JP5031132B2 - Ｔｒａｉｌに結合する受容体 - Google Patents

Ｔｒａｉｌに結合する受容体 Download PDF

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Publication number
JP5031132B2
JP5031132B2 JP53582098A JP53582098A JP5031132B2 JP 5031132 B2 JP5031132 B2 JP 5031132B2 JP 53582098 A JP53582098 A JP 53582098A JP 53582098 A JP53582098 A JP 53582098A JP 5031132 B2 JP5031132 B2 JP 5031132B2
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JP
Japan
Prior art keywords
trail
protein
polypeptide
cells
seq
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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JP53582098A
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English (en)
Japanese (ja)
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JP2002514069A (ja
JP2002514069A5 (https=
Inventor
ローチ，チャールズ
ワルクサック，ヘニング
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Immunex Corp
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Immunex Corp
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27542220&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP5031132(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunex Corp filed Critical Immunex Corp
Publication of JP2002514069A publication Critical patent/JP2002514069A/ja
Publication of JP2002514069A5 publication Critical patent/JP2002514069A5/ja
Application granted granted Critical
Publication of JP5031132B2 publication Critical patent/JP5031132B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP53582098A 1997-02-13 1998-02-11 Ｔｒａｉｌに結合する受容体 Expired - Lifetime JP5031132B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US79986197A 1997-02-13 1997-02-13
US08/799,861 1997-02-13
US81525597A 1997-03-12 1997-03-12
US08/815,255 1997-03-12
US82953697A 1997-03-28 1997-03-28
US08/829,536 1997-03-28
US86985297A 1997-06-04 1997-06-04
US08/869,852 1997-06-04
US08/883,036 US6072047A (en) 1997-02-13 1997-06-26 Receptor that binds trail
US08/883,036 1997-06-26
PCT/US1998/002239 WO1998035986A1 (en) 1997-02-13 1998-02-11 Receptor that binds trail

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009219686A Division JP5334773B6 (ja) 1997-02-13 2009-09-24 Ｔｒａｉｌに結合する受容体

Publications (3)

Publication Number Publication Date
JP2002514069A JP2002514069A (ja) 2002-05-14
JP2002514069A5 JP2002514069A5 (https=) 2005-07-14
JP5031132B2 true JP5031132B2 (ja) 2012-09-19

Family

ID=27542220

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53582098A Expired - Lifetime JP5031132B2 (ja) 1997-02-13 1998-02-11 Ｔｒａｉｌに結合する受容体

Country Status (12)

Country Link
US (3) US6072047A (https=)
EP (2) EP1005488B9 (https=)
JP (1) JP5031132B2 (https=)
AT (1) ATE308561T1 (https=)
AU (1) AU735686B2 (https=)
CA (1) CA2279838A1 (https=)
DE (1) DE69832178T3 (https=)
DK (1) DK1005488T4 (https=)
ES (1) ES2251767T5 (https=)
IL (2) IL131030A0 (https=)
NZ (1) NZ336929A (https=)
WO (1) WO1998035986A1 (https=)

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US6872568B1 (en) 1997-03-17 2005-03-29 Human Genome Sciences, Inc. Death domain containing receptor 5 antibodies
CN1624128A (zh) 1997-03-17 2005-06-08 人类基因组科学公司 包含死亡结构域的受体－5
US20080248046A1 (en) * 1997-03-17 2008-10-09 Human Genome Sciences, Inc. Death domain containing receptor 5
US20050233958A1 (en) * 1997-03-17 2005-10-20 Human Genome Sciences, Inc. Death domain containing receptor 5
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CN101289511A (zh) 2000-04-11 2008-10-22 杰南技术公司 多价抗体及其应用
US7476383B2 (en) * 2000-05-02 2009-01-13 The Uab Research Foundation Antibody selective for DR4 and uses thereof
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US7279160B2 (en) * 2000-05-02 2007-10-09 The Uab Research Foundation Combinations of DR5 antibodies and other therapeutic agents
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Also Published As

Publication number Publication date
ES2251767T5 (es) 2012-03-07
EP1005488B2 (en) 2011-12-14
DE69832178T2 (de) 2006-07-20
EP1676857A2 (en) 2006-07-05
WO1998035986A1 (en) 1998-08-20
EP1005488A1 (en) 2000-06-07
ES2251767T9 (es) 2012-10-17
EP1005488B1 (en) 2005-11-02
EP1005488A4 (en) 2003-03-05
DE69832178D1 (de) 2005-12-08
EP1676857A3 (en) 2007-04-04
JP2002514069A (ja) 2002-05-14
CA2279838A1 (en) 1998-08-20
US6072047A (en) 2000-06-06
IL131030A0 (en) 2001-01-28
US6642358B1 (en) 2003-11-04
EP1005488B9 (en) 2012-04-18
AU735686B2 (en) 2001-07-12
AU6650598A (en) 1998-09-08
DK1005488T3 (da) 2006-03-06
NZ336929A (en) 2000-11-24
DE69832178T3 (de) 2012-03-29
HK1029796A1 (en) 2001-04-12
ES2251767T3 (es) 2006-05-01
ATE308561T1 (de) 2005-11-15
US6569642B1 (en) 2003-05-27
IL131030A (en) 2011-02-28
DK1005488T4 (da) 2012-01-16

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