JP5047986B2 - 血行力学的に制御された抗頻脈性不整脈ペーシングシステム - Google Patents
血行力学的に制御された抗頻脈性不整脈ペーシングシステム Download PDFInfo
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- JP5047986B2 JP5047986B2 JP2008547229A JP2008547229A JP5047986B2 JP 5047986 B2 JP5047986 B2 JP 5047986B2 JP 2008547229 A JP2008547229 A JP 2008547229A JP 2008547229 A JP2008547229 A JP 2008547229A JP 5047986 B2 JP5047986 B2 JP 5047986B2
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- 208000001871 Tachycardia Diseases 0.000 title claims abstract description 146
- 206010049447 Tachyarrhythmia Diseases 0.000 title claims abstract description 140
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- 230000033764 rhythmic process Effects 0.000 claims abstract description 15
- 238000007726 management method Methods 0.000 claims abstract description 8
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- 238000013194 cardioversion Methods 0.000 claims description 18
- 238000011282 treatment Methods 0.000 claims description 18
- 210000001765 aortic valve Anatomy 0.000 claims description 7
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- 230000000977 initiatory effect Effects 0.000 claims 1
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- 230000034225 regulation of ventricular cardiomyocyte membrane depolarization Effects 0.000 description 19
- 206010047302 ventricular tachycardia Diseases 0.000 description 15
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/3621—Heart stimulators for treating or preventing abnormally high heart rate
- A61N1/3622—Heart stimulators for treating or preventing abnormally high heart rate comprising two or more electrodes co-operating with different heart regions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/36514—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/312,082 | 2005-12-20 | ||
| US11/312,082 US7844331B2 (en) | 2005-12-20 | 2005-12-20 | Method and apparatus for controlling anti-tachyarrhythmia pacing using hemodynamic sensor |
| PCT/US2006/043459 WO2007078421A2 (en) | 2005-12-20 | 2006-11-08 | Hemodynamically controlled anti-tachyarrhythmia pacing system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009519808A JP2009519808A (ja) | 2009-05-21 |
| JP2009519808A5 JP2009519808A5 (enExample) | 2009-12-17 |
| JP5047986B2 true JP5047986B2 (ja) | 2012-10-10 |
Family
ID=37762319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008547229A Expired - Fee Related JP5047986B2 (ja) | 2005-12-20 | 2006-11-08 | 血行力学的に制御された抗頻脈性不整脈ペーシングシステム |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7844331B2 (enExample) |
| EP (1) | EP1962955B1 (enExample) |
| JP (1) | JP5047986B2 (enExample) |
| AT (1) | ATE494923T1 (enExample) |
| DE (1) | DE602006019637D1 (enExample) |
| WO (1) | WO2007078421A2 (enExample) |
Families Citing this family (132)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7742815B2 (en) | 2005-09-09 | 2010-06-22 | Cardiac Pacemakers, Inc. | Using implanted sensors for feedback control of implanted medical devices |
| US20070142727A1 (en) * | 2005-12-15 | 2007-06-21 | Cardiac Pacemakers, Inc. | System and method for analyzing cardiovascular pressure measurements made within a human body |
| US7844331B2 (en) | 2005-12-20 | 2010-11-30 | Cardiac Pacemakers, Inc. | Method and apparatus for controlling anti-tachyarrhythmia pacing using hemodynamic sensor |
| US7761154B2 (en) * | 2006-01-25 | 2010-07-20 | Cardiac Pacemakers, Inc. | Method and apparatus for selecting and timing anti-tachyarrhythmia pacing using cardiac cycle length stability |
| US7933650B2 (en) * | 2006-02-16 | 2011-04-26 | Cardiac Pacemakers, Inc. | Method and apparatus for selecting and timing anti-tachyarrhythmia pacing using cardiac signal morphology |
| US8244337B2 (en) * | 2006-02-28 | 2012-08-14 | St. Jude Medical Ab | Method and implantable medical device for classifying sensor signals |
| US7955268B2 (en) | 2006-07-21 | 2011-06-07 | Cardiac Pacemakers, Inc. | Multiple sensor deployment |
| US8437849B2 (en) * | 2007-01-30 | 2013-05-07 | Cardiac Pacemakers, Inc. | Method and apparatus for atrial pacing during tachyarrhythmia |
| US7930022B2 (en) | 2007-05-07 | 2011-04-19 | Cardiac Pacemakers, Inc. | System and method to determine hemodynamic tolerability |
| US8131363B2 (en) * | 2007-09-25 | 2012-03-06 | Cardiac Pacemakers, Inc. | Closed-loop control of intermittent excitatory cardiac stimulation for therapeutic effect |
| US8170669B2 (en) * | 2007-10-10 | 2012-05-01 | Cardiac Pacemakers, Inc. | Method and apparatus for concurrent atrio-ventricular anti-tachycardia pacing |
| US8355782B2 (en) * | 2008-01-28 | 2013-01-15 | St. Jude Medical Ab | Implantable heart stimulator for measuring dyssynchrony using impedance |
| EP2242538B1 (en) | 2008-02-11 | 2016-04-06 | Cardiac Pacemakers, Inc. | Methods of monitoring hemodynamic status for ryhthm discrimination within the heart |
| WO2009102640A1 (en) | 2008-02-12 | 2009-08-20 | Cardiac Pacemakers, Inc. | Systems and methods for controlling wireless signal transfers between ultrasound-enabled medical devices |
| US20100331909A1 (en) * | 2008-03-31 | 2010-12-30 | Jaerverus Karin | Anti-arrhythmia implantable medical device |
| US8676303B2 (en) | 2008-05-13 | 2014-03-18 | The Regents Of The University Of California | Methods and systems for treating heart instability |
| JP5209787B2 (ja) * | 2008-06-19 | 2013-06-12 | カーディアック ペースメイカーズ, インコーポレイテッド | 血流力学耐容性分析器を有する心調律管理システム |
| WO2010042826A1 (en) | 2008-10-09 | 2010-04-15 | Sanjiv Narayan | Machine and process for the automatic localization of sources of biological rhythm disorders |
| US8591423B2 (en) | 2008-10-10 | 2013-11-26 | Cardiac Pacemakers, Inc. | Systems and methods for determining cardiac output using pulmonary artery pressure measurements |
| WO2010059291A1 (en) | 2008-11-19 | 2010-05-27 | Cardiac Pacemakers, Inc. | Assessment of pulmonary vascular resistance via pulmonary artery pressure |
| US20100280841A1 (en) * | 2009-05-04 | 2010-11-04 | Cardiac Pacemakers, Inc. | Adjudication of Arrhythmia Episode Data Systems and Methods |
| US8140156B2 (en) * | 2009-06-30 | 2012-03-20 | Medtronic, Inc. | Heart sound sensing to reduce inappropriate tachyarrhythmia therapy |
| US9332915B2 (en) | 2013-03-15 | 2016-05-10 | The Regents Of The University Of California | System and method to identify sources associated with biological rhythm disorders |
| US10398326B2 (en) | 2013-03-15 | 2019-09-03 | The Regents Of The University Of California | System and method of identifying sources associated with biological rhythm disorders |
| US9392948B2 (en) | 2011-12-09 | 2016-07-19 | The Regents Of The University Of California | System and method of identifying sources for biological rhythms |
| US10434319B2 (en) | 2009-10-09 | 2019-10-08 | The Regents Of The University Of California | System and method of identifying sources associated with biological rhythm disorders |
| US8903490B2 (en) * | 2010-03-03 | 2014-12-02 | Cardiac Pacemakers, Inc. | Methods and systems for recognizing arrhythmias using neural stimulation |
| EP2555674B1 (en) | 2010-04-08 | 2019-06-12 | The Regents of The University of California | Methods, system and apparatus for the detection, diagnosis and treatment of biological rhythm disorders |
| US8639328B2 (en) | 2010-10-29 | 2014-01-28 | Medtronic, Inc. | Cardiac therapy based upon impedance signals |
| US9061155B2 (en) * | 2010-12-23 | 2015-06-23 | Medtronic, Inc. | Implanted device data to guide ablation therapy |
| WO2012126503A1 (en) | 2011-03-18 | 2012-09-27 | St. Jude Medical Ab | Hemodynamic status assessment |
| WO2012135775A1 (en) | 2011-04-01 | 2012-10-04 | Medtronic, Inc. | Heart failure monitoring |
| US8165666B1 (en) | 2011-05-02 | 2012-04-24 | Topera, Inc. | System and method for reconstructing cardiac activation information |
| WO2012151301A1 (en) | 2011-05-02 | 2012-11-08 | Topera, Inc. | System and method for targeting heart rhythm disorders using shaped ablation |
| US20120296387A1 (en) | 2011-05-19 | 2012-11-22 | Xusheng Zhang | Phrenic nerve stimulation detection using heart sounds |
| US8617082B2 (en) | 2011-05-19 | 2013-12-31 | Medtronic, Inc. | Heart sounds-based pacing optimization |
| US8777874B2 (en) | 2011-05-24 | 2014-07-15 | Medtronic, Inc. | Acoustic based cough detection |
| US8886311B2 (en) | 2012-01-27 | 2014-11-11 | Medtronic, Inc. | Techniques for mitigating motion artifacts from implantable physiological sensors |
| US20130237872A1 (en) | 2012-03-12 | 2013-09-12 | Xusheng Zhang | Heart sound sensing to reduce inappropriate tachyarrhythmia therapy |
| US20130289378A1 (en) | 2012-04-27 | 2013-10-31 | Medtronic, Inc. | Method and apparatus for cardiac function monitoring |
| US9566442B2 (en) | 2012-11-19 | 2017-02-14 | Pacesetter, Inc. | Systems and methods for using pulmonary artery pressure from an implantable sensor to detect mitral regurgitation and optimize pacing delays |
| US9301702B2 (en) | 2012-11-19 | 2016-04-05 | Pacesetter, Inc. | Systems and methods for exploiting pulmonary artery pressure obtained from an implantable sensor to detect cardiac rhythm irregularities |
| CN104869886B (zh) * | 2012-12-13 | 2017-08-25 | 皇家飞利浦有限公司 | 用于在监测和识别对象的生理特征的异常值中使用的方法和装置 |
| WO2015088695A1 (en) * | 2013-12-10 | 2015-06-18 | Cardiac Pacemakers, Inc. | Measuring atrial fibrillation burden using implantable device based sensors |
| US9387330B2 (en) | 2014-01-17 | 2016-07-12 | Medtronic, Inc. | Cardiac resynchronization therapy optimization based on intracardiac impedance and heart sounds |
| US9199086B2 (en) | 2014-01-17 | 2015-12-01 | Medtronic, Inc. | Cardiac resynchronization therapy optimization based on intracardiac impedance |
| EP3148442B1 (en) * | 2014-06-02 | 2022-06-15 | Cardiac Pacemakers, Inc. | Apparatus for detecting atrial tachyarrhythmia using heart sounds |
| US11020095B2 (en) | 2015-01-14 | 2021-06-01 | Echosense Jersey Limited | Data compression to facilitate remote medical analysis and diagnosis |
| US20160206287A1 (en) * | 2015-01-14 | 2016-07-21 | Yoram Palti | Wearable Doppler Ultrasound Based Cardiac Monitoring |
| EP3247453B1 (en) | 2015-01-23 | 2020-11-25 | Medtronic Inc. | Atrial arrhythmia episode detection in a cardiac medical device |
| US10213125B2 (en) | 2015-01-23 | 2019-02-26 | Medtronic, Inc. | Atrial arrhythmia episode detection in a cardiac medical device |
| US10004418B2 (en) | 2015-01-23 | 2018-06-26 | Medtronic, Inc. | Atrial arrhythmia episode detection in a cardiac medical device |
| WO2016126968A1 (en) | 2015-02-06 | 2016-08-11 | Cardiac Pacemakers, Inc. | Systems and methods for safe delivery of electrical stimulation therapy |
| WO2016130477A2 (en) | 2015-02-09 | 2016-08-18 | Cardiac Pacemakers, Inc. | Implantable medical device with radiopaque id tag |
| US9901276B2 (en) | 2015-02-18 | 2018-02-27 | Medtronic, Inc. | Method and apparatus for identifying sick sinus syndrome in an implantable cardiac monitoring device |
| US9603543B2 (en) | 2015-02-18 | 2017-03-28 | Medtronic, Inc. | Method and apparatus for atrial arrhythmia episode detection |
| CN107530002B (zh) | 2015-03-04 | 2021-04-30 | 心脏起搏器股份公司 | 用于治疗心律失常的系统和方法 |
| US9853743B2 (en) | 2015-08-20 | 2017-12-26 | Cardiac Pacemakers, Inc. | Systems and methods for communication between medical devices |
| WO2017031347A1 (en) | 2015-08-20 | 2017-02-23 | Cardiac Pacemakers, Inc. | Systems and methods for communication between medical devices |
| US10226631B2 (en) | 2015-08-28 | 2019-03-12 | Cardiac Pacemakers, Inc. | Systems and methods for infarct detection |
| WO2017040115A1 (en) | 2015-08-28 | 2017-03-09 | Cardiac Pacemakers, Inc. | System for detecting tamponade |
| WO2017040153A1 (en) | 2015-08-28 | 2017-03-09 | Cardiac Pacemakers, Inc. | Systems and methods for behaviorally responsive signal detection and therapy delivery |
| US10092760B2 (en) | 2015-09-11 | 2018-10-09 | Cardiac Pacemakers, Inc. | Arrhythmia detection and confirmation |
| US10065041B2 (en) | 2015-10-08 | 2018-09-04 | Cardiac Pacemakers, Inc. | Devices and methods for adjusting pacing rates in an implantable medical device |
| US10183170B2 (en) | 2015-12-17 | 2019-01-22 | Cardiac Pacemakers, Inc. | Conducted communication in a medical device system |
| US10905886B2 (en) | 2015-12-28 | 2021-02-02 | Cardiac Pacemakers, Inc. | Implantable medical device for deployment across the atrioventricular septum |
| US10583303B2 (en) | 2016-01-19 | 2020-03-10 | Cardiac Pacemakers, Inc. | Devices and methods for wirelessly recharging a rechargeable battery of an implantable medical device |
| CN109069840B (zh) | 2016-02-04 | 2022-03-15 | 心脏起搏器股份公司 | 具有用于无引线心脏装置的力传感器的递送系统 |
| US11027132B2 (en) | 2016-03-16 | 2021-06-08 | Medtronic, Inc. | Synchronization of anti-tachycardia pacing in an extra-cardiovascular implantable system |
| US10039469B2 (en) | 2016-03-30 | 2018-08-07 | Medtronic, Inc. | Atrial arrhythmia episode detection in a cardiac medical device |
| US10045710B2 (en) | 2016-03-30 | 2018-08-14 | Medtronic, Inc. | Atrial arrhythmia episode detection in a cardiac medical device |
| US11116988B2 (en) | 2016-03-31 | 2021-09-14 | Cardiac Pacemakers, Inc. | Implantable medical device with rechargeable battery |
| US10668294B2 (en) | 2016-05-10 | 2020-06-02 | Cardiac Pacemakers, Inc. | Leadless cardiac pacemaker configured for over the wire delivery |
| US10328272B2 (en) | 2016-05-10 | 2019-06-25 | Cardiac Pacemakers, Inc. | Retrievability for implantable medical devices |
| EP3474945B1 (en) | 2016-06-27 | 2022-12-28 | Cardiac Pacemakers, Inc. | Cardiac therapy system using subcutaneously sensed p-waves for resynchronization pacing management |
| WO2018009569A1 (en) | 2016-07-06 | 2018-01-11 | Cardiac Pacemakers, Inc. | Method and system for determining an atrial contraction timing fiducial in a leadless cardiac pacemaker system |
| WO2018009392A1 (en) | 2016-07-07 | 2018-01-11 | Cardiac Pacemakers, Inc. | Leadless pacemaker using pressure measurements for pacing capture verification |
| WO2018017226A1 (en) | 2016-07-20 | 2018-01-25 | Cardiac Pacemakers, Inc. | System for utilizing an atrial contraction timing fiducial in a leadless cardiac pacemaker system |
| WO2018035343A1 (en) | 2016-08-19 | 2018-02-22 | Cardiac Pacemakers, Inc. | Trans septal implantable medical device |
| CN109640809B (zh) | 2016-08-24 | 2021-08-17 | 心脏起搏器股份公司 | 使用p波到起搏定时的集成式多装置心脏再同步治疗 |
| WO2018039322A1 (en) | 2016-08-24 | 2018-03-01 | Cardiac Pacemakers, Inc. | Cardiac resynchronization using fusion promotion for timing management |
| WO2018057318A1 (en) | 2016-09-21 | 2018-03-29 | Cardiac Pacemakers, Inc. | Leadless stimulation device with a housing that houses internal components of the leadless stimulation device and functions as the battery case and a terminal of an internal battery |
| US10758737B2 (en) | 2016-09-21 | 2020-09-01 | Cardiac Pacemakers, Inc. | Using sensor data from an intracardially implanted medical device to influence operation of an extracardially implantable cardioverter |
| WO2018057626A1 (en) | 2016-09-21 | 2018-03-29 | Cardiac Pacemakers, Inc. | Implantable cardiac monitor |
| WO2018081017A1 (en) | 2016-10-27 | 2018-05-03 | Cardiac Pacemakers, Inc. | Implantable medical device with pressure sensor |
| US10463305B2 (en) | 2016-10-27 | 2019-11-05 | Cardiac Pacemakers, Inc. | Multi-device cardiac resynchronization therapy with timing enhancements |
| WO2018081225A1 (en) | 2016-10-27 | 2018-05-03 | Cardiac Pacemakers, Inc. | Implantable medical device delivery system with integrated sensor |
| WO2018081133A1 (en) | 2016-10-27 | 2018-05-03 | Cardiac Pacemakers, Inc. | Implantable medical device having a sense channel with performance adjustment |
| WO2018081237A1 (en) | 2016-10-27 | 2018-05-03 | Cardiac Pacemakers, Inc. | Use of a separate device in managing the pace pulse energy of a cardiac pacemaker |
| US10413733B2 (en) | 2016-10-27 | 2019-09-17 | Cardiac Pacemakers, Inc. | Implantable medical device with gyroscope |
| WO2018081713A1 (en) | 2016-10-31 | 2018-05-03 | Cardiac Pacemakers, Inc | Systems for activity level pacing |
| US10434317B2 (en) | 2016-10-31 | 2019-10-08 | Cardiac Pacemakers, Inc. | Systems and methods for activity level pacing |
| US10583301B2 (en) | 2016-11-08 | 2020-03-10 | Cardiac Pacemakers, Inc. | Implantable medical device for atrial deployment |
| WO2018089308A1 (en) | 2016-11-09 | 2018-05-17 | Cardiac Pacemakers, Inc. | Systems, devices, and methods for setting cardiac pacing pulse parameters for a cardiac pacing device |
| US10881869B2 (en) | 2016-11-21 | 2021-01-05 | Cardiac Pacemakers, Inc. | Wireless re-charge of an implantable medical device |
| US10639486B2 (en) | 2016-11-21 | 2020-05-05 | Cardiac Pacemakers, Inc. | Implantable medical device with recharge coil |
| WO2018094342A1 (en) | 2016-11-21 | 2018-05-24 | Cardiac Pacemakers, Inc | Implantable medical device with a magnetically permeable housing and an inductive coil disposed about the housing |
| EP3541471B1 (en) | 2016-11-21 | 2021-01-20 | Cardiac Pacemakers, Inc. | Leadless cardiac pacemaker providing cardiac resynchronization therapy |
| EP3541473B1 (en) | 2016-11-21 | 2020-11-11 | Cardiac Pacemakers, Inc. | Leadless cardiac pacemaker with multimode communication |
| US11207532B2 (en) | 2017-01-04 | 2021-12-28 | Cardiac Pacemakers, Inc. | Dynamic sensing updates using postural input in a multiple device cardiac rhythm management system |
| US10835753B2 (en) | 2017-01-26 | 2020-11-17 | Cardiac Pacemakers, Inc. | Intra-body device communication with redundant message transmission |
| WO2018140623A1 (en) | 2017-01-26 | 2018-08-02 | Cardiac Pacemakers, Inc. | Leadless device with overmolded components |
| US10737102B2 (en) | 2017-01-26 | 2020-08-11 | Cardiac Pacemakers, Inc. | Leadless implantable device with detachable fixation |
| US10905872B2 (en) | 2017-04-03 | 2021-02-02 | Cardiac Pacemakers, Inc. | Implantable medical device with a movable electrode biased toward an extended position |
| US10821288B2 (en) | 2017-04-03 | 2020-11-03 | Cardiac Pacemakers, Inc. | Cardiac pacemaker with pacing pulse energy adjustment based on sensed heart rate |
| WO2019036568A1 (en) | 2017-08-18 | 2019-02-21 | Cardiac Pacemakers, Inc. | IMPLANTABLE MEDICAL DEVICE COMPRISING A FLOW CONCENTRATOR AND A RECEPTION COIL PROVIDED AROUND THE FLOW CONCENTRATOR |
| EP3668592B1 (en) | 2017-08-18 | 2021-11-17 | Cardiac Pacemakers, Inc. | Implantable medical device with pressure sensor |
| US11235163B2 (en) | 2017-09-20 | 2022-02-01 | Cardiac Pacemakers, Inc. | Implantable medical device with multiple modes of operation |
| US11185703B2 (en) | 2017-11-07 | 2021-11-30 | Cardiac Pacemakers, Inc. | Leadless cardiac pacemaker for bundle of his pacing |
| CN111417433B (zh) | 2017-12-01 | 2024-04-30 | 心脏起搏器股份公司 | 从心室植入的无引线心脏起搏器检测心室充盈期间心房收缩定时基准的方法和系统 |
| CN111432874A (zh) | 2017-12-01 | 2020-07-17 | 心脏起搏器股份公司 | 从心室植入的无引线心脏起搏器检测搜索窗口内心房收缩定时基准的方法和系统 |
| EP3717063B1 (en) | 2017-12-01 | 2023-12-27 | Cardiac Pacemakers, Inc. | Systems for detecting atrial contraction timing fiducials and determining a cardiac interval from a ventricularly implanted leadless cardiac pacemaker |
| CN111417432B (zh) | 2017-12-01 | 2024-04-30 | 心脏起搏器股份公司 | 具有复归行为的无引线心脏起搏器 |
| US11529523B2 (en) | 2018-01-04 | 2022-12-20 | Cardiac Pacemakers, Inc. | Handheld bridge device for providing a communication bridge between an implanted medical device and a smartphone |
| CN111556773A (zh) | 2018-01-04 | 2020-08-18 | 心脏起搏器股份公司 | 无逐搏通信的双腔起搏 |
| US11235159B2 (en) | 2018-03-23 | 2022-02-01 | Medtronic, Inc. | VFA cardiac resynchronization therapy |
| US11058880B2 (en) | 2018-03-23 | 2021-07-13 | Medtronic, Inc. | VFA cardiac therapy for tachycardia |
| WO2019183507A1 (en) | 2018-03-23 | 2019-09-26 | Medtronic, Inc. | Av synchronous vfa cardiac therapy |
| WO2020065582A1 (en) | 2018-09-26 | 2020-04-02 | Medtronic, Inc. | Capture in ventricle-from-atrium cardiac therapy |
| US11951313B2 (en) | 2018-11-17 | 2024-04-09 | Medtronic, Inc. | VFA delivery systems and methods |
| US12296177B2 (en) | 2018-12-21 | 2025-05-13 | Medtronic, Inc. | Delivery systems and methods for left ventricular pacing |
| US11207536B2 (en) | 2019-01-09 | 2021-12-28 | Cardiac Pacemakers, Inc. | Method and apparatus for enhancing atrial fibrillation detection |
| US11679265B2 (en) | 2019-02-14 | 2023-06-20 | Medtronic, Inc. | Lead-in-lead systems and methods for cardiac therapy |
| US11697025B2 (en) | 2019-03-29 | 2023-07-11 | Medtronic, Inc. | Cardiac conduction system capture |
| US11213676B2 (en) | 2019-04-01 | 2022-01-04 | Medtronic, Inc. | Delivery systems for VfA cardiac therapy |
| US11712188B2 (en) | 2019-05-07 | 2023-08-01 | Medtronic, Inc. | Posterior left bundle branch engagement |
| US11305127B2 (en) | 2019-08-26 | 2022-04-19 | Medtronic Inc. | VfA delivery and implant region detection |
| US11813466B2 (en) | 2020-01-27 | 2023-11-14 | Medtronic, Inc. | Atrioventricular nodal stimulation |
| US11911168B2 (en) | 2020-04-03 | 2024-02-27 | Medtronic, Inc. | Cardiac conduction system therapy benefit determination |
| US11813464B2 (en) | 2020-07-31 | 2023-11-14 | Medtronic, Inc. | Cardiac conduction system evaluation |
| US12465770B2 (en) | 2020-07-31 | 2025-11-11 | Medtronic, Inc. | Coronary sinus conduction system pacing and delivery |
| WO2025136640A1 (en) * | 2023-12-22 | 2025-06-26 | Tc1 Llc | Systems and methods for wavelet transformation based dicrotic notch extraction and arrhythmia detection |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4137910A (en) * | 1976-09-30 | 1979-02-06 | Murphy Donald H | Method and means for measuring cardiac pumping performance of left ventricle |
| US4830006B1 (en) * | 1986-06-17 | 1997-10-28 | Intermedics Inc | Implantable cardiac stimulator for detection and treatment of ventricular arrhythmias |
| DE3732640C1 (de) | 1987-09-28 | 1989-05-18 | Alt Eckhard | Medizinisches Geraet zum Ermitteln von physiologischen Funktionsparametern |
| US4774950A (en) * | 1987-10-06 | 1988-10-04 | Leonard Bloom | Hemodynamically responsive system for and method of treating a malfunctioning heart |
| US5163429A (en) * | 1987-10-06 | 1992-11-17 | Leonard Bloom | Hemodynamically responsive system for treating a malfunctioning heart |
| US5183040A (en) * | 1991-03-08 | 1993-02-02 | Telectronics Pacing Systems, Inc. | Apparatus and method for detecting abnormal cardiac rhythms using an ultrasound sensor in an arrhythmia control system |
| US5282840A (en) * | 1992-03-26 | 1994-02-01 | Medtronic, Inc. | Multiple frequency impedance measurement system |
| US5370667A (en) * | 1992-04-03 | 1994-12-06 | Intermedics, Inc. | Device and method for automatically adjusting tachycardia recognition criteria based on detected parameter |
| US5330505A (en) * | 1992-05-08 | 1994-07-19 | Leonard Bloom | System for and method of treating a malfunctioning heart |
| US5311874A (en) * | 1992-05-18 | 1994-05-17 | Cardiac Pacemakers, Inc. | Method for tachycardia discrimination |
| US5390679A (en) * | 1993-06-03 | 1995-02-21 | Eli Lilly And Company | Continuous cardiac output derived from the arterial pressure waveform using pattern recognition |
| HRP940035A2 (en) | 1994-01-24 | 1996-10-31 | Bozidar Ferek Petric | Cardiac electrotherapy system synchronized with a venous flow |
| WO1995020348A1 (en) | 1994-01-28 | 1995-08-03 | Ep Technologies, Inc. | Matching electrical characteristics and propagation velocities to locate ablation sites |
| US5788717A (en) * | 1995-07-11 | 1998-08-04 | Pacesetter, Inc. | Atrial rate determination and atrial tachycardia detection in a dual-chamber implantable pacemaker |
| US5978707A (en) * | 1997-04-30 | 1999-11-02 | Cardiac Pacemakers, Inc. | Apparatus and method for treating ventricular tachyarrhythmias |
| US5897575A (en) * | 1997-10-24 | 1999-04-27 | Pacesetter, Inc. | Arrhythmia classification system with reliability indication that allows for low quality input signals in pacemakers |
| SE9800040D0 (sv) * | 1998-01-09 | 1998-01-09 | Pacesetter Ab | A heart stimulator |
| US6101414A (en) * | 1998-02-11 | 2000-08-08 | Pacesetter, Inc. | Method and apparatus for antitachycardia pacing with an optimal coupling interval |
| US5999854A (en) * | 1998-04-14 | 1999-12-07 | Intermedics Inc. | Implantable cardiac stimulator with physiologic sensor based on mechanical-electric phase relation |
| US6217525B1 (en) * | 1998-04-30 | 2001-04-17 | Medtronic Physio-Control Manufacturing Corp. | Reduced lead set device and method for detecting acute cardiac ischemic conditions |
| US6044298A (en) * | 1998-10-13 | 2000-03-28 | Cardiac Pacemakers, Inc. | Optimization of pacing parameters based on measurement of integrated acoustic noise |
| US6278894B1 (en) * | 1999-06-21 | 2001-08-21 | Cardiac Pacemakers, Inc. | Multi-site impedance sensor using coronary sinus/vein electrodes |
| US6493579B1 (en) * | 1999-08-20 | 2002-12-10 | Cardiac Pacemakers, Inc. | System and method for detection enhancement programming |
| US6522925B1 (en) * | 2000-05-13 | 2003-02-18 | Cardiac Pacemakers, Inc. | System and method for detection enhancement programming |
| US6522914B1 (en) * | 2000-07-14 | 2003-02-18 | Cardiac Pacemakers, Inc. | Method and apparatuses for monitoring hemodynamic activities using an intracardiac impedance-derived parameter |
| US6708058B2 (en) * | 2001-04-30 | 2004-03-16 | Cardiac Pacemakers, Inc. | Normal cardiac rhythm template generation system and method |
| US6873870B2 (en) * | 2001-04-30 | 2005-03-29 | Medtronic, Inc. | Methods for adjusting cardiac detection criteria and implantable medical devices using same |
| US6654639B1 (en) * | 2001-05-07 | 2003-11-25 | Pacesetter, Inc. | Method and device for multi-chamber cardiac pacing in response to a tachycardia |
| US6775572B2 (en) * | 2001-10-25 | 2004-08-10 | Cardiac Pacemakers, Inc. | Method and system for automatic anti-tachycardia pacing |
| US6885890B2 (en) * | 2001-12-20 | 2005-04-26 | Cardiac Pacemakers, Inc. | Apparatus and method for multi-site anti-tachycardia pacing |
| US7010344B2 (en) | 2002-04-26 | 2006-03-07 | Medtronic, Inc. | Method and apparatus for delaying a ventricular tachycardia therapy |
| US7113825B2 (en) * | 2002-05-03 | 2006-09-26 | Cardiac Pacemakers, Inc. | Method and apparatus for detecting acoustic oscillations in cardiac rhythm |
| SE0202290D0 (sv) | 2002-07-22 | 2002-07-22 | St Jude Medical | Monitor |
| WO2004091719A2 (en) * | 2003-04-11 | 2004-10-28 | Cardiac Pacemakers, Inc. | Multi-parameter arrhythmia discrimination |
| US7218966B2 (en) * | 2003-04-11 | 2007-05-15 | Cardiac Pacemakers, Inc. | Multi-parameter arrhythmia discrimination |
| US7149573B2 (en) * | 2003-04-25 | 2006-12-12 | Medtronic, Inc. | Method and apparatus for impedance signal localizations from implanted devices |
| US20040220636A1 (en) * | 2003-04-29 | 2004-11-04 | Medtronic, Inc. | Cardiac pacing therapy parameter programming |
| US7177683B2 (en) * | 2003-04-30 | 2007-02-13 | Medtronic, Inc. | History-dependent pacing interval determination for antitachycardia pacing |
| US7130681B2 (en) * | 2003-05-09 | 2006-10-31 | Medtronic, Inc. | Use of accelerometer signal to augment ventricular arrhythmia detection |
| WO2004105862A2 (en) * | 2003-05-28 | 2004-12-09 | The Ohio State University | Measuring human heart muscle viability using myocardial electrical impedance |
| EP1651310B1 (en) * | 2003-07-28 | 2007-01-24 | Medtronic, Inc. | Myocardial stimulation |
| US7010347B2 (en) * | 2004-02-14 | 2006-03-07 | Pacesetter, Inc. | Optimization of impedance signals for closed loop programming of cardiac resynchronization therapy devices |
| EP1510173B1 (de) * | 2003-09-01 | 2017-04-05 | BIOTRONIK SE & Co. KG | Intrakardiale Impedanzmessanordnung |
| US7239915B2 (en) * | 2003-12-16 | 2007-07-03 | Medtronic, Inc. | Hemodynamic optimization system for biventricular implants |
| US7272443B2 (en) | 2004-03-26 | 2007-09-18 | Pacesetter, Inc. | System and method for predicting a heart condition based on impedance values using an implantable medical device |
| US7277750B2 (en) * | 2004-04-02 | 2007-10-02 | Cardiac Pacemakers, Inc. | Method and apparatus for anti-tachycardia pacing and defibrillation |
| US7228173B2 (en) * | 2004-11-23 | 2007-06-05 | Cardiac Pacemakers, Inc. | Cardiac tachyarrhythmia therapy selection based on patient response information |
| DE602004027848D1 (de) | 2004-10-11 | 2010-08-05 | St Jude Medical | Nachweis von ischämie |
| US20060122651A1 (en) * | 2004-12-03 | 2006-06-08 | Whitman Teresa A | Use of mechanical restitution to predict hemodynamic response to a rapid ventricular rhythm |
| US7447543B2 (en) | 2005-02-15 | 2008-11-04 | Regents Of The University Of Minnesota | Pathology assessment with impedance measurements using convergent bioelectric lead fields |
| US7283871B1 (en) * | 2005-04-07 | 2007-10-16 | Pacesetter, Inc. | Self adjusting optimal waveforms |
| US8494618B2 (en) * | 2005-08-22 | 2013-07-23 | Cardiac Pacemakers, Inc. | Intracardiac impedance and its applications |
| US7702384B2 (en) * | 2005-12-13 | 2010-04-20 | Cardiac Pacemakers, Inc. | Zoneless tachyarrhythmia detection with real-time rhythm monitoring |
| US7844331B2 (en) | 2005-12-20 | 2010-11-30 | Cardiac Pacemakers, Inc. | Method and apparatus for controlling anti-tachyarrhythmia pacing using hemodynamic sensor |
| US7582061B2 (en) * | 2005-12-22 | 2009-09-01 | Cardiac Pacemakers, Inc. | Method and apparatus for morphology-based arrhythmia classification using cardiac and other physiological signals |
| US7761154B2 (en) * | 2006-01-25 | 2010-07-20 | Cardiac Pacemakers, Inc. | Method and apparatus for selecting and timing anti-tachyarrhythmia pacing using cardiac cycle length stability |
| US7756578B2 (en) | 2006-02-17 | 2010-07-13 | Cardiac Pacemakers, Inc. | Rhythm discrimination of sudden onset and one-to-one tachyarrythmia |
| US7848808B2 (en) * | 2006-02-28 | 2010-12-07 | Medtronic, Inc. | System and method for delivery of cardiac pacing in a medical device in response to ischemia |
| US7930022B2 (en) | 2007-05-07 | 2011-04-19 | Cardiac Pacemakers, Inc. | System and method to determine hemodynamic tolerability |
| JP5209787B2 (ja) * | 2008-06-19 | 2013-06-12 | カーディアック ペースメイカーズ, インコーポレイテッド | 血流力学耐容性分析器を有する心調律管理システム |
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