2010-06-07 2011-12-15 Bayer Healthcare Llc Slope-based compensation including secondary output signals
US8923918B2 (en) * 2010-12-18 2014-12-30 Kallows Engineering India Pvt. Ltd. Biosensor interface apparatus for a mobile communication device
US9008744B2 (en) * 2011-05-06 2015-04-14 Medtronic Minimed, Inc. Method and apparatus for continuous analyte monitoring
JP6082396B2 (ja) 2011-09-21 2017-02-15 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ 誤差補償を伴うバイオセンサ
US9810688B2 (en) * 2013-03-15 2017-11-07 Robert Bosch Gmbh Smart glass slide for microarrays
US9080196B2 (en) 2012-09-28 2015-07-14 Cilag Gmbh International System and method for determining hematocrit insensitive glucose concentration
US9005426B2 (en) 2012-09-28 2015-04-14 Cilag Gmbh International System and method for determining hematocrit insensitive glucose concentration
EP2972396A1 (en) * 2013-03-14 2016-01-20 Bayer HealthCare LLC Normalized calibration of analyte concentration determinations
WO2014140177A2 (en) * 2013-03-15 2014-09-18 Roche Diagnostics Gmbh Methods of detecting high antioxidant levels during electrochemical measurements and failsafing an analyte concentration therefrom as well as devices, apparatuses and systems incorporting the same
PL2972268T3 (pl) * 2013-03-15 2017-10-31 Hoffmann La Roche Sposoby zabezpieczenia przed błędem w elektrochemicznym pomiarze analitu, przyrządy i urządzenia oraz układy je zawierające
CN104122882A (zh) * 2013-04-24 2014-10-29 中烟机械技术中心有限责任公司 巴鲁夫自诊断型传感器的故障诊断系统
TWI567387B (zh) * 2014-09-12 2017-01-21 達爾生技股份有限公司 電化學的感測試片本身性質之異常的檢測方法
CN105445341B (zh) * 2014-09-12 2018-10-16 达尔生技股份有限公司 电化学的检测试片异常的检测方法
JP7062954B2 (ja) * 2016-02-10 2022-05-09 ソニーグループ株式会社 血液凝固解析装置及び血液凝固解析方法
EP3548881A1 (en) * 2016-12-05 2019-10-09 Ascensia Diabetes Care Holdings AG Risk factor monitoring
KR102031340B1 (ko) * 2018-03-14 2019-10-11 주식회사 필로시스 혈당 측정 장치, 방법, 및 시스템
US11382541B2 (en) * 2018-11-16 2022-07-12 Medtronic Minimed, Inc. Miniaturized analyte sensor
AU2020210303B2 (en) * 2019-08-02 2021-09-23 Bionime Corporation Micro Biosensor and Measuring Method Thereof
TWI870545B (zh) * 2020-02-21 2025-01-21 美商半導體組件工業公司 用於測量工作電極電流之方法、雙向恆電位器、及電池測量系統
CN111681713B (zh) * 2020-06-10 2023-03-31 重庆邮电大学 一种包含退相干作用的聚合物分子电学性质的模型构建方法及其应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431004A (en) 1981-10-27 1984-02-14 Bessman Samuel P Implantable glucose sensor
US4750496A (en) 1987-01-28 1988-06-14 Xienta, Inc. Method and apparatus for measuring blood glucose concentration
US5243516A (en) * 1989-12-15 1993-09-07 Boehringer Mannheim Corporation Biosensing instrument and method
US5508171A (en) 1989-12-15 1996-04-16 Boehringer Mannheim Corporation Assay method with enzyme electrode system
FR2701117B1 (fr) 1993-02-04 1995-03-10 Asulab Sa Système de mesures électrochimiques à capteur multizones, et son application au dosage du glucose.
US5366609A (en) 1993-06-08 1994-11-22 Boehringer Mannheim Corporation Biosensing meter with pluggable memory key
IE72524B1 (en) * 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
US6153069A (en) 1995-02-09 2000-11-28 Tall Oak Ventures Apparatus for amperometric Diagnostic analysis
US5582697A (en) 1995-03-17 1996-12-10 Matsushita Electric Industrial Co., Ltd. Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same
US5620579A (en) 1995-05-05 1997-04-15 Bayer Corporation Apparatus for reduction of bias in amperometric sensors
DE69809391T2 (de) 1997-02-06 2003-07-10 Therasense, Inc. Kleinvolumiger sensor zur in-vitro bestimmung
US6391645B1 (en) 1997-05-12 2002-05-21 Bayer Corporation Method and apparatus for correcting ambient temperature effect in biosensors
AU3849799A (en) * 1998-05-20 1999-12-06 Arkray, Inc. Method and apparatus for electrochemical measurement using statistical technique
JP4321966B2 (ja) * 1998-11-02 2009-08-26 アルザ・コーポレーション 適合性抗微生物剤を含有する電気輸送式デバイス
CA2305922C (en) 1999-08-02 2005-09-20 Bayer Corporation Improved electrochemical sensor design
GB0005564D0 (en) * 2000-03-08 2000-05-03 Inverness Medical Ltd Measurjement of substances in liquid
US20030235817A1 (en) * 2002-03-22 2003-12-25 Miroslaw Bartkowiak Microprocessors, devices, and methods for use in analyte monitoring systems
EP1623407A4 (en) * 2003-05-05 2011-12-21 Inventec Appliances Corp SYSTEM AND METHOD FOR GENERATING AN ANALOG SIGNAL IN ITS HAND-HELD DATA PROCESSING DEVICE
US7488601B2 (en) * 2003-06-20 2009-02-10 Roche Diagnostic Operations, Inc. System and method for determining an abused sensor during analyte measurement
US7972861B2 (en) 2004-05-14 2011-07-05 Bayer Healthcare Llc Methods for performing hematocrit adjustment in glucose assays and devices for same
CA2890945C (en) 2005-07-20 2016-11-29 Bayer Healthcare Llc Gated amperometry
KR101477948B1 (ko) 2005-09-30 2014-12-30 바이엘 헬스케어 엘엘씨 게이트형 전압 전류 측정 분석 구간 결정 방법
CA2650880C (en) * 2006-05-08 2015-11-24 Bayer Healthcare Llc Abnormal output detection system for a biosensor

Also Published As

Publication number Publication date
JP5373948B2 (ja) 2013-12-18
HK1132643A1 (en) 2010-03-05
TW200804805A (en) 2008-01-16
NO20084960L (no) 2008-11-26
WO2007133985A2 (en) 2007-11-22
CN101437443A (zh) 2009-05-20
BRPI0711433A2 (pt) 2011-11-16
US20120271559A1 (en) 2012-10-25
EP2020909A2 (en) 2009-02-11
JP2009536744A (ja) 2009-10-15
CN101437443B (zh) 2011-11-30
US9301717B2 (en) 2016-04-05
US20090099787A1 (en) 2009-04-16
RU2008148133A (ru) 2010-06-20
JP2012255803A (ja) 2012-12-27
WO2007133985A3 (en) 2008-01-10
MX2008014250A (es) 2008-11-26
US8234076B2 (en) 2012-07-31
CA2650880A1 (en) 2007-11-22
JP5121822B2 (ja) 2013-01-16
RU2465812C2 (ru) 2012-11-10
TWI431273B (zh) 2014-03-21

Similar Documents

Publication Publication Date Title
CA2650880C (en) Abnormal output detection system for a biosensor
CA2649644C (en) Underfill detection system for an electrochemical biosensor
US10724985B2 (en) Biosensor for determining a concentration of a biosensor using an underfill procedure
JP6448504B2 (ja) 勾配ベース補正
CA3044828A1 (en) Temperature adjusted analyte determination for biosensor systems
HK1132643B (en) Abnormal output detection system for a biosensor
HK1133080B (en) Underfill detection system for an electrochemical biosensor

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20210507