SG11202105889YA - Cxcr7 inhibitors for the treatment of cancer - Google Patents

Cxcr7 inhibitors for the treatment of cancer

Info

Publication number
SG11202105889YA
SG11202105889YA SG11202105889YA SG11202105889YA SG11202105889YA SG 11202105889Y A SG11202105889Y A SG 11202105889YA SG 11202105889Y A SG11202105889Y A SG 11202105889YA SG 11202105889Y A SG11202105889Y A SG 11202105889YA SG 11202105889Y A SG11202105889Y A SG 11202105889YA
Authority
SG
Singapore
Prior art keywords
cancer
treatment
cxcr7
inhibitors
cxcr7 inhibitors
Prior art date
Application number
SG11202105889YA
Inventor
Noriko Gotoh
James J Campbell
Original Assignee
Chemocentryx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemocentryx Inc filed Critical Chemocentryx Inc
Publication of SG11202105889YA publication Critical patent/SG11202105889YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
SG11202105889YA 2018-12-12 2019-12-11 Cxcr7 inhibitors for the treatment of cancer SG11202105889YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862778605P 2018-12-12 2018-12-12
PCT/US2019/065600 WO2020123582A1 (en) 2018-12-12 2019-12-11 Cxcr7 inhibitors for the treatment of cancer

Publications (1)

Publication Number Publication Date
SG11202105889YA true SG11202105889YA (en) 2021-07-29

Family

ID=71073777

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202105889YA SG11202105889YA (en) 2018-12-12 2019-12-11 Cxcr7 inhibitors for the treatment of cancer

Country Status (13)

Country Link
US (2) US11464786B2 (en)
EP (1) EP3893882A4 (en)
JP (1) JP2022512367A (en)
KR (1) KR20210102338A (en)
CN (1) CN113194956A (en)
AU (1) AU2019398198A1 (en)
BR (1) BR112021011222A2 (en)
CA (1) CA3122100A1 (en)
IL (1) IL283885A (en)
MA (1) MA54465A (en)
MX (1) MX2021006915A (en)
SG (1) SG11202105889YA (en)
WO (1) WO2020123582A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102196374B1 (en) 2012-11-29 2020-12-31 케모센트릭스, 인크. Cxcr7 antagonists
AU2019398198A1 (en) * 2018-12-12 2021-07-08 Chemocentryx, Inc. CXCR7 inhibitors for the treatment of cancer

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS536156B2 (en) 1972-10-30 1978-03-04
ES2271967T3 (en) 1996-03-29 2007-04-16 Duphar International Research B.V PIPERAZINE AND PIPERIDINE COMPOUNDS.
WO2001002392A1 (en) 1999-06-30 2001-01-11 Bristol-Myers Squibb Company Heterocyclic aminopyrrolidine derivatives as melatonergic agents
BR0112631A (en) 2000-07-20 2003-09-23 Neurogen Corp A compound or a pharmaceutically acceptable salt thereof, pharmaceutical composition, package, methods of reducing the calcium conductance of a capsaicin receptor and treating a mammal and use of a compound.
DK1399483T3 (en) 2001-01-05 2010-08-02 Pfizer Antibodies to insulin-like growth factor receptor I
WO2002094799A2 (en) 2001-05-22 2002-11-28 Neurogen Corporation Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues
US7169750B2 (en) 2001-07-31 2007-01-30 Anormed, Inc. Methods to mobilize progenitor/stem cells
US7871619B2 (en) 2001-11-30 2011-01-18 Chemocentryx, Inc. Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
ES2322252T3 (en) 2002-03-13 2009-06-18 Janssen Pharmaceutica Nv AMINODERIVED AS NEW HISTONA-DEACETILASA INHIBITORS.
WO2004009587A1 (en) 2002-07-22 2004-01-29 Orchid Chemicals & Pharmaceuticals Ltd Oxazolidinone derivatives as antibacterial agents
JP2004203871A (en) 2002-12-13 2004-07-22 Yamanouchi Pharmaceut Co Ltd Medicinal composition
WO2005023771A1 (en) 2003-09-05 2005-03-17 Ono Pharmaceutical Co., Ltd. Chemokine receptor antagonist and medical use thereof
WO2005074535A2 (en) 2004-01-30 2005-08-18 Eisai Co., Ltd. Cholinesterase inhibitors for spinal cord disorders
WO2005074645A2 (en) 2004-02-03 2005-08-18 Chemocentryx, Inc. Methods and compositions for modulating angiogenesis
AU2006230674A1 (en) 2004-03-18 2006-11-16 The Brigham And Women's Hospital, Inc. Methods for the Treatment of Synucleinopathies
EP1637529A1 (en) 2004-09-20 2006-03-22 4Sc Ag Novel piperidin-4-yl-thiazole-carboxamide analogues as inhibitors of T-cell proliferation and uses thereof
US7601745B2 (en) 2004-09-27 2009-10-13 4Sc Ag Heterocyclic NF-kB inhibitors
US7417062B2 (en) 2004-09-29 2008-08-26 Chemocentryx, Inc. Substituted arylamides
WO2006100461A1 (en) 2005-03-23 2006-09-28 Astrazeneca Ab 2-AZETIDINYL-4-(lH-PYRAZOL-3-YLAMINO)PYRIMIDINES AS INHIBITORS OF INSULIN-LIKE GROWTH FACTOR-I RECEPTOR ACTIVITY
AU2006263657A1 (en) 2005-06-29 2007-01-04 Chemocentryx, Inc. Substituted N-cinnamyl benzamides
WO2007059108A2 (en) 2005-11-10 2007-05-24 Chemocentryx, Inc. Substituted quinolones and methods of use
US8173365B2 (en) * 2006-03-24 2012-05-08 The University Of Tokyo Method for inhibiting signal transduction, signal transduction inhibitor to be used therein and use thereof
CA2647678A1 (en) 2006-03-29 2007-11-08 Merck & Co., Inc. Diazepan orexin receptor antagonists
WO2007115232A2 (en) 2006-03-30 2007-10-11 Chemocentryx, Inc. Cxcr4 modulators
WO2007115231A2 (en) 2006-03-30 2007-10-11 Chemocentryx, Inc. Cxcr4 modulators
AU2007272855B2 (en) 2006-07-14 2013-08-01 Merck Sharp & Dohme Corp. Substituted diazepan orexin receptor antagonists
BRPI0714440A2 (en) 2006-07-21 2013-04-24 Irm Llc itpkb inhibitor compound, use thereof and pharmaceutical composition
WO2008020229A2 (en) 2006-08-17 2008-02-21 Astrazeneca Ab Antibacterial pyrrolecarboxamides
US8088895B2 (en) 2006-10-18 2012-01-03 Chemocentryx, Inc. Antibodies that bind CXCR7 epitopes
PE20081229A1 (en) 2006-12-01 2008-08-28 Merck & Co Inc DIAZEPAM OREXIN RECEPTOR ANTAGONISTS REPLACED
CN101679297B (en) 2006-12-08 2012-01-11 埃克塞利希斯股份有限公司 LXR and FXR modulators
TW200833711A (en) 2006-12-22 2008-08-16 Genentech Inc Antibodies to insulin-like growth factor receptor
US20080293711A1 (en) 2007-03-08 2008-11-27 Clark Michael P Chemokine receptor modulators
TW200944523A (en) 2008-02-08 2009-11-01 Organon Nv (Dihydro)pyrrolo[2,1-a]isoquinolines
MX2011004490A (en) 2008-11-04 2011-07-20 Chemocentryx Inc Modulators of cxcr7.
US8853202B2 (en) * 2008-11-04 2014-10-07 Chemocentryx, Inc. Modulators of CXCR7
GB0822981D0 (en) 2008-12-17 2009-01-21 Summit Corp Plc Compounds for treatment of duchenne muscular dystrophy
CN103119045B (en) 2010-08-20 2016-02-17 和记黄埔医药(上海)有限公司 Pyrrolopyrimidine compounds and uses thereof
AU2011302196B2 (en) * 2010-09-14 2016-04-28 Exelixis, Inc. Inhibitors of PI3K-delta and methods of their use and manufacture
GB201017345D0 (en) 2010-10-14 2010-11-24 Proximagen Ltd Receptor antagonists
WO2012142164A1 (en) 2011-04-12 2012-10-18 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
CN103732592A (en) 2011-04-21 2014-04-16 默沙东公司 Insulin-like growth factor-1 receptor inhibitors
KR102196374B1 (en) 2012-11-29 2020-12-31 케모센트릭스, 인크. Cxcr7 antagonists
US9260527B2 (en) 2013-03-15 2016-02-16 Sdix, Llc Anti-human CXCR4 antibodies and methods of making same
AU2019398198A1 (en) * 2018-12-12 2021-07-08 Chemocentryx, Inc. CXCR7 inhibitors for the treatment of cancer

Also Published As

Publication number Publication date
WO2020123582A1 (en) 2020-06-18
EP3893882A1 (en) 2021-10-20
BR112021011222A2 (en) 2021-08-24
MA54465A (en) 2021-10-20
MX2021006915A (en) 2021-08-24
US20200188410A1 (en) 2020-06-18
US11464786B2 (en) 2022-10-11
IL283885A (en) 2021-07-29
JP2022512367A (en) 2022-02-03
EP3893882A4 (en) 2022-08-31
AU2019398198A1 (en) 2021-07-08
KR20210102338A (en) 2021-08-19
CN113194956A (en) 2021-07-30
CA3122100A1 (en) 2020-06-18
US20230100102A1 (en) 2023-03-30

Similar Documents

Publication Publication Date Title
EP3781564C0 (en) Pyridazine derivatives for the treatment of cancer
HK1247202A1 (en) Compounds for the treatment of cancer
EP3548071A4 (en) Methods for treatment of cancer comprising tigit-binding agents
IL264674B1 (en) Anti-siglec-7 antibodies for the treatment of cancer
IL279260A (en) Kdm1a inhibitors for the treatment of disease
IL275496A (en) Glycolate oxidase inhibitors for the treatment of disease
IL261047A (en) Taf1 inhibitors for the therapy of cancer
IL268676A (en) Inhibition of smarca2 for treatment of cancer
SG11202011117VA (en) Treatment of cancer
EP3503887A4 (en) Combinations for the treatment of cancer
EP3490561A4 (en) Combinations for the treatment of cancer
SG11202010793UA (en) Methods of treating cancer
IL274198A (en) Use of nox inhibitors for treatment of cancer
IL285807A (en) Immunotherapy for the treatment of cancer
EP3630080A4 (en) Use of ezh2 inhibitors for treating cancer
IL283885A (en) Cxcr7 inhibitors for the treatment of cancer
EP3548007A4 (en) Methods for the treatment of cancer
IL288522A (en) Egfr inhibitor for the treatment of cancer
ZA201901578B (en) Combinations including abx196 for the treatment of cancer
EP3285769A4 (en) Selective pfkfb4 inhibitors for the treatment of cancer
IL281600A (en) Methods of treating cancer
IL277981A (en) Methods of treating cancer
IL282313A (en) Abituzumab for the treatment of colorectal cancer
EP3630754B8 (en) Isoindoline-acetylene compounds for the treatment of cancer
EP3615052A4 (en) Use of hcn inhibitors for treatment of cancer