DE60134469D1 - Humane epitheliale zellen von müllerian ductus-abstammende, verfahren zur ihrer isolierung und verwendungen davon - Google Patents

Humane epitheliale zellen von müllerian ductus-abstammende, verfahren zur ihrer isolierung und verwendungen davon

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Publication number
DE60134469D1
DE60134469D1 DE60134469T DE60134469T DE60134469D1 DE 60134469 D1 DE60134469 D1 DE 60134469D1 DE 60134469 T DE60134469 T DE 60134469T DE 60134469 T DE60134469 T DE 60134469T DE 60134469 D1 DE60134469 D1 DE 60134469D1
Authority
DE
Germany
Prior art keywords
epithelial cells
müllerian
derived epithelial
abstammende
ductus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60134469T
Other languages
English (en)
Inventor
Ronghao Li
Jennie Powell Mather
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Raven Biotechnologies Inc
Original Assignee
Raven Biotechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Raven Biotechnologies Inc filed Critical Raven Biotechnologies Inc
Application granted granted Critical
Publication of DE60134469D1 publication Critical patent/DE60134469D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0681Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/20Transition metals
    • C12N2500/24Iron; Fe chelators; Transferrin
    • C12N2500/25Insulin-transferrin; Insulin-transferrin-selenium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70Enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00Use of cells in diagnostics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60134469T 2000-04-07 2001-04-04 Humane epitheliale zellen von müllerian ductus-abstammende, verfahren zur ihrer isolierung und verwendungen davon Expired - Lifetime DE60134469D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/545,435 US6416999B1 (en) 2000-04-07 2000-04-07 Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof
PCT/US2001/010998 WO2001077298A2 (en) 2000-04-07 2001-04-04 Human müllerian duct-derived epithelial cells and methods of isolation and uses thereof

Publications (1)

Publication Number Publication Date
DE60134469D1 true DE60134469D1 (de) 2008-07-31

Family

ID=24176236

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60134469T Expired - Lifetime DE60134469D1 (de) 2000-04-07 2001-04-04 Humane epitheliale zellen von müllerian ductus-abstammende, verfahren zur ihrer isolierung und verwendungen davon

Country Status (11)

Country Link
US (2) US6416999B1 (de)
EP (1) EP1276850B1 (de)
JP (1) JP4748700B2 (de)
KR (1) KR100748039B1 (de)
CN (1) CN1423692A (de)
AT (1) ATE398671T1 (de)
AU (2) AU2001251311B2 (de)
CA (1) CA2404634A1 (de)
DE (1) DE60134469D1 (de)
DK (1) DK1276850T3 (de)
WO (1) WO2001077298A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6416999B1 (en) * 2000-04-07 2002-07-09 Raven Biotechnologies, Inc. Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof
JP4481652B2 (ja) * 2002-02-12 2010-06-16 レイベン バイオテクノロジーズ,インコーポレイティド ヒト胎児膀胱由来上皮細胞
CN1655671A (zh) * 2002-05-30 2005-08-17 雷文生物技术公司 毒理学和剂量预测的动物模型
EP1565489B1 (de) 2002-06-19 2010-11-17 Raven Biotechnologies, Inc. Internalisierende Antikörper spezifisch für das RAAG10 Zelloberflächenziel
EP1581096A4 (de) * 2002-11-13 2006-06-21 Raven Biotechnologies Inc Antigen-pipa und daran bindende antikörper
CA2644922C (en) 2006-03-07 2019-07-23 Geeta Shroff Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation
US8309354B2 (en) * 2007-01-22 2012-11-13 Macrogenics West, Inc. Human cancer stem cells
EP3381937A3 (de) 2009-08-13 2018-10-31 The Johns Hopkins University Verfahren zur modulierung der immunfunktion
CN102732479B (zh) * 2011-03-31 2014-08-27 北京大学 胸腺上皮前体细胞的制备方法及其专用培养基
AU2013248265B2 (en) * 2012-11-08 2018-11-01 Viacyte, Inc. Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof
CN108061804B (zh) * 2016-11-09 2020-05-12 北京大学人民医院 用于诊断子宫内膜异位症的生物标志物
CN107475369B (zh) * 2017-07-07 2021-05-04 南方医科大学 Hoxa9基因在制备治疗皮肤鳞状细胞癌药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69623109T2 (de) * 1996-04-19 2002-12-12 Nestle Sa Menschliche immortalisierte Colon-Epithelialzellen
US6004528A (en) 1997-09-18 1999-12-21 Bergstein; Ivan Methods of cancer diagnosis and therapy targeted against the cancer stemline
US6416999B1 (en) * 2000-04-07 2002-07-09 Raven Biotechnologies, Inc. Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof

Also Published As

Publication number Publication date
CN1423692A (zh) 2003-06-11
WO2001077298A3 (en) 2002-07-04
KR20030032933A (ko) 2003-04-26
US20030040110A1 (en) 2003-02-27
EP1276850A2 (de) 2003-01-22
DK1276850T3 (da) 2008-10-13
JP4748700B2 (ja) 2011-08-17
AU2001251311B2 (en) 2005-03-03
US6416999B1 (en) 2002-07-09
US7125713B2 (en) 2006-10-24
KR100748039B1 (ko) 2007-08-09
EP1276850B1 (de) 2008-06-18
ATE398671T1 (de) 2008-07-15
JP2003530100A (ja) 2003-10-14
CA2404634A1 (en) 2001-10-18
AU5131101A (en) 2001-10-23
WO2001077298A2 (en) 2001-10-18

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