JP4860686B2 - 血液処理システムの遠心分離機 - Google Patents

血液処理システムの遠心分離機 Download PDF

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Publication number
JP4860686B2
JP4860686B2 JP2008505528A JP2008505528A JP4860686B2 JP 4860686 B2 JP4860686 B2 JP 4860686B2 JP 2008505528 A JP2008505528 A JP 2008505528A JP 2008505528 A JP2008505528 A JP 2008505528A JP 4860686 B2 JP4860686 B2 JP 4860686B2
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Japan
Prior art keywords
plasma
disk
blood
rbc
channel
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Expired - Fee Related
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JP2008505528A
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Japanese (ja)
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JP2008535575A (ja
JP2008535575A5 (enExample
Inventor
トーマス ロビンソン
トーマス ピー サヒネス
リチャード デリア
サルヴァドール エム ザモラ
ブライアン ディー ルイス
ロバート ケイ フェルナンデス
ヴィクター エイ ブリオネス
トーマス ノーランド マクナマラ
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テルモ メディカル コーポレイション
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Priority claimed from US11/102,215 external-priority patent/US20060226086A1/en
Application filed by テルモ メディカル コーポレイション filed Critical テルモ メディカル コーポレイション
Priority claimed from PCT/US2006/012867 external-priority patent/WO2006110470A1/en
Publication of JP2008535575A publication Critical patent/JP2008535575A/ja
Publication of JP2008535575A5 publication Critical patent/JP2008535575A5/ja
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • A61M1/0209Multiple bag systems for separating or storing blood components
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • A61M1/0209Multiple bag systems for separating or storing blood components
    • A61M1/0218Multiple bag systems for separating or storing blood components with filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • A61M1/0209Multiple bag systems for separating or storing blood components
    • A61M1/0231Multiple bag systems for separating or storing blood components with gas separating means, e.g. air outlet through microporous membrane or gas bag
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/30Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/30Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
    • A61M1/301Details
    • A61M1/303Details having a reservoir for treated blood to be returned
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/30Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
    • A61M1/301Details
    • A61M1/305Control of inversion point between collection and re-infusion phase
    • A61M1/308Volume control, e.g. with open or flexible containers, by counting the number of pump revolutions, weighing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3496Plasmapheresis; Leucopheresis; Lymphopheresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36222Details related to the interface between cassette and machine
    • A61M1/362223Details related to the interface between cassette and machine the interface being evacuated interfaces to enhance contact
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36222Details related to the interface between cassette and machine
    • A61M1/362227Details related to the interface between cassette and machine the interface providing means for actuating on functional elements of the cassette, e.g. plungers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36224Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit with sensing means or components thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36225Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit with blood pumping means or components thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362261Constructional details of cassettes, e.g. specific details on material or shape at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362265Details of valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362266Means for adding solutions or substances to the blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/12General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • External Artificial Organs (AREA)
  • Centrifugal Separators (AREA)
JP2008505528A 2005-04-08 2006-04-07 血液処理システムの遠心分離機 Expired - Fee Related JP4860686B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US11/102,215 US20060226086A1 (en) 2005-04-08 2005-04-08 Centrifuge for blood processing systems
US11/102,215 2005-04-08
US11/386,251 2006-03-22
US11/387,018 2006-03-22
US11/386,486 US20060226089A1 (en) 2005-04-08 2006-03-22 Method and apparatus for blood separations
US11/386,441 2006-03-22
US11/387,018 US20060226090A1 (en) 2005-04-08 2006-03-22 Method and apparatus for blood separations
US11/386,251 US20060226087A1 (en) 2005-04-08 2006-03-22 Method and apparatus for blood separations
US11/386,441 US20060226088A1 (en) 2005-04-08 2006-03-22 Disposable set for separations of blood into its components
US11/386,486 2006-03-22
PCT/US2006/012867 WO2006110470A1 (en) 2005-04-08 2006-04-07 Centrifuge for blood processing systems

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011172644A Division JP2011218218A (ja) 2005-04-08 2011-08-08 血液処理システムの遠心分離機

Publications (3)

Publication Number Publication Date
JP2008535575A JP2008535575A (ja) 2008-09-04
JP2008535575A5 JP2008535575A5 (enExample) 2009-05-28
JP4860686B2 true JP4860686B2 (ja) 2012-01-25

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JP2008505528A Expired - Fee Related JP4860686B2 (ja) 2005-04-08 2006-04-07 血液処理システムの遠心分離機
JP2011172644A Pending JP2011218218A (ja) 2005-04-08 2011-08-08 血液処理システムの遠心分離機

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US (1) US20060226087A1 (enExample)
JP (2) JP4860686B2 (enExample)

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DE102009026592B4 (de) 2009-05-29 2014-08-28 Sorin Group Deutschland Gmbh Vorrichtung zur Festlegung des venösen Zuflusses zu einem Blutreservoir eines extrakorporalen Blutkreislaufs
US12089589B2 (en) 2009-10-12 2024-09-17 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
EP2380611B1 (en) * 2010-04-20 2013-05-29 Sorin Group Italia S.r.l. Blood reservoir with level sensor
EP4091645A1 (en) 2010-08-25 2022-11-23 Hemanext Inc. Method for enhancing red blood cell quality and survival during storage
PT3539381T (pt) 2010-11-05 2023-09-26 Hemanext Inc Irradiação de glóbulos vermelhos e armazenamento anaeróbico
US9067004B2 (en) * 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
EP2545948B1 (en) 2011-07-12 2014-04-16 Sorin Group Italia S.r.l. Dual chamber blood reservoir
ES2742949T3 (es) 2011-08-10 2020-02-17 New Health Sciences Inc Dispositivo integrado de filtrado para el agotamiento de leucocitos, oxígeno y/o co2 y separación de plasma
EP2692373A1 (en) * 2012-08-02 2014-02-05 Debiotech S.A. Pressure measurement unit for determining fluid pressure within a medical fluid dispensing device
WO2014134503A1 (en) 2013-02-28 2014-09-04 New Health Sciences, Inc. Gas depletion and gas addition devices for blood treatment
DE102014103507A1 (de) * 2014-03-14 2015-09-17 Fresenius Medical Care Deutschland Gmbh Medizinische Funktionsvorrichtung mit einem Ventilsitz für ein remanentes Rückschlagventil
JP6409199B2 (ja) * 2014-07-22 2018-10-24 キョーラク株式会社 血液浄化回路パネル
CN106535955B (zh) * 2014-04-07 2019-07-19 京洛株式会社 中空成形品
EP3142719B1 (en) 2014-05-16 2019-11-06 Sorin Group Italia S.r.l. Blood reservoir with fluid volume measurement based on pressure sensor
CN107530377B (zh) 2015-03-10 2021-09-03 新健康科学股份有限公司 氧减少一次性套件、装置及其使用方法
CA2983295C (en) 2015-04-23 2024-02-13 New Health Sciences, Inc. Anaerobic blood storage containers
EP3297641B1 (en) 2015-05-18 2025-07-09 Hemanext Inc. Methods for the storage of whole blood, and compositions thereof
US10543304B2 (en) * 2015-11-18 2020-01-28 Gambro Lundia Ab Blood treatment apparatus with multiple axis monitor mount
PT3463466T (pt) 2016-05-27 2022-04-04 Hemanext Inc Método de armazenamento de sangue anaeróbio e inativação de patógenos
JP6821785B2 (ja) * 2016-07-22 2021-01-27 アルファ ワッサーマン インコーポレイテッドAlfa Wassermann,Inc. 超遠心分離機用の流体取扱システム及び方法
AR110862A1 (es) * 2017-02-01 2019-05-08 Bayer Healthcare Llc Reconocimiento de frecuencia acústica en vías intracorporales
US11103629B2 (en) * 2017-04-21 2021-08-31 Terumo Bct, Inc. Filler for an apheresis system
US12403240B2 (en) 2019-09-16 2025-09-02 Carefusion 303, Inc. Syringe control assembly
JP2023518823A (ja) * 2020-03-25 2023-05-08 フェンウォール、インコーポレイテッド 血液成分製造処理を自動化する設定可能なシステム
CN115418306A (zh) * 2022-07-22 2022-12-02 深圳赛桥生物创新技术有限公司 细胞处理设备

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