JP4748700B2 - ヒトミュラー管由来上皮細胞ならびにその単離方法および使用 - Google Patents

ヒトミュラー管由来上皮細胞ならびにその単離方法および使用 Download PDF

Info

Publication number
JP4748700B2
JP4748700B2 JP2001575152A JP2001575152A JP4748700B2 JP 4748700 B2 JP4748700 B2 JP 4748700B2 JP 2001575152 A JP2001575152 A JP 2001575152A JP 2001575152 A JP2001575152 A JP 2001575152A JP 4748700 B2 JP4748700 B2 JP 4748700B2
Authority
JP
Japan
Prior art keywords
cells
tube
muellerian
derived
epithelial cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2001575152A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003530100A5 (enExample
JP2003530100A (ja
Inventor
ロンハオ リ,
ジェニー パウエル メイサー,
Original Assignee
レイベン バイオテクノロジーズ,インコーポレイティド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by レイベン バイオテクノロジーズ,インコーポレイティド filed Critical レイベン バイオテクノロジーズ,インコーポレイティド
Publication of JP2003530100A publication Critical patent/JP2003530100A/ja
Publication of JP2003530100A5 publication Critical patent/JP2003530100A5/ja
Application granted granted Critical
Publication of JP4748700B2 publication Critical patent/JP4748700B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0681Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/20Transition metals
    • C12N2500/24Iron; Fe chelators; Transferrin
    • C12N2500/25Insulin-transferrin; Insulin-transferrin-selenium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70Enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00Use of cells in diagnostics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2001575152A 2000-04-07 2001-04-04 ヒトミュラー管由来上皮細胞ならびにその単離方法および使用 Expired - Fee Related JP4748700B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/545,435 2000-04-07
US09/545,435 US6416999B1 (en) 2000-04-07 2000-04-07 Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof
PCT/US2001/010998 WO2001077298A2 (en) 2000-04-07 2001-04-04 Human müllerian duct-derived epithelial cells and methods of isolation and uses thereof

Publications (3)

Publication Number Publication Date
JP2003530100A JP2003530100A (ja) 2003-10-14
JP2003530100A5 JP2003530100A5 (enExample) 2006-10-12
JP4748700B2 true JP4748700B2 (ja) 2011-08-17

Family

ID=24176236

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001575152A Expired - Fee Related JP4748700B2 (ja) 2000-04-07 2001-04-04 ヒトミュラー管由来上皮細胞ならびにその単離方法および使用

Country Status (11)

Country Link
US (2) US6416999B1 (enExample)
EP (1) EP1276850B1 (enExample)
JP (1) JP4748700B2 (enExample)
KR (1) KR100748039B1 (enExample)
CN (1) CN1423692A (enExample)
AT (1) ATE398671T1 (enExample)
AU (2) AU2001251311B2 (enExample)
CA (1) CA2404634A1 (enExample)
DE (1) DE60134469D1 (enExample)
DK (1) DK1276850T3 (enExample)
WO (1) WO2001077298A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6416999B1 (en) * 2000-04-07 2002-07-09 Raven Biotechnologies, Inc. Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof
WO2003068938A2 (en) * 2002-02-12 2003-08-21 Raven Biotechnologies, Inc Human fetal bladder-derived epithelial cells
CA2486548A1 (en) * 2002-05-30 2003-12-11 Raven Biotechnologies, Inc. Animal model for toxicology and dose prediction
EP1565489B1 (en) 2002-06-19 2010-11-17 Raven Biotechnologies, Inc. Internalizing antibodies specific for the RAAG10 cell surface target
EP1581096A4 (en) * 2002-11-13 2006-06-21 Raven Biotechnologies Inc ANTIGEN PIPA AND BINDING ANTIBODIES THEREOF
AP2949A (en) 2006-03-07 2014-07-31 Shroff Geeta Compositions comprising human embryonic stem cellsand their derivatives, methods of use, and method s of preparation
CN101855339A (zh) * 2007-01-22 2010-10-06 雷文生物技术公司 人类癌症干细胞
JP5883384B2 (ja) 2009-08-13 2016-03-15 ザ ジョンズ ホプキンス ユニバーシティー 免疫機能を調節する方法
CN102732479B (zh) * 2011-03-31 2014-08-27 北京大学 胸腺上皮前体细胞的制备方法及其专用培养基
AU2013248265B2 (en) * 2012-11-08 2018-11-01 Viacyte, Inc. Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof
CN108061804B (zh) * 2016-11-09 2020-05-12 北京大学人民医院 用于诊断子宫内膜异位症的生物标志物
CN107475369B (zh) * 2017-07-07 2021-05-04 南方医科大学 Hoxa9基因在制备治疗皮肤鳞状细胞癌药物中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1028580A (ja) * 1996-04-19 1998-02-03 Soc Prod Nestle Sa ヒト上皮大腸不死化細胞株

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6004528A (en) 1997-09-18 1999-12-21 Bergstein; Ivan Methods of cancer diagnosis and therapy targeted against the cancer stemline
US6416999B1 (en) * 2000-04-07 2002-07-09 Raven Biotechnologies, Inc. Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1028580A (ja) * 1996-04-19 1998-02-03 Soc Prod Nestle Sa ヒト上皮大腸不死化細胞株

Also Published As

Publication number Publication date
EP1276850A2 (en) 2003-01-22
EP1276850B1 (en) 2008-06-18
CN1423692A (zh) 2003-06-11
WO2001077298A2 (en) 2001-10-18
DE60134469D1 (de) 2008-07-31
CA2404634A1 (en) 2001-10-18
WO2001077298A3 (en) 2002-07-04
DK1276850T3 (da) 2008-10-13
KR100748039B1 (ko) 2007-08-09
KR20030032933A (ko) 2003-04-26
US20030040110A1 (en) 2003-02-27
US7125713B2 (en) 2006-10-24
AU5131101A (en) 2001-10-23
ATE398671T1 (de) 2008-07-15
US6416999B1 (en) 2002-07-09
JP2003530100A (ja) 2003-10-14
AU2001251311B2 (en) 2005-03-03

Similar Documents

Publication Publication Date Title
JP4566499B2 (ja) ヒト膵臓上皮前駆細胞ならびにその単離および使用の方法
AU2001257597A1 (en) Human pancreatic epithelial progenitor cells and methods of isolation and use thereof
JP4748700B2 (ja) ヒトミュラー管由来上皮細胞ならびにその単離方法および使用
AU2001251311A1 (en) Human Mullerian duct-derived epithelial cells and methods of isolation and uses thereof
AU2003219764B2 (en) Human fetal bladder-derived epithelial cells
JP4601237B2 (ja) ヒト卵巣中皮細胞ならびにその単離方法および使用
AU2001253343A1 (en) Human ovarian mesothelial cells and methods of isolation and uses thereof
HK1050710B (en) Human pancreatic epithelial progenitor cells and methods of isolation and use thereof

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060823

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060823

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090618

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20090916

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20091006

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20091014

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20091221

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100319

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100329

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100420

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100427

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100520

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100901

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20101228

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20110121

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110401

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110415

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20110511

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20110513

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140527

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140527

Year of fee payment: 3

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140527

Year of fee payment: 3

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

RD14 Notification of resignation of power of sub attorney

Free format text: JAPANESE INTERMEDIATE CODE: R3D14

LAPS Cancellation because of no payment of annual fees