JP4733349B2 - 両性イオン多糖の過剰発現の方法 - Google Patents

両性イオン多糖の過剰発現の方法 Download PDF

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Publication number
JP4733349B2
JP4733349B2 JP2003575917A JP2003575917A JP4733349B2 JP 4733349 B2 JP4733349 B2 JP 4733349B2 JP 2003575917 A JP2003575917 A JP 2003575917A JP 2003575917 A JP2003575917 A JP 2003575917A JP 4733349 B2 JP4733349 B2 JP 4733349B2
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Prior art keywords
polypeptide
seq
amino acid
nucleotide sequence
res02
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Expired - Fee Related
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JP2003575917A
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English (en)
Japanese (ja)
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JP2005519617A5 (enExample
JP2005519617A (ja
Inventor
ローリー イー． コムストック，
カトジャ ジー． ウェイナット，
マイケル ジェイ． コイネ，
デニス エル． カスパー，
アーサー オー． ツィアナボス，
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Brigham and Womens Hospital Inc
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Brigham and Womens Hospital Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
JP2003575917A 2002-03-13 2003-03-13 両性イオン多糖の過剰発現の方法 Expired - Fee Related JP4733349B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36416802P 2002-03-13 2002-03-13
US60/364,168 2002-03-13
PCT/US2003/007775 WO2003077863A2 (en) 2002-03-13 2003-03-13 Method for overexpression of zwitterionic polysaccharides

Publications (3)

Publication Number Publication Date
JP2005519617A JP2005519617A (ja) 2005-07-07
JP2005519617A5 JP2005519617A5 (enExample) 2006-04-20
JP4733349B2 true JP4733349B2 (ja) 2011-07-27

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ID=28041884

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JP2003575917A Expired - Fee Related JP4733349B2 (ja) 2002-03-13 2003-03-13 両性イオン多糖の過剰発現の方法

Country Status (7)

Country Link
US (4) US7166455B2 (enExample)
EP (1) EP1483384B1 (enExample)
JP (1) JP4733349B2 (enExample)
AT (1) ATE541036T1 (enExample)
AU (2) AU2003218144B2 (enExample)
CA (1) CA2479246C (enExample)
WO (1) WO2003077863A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
AU2003218144B2 (en) * 2002-03-13 2008-08-14 The Brigham And Women's Hospital, Inc. Method for overexpression of zwitterionic polysaccharides
EP1638581A2 (en) * 2003-03-31 2006-03-29 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy
CN102276732B (zh) 2003-11-28 2016-01-20 伊士曼化工公司 纤维素共聚体和氧化方法
WO2007092451A2 (en) * 2006-02-06 2007-08-16 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
US20110002965A1 (en) * 2007-11-09 2011-01-06 Round June L Immunomodulating compounds and related compositions and methods
US20090124573A1 (en) 2007-11-09 2009-05-14 Sarkis Mazmanian Immunomodulating compounds and related compositions and methods
US8580278B2 (en) 2009-06-03 2013-11-12 Trustees Of Dartmouth College Nutraceutical composition and methods for preventing or treating multiple sclerosis
US20100311686A1 (en) * 2009-06-03 2010-12-09 Kasper Lloyd H Nutraceutical composition and methods for preventing or treating multiple sclerosis
JP6027961B2 (ja) 2010-04-07 2016-11-16 シェン, ユエSHEN, Yue 粘膜へ化合物を送るための媒体、それに関連する組成物、方法、及びシステム
WO2011146910A1 (en) 2010-05-20 2011-11-24 Round June L Antigen specific tregs and related compositions, methods and systems
US9539281B2 (en) 2011-07-12 2017-01-10 The Brigham And Women's Hospital, Inc. Lipid-containing PSA compositions, methods of isolation and methods of use thereof
EP2764090B1 (en) * 2011-10-03 2017-12-13 California Institute of Technology Generation of psa-only producing mutant strain
EP2994161B1 (en) 2013-05-10 2020-10-28 California Institute of Technology Probiotic prevention and treatment of colon cancer
WO2016201342A1 (en) 2015-06-10 2016-12-15 California Institute Of Technology Sepsis treatment and related compositions methods and systems
CN113637040A (zh) * 2015-08-19 2021-11-12 哈佛学院院长及董事 脂化psa组合物和方法
CA3030974A1 (en) 2016-07-15 2018-01-18 President And Fellows Of Harvard College Glycolipid compositions and methods of use

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS618945A (ja) 1984-06-25 1986-01-16 Nec Corp 半導体集積回路装置
DE3750125T2 (de) * 1986-03-26 1994-10-27 Genexpress Aps Biologische eindämmung.
US4952524A (en) 1989-05-05 1990-08-28 At&T Bell Laboratories Semiconductor device manufacture including trench formation
KR940006696B1 (ko) 1991-01-16 1994-07-25 금성일렉트론 주식회사 반도체 소자의 격리막 형성방법
US5350941A (en) 1992-09-23 1994-09-27 Texas Instruments Incorporated Trench isolation structure having a trench formed in a LOCOS structure and a channel stop region on the sidewalls of the trench
US5433794A (en) 1992-12-10 1995-07-18 Micron Technology, Inc. Spacers used to form isolation trenches with improved corners
JPH07326664A (ja) 1994-05-31 1995-12-12 Fuji Electric Co Ltd ウエハの誘電体分離溝の充填方法
US5700787A (en) * 1994-09-02 1997-12-23 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
US5679654A (en) * 1994-09-02 1997-10-21 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
US5851808A (en) * 1997-02-28 1998-12-22 Baylor College Of Medicine Rapid subcloning using site-specific recombination
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
AU2003218144B2 (en) 2002-03-13 2008-08-14 The Brigham And Women's Hospital, Inc. Method for overexpression of zwitterionic polysaccharides
EP1638581A2 (en) 2003-03-31 2006-03-29 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy

Also Published As

Publication number Publication date
AU2003218144B2 (en) 2008-08-14
US20080057565A1 (en) 2008-03-06
EP1483384A2 (en) 2004-12-08
AU2003218144A1 (en) 2003-09-29
CA2479246C (en) 2017-05-09
AU2008243143B2 (en) 2012-10-04
EP1483384B1 (en) 2012-01-11
US20030219413A1 (en) 2003-11-27
ATE541036T1 (de) 2012-01-15
JP2005519617A (ja) 2005-07-07
US20070154991A1 (en) 2007-07-05
CA2479246A1 (en) 2003-09-25
EP1483384A4 (en) 2006-11-02
WO2003077863A3 (en) 2004-07-22
US7678558B2 (en) 2010-03-16
WO2003077863A2 (en) 2003-09-25
US20070020730A1 (en) 2007-01-25
US7803602B2 (en) 2010-09-28
US7166455B2 (en) 2007-01-23
AU2008243143A1 (en) 2008-11-27

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