JP4991200B2 - Solubilized cosmetics - Google Patents

Description

  The present invention relates to a cosmetic, and more particularly to a solubilized cosmetic such as a lotion containing a specific surfactant and a polyhydric alcohol.

  A solubilizer is used in skin lotions and the like in order to stably incorporate water-insoluble substances such as fragrances, oils, and oil-soluble drugs. Typical existing solubilizers include polyethylene glycol hydrogenated castor oil, polyoxyethylene alkyl ether, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyethylene glycol fatty acid ester, polyoxyethylene polyoxypropylene alkyl ether, and the like. However, it was not fully satisfactory in terms of solubilizing ability, and the ester structure product could possibly undergo hydrolysis over time. In addition, solubilized cosmetics using these solubilizers are usually mixed with polyhydric alcohol to moisturize the skin, but have a problem of stickiness.

In order to solve these problems, a method using a branched fatty acid polyglycoside as a solubilizer (see Patent Document 1), a method using a polyglycerin fatty acid ester (see Patent Document 2), a water-soluble cross-linked amphiphilic polymer A method using an electrolyte (see Patent Document 3), a method using a terpene alcohol ethoxylate (see Patent Document 4), and the like are performed.
JP 9-31592 A JP 2001-232174 A JP-A-9-40584 JP2002-193837

  The present invention relates to a solubilized cosmetic comprising a solubilizing agent that has excellent solubilizing ability and good stability and can reduce the stickiness of polyhydric alcohol.

［式中、Ｒはフィトステロール残基、ｍは平均付加モル数で５〜３０の数を示し、ｎは平均付加モル数で１０〜５０の数を示す。］ で表されるフィトステロールのポリオキシプロピレンおよびポリオキシエチレン付加物よりなる非イオン界面活性剤、すなわちＰＯＰ（５〜３０）ＰＯＥ（１０〜５０）フィトステリルエーテルの１種または２種以上、
及び（Ｂ）１，３−ブチレングリコール、ジプロピレングリコール、グリセリンおよびソルビトールから選ばれる多価アルコールの１種または２種以上、を配合することにより課題を解決することが出来ることを見出した。 As a result of intensive studies in view of the circumstances, the present inventors have determined that (A) the general formula (1)

[Wherein, R represents a phytosterol residue, m represents an average added mole number of 5 to 30, and n represents an average added mole number of 10 to 50. ] A nonionic surfactant comprising a polyoxypropylene and a polyoxyethylene adduct of phytosterol represented by: one or more of POP (5-30) POE (10-50) phytosteryl ether,
And (B) It discovered that a subject could be solved by mix | blending 1 type, or 2 or more types of the polyhydric alcohol chosen from 1, 3- butylene glycol, dipropylene glycol, glycerol, and sorbitol.

  In cosmetics containing water-insoluble substances such as fragrances, oils, and oil-soluble drugs, the stickiness of polyhydric alcohol is reduced and solubilized by blending the specific nonionic surfactant and polyhydric alcohol. A solubilized cosmetic composition having excellent performance and stability can be obtained.

  Solubilizers blended with solubilized cosmetics containing water-insoluble substances such as fragrances, oils, and oil-soluble drugs are synthesized by adding polyoxypropylene and polyoxyethylene to phytosterols. It can be obtained from a gum obtained in the deoxidation step of vegetable oil such as bean oil. Phytosterol is not a single compound but a mixture mainly composed of β-sitosterol, stigmasterol, campesterol, and the like. These compounds may be isolated, but may be used as a mixture. This addition reaction of polyoxypropylene and polyoxyethylene to phytosterol can be carried out by a conventional method. The average added mole number of polyoxypropylene is 5 to 30 moles, and the average added mole number of polyoxyethylene is preferably 10 to 50 moles.

  The solubilized cosmetic composition of the present invention contains 0.01 to 20.0% by mass, preferably 0.05 to 10.0% by mass, of a nonionic surfactant comprising phytosterol polyoxypropylene and a polyoxyethylene adduct. To do.

  The solubilized cosmetic composition of the present invention contains one or more polyhydric alcohols selected from 1,3-butylene glycol, dipropylene glycol, glycerin and sorbitol as a humectant. These humectants are blended in the total amount of the solubilized cosmetic in an amount of 2.0 to 30.0% by mass, preferably 5.0 to 20.0% by mass.

  In the solubilized cosmetic of the present invention, (A) a nonionic surfactant comprising a polyoxypropylene and polyoxyethylene adduct of phytosterol, and (B) 1,3-butylene glycol, dipropylene glycol, glycerin and sorbitol The mass ratio (A) / (B) of one or more polyhydric alcohols to be selected is not particularly limited, but is preferably 1/100 to 1/1, and more preferably 1/50 to 1 /. 2.

  In the solubilized cosmetic of the present invention, surfactants other than the above components, oils, humectants, thickeners, water-soluble polyhydric alcohols, pH adjustment, which are generally blended in cosmetics and quasi drugs, etc. You may mix | blend other components, such as an agent, a chelating agent, a chemical | medical agent, a ultraviolet absorber, a ultraviolet-ray scattering agent, a fragrance | flavor, a pigment, and dye. Those components may be blended one by one or two or more.

  In addition, the solubilized cosmetic composition of the present invention may be blended with various vitamins and medicinal ingredients which are physiologically active substances often blended in cosmetics and quasi drugs. Examples of such physiologically active substances include vitamin C, vitamin C phosphate ester magnesium, vitamin C stearate ester, vitamin C palmitate ester, vitamin C dipalmitate ester, vitamin C tetraisopalmitate ester, ascorbic acid Whitening agents such as glucose, arbutin, ellagic acid, tranexamic acid, oil-soluble licorice extract, crunchy extract, toki extract, retinol, retinoic acid, hyaluronic acid, astaxanthin, tocotrienol, ubiquinone, aloe, ogon and other anti-aging agents, glycyrrhetic acid , Glycyrrhizic acid, amino acids, saccharides, mucopolysaccharides, hydrolyzed proteins, sphingolipids, ceramides, phospholipids and other rough skin prevention agents, tocopherol, tocopherol acetate, SOD, β-carotate , Catechin, an anti-oxidant such as polyphenols, .gamma.-oryzanol, minoxidil, assembly extract, capsicum tincture, benzyl nicotinate, pantothenic acid, biotin, and the like hair growth agents such as estradiol.

  EXAMPLES Next, the present invention will be specifically described with reference to examples, but the present invention is not limited to these examples.

Lotion 1
Ethyl alcohol 5.0 mass%
Glycerin 1.0
1,3-butylene glycol 5.0
POP (20) POE (25) Phytosteryl ether
1.0
Sodium hexametaphosphate 0.03
Trimethylglycine 1.0
Sodium polyaspartate 0.1
Vitamin C tetraisopalmitate
0.1
Tocopherol acetate 0.1
EDTA3 sodium 0.1
Carboxyvinyl polymer 0.05
Potassium hydroxide 0.02
Perfume Appropriate amount Phenoxyethanol Appropriate amount Purified water Residue Toner lotion 1 was produced according to the conventional method according to the above formulation. The oily component was stably solubilized, and a transparent lotion was obtained.

Lotion 2
Glycerin 6.0% by mass
Sorbitol 3.0
1,3-butylene glycol 8.0
Hyaluronic acid 0.05
Tocopherol acetate 0.1
Ascorbic acid glucose 0.1
Glyceryl tri-2-ethylhexanoate 0.05
POP (5) POE (30) Phytosteryl ether
2.0
Preservative Appropriate amount Perfume Appropriate amount Purified water Residue Toner lotion 2 was produced according to the above formula according to a conventional method. The oily component was stably solubilized, and a transparent lotion was obtained.

Lotion 3
1,3-butylene glycol 6.0% by mass
Glycerin 5.0
Dipropylene glycol 3.0
Ethanol 10.0
Olive oil 0.2
POP (10) POE (20) phytosteryl ether
3.0
Dipotassium glycyrrhizinate 0.1
Arginine hydrochloride 0.1
Oil-soluble licorice extract 0.05
Tranexamic acid 1.0
Yukinoshita extract 0.1
Ogon Extract 0.1
Citric acid 0.05
Sodium citrate 0.2
EDTA3 sodium 0.05
Preservative Appropriate amount Fragrance Appropriate amount Purified water Residue Toner lotion 3 was produced according to the above-mentioned prescription according to a conventional method. The oily component was stably solubilized, and a transparent lotion was obtained.

(Comparative Example 1)
A lotion was prepared in the same manner as in Example 1 except that the POP (20) POE (25) phytosteryl ether of Example 1 was changed to POE (30) hydrogenated castor oil.

(Comparative Example 2)
A lotion was produced in the same manner as in Example 2 except that POP (5) POE (30) phytosteryl ether in Example 2 was changed to POE (20) octyldodecyl ether.

(Comparative Example 3)
A lotion was produced in the same manner as in Example 3 except that the POP (10) POE (20) phytosteryl ether in Example 3 was changed to POE (20) sorbitan oleate.

Table 1 shows the results of determining and evaluating the usability (stickiness) of the lotions obtained in Examples 1 to 3 and Comparative Examples 1 to 3 based on the actual use of 10 beauty panels.
(Judgment)
◎: Not sticky ○: Slightly sticky, but in a range where there is no problem in use △: Sticky ×: Significantly sticky

  In the present invention, by blending a specific nonionic surfactant and a polyhydric alcohol, a solubilizer that has excellent solubilization ability and good stability and can reduce the stickiness of the polyhydric alcohol is blended. A solubilized cosmetic can be provided.

Claims (2)

In cosmetics containing water-insoluble substances such as fragrances, oils, and oil-soluble drugs,
(A) General formula (1)

[Wherein, R represents a phytosterol residue, m represents an average added mole number of 5 to 30, and n represents an average added mole number of 10 to 50. ] One or more nonionic surfactants comprising a polyoxypropylene and polyoxyethylene adduct of phytosterol represented by the following:
And (B) one or more polyhydric alcohols selected from 1,3-butylene glycol, dipropylene glycol, glycerin and sorbitol. (A) 0.01 to 20.0% by mass of one or more of the nonionic surfactants represented by the general formula (1), and (B) one or more of the polyhydric alcohols. The solubilized cosmetic according to claim 1, which contains 2.0 to 30.0% by mass.