JP4916889B2 - 血管新生を調節するための方法および組成物 - Google Patents
血管新生を調節するための方法および組成物 Download PDFInfo
- Publication number
- JP4916889B2 JP4916889B2 JP2006552252A JP2006552252A JP4916889B2 JP 4916889 B2 JP4916889 B2 JP 4916889B2 JP 2006552252 A JP2006552252 A JP 2006552252A JP 2006552252 A JP2006552252 A JP 2006552252A JP 4916889 B2 JP4916889 B2 JP 4916889B2
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- ccx
- ckr2
- cells
- mmol
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- GITQNHWJGBLHOJ-UHFFFAOYSA-N CCCC(CCN(Cc1cc(cccc2)c2[o]1)C(c(cc1OC)cc(OC)c1OC)=O)N(C)C Chemical compound CCCC(CCN(Cc1cc(cccc2)c2[o]1)C(c(cc1OC)cc(OC)c1OC)=O)N(C)C GITQNHWJGBLHOJ-UHFFFAOYSA-N 0.000 description 1
- MCPDAPUXUPKDSL-UHFFFAOYSA-N CCCCC(CCN)NC Chemical compound CCCCC(CCN)NC MCPDAPUXUPKDSL-UHFFFAOYSA-N 0.000 description 1
- ARGJOAXJMKMKTM-UHFFFAOYSA-N CN1C(CCNCc2cc3ccccc3[o]2)CCC1 Chemical compound CN1C(CCNCc2cc3ccccc3[o]2)CCC1 ARGJOAXJMKMKTM-UHFFFAOYSA-N 0.000 description 1
- ADDZHRRCUWNSCS-UHFFFAOYSA-N O=Cc1cc2ccccc2[o]1 Chemical compound O=Cc1cc2ccccc2[o]1 ADDZHRRCUWNSCS-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/195—Chemokines, e.g. RANTES
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54184904P | 2004-02-03 | 2004-02-03 | |
| US60/541,849 | 2004-02-03 | ||
| US59895804P | 2004-08-04 | 2004-08-04 | |
| US60/598,958 | 2004-08-04 | ||
| US62619504P | 2004-11-08 | 2004-11-08 | |
| US60/626,195 | 2004-11-08 | ||
| PCT/US2005/003521 WO2005074645A2 (en) | 2004-02-03 | 2005-02-02 | Methods and compositions for modulating angiogenesis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007520564A JP2007520564A (ja) | 2007-07-26 |
| JP2007520564A5 JP2007520564A5 (cg-RX-API-DMAC7.html) | 2008-03-27 |
| JP4916889B2 true JP4916889B2 (ja) | 2012-04-18 |
Family
ID=34841735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006552252A Expired - Fee Related JP4916889B2 (ja) | 2004-02-03 | 2005-02-02 | 血管新生を調節するための方法および組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20050214287A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1715892A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4916889B2 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2005209921B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2554880A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL177104A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2005074645A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006038989A1 (en) * | 2004-09-29 | 2006-04-13 | Chemocentryx, Inc. | Substituted arylamides |
| AU2006263657A1 (en) * | 2005-06-29 | 2007-01-04 | Chemocentryx, Inc. | Substituted N-cinnamyl benzamides |
| US8088895B2 (en) * | 2006-10-18 | 2012-01-03 | Chemocentryx, Inc. | Antibodies that bind CXCR7 epitopes |
| JP2009091339A (ja) * | 2007-10-12 | 2009-04-30 | Seikagaku Kogyo Co Ltd | 関節リウマチの処置剤 |
| US8853202B2 (en) * | 2008-11-04 | 2014-10-07 | Chemocentryx, Inc. | Modulators of CXCR7 |
| US20110014121A1 (en) * | 2008-11-04 | 2011-01-20 | Chemocentryx, Inc. | Modulators of cxcr7 |
| CA2742515C (en) * | 2008-11-04 | 2017-07-11 | Chemocentryx, Inc. | 1,4-diazepane modulators of cxcr7 |
| US20120045393A1 (en) | 2009-03-17 | 2012-02-23 | Linder Karen E | Lhrh-ii peptide analogs |
| MX359651B (es) | 2012-11-29 | 2018-10-05 | Chemocentryx Inc | Antagonistas de cxcr7. |
| MX2021006915A (es) | 2018-12-12 | 2021-08-24 | Chemocentryx Inc | Inhibidores de cxcr7 para el tratamiento de cancer. |
| CN111593022B (zh) * | 2018-12-27 | 2023-10-24 | 广州溯原生物科技股份有限公司 | vMIP-Ⅱ诱导CD8+ T细胞去磷酸化为Tcm及其在药物中的应用 |
| EP4326257A4 (en) | 2021-04-19 | 2025-03-12 | ChemoCentryx, Inc. | AZETIDINYLACETAMIDES AS CXCR7 INHIBITORS |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006515854A (ja) * | 2002-12-20 | 2006-06-08 | ケモセントリックス, インコーポレイテッド | ヒト腫瘍発現ccxckr2の阻害剤 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020166133A1 (en) * | 1998-02-10 | 2002-11-07 | Millennium Pharmaceuticals, Inc | Neokine protein and nucleic acid molecules and uses therefor |
| JP2002506830A (ja) * | 1998-03-13 | 2002-03-05 | ザ ユニバーシティ オブ ブリティッシュ コロンビア | 治療的ケモカイン受容体アンタゴニスト |
| US20020107195A1 (en) * | 1998-07-21 | 2002-08-08 | Smithkline Beecham Corporation | Method for inducing chemotaxis in endothelial cells by administering stromal cell derived factor-1alpha |
| DE60137435D1 (de) * | 2000-09-15 | 2009-03-05 | Anormed Inc | Chemokin rezeptor bindenden heterozyklische verbindungen |
| US20040157818A1 (en) * | 2001-05-24 | 2004-08-12 | Mikiro Yanaka | Cxcr4-antagonistic drugs composed of nitrogen-containing compound |
| US7253007B2 (en) * | 2001-11-30 | 2007-08-07 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
| WO2004062591A2 (en) * | 2003-01-06 | 2004-07-29 | Oregon Health And Science University | Methods of treatment and diagnosis of kaposi's sarcoma (ks) and ks related diseases |
-
2005
- 2005-02-02 WO PCT/US2005/003521 patent/WO2005074645A2/en not_active Ceased
- 2005-02-02 AU AU2005209921A patent/AU2005209921B2/en not_active Ceased
- 2005-02-02 CA CA002554880A patent/CA2554880A1/en not_active Abandoned
- 2005-02-02 US US11/050,345 patent/US20050214287A1/en not_active Abandoned
- 2005-02-02 JP JP2006552252A patent/JP4916889B2/ja not_active Expired - Fee Related
- 2005-02-02 EP EP05726389A patent/EP1715892A4/en not_active Withdrawn
-
2006
- 2006-07-26 IL IL177104A patent/IL177104A/en active IP Right Grant
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006515854A (ja) * | 2002-12-20 | 2006-06-08 | ケモセントリックス, インコーポレイテッド | ヒト腫瘍発現ccxckr2の阻害剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| IL177104A (en) | 2010-12-30 |
| WO2005074645A3 (en) | 2005-12-22 |
| JP2007520564A (ja) | 2007-07-26 |
| EP1715892A2 (en) | 2006-11-02 |
| AU2005209921B2 (en) | 2011-04-07 |
| US20050214287A1 (en) | 2005-09-29 |
| EP1715892A4 (en) | 2008-07-09 |
| WO2005074645A2 (en) | 2005-08-18 |
| AU2005209921A1 (en) | 2005-08-18 |
| CA2554880A1 (en) | 2005-08-18 |
| IL177104A0 (en) | 2006-12-10 |
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