JP4932152B2 - 脈管の傷害後の再狭窄を防止するための単独またはシロリムスとの組み合わせにおけるトリコスタチンの局所的な脈管配給 - Google Patents

脈管の傷害後の再狭窄を防止するための単独またはシロリムスとの組み合わせにおけるトリコスタチンの局所的な脈管配給 Download PDF

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Publication number
JP4932152B2
JP4932152B2 JP2004366355A JP2004366355A JP4932152B2 JP 4932152 B2 JP4932152 B2 JP 4932152B2 JP 2004366355 A JP2004366355 A JP 2004366355A JP 2004366355 A JP2004366355 A JP 2004366355A JP 4932152 B2 JP4932152 B2 JP 4932152B2
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Prior art keywords
stent
various
certain
rapamycin
coating
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Expired - Fee Related
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JP2004366355A
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JP2005199058A (ja
JP2005199058A5 (enExample
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ロバート・ファロティコ
トム・ジェイ・パリー
ジョナサン・ゾン・ザオ
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Cordis Corp
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Cordis Corp
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432—Inhibitors, antagonists
    • A61L2300/434—Inhibitors, antagonists of enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
JP2004366355A 2003-12-19 2004-12-17 脈管の傷害後の再狭窄を防止するための単独またはシロリムスとの組み合わせにおけるトリコスタチンの局所的な脈管配給 Expired - Fee Related JP4932152B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US742346 2003-12-19
US10/742,346 US8652502B2 (en) 2003-12-19 2003-12-19 Local vascular delivery of trichostatin A alone or in combination with sirolimus to prevent restenosis following vascular injury

Publications (3)

Publication Number Publication Date
JP2005199058A JP2005199058A (ja) 2005-07-28
JP2005199058A5 JP2005199058A5 (enExample) 2011-08-25
JP4932152B2 true JP4932152B2 (ja) 2012-05-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004366355A Expired - Fee Related JP4932152B2 (ja) 2003-12-19 2004-12-17 脈管の傷害後の再狭窄を防止するための単独またはシロリムスとの組み合わせにおけるトリコスタチンの局所的な脈管配給

Country Status (5)

Country Link
US (1) US8652502B2 (enExample)
EP (1) EP1550472A1 (enExample)
JP (1) JP4932152B2 (enExample)
CN (1) CN1669537B (enExample)
CA (1) CA2490170C (enExample)

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CN1669537A (zh) 2005-09-21
JP2005199058A (ja) 2005-07-28
EP1550472A1 (en) 2005-07-06
US20050136090A1 (en) 2005-06-23
US8652502B2 (en) 2014-02-18
CN1669537B (zh) 2011-10-05
CA2490170A1 (en) 2005-06-19

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