JP4916889B2 - 血管新生を調節するための方法および組成物 - Google Patents

血管新生を調節するための方法および組成物 Download PDF

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JP4916889B2
JP4916889B2 JP2006552252A JP2006552252A JP4916889B2 JP 4916889 B2 JP4916889 B2 JP 4916889B2 JP 2006552252 A JP2006552252 A JP 2006552252A JP 2006552252 A JP2006552252 A JP 2006552252A JP 4916889 B2 JP4916889 B2 JP 4916889B2
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ccx
ckr2
cells
mmol
methyl
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JP2007520564A (ja
JP2007520564A5 (enExample
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ジェニファー バーンズ
ブレットン サマーズ
ユー ワン
モーリーン ハワード
トーマス シャル
チェンホア ミャオ
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ケモセントリックス インコーポレーティッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/195Chemokines, e.g. RANTES
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2006552252A 2004-02-03 2005-02-02 血管新生を調節するための方法および組成物 Expired - Fee Related JP4916889B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US54184904P 2004-02-03 2004-02-03
US60/541,849 2004-02-03
US59895804P 2004-08-04 2004-08-04
US60/598,958 2004-08-04
US62619504P 2004-11-08 2004-11-08
US60/626,195 2004-11-08
PCT/US2005/003521 WO2005074645A2 (en) 2004-02-03 2005-02-02 Methods and compositions for modulating angiogenesis

Publications (3)

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JP2007520564A JP2007520564A (ja) 2007-07-26
JP2007520564A5 JP2007520564A5 (enExample) 2008-03-27
JP4916889B2 true JP4916889B2 (ja) 2012-04-18

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JP2006552252A Expired - Fee Related JP4916889B2 (ja) 2004-02-03 2005-02-02 血管新生を調節するための方法および組成物

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Country Link
US (1) US20050214287A1 (enExample)
EP (1) EP1715892A4 (enExample)
JP (1) JP4916889B2 (enExample)
AU (1) AU2005209921B2 (enExample)
CA (1) CA2554880A1 (enExample)
IL (1) IL177104A (enExample)
WO (1) WO2005074645A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7417062B2 (en) 2004-09-29 2008-08-26 Chemocentryx, Inc. Substituted arylamides
EP1909575A2 (en) * 2005-06-29 2008-04-16 ChemoCentryx Inc Substituted n-cinnamyl benzamides
US8088895B2 (en) * 2006-10-18 2012-01-03 Chemocentryx, Inc. Antibodies that bind CXCR7 epitopes
JP2009091339A (ja) * 2007-10-12 2009-04-30 Seikagaku Kogyo Co Ltd 関節リウマチの処置剤
DK2349273T3 (en) * 2008-11-04 2015-07-13 Chemocentryx Inc Modulators of CXCR7
US20110014121A1 (en) * 2008-11-04 2011-01-20 Chemocentryx, Inc. Modulators of cxcr7
US8853202B2 (en) * 2008-11-04 2014-10-07 Chemocentryx, Inc. Modulators of CXCR7
WO2010107832A1 (en) 2009-03-17 2010-09-23 Bracco Imaging Spa Lhrh-ii peptide analogs
KR102196374B1 (ko) 2012-11-29 2020-12-31 케모센트릭스, 인크. Cxcr7 길항제
BR112021011222A2 (pt) 2018-12-12 2021-08-24 Chemocentryx, Inc. Inibidores de cxcr7 para o tratamento de câncer
CN111593022B (zh) * 2018-12-27 2023-10-24 广州溯原生物科技股份有限公司 vMIP-Ⅱ诱导CD8+ T细胞去磷酸化为Tcm及其在药物中的应用
EP4326257A4 (en) 2021-04-19 2025-03-12 ChemoCentryx, Inc. AZETIDINYLACETAMIDES AS CXCR7 INHIBITORS

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006515854A (ja) * 2002-12-20 2006-06-08 ケモセントリックス, インコーポレイテッド ヒト腫瘍発現ccxckr2の阻害剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020166133A1 (en) * 1998-02-10 2002-11-07 Millennium Pharmaceuticals, Inc Neokine protein and nucleic acid molecules and uses therefor
EP1061944B1 (en) * 1998-03-13 2004-01-28 The University Of British Columbia Therapeutic chemokine receptor antagonists
US20020107196A1 (en) * 1998-07-21 2002-08-08 Smithkline Beecham Corporation Method for inducing chemotaxis in endothelial cells by administering stromal cell derived factor-1alpha
WO2002022599A2 (en) * 2000-09-15 2002-03-21 Anormed Inc. Chemokine receptor binding heterocyclic compounds
JPWO2002094261A1 (ja) * 2001-05-24 2004-09-02 呉羽化学工業株式会社 含窒素化合物からなるcxcr4拮抗作用を有する薬剤
US7253007B2 (en) * 2001-11-30 2007-08-07 Chemocentryx, Inc. Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
US20060275769A1 (en) * 2003-01-06 2006-12-07 Oregon Health & Science University Methods of treatment and diagnosis of kaposi's sarcoma (ks) and ks related diseases

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006515854A (ja) * 2002-12-20 2006-06-08 ケモセントリックス, インコーポレイテッド ヒト腫瘍発現ccxckr2の阻害剤

Also Published As

Publication number Publication date
JP2007520564A (ja) 2007-07-26
EP1715892A2 (en) 2006-11-02
WO2005074645A2 (en) 2005-08-18
IL177104A0 (en) 2006-12-10
AU2005209921B2 (en) 2011-04-07
AU2005209921A1 (en) 2005-08-18
WO2005074645A3 (en) 2005-12-22
IL177104A (en) 2010-12-30
EP1715892A4 (en) 2008-07-09
CA2554880A1 (en) 2005-08-18
US20050214287A1 (en) 2005-09-29

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