JP4949473B2 - 肝機能を評価するためのバイオマーカー - Google Patents

肝機能を評価するためのバイオマーカー Download PDF

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Publication number
JP4949473B2
JP4949473B2 JP2009527200A JP2009527200A JP4949473B2 JP 4949473 B2 JP4949473 B2 JP 4949473B2 JP 2009527200 A JP2009527200 A JP 2009527200A JP 2009527200 A JP2009527200 A JP 2009527200A JP 4949473 B2 JP4949473 B2 JP 4949473B2
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Japan
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liver
individual
patients
adma
liver disease
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JP2009527200A
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Japanese (ja)
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JP2010502979A (ja
JP2010502979A5 (https=
Inventor
ジャラン,ラジーヴ
ピー ムケルジー,ラジェシュワル
デーヴィス,ネイサン
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UCL Business Ltd
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UCL Biomedica PLC
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/76Assays involving albumins other than in routine use for blocking surfaces or for anchoring haptens during immunisation
    • G01N2333/765Serum albumin, e.g. HSA
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/08Hepato-biliairy disorders other than hepatitis
    • G01N2800/085Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2009527200A 2006-09-07 2007-09-07 肝機能を評価するためのバイオマーカー Active JP4949473B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0617581.4A GB0617581D0 (en) 2006-09-07 2006-09-07 Biomarkers for assessing liver function
GB0617581.4 2006-09-07
PCT/GB2007/003362 WO2008029145A1 (en) 2006-09-07 2007-09-07 Biqmarkers for assessing liver function

Publications (3)

Publication Number Publication Date
JP2010502979A JP2010502979A (ja) 2010-01-28
JP2010502979A5 JP2010502979A5 (https=) 2010-10-21
JP4949473B2 true JP4949473B2 (ja) 2012-06-06

Family

ID=37232490

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009527200A Active JP4949473B2 (ja) 2006-09-07 2007-09-07 肝機能を評価するためのバイオマーカー

Country Status (16)

Country Link
US (1) US8455220B2 (https=)
EP (1) EP2059817B1 (https=)
JP (1) JP4949473B2 (https=)
KR (1) KR20090083335A (https=)
AT (1) ATE488772T1 (https=)
AU (1) AU2007293302A1 (https=)
CA (1) CA2662597A1 (https=)
DE (1) DE602007010644D1 (https=)
EA (1) EA200970256A1 (https=)
ES (1) ES2353835T3 (https=)
GB (1) GB0617581D0 (https=)
IL (1) IL197271A0 (https=)
MX (1) MX2009002378A (https=)
NO (1) NO20090993L (https=)
WO (1) WO2008029145A1 (https=)
ZA (1) ZA200901432B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2823349T3 (es) 2011-05-31 2021-05-06 Univ Colorado Regents Procedimiento para evaluación de la función hepática y el flujo sanguíneo portal
CA2891281C (en) 2012-11-12 2023-11-28 The Regents Of The University Of Colorado, A Body Corporate Disease severity index for assessment of chronic liver disease and method for diagnosis of three distinct subtypes of primary sclerosing cholangitis
WO2014190170A1 (en) * 2013-05-22 2014-11-27 The Regents Of The University Of California Biomarker composite test for hepatic vein pressure gradient and cirrhosis treatment
US10335452B2 (en) * 2014-10-24 2019-07-02 Mallinckrodt Hospital Products IP Limited Method of treating patients with hepatorenal syndrome type 1
CN105181692A (zh) * 2015-09-30 2015-12-23 山东博科生物产业有限公司 一种缺血修饰白蛋白比色法检测试剂盒
ES2761266T3 (es) * 2015-11-10 2020-05-19 Inst Nat Sante Rech Med Métodos para predicción del tiempo de supervivencia de los pacientes con cirrosis alcohólica descompensada
US20220018852A1 (en) * 2018-11-20 2022-01-20 Inserm (Institute National De Ka Santé Et De La Recherche Médicale) Methods and kits for detecting liver dysfunction in a subject
CN121331222B (zh) * 2025-12-15 2026-03-10 北京大学 基于蛋白质组的慢性肝脏疾病发病预测的蛋白组合、预测模型及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997034605A1 (en) * 1996-03-21 1997-09-25 Mayo Foundation For Medical Education And Research Use of nicotine to treat liver disease
CA2415174A1 (en) * 2000-07-06 2002-01-17 Thomas W. Bell Methods and kits for the detection of arginine compounds
WO2003046538A1 (en) * 2001-11-26 2003-06-05 Ischemia Technologies, Inc. Electrochemical detection of ischemia
AU2003261424A1 (en) * 2002-08-06 2004-02-23 Nitromed, Inc. Nitrosated and/or nitrosylated ursodeoxycholic acid compounds, compositions and methods of use
AU2003290784A1 (en) 2002-11-15 2004-06-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for detecting asymmetric dimethylarginine in a biological sample
WO2005039598A1 (en) 2003-10-24 2005-05-06 Intermune, Inc. Method of treating alcoholic liver disease
DE10351238A1 (de) * 2003-11-03 2005-06-02 Roche Diagnostics Gmbh Diagnosestellung von akuten myokardialen, ischämischen Erkrankungen durch Kombination von Markern

Also Published As

Publication number Publication date
WO2008029145A1 (en) 2008-03-13
EP2059817B1 (en) 2010-11-17
JP2010502979A (ja) 2010-01-28
GB0617581D0 (en) 2006-10-18
ZA200901432B (en) 2010-06-30
US8455220B2 (en) 2013-06-04
AU2007293302A1 (en) 2008-03-13
DE602007010644D1 (de) 2010-12-30
EP2059817A1 (en) 2009-05-20
US20090280519A1 (en) 2009-11-12
EA200970256A1 (ru) 2009-08-28
CA2662597A1 (en) 2008-03-13
KR20090083335A (ko) 2009-08-03
NO20090993L (no) 2009-04-03
ES2353835T3 (es) 2011-03-07
IL197271A0 (en) 2009-12-24
MX2009002378A (es) 2009-03-20
ATE488772T1 (de) 2010-12-15

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