JP4896135B2 - 髄核用ヒドロゲルバルーンプロテーゼ - Google Patents
髄核用ヒドロゲルバルーンプロテーゼ Download PDFInfo
- Publication number
- JP4896135B2 JP4896135B2 JP2008528212A JP2008528212A JP4896135B2 JP 4896135 B2 JP4896135 B2 JP 4896135B2 JP 2008528212 A JP2008528212 A JP 2008528212A JP 2008528212 A JP2008528212 A JP 2008528212A JP 4896135 B2 JP4896135 B2 JP 4896135B2
- Authority
- JP
- Japan
- Prior art keywords
- prosthesis
- hydrogel
- poly
- aqueous solution
- nucleus pulposus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/441—Joints for the spine, e.g. vertebrae, spinal discs made of inflatable pockets or chambers filled with fluid, e.g. with hydrogel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
- A61F2002/444—Intervertebral or spinal discs, e.g. resilient for replacing the nucleus pulposus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Jellies, Jams, And Syrups (AREA)
- Colloid Chemistry (AREA)
Description
Claims (8)
- 椎間板の髄核を置換し又は補充するためのプロテーゼであって、
内部キャビティを構成する可撓性の壁を備えるように予め形成された拡張可能なバルーンを有し、前記可撓性の壁は、0.02mm〜1.00mmの厚さを有し、
更に、前記プロテーゼが充填可能であるように、前記可撓性の壁を通して前記内部キャビティと連通する充填チューブを有し、
前記予め形成された拡張可能なバルーンは、カニューレの中を通して椎間板の中に挿入されるように構成され、
前記可撓性の壁は、ポリ(ビニルアルコール)を含む水溶液が凍結及び解凍サイクルを繰返し受けることによって作られるクライオゲルを含む材料で形成され、
前記予め形成された拡張可能なバルーンは、前記充填チューブを介して生体適合性材料で充填されて拡張形態になり、前記生体適合性材料は、生体適合性液体、生体適合性ポリマー及び生体適合性ヒドロゲルからなる群から選択され、
前記プロテーゼは、30%歪み時に、0.02MPa〜0.8MPaの引張り弾性係数を有する、プロテーゼ。 - 前記クライオゲルは、更にポリ(ビニルピロリドン)を含む水溶液から形成される、請求項1に記載のプロテーゼ。
- 拡張されたときに、生来の髄核の形状にほぼ一致する形状を有する、請求項1に記載のプロテーゼ。
- 前記生体適合性ヒドロゲルは、熱ゲル化性ヒドロゲルである、請求項1に記載のプロテーゼ。
- 前記熱ゲル化性ヒドロゲルは、ポリ(N−イソプロピルアクリルアミド)を含む第1の水溶液と、ポリ(ビニルアルコール)を含む第2の水溶液との混合物から作られる、請求項4に記載のプロテーゼ。
- 前記熱ゲル化性ヒドロゲルは、ポリ(N−イソプロピルアクリルアミド)を含む第1の水溶液と、ポリ(エチレングリコール)を含む第2の水溶液との混合物から作られる、請求項4に記載のプロテーゼ。
- 前記熱ゲル化性ヒドロゲルは、ポリ(N−イソプロピルアクリルアミド)−グラフトポリ(エチレングリコール)ポリマーを含む水溶液から作られる、請求項4に記載のプロテーゼ。
- 前記熱ゲル化性ヒドロゲルは、ポリ(エチレングリコール)−ポリ(N−イソプロピルアクリルアミド)−ポリ(エチレングリコール)トリブロックポリマーを含む水溶液から作られる、請求項4に記載のプロテーゼ。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71143005P | 2005-08-26 | 2005-08-26 | |
US60/711,430 | 2005-08-26 | ||
PCT/US2006/033276 WO2007025164A2 (en) | 2005-08-26 | 2006-08-25 | Hydrogel balloon prosthesis for nucleus pulposus |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2009505750A JP2009505750A (ja) | 2009-02-12 |
JP2009505750A5 JP2009505750A5 (ja) | 2009-10-08 |
JP4896135B2 true JP4896135B2 (ja) | 2012-03-14 |
Family
ID=37772444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008528212A Expired - Fee Related JP4896135B2 (ja) | 2005-08-26 | 2006-08-25 | 髄核用ヒドロゲルバルーンプロテーゼ |
Country Status (15)
Country | Link |
---|---|
US (2) | US8287595B2 (ja) |
EP (1) | EP1917050B1 (ja) |
JP (1) | JP4896135B2 (ja) |
KR (1) | KR20080036217A (ja) |
CN (1) | CN101365500B (ja) |
AT (1) | ATE464076T1 (ja) |
AU (1) | AU2006282883A1 (ja) |
BR (1) | BRPI0615391A2 (ja) |
CA (1) | CA2620239A1 (ja) |
DE (1) | DE602006013649D1 (ja) |
ES (1) | ES2340526T3 (ja) |
NZ (1) | NZ566184A (ja) |
PL (1) | PL1917050T3 (ja) |
WO (1) | WO2007025164A2 (ja) |
ZA (1) | ZA200802596B (ja) |
Families Citing this family (84)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030008396A1 (en) * | 1999-03-17 | 2003-01-09 | Ku David N. | Poly(vinyl alcohol) hydrogel |
EP1253854A4 (en) | 1999-03-07 | 2010-01-06 | Discure Ltd | METHOD AND APPARATUS FOR COMPUTERIZED SURGERY |
CA2549329A1 (en) * | 2000-08-30 | 2002-03-07 | Sdgi Holdings, Inc. | Intervertebral disc nucleus implants and methods |
NZ539779A (en) * | 2002-11-05 | 2009-01-31 | Spineology Inc | A semi-biological intervertebral disc replacement system created by inserting tissue promoting material into a cavity in the disc |
US7910124B2 (en) | 2004-02-06 | 2011-03-22 | Georgia Tech Research Corporation | Load bearing biocompatible device |
WO2005077013A2 (en) | 2004-02-06 | 2005-08-25 | Georgia Tech Research Corporation | Surface directed cellular attachment |
US20050278025A1 (en) * | 2004-06-10 | 2005-12-15 | Salumedica Llc | Meniscus prosthesis |
US7955339B2 (en) * | 2005-05-24 | 2011-06-07 | Kyphon Sarl | Low-compliance expandable medical device |
US20070042326A1 (en) * | 2005-06-01 | 2007-02-22 | Osseous Technologies Of America | Collagen antral membrane expander |
NZ566184A (en) * | 2005-08-26 | 2010-07-30 | Synthes Gmbh | Hydrogel balloon prosthesis for nucleus pulposus |
US11896505B2 (en) * | 2005-10-31 | 2024-02-13 | Scott M. Epstein | Methods for making and using a structural hydrogel polymer device |
US8577469B2 (en) * | 2006-07-12 | 2013-11-05 | Rainbow Medical Ltd. | Iontophoretic and electroosmotic disc treatment |
US7758649B2 (en) * | 2006-08-04 | 2010-07-20 | Integrity Intellect Inc. | Reversibly deformable implant |
US8029569B2 (en) * | 2006-11-20 | 2011-10-04 | International Spinal Innovations, Llc | Implantable spinal disk |
US20080161929A1 (en) | 2006-12-29 | 2008-07-03 | Mccormack Bruce | Cervical distraction device |
US9005288B2 (en) | 2008-01-09 | 2015-04-14 | Providence Medical Techonlogy, Inc. | Methods and apparatus for accessing and treating the facet joint |
CA2719490A1 (en) * | 2008-03-28 | 2009-10-01 | Spineology Inc. | Method and device for interspinous process fusion |
US7976578B2 (en) * | 2008-06-04 | 2011-07-12 | James Marvel | Buffer for a human joint and method of arthroscopically inserting |
US9381049B2 (en) | 2008-06-06 | 2016-07-05 | Providence Medical Technology, Inc. | Composite spinal facet implant with textured surfaces |
US9333086B2 (en) | 2008-06-06 | 2016-05-10 | Providence Medical Technology, Inc. | Spinal facet cage implant |
CA2725811A1 (en) | 2008-06-06 | 2009-12-10 | Providence Medical Technology, Inc. | Facet joint implants and delivery tools |
US8361152B2 (en) | 2008-06-06 | 2013-01-29 | Providence Medical Technology, Inc. | Facet joint implants and delivery tools |
WO2010030994A2 (en) | 2008-06-06 | 2010-03-18 | Providence Medical Technology, Inc. | Cervical distraction/implant delivery device |
US8267966B2 (en) | 2008-06-06 | 2012-09-18 | Providence Medical Technology, Inc. | Facet joint implants and delivery tools |
US11224521B2 (en) | 2008-06-06 | 2022-01-18 | Providence Medical Technology, Inc. | Cervical distraction/implant delivery device |
AU2014240268B2 (en) * | 2008-09-05 | 2016-10-13 | Cardiopolymers, Inc. | Apparatus and method for capsule formation in tissue |
AU2009289484B2 (en) * | 2008-09-05 | 2014-10-23 | Cardiopolymers, Inc | Apparatus and method for capsule formation in tissue |
US8187333B2 (en) * | 2008-09-18 | 2012-05-29 | Mayer Peter L | Intervertebral disc prosthesis and method for implanting and explanting |
US8814937B2 (en) | 2008-09-18 | 2014-08-26 | Peter L. Mayer | Intervertebral disc prosthesis, method for assembling, method for implanting prosthesis, and method for explanting |
CA2748337A1 (en) * | 2008-12-29 | 2010-07-08 | Synthes (U.S.A.) | A method of forming and the resulting membrane composition for surgical site preservation |
US8636803B2 (en) | 2009-04-07 | 2014-01-28 | Spinal Stabilization Technologies, Llc | Percutaneous implantable nuclear prosthesis |
US8394125B2 (en) * | 2009-07-24 | 2013-03-12 | Zyga Technology, Inc. | Systems and methods for facet joint treatment |
EP2674121A4 (en) * | 2011-02-11 | 2017-01-25 | Terumo Kabushiki Kaisha | Interspinous process spacing device |
CA3048443C (en) | 2011-05-26 | 2021-01-05 | Cartiva, Inc. | Tapered joint implant and related tools |
US9393126B2 (en) | 2012-04-20 | 2016-07-19 | Peter L. Mayer | Bilaterally placed disc prosthesis for spinal implant and method of bilateral placement |
US9364339B2 (en) | 2012-04-30 | 2016-06-14 | Peter L. Mayer | Unilaterally placed expansile spinal prosthesis |
US9095443B2 (en) | 2012-05-08 | 2015-08-04 | Eric R. VonGunten | Nucleus pulposus spinal implant and method of using the same |
US10350072B2 (en) | 2012-05-24 | 2019-07-16 | Cartiva, Inc. | Tooling for creating tapered opening in tissue and related methods |
USD732667S1 (en) | 2012-10-23 | 2015-06-23 | Providence Medical Technology, Inc. | Cage spinal implant |
USD745156S1 (en) | 2012-10-23 | 2015-12-08 | Providence Medical Technology, Inc. | Spinal implant |
WO2014105972A1 (en) * | 2012-12-26 | 2014-07-03 | Koss Scott A | Apparatus, kit, and method for percutaneous intervertebral disc restoration |
US9192420B2 (en) * | 2013-01-24 | 2015-11-24 | Kyphon Sarl | Surgical system and methods of use |
US9295479B2 (en) | 2013-03-14 | 2016-03-29 | Spinal Stabilization Technologies, Llc | Surgical device |
US20140277467A1 (en) | 2013-03-14 | 2014-09-18 | Spinal Stabilization Technologies, Llc | Prosthetic Spinal Disk Nucleus |
US9731122B2 (en) | 2013-04-29 | 2017-08-15 | Rainbow Medical Ltd. | Electroosmotic tissue treatment |
RU2561120C1 (ru) * | 2014-03-13 | 2015-08-20 | Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) | Способ формования криогелей поливинилового спирта |
US9610150B2 (en) * | 2014-03-18 | 2017-04-04 | Boston Scientific Scimed, Inc. | Devices for sizing a cavity to fit an organ and related methods of use |
US20150342648A1 (en) | 2014-05-27 | 2015-12-03 | Bruce M. McCormack | Lateral mass fixation implant |
JP2017520357A (ja) | 2014-05-28 | 2017-07-27 | プロビデンス メディカル テクノロジー インコーポレイテッド | 外側塊固定システム |
US9873769B2 (en) | 2014-07-10 | 2018-01-23 | Cambridge Polymer Group, Inc. | Thiolated PEG-PVA hydrogels |
US10786360B2 (en) | 2014-11-04 | 2020-09-29 | Spinal Stabilization Technologies Llc | Percutaneous implantable nuclear prosthesis |
WO2016073568A1 (en) | 2014-11-04 | 2016-05-12 | Spinal Stabilization Technologies Llc | Percutaneous implantable nuclear prosthesis |
EP3636226A1 (en) | 2015-03-31 | 2020-04-15 | Cartiva, Inc. | Carpometacarpal (cmc) implants |
CA2981061A1 (en) | 2015-03-31 | 2016-10-06 | Cartiva, Inc. | Hydrogel implants with porous materials and methods |
US9616221B2 (en) | 2015-07-08 | 2017-04-11 | Rainbow Medical Ltd. | Electrical treatment of Alzheimer's disease |
JP6891176B2 (ja) | 2015-09-01 | 2021-06-18 | スパイナル スタビライゼーション テクノロジーズ リミテッド ライアビリティ カンパニー | 埋込み可能な髄核プロテーゼ |
USD841165S1 (en) | 2015-10-13 | 2019-02-19 | Providence Medical Technology, Inc. | Cervical cage |
EP3361966A4 (en) | 2015-10-13 | 2019-07-24 | Providence Medical Technology, Inc. | METHOD AND SYSTEM FOR INSERTING AN ANGLE JOINT IMPLANT |
US10898716B2 (en) | 2015-10-29 | 2021-01-26 | Rainbow Medical Ltd. | Electrical substance clearance from the brain |
US9724515B2 (en) | 2015-10-29 | 2017-08-08 | Rainbow Medical Ltd. | Electrical substance clearance from the brain for treatment of Alzheimer's disease |
US11484706B2 (en) | 2015-12-29 | 2022-11-01 | Discure Technologies Ltd | Disc therapy |
US10518085B2 (en) | 2015-12-29 | 2019-12-31 | Rainbow Medical Ltd. | Disc therapy |
US9950156B2 (en) | 2016-09-13 | 2018-04-24 | Rainbow Medical Ltd. | Disc therapy |
US9770591B2 (en) | 2015-12-29 | 2017-09-26 | Rainbow Medical Ltd. | Disc therapy |
US11179493B2 (en) | 2016-04-07 | 2021-11-23 | Rowan University | Methods and compositions for inducing multi-targeted healing of intervertebral disc defects |
JP2019519334A (ja) | 2016-06-28 | 2019-07-11 | プロビデンス メディカル テクノロジー インコーポレイテッド | 脊椎インプラント及び脊椎インプラントの使用方法 |
USD887552S1 (en) | 2016-07-01 | 2020-06-16 | Providence Medical Technology, Inc. | Cervical cage |
CN108211067B (zh) * | 2016-12-22 | 2020-11-17 | 宜鑫兴业有限公司 | 气道装置 |
US10569086B2 (en) | 2017-01-11 | 2020-02-25 | Rainbow Medical Ltd. | Electrical microglial cell activation |
US10758722B2 (en) | 2017-05-03 | 2020-09-01 | Rainbow Medical Ltd. | Electrical treatment of Parkinson's disease |
US11871968B2 (en) | 2017-05-19 | 2024-01-16 | Providence Medical Technology, Inc. | Spinal fixation access and delivery system |
WO2019136263A1 (en) | 2018-01-04 | 2019-07-11 | Providence Medical Technology, Inc. | Facet screw and delivery device |
EP3737338B1 (en) | 2018-01-12 | 2024-04-10 | Percheron Spine, LLC | Spinal disc implant and device and method for percutaneous delivery of the spinal disc implant |
WO2019175879A1 (en) | 2018-03-14 | 2019-09-19 | Rainbow Medical Ltd. | Electrical substance clearance from the brain |
EP3829468A4 (en) | 2018-09-04 | 2022-08-10 | Spinal Stabilization Technologies LLC | IMPLANTABLE NUCLEAR PROSTHESIS, KITS AND RELATED PROCEDURES |
USD933230S1 (en) | 2019-04-15 | 2021-10-12 | Providence Medical Technology, Inc. | Cervical cage |
USD911525S1 (en) | 2019-06-21 | 2021-02-23 | Providence Medical Technology, Inc. | Spinal cage |
US11123197B2 (en) * | 2019-09-03 | 2021-09-21 | Rainbow Medical Ltd. | Hydropneumatic artificial intervertebral disc |
EP3791831A1 (de) | 2019-09-10 | 2021-03-17 | AIT Austrian Institute of Technology GmbH | Implantat zur behandlung einer bandscheibe |
US10881858B1 (en) | 2019-09-18 | 2021-01-05 | Rainbow Medical Ltd. | Electrical substance clearance from the brain |
USD945621S1 (en) | 2020-02-27 | 2022-03-08 | Providence Medical Technology, Inc. | Spinal cage |
US11298530B1 (en) | 2021-05-03 | 2022-04-12 | Discure Technologies Ltd. | Synergistic therapies for intervertebral disc degeneration |
US11344721B1 (en) | 2021-08-16 | 2022-05-31 | Rainbow Medical Ltd. | Cartilage treatment |
US11413455B1 (en) | 2022-02-08 | 2022-08-16 | Rainbow Medical Ltd. | Electrical treatment of Alzheimer's disease |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09313593A (ja) * | 1996-05-31 | 1997-12-09 | Kanegafuchi Chem Ind Co Ltd | カテーテルバルーン及びその製造方法 |
JP2003038637A (ja) * | 1997-05-05 | 2003-02-12 | Georgia Tech Research Corp | ポリ(ビニルアルコール)クリオゲル |
JP2003513685A (ja) * | 1999-10-29 | 2003-04-15 | ドレクセル・ユニバーシティー | 椎間板における髄核置換のための会合性ヒドロゲル |
JP2004507318A (ja) * | 2000-08-30 | 2004-03-11 | エスディージーアイ・ホールディングス・インコーポレーテッド | 椎間板髄核インプラント及び方法 |
WO2004052248A1 (en) * | 2002-12-07 | 2004-06-24 | Sdgi Holdings, Inc. | Method and apparatus for intervertebal disc expansion |
WO2004098756A2 (en) * | 2003-04-30 | 2004-11-18 | Drexel University | Thermogelling polymer blends for biomaterial applications |
WO2005023150A2 (en) * | 2003-09-09 | 2005-03-17 | Spinemedica Corp. | Flexible spinal disc |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5047055A (en) * | 1990-12-21 | 1991-09-10 | Pfizer Hospital Products Group, Inc. | Hydrogel intervertebral disc nucleus |
US5192326A (en) * | 1990-12-21 | 1993-03-09 | Pfizer Hospital Products Group, Inc. | Hydrogel bead intervertebral disc nucleus |
US5260066A (en) * | 1992-01-16 | 1993-11-09 | Srchem Incorporated | Cryogel bandage containing therapeutic agent |
US5534028A (en) * | 1993-04-20 | 1996-07-09 | Howmedica, Inc. | Hydrogel intervertebral disc nucleus with diminished lateral bulging |
ATE203885T1 (de) * | 1994-09-08 | 2001-08-15 | Stryker Technologies Corp | Bandscheibenkern aus hydrogel |
US5824093A (en) * | 1994-10-17 | 1998-10-20 | Raymedica, Inc. | Prosthetic spinal disc nucleus |
US5531028A (en) * | 1994-11-16 | 1996-07-02 | Flippen; James | Printed sheet measuring device |
US5863551A (en) * | 1996-10-16 | 1999-01-26 | Organogel Canada Ltee | Implantable polymer hydrogel for therapeutic uses |
FR2788008B1 (fr) * | 1998-12-30 | 2001-03-23 | Inst Curie | Milieu thermosensible pour la separation electrocinetique d'especes au sein d'un canal de separation |
US7214245B1 (en) * | 1999-10-29 | 2007-05-08 | Drexel University | Associating hydrogels for nucleus pulposus replacement in intervertebral discs |
CA2427543A1 (en) * | 2000-03-15 | 2004-11-02 | Yu-Ling Cheng | Thermally reversible implant and filler |
US20020026244A1 (en) | 2000-08-30 | 2002-02-28 | Trieu Hai H. | Intervertebral disc nucleus implants and methods |
CA2429168C (en) * | 2000-11-15 | 2010-06-08 | Bio Syntech Canada Inc. | Method for restoring a damaged or degenerated intervertebral disc |
WO2002085262A1 (en) | 2001-04-24 | 2002-10-31 | Galley Geoffrey H | Surgical restoration of an intervertebral disc |
US7156877B2 (en) * | 2001-06-29 | 2007-01-02 | The Regents Of The University Of California | Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs |
WO2003043552A1 (en) * | 2001-11-16 | 2003-05-30 | Biocure, Inc. | Methods for initiating in situ formation of hydrogels |
CA2468908C (en) * | 2001-12-05 | 2009-03-31 | Mathys Medizinaltechnik Ag | Intervertebral disk prosthesis or nucleus replacement prosthesis |
ES2287251T3 (es) * | 2002-04-04 | 2007-12-16 | Synthes Gmbh | Protesis del disco intervertebral o protesis de reemplazo del nucleo. |
JP2004007318A (ja) | 2002-06-03 | 2004-01-08 | Matsushita Electric Ind Co Ltd | テレビジョン受像機におけるチャンネル切り換え法 |
US20040016648A1 (en) | 2002-07-24 | 2004-01-29 | Applied Materials, Inc. | Tilted electrochemical plating cell with constant wafer immersion angle |
US6932843B2 (en) * | 2002-09-25 | 2005-08-23 | Medicinelodge, Inc. | Apparatus and method for the in-situ formation of a structural prosthesis |
US20040078090A1 (en) * | 2002-10-18 | 2004-04-22 | Francois Binette | Biocompatible scaffolds with tissue fragments |
WO2005032358A2 (en) * | 2003-10-02 | 2005-04-14 | Endius, Inc. | Methods, systems and apparatuses for performing minimally invasive spinal procedures |
KR101166178B1 (ko) | 2004-05-21 | 2012-07-18 | 신세스 게엠바하 | 하이드로겔을 사용한 수핵의 대체 또는 보충 |
DE102004030347B4 (de) * | 2004-06-18 | 2006-08-03 | Aesculap Ag & Co. Kg | Implantat |
JP2008508980A (ja) * | 2004-08-09 | 2008-03-27 | トランス1,インク. | 髄核補綴装置および方法 |
AU2006203985A1 (en) * | 2005-01-05 | 2006-07-13 | Philadelphia Health And Education Corporation | Delivery vehicles, bioactive substances and viral vaccines |
CN101184457A (zh) | 2005-03-29 | 2008-05-21 | 新特斯有限责任公司 | 植入用于髓核的水凝胶假体的方法和设备 |
US7182783B2 (en) * | 2005-04-25 | 2007-02-27 | Sdgi Holdings, Inc. | Selectively expandable composite structures for spinal arthroplasty |
US20060293561A1 (en) * | 2005-06-24 | 2006-12-28 | Abay Eustaquio O Ii | System and methods for intervertebral disc surgery |
NZ566184A (en) * | 2005-08-26 | 2010-07-30 | Synthes Gmbh | Hydrogel balloon prosthesis for nucleus pulposus |
-
2006
- 2006-08-25 NZ NZ566184A patent/NZ566184A/en unknown
- 2006-08-25 US US11/510,747 patent/US8287595B2/en active Active
- 2006-08-25 EP EP06813765A patent/EP1917050B1/en active Active
- 2006-08-25 BR BRPI0615391-7A patent/BRPI0615391A2/pt active Search and Examination
- 2006-08-25 AU AU2006282883A patent/AU2006282883A1/en not_active Abandoned
- 2006-08-25 JP JP2008528212A patent/JP4896135B2/ja not_active Expired - Fee Related
- 2006-08-25 ZA ZA200802596A patent/ZA200802596B/xx unknown
- 2006-08-25 KR KR1020087005531A patent/KR20080036217A/ko not_active Application Discontinuation
- 2006-08-25 ES ES06813765T patent/ES2340526T3/es active Active
- 2006-08-25 CA CA002620239A patent/CA2620239A1/en not_active Abandoned
- 2006-08-25 CN CN2006800394346A patent/CN101365500B/zh not_active Expired - Fee Related
- 2006-08-25 PL PL06813765T patent/PL1917050T3/pl unknown
- 2006-08-25 AT AT06813765T patent/ATE464076T1/de active
- 2006-08-25 WO PCT/US2006/033276 patent/WO2007025164A2/en active Application Filing
- 2006-08-25 DE DE602006013649T patent/DE602006013649D1/de active Active
-
2009
- 2009-10-29 US US12/608,565 patent/US20100047437A1/en not_active Abandoned
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09313593A (ja) * | 1996-05-31 | 1997-12-09 | Kanegafuchi Chem Ind Co Ltd | カテーテルバルーン及びその製造方法 |
JP2003038637A (ja) * | 1997-05-05 | 2003-02-12 | Georgia Tech Research Corp | ポリ(ビニルアルコール)クリオゲル |
JP2003513685A (ja) * | 1999-10-29 | 2003-04-15 | ドレクセル・ユニバーシティー | 椎間板における髄核置換のための会合性ヒドロゲル |
JP2004507318A (ja) * | 2000-08-30 | 2004-03-11 | エスディージーアイ・ホールディングス・インコーポレーテッド | 椎間板髄核インプラント及び方法 |
WO2004052248A1 (en) * | 2002-12-07 | 2004-06-24 | Sdgi Holdings, Inc. | Method and apparatus for intervertebal disc expansion |
WO2004098756A2 (en) * | 2003-04-30 | 2004-11-18 | Drexel University | Thermogelling polymer blends for biomaterial applications |
WO2005023150A2 (en) * | 2003-09-09 | 2005-03-17 | Spinemedica Corp. | Flexible spinal disc |
Also Published As
Publication number | Publication date |
---|---|
ZA200802596B (en) | 2009-03-25 |
CN101365500A (zh) | 2009-02-11 |
CA2620239A1 (en) | 2007-03-01 |
JP2009505750A (ja) | 2009-02-12 |
ATE464076T1 (de) | 2010-04-15 |
US20100047437A1 (en) | 2010-02-25 |
US20070073402A1 (en) | 2007-03-29 |
AU2006282883A1 (en) | 2007-03-01 |
PL1917050T3 (pl) | 2010-08-31 |
EP1917050B1 (en) | 2010-04-14 |
WO2007025164A2 (en) | 2007-03-01 |
DE602006013649D1 (en) | 2010-05-27 |
US8287595B2 (en) | 2012-10-16 |
WO2007025164A3 (en) | 2007-12-06 |
CN101365500B (zh) | 2013-01-16 |
BRPI0615391A2 (pt) | 2011-05-17 |
EP1917050A2 (en) | 2008-05-07 |
ES2340526T3 (es) | 2010-06-04 |
NZ566184A (en) | 2010-07-30 |
KR20080036217A (ko) | 2008-04-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP4896135B2 (ja) | 髄核用ヒドロゲルバルーンプロテーゼ | |
US7156877B2 (en) | Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs | |
JP3909049B2 (ja) | 放射線可視ヒドロゲル椎間円板核 | |
EP1626799B1 (en) | Thermogelling polymer blends for biomaterial applications | |
JP4347539B2 (ja) | 脊髄核移植 | |
JP2735517B2 (ja) | ヒドロゲル椎間円板核 | |
US20090112221A1 (en) | System and method for measuring the shape of internal body cavities | |
US20090234457A1 (en) | Systems, devices and methods for treatment of intervertebral disorders | |
US20060149380A1 (en) | Systems, devices and methods for treatment of intervertebral disorders | |
US20060206209A1 (en) | Prosthetic nucleus apparatus and methods | |
US20050287218A1 (en) | Biomaterial | |
JP2006515780A (ja) | 人工髄核およびその注入方法 | |
US20110189253A1 (en) | Biomaterial composition and method | |
WO2007133214A1 (en) | Prosthetic disc nuclear replacement and soft-tissue reconstruction devices |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20090818 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20090818 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20110519 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20110523 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20110822 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20110829 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20110926 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20111003 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20111021 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20111205 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20111220 |
|
R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20150106 Year of fee payment: 3 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
LAPS | Cancellation because of no payment of annual fees |