JP5101808B2 - Oil-in-water liquid composition - Google Patents

Description

  The present invention relates to an oil-in-water liquid composition having fine emulsion droplets excellent in stability over time and usability.

In oil-in-water emulsified cosmetics, development of fine emulsification technology for emulsified droplets has been actively conducted in recent years. For example, in Patent Documents 1 to 3, fine emulsified cosmetics with emulsified droplets can be obtained by using an emulsifier having a strong shearing force for an emulsion containing a specific surfactant, an oily component, and an amphiphilic substance. It is disclosed. Further, Patent Document 4 discloses that a gel is formed by presenting an emulsion composed of a specific amphiphile, a surfactant, and oil that can form a gel by applying a strong shearing force to refine the emulsion. A technique is described in which stabilization is achieved by transferring an amphiphilic substance and a surfactant to the interface. Furthermore, Patent Document 5 discloses a translucent lotion made of phospholipid, hydrophilic surfactant, liquid hydrocarbon oil, and ethanol.
JP 2002-12517 A (pages 1 to 6) JP 2001-157835 A (pages 1 to 7) JP 02-78432 A (pages 1 to 8) Japanese Patent Application Laid-Open No. 08-92059 (page 1 to page 11) JP 63-264512 A (pages 1 to 5)

  However, in the prior art that requires the use of an emulsifier having a strong shearing force, it is essential to control the particle size by strictly controlling the shearing force. In the case of a large size, coalescence and creaming of emulsified droplets occur, or the viscosity tends to increase with time, so that stability over time may be inferior. Furthermore, since the viscosity is likely to change with temperature, the stability over time may be poor. Furthermore, when a surfactant as used in Patent Documents 1 to 4 is blended in a considerable amount in cosmetics in order to obtain a desired particle size, the spread during use is heavy and the stickiness is strong. It was necessary to further improve. Moreover, in the technique of patent document 5, the oil agent which can be mix | blended has a restriction | limiting and the effect of the oil agent, such as giving a moist feeling to a back skin, may not be enough. The present invention has been made in view of the above-mentioned problems of the prior art, and its purpose is to provide a fine oil-in-water liquid composition in which oil is stably blended, and when the composition is applied to cosmetics, The object of the present invention is to provide a cosmetic material that has a fresh and pleasing feeling of use and has an excellent skin effect.

  As a result of studying the state of an amphiphilic higher alcohol and various active agents in an aqueous system, the present inventors have conventionally used HLB14-20 polyoxyalkylene sterol ether for fine emulsification. It has been found that unlike an active agent, it does not form a gel. For this reason, the present inventors, as mentioned as the above problem, after forming a gel in the oil-in-water fine emulsification, the problem of the prior art to control the particle size by strictly controlling the shear force In order to solve this problem, an oil-in-water emulsion using a polyoxyalkylene sterol ether of HLB 14 to 20 and a higher alcohol was studied. As a result, oil-in-water liquid compositions with fine emulsion droplets using polyoxyalkylene sterol ethers of HLB 14 to 20 and higher alcohols are excellent in stability over time, and cosmetics containing the liquid compositions are cosmetics. It was found that the skin was sufficiently moisturized and the skin effect was excellent even though it was fresh and easy to use when applied, and the present invention was completed.

That is, the present invention provides the following components (a) to (d):
(A) Polyoxyalkylene sterol ether of HLB 14 to 20 (b) Higher alcohol (c) Oil agent (d) Water is blended, and the average emulsion droplet diameter is 200 nm or less. It is.

  Further, in the present invention, the blending mass ratio of the component (a) and the component (b) is 1: 0.3 to 1: 1, and the sum of the component (a) and the component (b) and the blending of the component (c) An oil-in-water liquid composition having a mass ratio of 1: 0.5 to 1:10. Furthermore, it is an oil-in-water liquid composition characterized in that component (a) is polyoxyalkylene phytosterol ether / polyoxyalkylene phytostanol ether, and further an oil-in-water liquid composition containing phospholipid as component (e) It is a composition. Furthermore, the present invention provides a cosmetic comprising the oil-in-water liquid composition described above.

  The oil-in-water liquid composition of the present invention is not only excellent in stability over time, but also has a good feeling of use and an excellent skin care effect such as moisture retention. For this reason, when an oil-in-water liquid composition is applied to a cosmetic, the skin feels sufficiently moisturized when the cosmetic is applied, and the skin effect is sufficiently moistened. Also excellent.

  Hereinafter, the present invention will be described in further detail. The component (a) HLB14-20 polyoxyalkylene sterol ether used in the present invention is used as an emulsifier in the present invention, and is essential for obtaining a stable finely emulsified liquid composition together with the component (b). It is an ingredient. Furthermore, when blended in cosmetics, a fresh feeling of use with little stickiness is obtained.

  The polyoxyalkylene sterol ether is obtained by adding an alkylene oxide to a sterol. Examples of the structure of the sterol part of the polyoxyalkylene sterol ether include cholesterol, lanosterol, sitosterol, stigmasterol, fucostosterol, spinasterol, campesterol, brassicasterol, and derivatives obtained by hydrogenation or water addition thereof. Can do. Among these sterols, those below sitosterol are mainly obtained from plants, and the mixture is generally called phytosterol. Thus, sterols do not need to be a single structure, and may be a mixture. In addition to the sterol, it may be a lanolin alcohol obtained from wool oil and mainly composed of cholesterol or lanosterol or a hydrogenated product thereof. Further, it may be obtained from animals or plants or bacteria. Among these, from the viewpoint of stability over time, polyoxyalkylene phytosterol ether or polyoxyalkylene phytostanol ether is preferable.

  Examples of the alkylene oxide added to the sterol include ethylene oxide, propylene oxide, butylene oxide, and ethylene / propylene oxide. The added mole number is selected so that the HLB as the surfactant is 14 to 20. Specifically, for example, when the sterol part is mainly composed of cholesterol and phytosterol, the added mole number of ethylene oxide corresponds to about 20 to 50 moles. Of these, adducts of ethylene oxide and propylene oxide are preferable because they have good temporal stability. In the present invention, these active agents are used singly or in combination of two or more. Specifically, such surfactants include, for example, Nikkor BPS-20, Nikkor BPS-25, Nikkor BPS-30 (manufactured by Nikko Chemicals Co., Ltd.), Bell Pole DC-30 (manufactured by Nippon Seika Co., Ltd.), SUNBRIGHT Examples of commercially available products include CS-010, SUNBRIGHT CS-020, and SUNBRIGHT CS-050 (manufactured by Nippon Oil & Fats Co., Ltd.).

  The compounding amount of the polyoxyalkylene sterol ether in the present composition is preferably 0.05 to 10% by mass (hereinafter simply referred to as “%”), more preferably 0.1 to 5%. When blended in this range, the fine oil-in-water emulsion composition has good stability over time, and when used in a cosmetic, it has excellent usability and safety to the skin.

The component (b) higher alcohol used in the present invention is used together with the component (a) for the purpose of strengthening the oil-in-water type emulsion droplet interface and improving the stability.
The higher alcohol of component (b) used in the present invention is a straight-chain saturated alcohol having 6 to 40 carbon atoms, a saturated alcohol having a side chain, a linear unsaturated alcohol, an unsaturated alcohol having a side chain, a hydroxyl group Are multiple alcohols. Specific examples include lauryl alcohol, myristyl alcohol, cetyl alcohol, stearyl alcohol, oleyl alcohol, isostearyl alcohol, behenyl alcohol, batyl alcohol, chimyl alcohol, ceryl alcohol, and myricyl alcohol. These may be used alone or in combination of two or more. Among these, higher alcohols having 16 or more carbon atoms are preferable from the viewpoint of temporal stability.

  As for the preferable compounding quantity of a component (b), it is preferable that the compounding mass ratio with respect to (a) is 0.3-1. If it is this range, the fine oil-in-water-type liquid composition excellent in temporal stability will be obtained.

  The oil agent of component (c) used in the present invention is an essential component for constituting an oil-in-water emulsifier type, and the oil component is used for softening the skin and imparting a moist feeling to the back skin.

  As the oil agent of the component (c) used in the present invention, regardless of the origin of animal oil, vegetable oil, synthetic oil and the like commonly used in cosmetics, and properties such as solid oil, semi-solid oil, liquid oil, volatile oil, Hydrocarbons, fats and oils, waxes, hardened oils, ester oils, fatty acids, silicone oils, fluorinated oils, lanolin derivatives, oily gelling agents, lipophilic surfactants, oil-soluble ultraviolet rays Examples include absorbents. Specifically, hydrocarbons such as liquid paraffin, squalane, petrolatum, polyisobutylene, polybutene, paraffin wax, ceresin wax, microcrystalline wax, montan wax, fish trops wax, olive oil, castor oil, jojoba oil, mink oil , Vegetable oils such as macadamian nut oil, beeswax, carnauba wax, candelilla wax, waxes such as gay wax, owl, cetyl isooctanoate, isopropyl myristate, isopropyl palmitate, octyldodecyl myristate, glyceryl trioctanoate, Polyglyceryl diisostearate, diglyceryl triisostearate, glyceryl tribehenate, pentaerythritol ester of rosin acid, neopentyl glycol dioctanoate, Esters of terol fatty acid esters, N-lauroyl-L-glutamic acid di (cholesteryl, behenyl, octyldodecyl), fatty acids such as stearic acid, lauric acid, myristic acid, behenic acid, isostearic acid, oleic acid, rosin acid, Silicones such as low polymerization dimethylpolysiloxane, high polymerization dimethylpolysiloxane, methylphenylpolysiloxane, decamethylcyclopentasiloxane, octamethylcyclotetrasiloxane, polyether-modified polysiloxane, cross-linked organopolysiloxane, fluorine-modified silicone Fluorine oils such as perfluoropolyether, perfluorodecane, perfluorooctane, lanolin derivatives such as lanolin, lanolin acetate, lanolin fatty acid isopropyl, lanolin alcohol, Oily gelling agents such as string fatty acid ester, sucrose fatty acid ester, starch fatty acid ester, 12-hydroxystearic acid, aluminum stearate, calcium stearate, lipophilicity such as glyceryl monostearate, sorbitan tristearate, sorbitan sesquioleate Surfactants, ethyl paraaminobenzoate, paramethoxycinnamate-2-ethylhexyl, oil-soluble UV absorbers such as 4-tert-butyl-4'-methoxydibenzoylmethane, oxybenzone, and the like Can be used singly or in combination of two or more.

  More preferably, the blending mass ratio of the sum of component (a) and component (b) and component (c) is from 1: 0.5 to 1:10. Within this range, the oil-in-water liquid composition is excellent in stability over time, and when used on the skin, the skin effect is sufficient.

  The component (d) water used in the present invention is an essential component for constituting an oil-in-water emulsifier type, and imparts a fresh feel during and after use. The blending amount of the component (d) water is not particularly limited, and can be appropriately blended according to the amount of other components.

  In the present invention, when a phospholipid is further blended, the stability over time is further improved.

  Examples of the phospholipid of component (e) used in the present invention include lecithin, phosphatidylethanolamine, phosphatidic acid, phosphatidylinositol, phosphatidylserine, phosphatidylcholine, phosphatidylglycerol, sphingo Examples include myelin and cardiolipin. Further, those hydrogenated according to a conventional method can be mentioned. In particular, hydrogenated natural lecithin obtained by hydrogenating soybean lecithin, egg yolk lecithin, corn lecithin, cottonseed oil lecithin, rapeseed lecithin or the like is preferably used.

  Moreover, it is more preferable from a viewpoint of temporal stability that the compounding mass ratio of a component (a) and a component (e) is 1: 0.2-1: 1.5.

  The particle size of the oil-in-water liquid composition of the present invention is 200 nm or less. Within this range, creaming is unlikely to occur and the stability over time is good.

  In the present invention, the emulsion droplet size was measured by diluting the prepared oil-in-water liquid composition with water using a Beckman Coulter N5 Particle Analyzer by a dynamic light scattering method, and measuring the average particle size.

  The “liquid” in the fine oil-in-water composition of the present invention refers to a liquid whose viscosity at 30 ° C. is 1 to 2000 mPa · s as measured with a Brookfield rotary viscometer.

  The oil-in-water emulsified liquid composition of the present invention is prepared by a generally known technique such as dispersion emulsification, phase inversion emulsification, gel emulsification, liquid crystal emulsification, D phase emulsification, PIT emulsification using a homomixer, a disper mixer, or the like. Is possible. In addition, the emulsifier that can apply a shear force stronger than the homomixer to the mixed dispersion having the essential components, such as a manton gourin, a French press, a colloid mill, a microfluidizer, and an ultrasonic emulsifier It can also be prepared by treating with.

  In order to examine how the present invention is different from the surfactants used in conventional fine emulsification, the structure of (a) polyoxyalkylene sterol ether and (b) higher alcohol in water system We examined whether it was made. In the method, at 80 ° C., various surfactants, higher alcohol cetanol and water were heated and mixed, and allowed to cool to room temperature (25 ° C.). The test results are shown in Table 1. As shown in Table 1, it can be seen that unlike other surfactants having the same level of HLB, a combination of polyoxyalkylene sterol ether and higher alcohol does not form a gel (α-gel). Usually, amphiphiles such as higher alcohols and surfactants form a state called α-gel in the aqueous phase, which is used to increase the interfacial area by finely emulsifying droplets using a high-pressure shear emulsifier, etc. Conventionally, stabilization of a fine emulsion has been achieved by orienting an amphiphile and a surfactant at the oil-water interface. However, the combination of polyoxyalkylene sterol ether and higher alcohol does not originally form a gel in water, so it is more orientated more efficiently at the interface, and it is stable in liquid form without strictly controlling the interfacial area of the emulsion droplets. It is thought that a fine emulsion was formed.

  In addition to the above essential components, the fine oil-in-water liquid composition of the present invention comprises a water-soluble polymer, a monohydric or polyhydric alcohol, an aqueous component, a surfactant, a powder, an ultraviolet absorber, a humectant, Antioxidants, preservatives, fragrances and the like can be blended within a range that does not impair the effects of the present invention.

  The fine oil-in-water liquid composition of the present invention has a moist feeling when applied and has a sufficient moist feeling on the back skin and is excellent in skin effect. It is more preferable to mix the mold liquid composition in the cosmetic because the effects of the present invention are remarkably exhibited.

  When the oil-in-water liquid composition of the present invention is blended in cosmetics, the blending amount is preferably 5% to 90%. Within this range, when the cosmetic is applied, the skin feels fresh and easy to use, a sufficiently moist feeling is obtained on the back skin, and the skin effect is excellent.

  When blending an oil-in-water liquid composition in cosmetics, a fine oil-in-water liquid composition is added with a water-soluble polymer and the like within a range that does not impair its properties, It can be dispersed in an aqueous system containing a humectant or the like. In addition to the essential components described above, components used in normal cosmetics, such as water-soluble polymers, alcohols, aqueous components, surfactants, powders, ultraviolet absorbers, humectants, antioxidants, Beauty agents, antiseptics, fragrances, refreshing agents, and the like for the purpose of whitening and antioxidant can be blended within a range not impairing the effects of the present invention.

  Examples of whitening agents include arbutin, vitamin C and its derivatives, hawthorn extract, Inchinkou (Kawara mugwort) extract, licorice extract, Clara extract, wheat extract, saicin extract, rice and rice bran extract, black Examples include currant extract, Ibukitorano extract, Neubara (Agetsu) extract, Ezocogi extract, Sakuhakuhi extract, Toki extract, coffee extract, pearl barley (Yokuinin) extract and the like.

Antioxidants include coenzyme Q10, alpha lipoic acid, vitamin E and derivatives thereof, carotenoids, dibutylhydroxytoluene, butylhydroxyanisole, rutin and derivatives thereof, glutathione and derivatives thereof, superoxide dismutase, mannitol, caquette extract, geno shoco Extract, Peonies extract, Superoxide Dismutase, Ginkgo biloba extract, Scarab (Ogon) extract, Mikaika (Maikai, Hermanus) extract, Tormentilla extract, Grape extract, Yashajitsu (Yasha) extract, Yukinoshita extract, Examples include rosemary (mannenro) extract, tea extract (Oolong tea, black tea, green tea, etc.) and the like.

  As a use, it can be used as makeup cosmetics such as basic cosmetics for face, limbs and body such as lotion, milky lotion, cream, cosmetic liquid and pack, foundation, mascara, eye color, eyeliner, eye shadow and the like. In particular, basic cosmetics for lotions, milky lotions, creams, cosmetics, packs and the like, face, limbs, body and the like are preferable because the effects of the present invention are more remarkably exhibited.

  The present invention is useful in the point that the stability over time is not impaired even if an electrolyte that has been difficult to be stably blended in a fine emulsion is conventionally blended in cosmetics. In particular, the present invention in which an electrolyte, which is a cosmetic ingredient effective for the skin in terms of dermatology, can be blended is particularly useful in skin care cosmetics. Specifically, for example, glycine, alanine, valine, leucine, isoleucine, phenylalanine, tyrosine, threonine, serine, proline, hydroxyproline, tryptophan, thyroxine, methionine, cystine, cysteine, aspartic acid, glutamic acid, asparagine, glutamine, lysine , Amino acids such as arginine and histidine and water-soluble derivatives of amino acids such as trimethylglycine and N-acetyl-glutamic acid, hydroxyacetic acid, lactic acid, β-hydroxypropionic acid, α-hydroxybutyric acid, α-hydroxyisobutyric acid, α-hydroxy Isocaproic acid, oxalic acid, malonic acid, succinic acid, glutaric acid, adipic acid, pimelic acid, suberic acid, azelaic acid, fumaric acid, maleic acid, malic acid, tartronic acid, citric acid, tartaric acid Sodium salt such as pyrrolidone carboxylic acid, potassium salt, triethanolamine salt, ammonium salt, dipotassium glycyrrhizinate, urea, L-ascorbic acid-2-sodium phosphate, L-ascorbic acid-2-magnesium phosphate, ascorbic acid glucoside , Phenylbenzimidazole sulfonate, and hydroxymethoxybenzophenone sulfonate. The blending amount of the electrolyte is more preferably 0.1% to 5% in the cosmetic from the viewpoint of cosmetic effect and stability over time.

  EXAMPLES Next, although an Example is given and this invention is demonstrated still in detail, this invention is not limited at all by these.

Examples 1 to 6 and Comparative Examples 1 to 3: Oil-in-water liquid compositions The cosmetic liquids shown in Table 1 and Table 2 below were prepared by the following production method, (1) stability over time, (2) emulsion droplet size The evaluation items were evaluated and determined by the following methods, and the results are shown in Table 2 and Table 3. Examples 4 to 6 and 11 are reference examples.

(Production method)
A: Components 1 to 7 are dissolved and mixed at 75 ° C.
B: Component 8 was heated to 70 ° C and added to A, and then component 9 heated to 70 ° C was added and emulsified.
C: This was cooled and degassed and then treated with a microfluidizer to obtain an oil-in-water liquid composition.

[Evaluation item 1: Evaluation method and determination method of stability over time]
The change in appearance of a sample that was allowed to stand for 6 months in a constant temperature bath at 40 ° C. was determined according to the following (Reference A).

(Standard A)
No separation or creaming is observed after 6 months:
No separation at 6 months, but some creaming:
Separation and creaming are observed in one month: △
Separation and creaming are recognized in one week: ×

[Evaluation item 2: Measuring method of emulsion droplet size]
The particle diameters of the emulsified droplets of the oil-in-water liquid compositions shown in Tables 2 and 3 were measured with COULTER N5 type (manufactured by BECKMAN COULTER).

As is clear from the results of Tables 2 and 3, the oil-in-water liquid compositions of Examples 1 to 6 of the present invention are more stable over time than the oil-in-water liquid compositions of Comparative Examples 1 to 3. It was excellent in properties.
On the other hand, Comparative Example 1 in which the component (b) is not blended, Comparative Example 2 in which the HLB of the component (a) is low, and Comparative Example 3 in which the sterol part of the component (a) is stearyl alcohol have an average particle size of more than 200 nm. Also, the stability over time was inferior.

Examples 7 to 11 and Comparative Examples 4 to 5: Oil-in-water essences The oil-in-water essences shown in Table 4 below were prepared by the following production method, and (1) stability over time, (2) fresh elongation, 3) Moist feeling of the back skin, (4) Emulsion droplet size, stability over time, and emulsion droplet size are the same as in the above examples of the oil-in-water liquid emulsion composition, and other evaluation items are as follows. The results are shown in Table 4 together with the results. Examples 9 and 10 are reference examples.

(Production method)
A: Components 1 to 5 are dissolved and mixed at 75 ° C.
B: Components 6 and 7 were heated to 75 ° C and added to A, and then component 8 heated to 75 ° C was added and emulsified.
C: After cooling and defoaming, an oil-in-water liquid composition was prepared by treating with a microfluidizer, and components 9 to 13 were added and mixed to obtain an oil-in-water cosmetic liquid.

[Evaluation item (2) Fresh stretch, (3) Evaluation method and determination method of moist feeling of the back skin]
20 professional evaluation panels evaluated the feeling of use (freshness and moistness of the back skin) when applied to the skin according to the following (Standard B) 5-step evaluation criteria, and the average score (Standard C) According to the determination.

(Standard B) Five-level evaluation standard (Evaluation) (Evaluation)
5 points: Very good 4 points: Good 3 points: Normal 2 points: Bad 1 point: Very bad (Standard C)
(Judgment) (Grade)
◎: Average point 4.5 points or more ○: Average point 3.5 points or more and less than 4.5 points △: Average point 2.5 points or more and less than 3.5 points ×: Average point less than 2.5 points

  As is apparent from the results in Table 4, the cosmetic liquids of Examples 7 to 11 of the present invention have an average particle size of 200 nm or less, and are stable over time and feeling of use (freshness and moist feeling on the back skin). It was excellent. On the other hand, the comparative example 4 which does not mix | blend a component (a) and the comparative example 5 which does not mix | blend a component (b) had an average particle diameter exceeding 200 nm, and were inferior also to temporal stability and usability | use_condition.

Example 12: Lotion (Ingredient) (%)
1. Polyoxyethylene (20) phytosterol (HLB15.5) 0.3
2. Behenyl alcohol 0.2
3. Polyoxyethylene (60) hydrogenated castor oil 0.2
4). Hydrogenated soybean phospholipid 0.3
5.1,3-Butylene glycol 8.0
6). Glycerin 8.0
7). Tetra-2-ethylhexanoic acid pentaerythritol 1.0
8). Purified water 30.0
9. Alcohol 5.0
10. Theanine 1.0
11. Acetylglutamic acid 0.1
12 Sodium hydroxide
13. Purified water remaining
14 Perfume 0.02
15. Soybean extract 0.5

(Production method)
A: Components 1 to 6 are dissolved and mixed at 80 ° C.
B: Component 7 was heated to 80 ° C. and added to A, and then component 8 heated to 75 ° C. was added and emulsified.
C: This was cooled and defoamed, then treated with a microfluidizer to prepare an oil-in-water liquid composition, and components 9 to 15 were added and mixed to obtain a skin lotion.

The obtained lotion of Example 12 was excellent in stability over time and feeling in use (freshness and moist feeling in the back skin). The average emulsified droplet diameter of the lotion was 90 nm.

Example 13: Nonwoven fabric impregnated type pack material (component) (%)
1. Polyoxyethylene (25) Phytostanol (HLB14.5) 1.0
2. Stearyl alcohol 0.2
3. Cetanol 0.2
4). Hydrogenated soybean phospholipid 0.3
5. Propylene glycol 10.0
6). Diglycerin 8.0
7). Liquid paraffin 1.0
8). Meadow foam oil 0.5
9. Microcrystalline wax 5.0
10. Purified water 1.0
11. Ethanol 3.0
12 Purified water remaining
13. Ascorbic acid glucoside 2.0
14 Sodium hydroxide appropriate amount15. Fragrance 0.01

(Production method)
A: Components 1 to 6 are dissolved and mixed at 80 ° C.
B: Components 7 to 9 were heated to 80 ° C and added to A, and then component 10 heated to 75 ° C was added and emulsified.
C: This was cooled and degassed to prepare an oil-in-water liquid composition, and the undiluted nonwoven solution was impregnated with the stock solution mixed with components 11 to 15 to obtain a nonwoven fabric-impregnated type pack.

The obtained nonwoven fabric-impregnated type pack material of Example 13 was excellent in stability over time and feeling in use (fresh feeling in use, moist feeling in the back skin). The average emulsified droplet diameter of the stock solution impregnated in the nonwoven fabric impregnated type pack was 190 nm.

Example 14: Cosmetic liquid (ingredient) (%)
1. Polyoxyethylene (20) phytosterol (HLB15.5) 0.3
2. Behenyl alcohol 0.2
3. Hydrogenated soybean phospholipid 0.3
4.1,3-Butylene glycol 8.0
5. Glycerin 8.0
6). Squalane 1.0
7). Dipentaglycol neopentyl glycol 0.5
8). Purified water 30.0
9. Alcohol 5.0
10. Alpha lipoic acid 0.2
11. Clara extract 1.0
12 Citric acid 0.1
13. Sodium citrate 0.2
14 Edetate disodium 0.1
15. SIMULGEL EG (Note 1) 1.0
16. Purified water remaining
(Note 1) Sodium acrylate / acryloyldimethyltaurate sodium copolymer (SEPPIC)

(Production method)
A: Components 1 to 5 are dissolved and mixed at 80 ° C.
B: Components 6 to 7 were heated to 80 ° C and added to A, and then component 8 heated to 75 ° C was added and emulsified.
C: This was cooled and defoamed, then treated with a microfluidizer to prepare an oil-in-water liquid composition, and components 9 to 16 were added and mixed to obtain a cosmetic liquid.

The obtained beauty serum of Example 14 was excellent in stability over time and feeling in use (freshness and moist feeling in the back skin). The average emulsified droplet diameter of the lotion was 110 nm.

Example 15: serum (component) (%)
1. Polyoxyethylene (20) phytosterol (HLB15.5) 0.3
2. Behenyl alcohol 0.2
3. Hydrogenated soybean phospholipid 0.3
4.1,3-Butylene glycol 8.0
5. Glycerin 8.0
6). Liquid paraffin 0.7
7). Dipentaglycol neopentyl glycol 0.5
8). Coenzyme Q10 0.01
9. Purified water 30.0
10. Alcohol 5.0
11. Arbutin 3.0
12 Citric acid 0.1
13. Sodium citrate 0.2
14 Edetate disodium 0.1
15. Sodium carboxymethylcellulose 0.3
16. Purified water remaining

(Production method)
A: Components 1 to 5 are dissolved and mixed at 80 ° C.
B: Components 6 to 8 were heated to 80 ° C. and added to A, and then component 9 heated to 75 ° C. was added and emulsified.
C: This was cooled and defoamed, then treated with a microfluidizer to prepare an oil-in-water liquid composition, and components 10 to 16 were added and mixed to obtain a cosmetic liquid.

The obtained beauty serum of Example 15 was excellent in stability over time and feeling in use (freshness and moist feeling in the back skin). The average emulsified droplet diameter of the lotion was 110 nm.

Claims (5)

The following components (a) to (d)
(A) polyoxyalkylene sterol ether 0.1 HLB14~20 ~ 5 wt% and (b) higher alcohol component (c) (b) other than the oil (d) water (e) a phospholipid component (a) component The blending mass ratio of (b) is 1: 0.3 to 1: 1, and the blending mass ratio of the sum of component (a) and component (b) and component (c) is 1: 0.5 to 1: were blended at 10, the average emulsion droplet size of Ri der less 200 nm, and oil-in-water liquid composition viscosity of 30 ° C. is characterized 1~2000mPa · s der Rukoto. The oil-in-water liquid composition according to claim 1, wherein component (a) is polyoxyalkylene phytosterol ether and / or polyoxyalkylene phytostanol ether. The oil-in-water liquid composition according to claim 1 or 2, wherein the component (b) is a higher alcohol having 16 or more carbon atoms. The oil-in-water liquid composition according to any one of claims 1 to 3, wherein the blending mass ratio of the component (a) and the component (e) is 1: 0.2 to 1: 1.5. A cosmetic comprising the oil-in-water liquid composition according to any one of claims 1 to 4.