JP4994374B2 - がんを治療するための化合物および方法 - Google Patents

がんを治療するための化合物および方法 Download PDF

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Publication number
JP4994374B2
JP4994374B2 JP2008524273A JP2008524273A JP4994374B2 JP 4994374 B2 JP4994374 B2 JP 4994374B2 JP 2008524273 A JP2008524273 A JP 2008524273A JP 2008524273 A JP2008524273 A JP 2008524273A JP 4994374 B2 JP4994374 B2 JP 4994374B2
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Japan
Prior art keywords
compound
alkyl
cancer
pharmaceutical composition
aralkyl
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JP2008524273A
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English (en)
Japanese (ja)
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JP2009502971A (ja
JP2009502971A5 (https=
Inventor
ポール ガッチ，
ブライアン レンゼルマン，
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Ziopharm Oncology Inc
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Ziopharm Oncology Inc
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Publication of JP2009502971A publication Critical patent/JP2009502971A/ja
Publication of JP2009502971A5 publication Critical patent/JP2009502971A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/285—Arsenic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/66—Arsenic compounds
    • C07F9/70—Organo-arsenic compounds
    • C07F9/72—Aliphatic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2008524273A 2005-07-29 2006-07-28 がんを治療するための化合物および方法 Active JP4994374B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70416305P 2005-07-29 2005-07-29
US60/704,163 2005-07-29
PCT/US2006/029835 WO2007027344A2 (en) 2005-07-29 2006-07-28 Compounds and methods for the treatment of cancer

Publications (3)

Publication Number Publication Date
JP2009502971A JP2009502971A (ja) 2009-01-29
JP2009502971A5 JP2009502971A5 (https=) 2011-09-22
JP4994374B2 true JP4994374B2 (ja) 2012-08-08

Family

ID=37809342

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008524273A Active JP4994374B2 (ja) 2005-07-29 2006-07-28 がんを治療するための化合物および方法

Country Status (8)

Country Link
US (3) US7968738B2 (https=)
EP (2) EP1919564B1 (https=)
JP (1) JP4994374B2 (https=)
AU (1) AU2006285329B2 (https=)
CA (1) CA2617049A1 (https=)
ES (2) ES2532666T3 (https=)
NO (1) NO20081045L (https=)
WO (1) WO2007027344A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2532666T3 (es) 2005-07-29 2015-03-30 Solasia Pharma K.K. Compuestos y métodos para el tratamiento del cáncer
TW200829261A (en) 2006-09-29 2008-07-16 Ziopharm Oncology Inc Method for controlling angiogenesis in animals
KR20100100835A (ko) 2007-11-02 2010-09-15 지오팜 온콜로지 인코포레이티드 유기 비소제와의 병용 요법
SG186599A1 (en) * 2007-12-12 2013-01-30 Ziopharm Oncology Inc Compounds and methods for the treatment of cancer
RU2534606C2 (ru) * 2008-08-20 2014-11-27 Зайофарм Онколоджи, Инк. Мышьякорганические соединения и способы лечения рака
WO2014045083A1 (en) 2012-09-20 2014-03-27 Bendale Yogesh Narayan Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancers
TWI617305B (zh) * 2013-12-05 2018-03-11 蘇愛康制藥有限公司 治療癌症的化合物及其應用程序
BR112017018772B1 (pt) * 2015-03-12 2021-09-21 Km Biologics Co., Ltd. Material antiadesão, método para a preparação e kit do referido material e biomembrana substituta, método para a preparação e kit da referida membrana
CN107167433A (zh) * 2016-03-07 2017-09-15 天津国际生物医药联合研究院 一种检测氯二甲基砷的方法
JPWO2019220961A1 (ja) * 2018-05-18 2020-05-28 ソレイジア・ファーマ株式会社 ダリナパルシンのアルカリ金属塩及び／又は無機酸付加塩の結晶型及びその製剤

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277819B1 (en) * 1996-08-30 2001-08-21 Eli Lilly And Company Use of GLP-1 or analogs in treatment of myocardial infarction
JP2001519366A (ja) * 1997-10-15 2001-10-23 ポーラクス バイオファーマシュティカルズ，インコーポレーテッド ヒ素化合物を用いた、原発性および転移性の腫瘍性疾患を治療するための組成物および方法
IL136051A0 (en) * 1997-11-10 2001-05-20 Sloan Kettering Inst Cancer Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol
JP2001525371A (ja) * 1997-12-05 2001-12-11 イーライ・リリー・アンド・カンパニー Ｇｌｐ−１製剤
CN1233476A (zh) * 1998-04-24 1999-11-03 陆道培 治疗急性白血病的药物及其制备方法
SE9802080D0 (sv) * 1998-06-11 1998-06-11 Hellstroem Pharmaceutical composition for the treatment of functional dyspepsia and/or irritable bowel syndrome and new use of substances therein
EP1002537A1 (en) 1998-10-30 2000-05-24 Assistance Publique, Hopitaux De Paris Use of melarsoprol for the manufacture of a medicament for treating B-cell lymphoproliferative diseases, such as multiple myeloma
US6191123B1 (en) * 1999-03-19 2001-02-20 Parker Hughes Institute Organic-arsenic compounds
EP1328253B1 (en) * 2000-04-26 2006-03-22 Oregon Health Sciences University Administration of a thiol-based chemoprotectant compound
US6911471B2 (en) 2002-01-07 2005-06-28 The Texas A&M University System S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer
TWI411431B (zh) * 2004-07-16 2013-10-11 Texas A & M Univ Sys 有機砷化合物、其用於治療癌症之用途及包含其之醫藥組成物
ES2532666T3 (es) 2005-07-29 2015-03-30 Solasia Pharma K.K. Compuestos y métodos para el tratamiento del cáncer
KR20100100835A (ko) * 2007-11-02 2010-09-15 지오팜 온콜로지 인코포레이티드 유기 비소제와의 병용 요법

Also Published As

Publication number Publication date
EP1919564A2 (en) 2008-05-14
US8334398B2 (en) 2012-12-18
EP2394702B1 (en) 2014-12-31
AU2006285329A1 (en) 2007-03-08
WO2007027344A2 (en) 2007-03-08
AU2006285329B2 (en) 2012-10-04
US20130142730A1 (en) 2013-06-06
JP2009502971A (ja) 2009-01-29
WO2007027344A3 (en) 2007-12-21
EP1919564B1 (en) 2014-11-26
ES2531159T3 (es) 2015-03-11
HK1164767A1 (en) 2012-09-28
AU2006285329A2 (en) 2008-08-14
CA2617049A1 (en) 2007-03-08
US20120022229A1 (en) 2012-01-26
US7968738B2 (en) 2011-06-28
EP2394702A1 (en) 2011-12-14
ES2532666T3 (es) 2015-03-30
HK1117780A1 (en) 2009-01-23
US8865764B2 (en) 2014-10-21
US20070183972A1 (en) 2007-08-09
NO20081045L (no) 2008-04-25

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US8865764B2 (en) Compounds and methods for the treatment of cancer
US11324713B2 (en) Organoarsenic compounds and methods for the treatment of cancer
JP5202332B2 (ja) がんの治療のための化合物および方法
TWI617305B (zh) 治療癌症的化合物及其應用程序
HK1164767B (en) Compounds and methods for the treatment of cancer
HK1117780B (en) Compounds and methods for the treatment of cancer
HK1228370A1 (en) Compounds and methods for the treatment of cancer
AU2013273809A1 (en) Compounds and methods for the treatment of cancer

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