ATE541036T1 - Verfahren zur überexpression zwitterionischer polysaccharide - Google Patents
Verfahren zur überexpression zwitterionischer polysaccharideInfo
- Publication number
- ATE541036T1 ATE541036T1 AT03714135T AT03714135T ATE541036T1 AT E541036 T1 ATE541036 T1 AT E541036T1 AT 03714135 T AT03714135 T AT 03714135T AT 03714135 T AT03714135 T AT 03714135T AT E541036 T1 ATE541036 T1 AT E541036T1
- Authority
- AT
- Austria
- Prior art keywords
- overexpressing
- compositions
- directed
- capsular
- polysaccharides
- Prior art date
Links
- 150000004676 glycans Chemical class 0.000 title abstract 7
- 229920001282 polysaccharide Polymers 0.000 title abstract 7
- 239000005017 polysaccharide Substances 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 abstract 3
- 241000421809 Brisaster fragilis Species 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36416802P | 2002-03-13 | 2002-03-13 | |
| PCT/US2003/007775 WO2003077863A2 (en) | 2002-03-13 | 2003-03-13 | Method for overexpression of zwitterionic polysaccharides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE541036T1 true ATE541036T1 (de) | 2012-01-15 |
Family
ID=28041884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03714135T ATE541036T1 (de) | 2002-03-13 | 2003-03-13 | Verfahren zur überexpression zwitterionischer polysaccharide |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US7166455B2 (enExample) |
| EP (1) | EP1483384B1 (enExample) |
| JP (1) | JP4733349B2 (enExample) |
| AT (1) | ATE541036T1 (enExample) |
| AU (2) | AU2003218144B2 (enExample) |
| CA (1) | CA2479246C (enExample) |
| WO (1) | WO2003077863A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7083777B1 (en) * | 1999-04-02 | 2006-08-01 | The Brigham And Women's Hospital, Inc. | Immunomodulating polymers |
| SV2003000753A (es) | 2000-12-05 | 2003-06-16 | Brigham & Womens Hospital | Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico |
| AU2003218144B2 (en) * | 2002-03-13 | 2008-08-14 | The Brigham And Women's Hospital, Inc. | Method for overexpression of zwitterionic polysaccharides |
| EP1638581A2 (en) * | 2003-03-31 | 2006-03-29 | The Brigham And Women's Hospital, Inc. | Zwitterionic immunomodulators for the treatment of asthma and allergy |
| CN102276732B (zh) | 2003-11-28 | 2016-01-20 | 伊士曼化工公司 | 纤维素共聚体和氧化方法 |
| WO2007092451A2 (en) * | 2006-02-06 | 2007-08-16 | The Brigham And Women's Hospital, Inc. | Zwitterionic polysaccharides for promotion of immune system maturation and health |
| US20110002965A1 (en) * | 2007-11-09 | 2011-01-06 | Round June L | Immunomodulating compounds and related compositions and methods |
| US20090124573A1 (en) | 2007-11-09 | 2009-05-14 | Sarkis Mazmanian | Immunomodulating compounds and related compositions and methods |
| US8580278B2 (en) | 2009-06-03 | 2013-11-12 | Trustees Of Dartmouth College | Nutraceutical composition and methods for preventing or treating multiple sclerosis |
| US20100311686A1 (en) * | 2009-06-03 | 2010-12-09 | Kasper Lloyd H | Nutraceutical composition and methods for preventing or treating multiple sclerosis |
| JP6027961B2 (ja) | 2010-04-07 | 2016-11-16 | シェン, ユエSHEN, Yue | 粘膜へ化合物を送るための媒体、それに関連する組成物、方法、及びシステム |
| WO2011146910A1 (en) | 2010-05-20 | 2011-11-24 | Round June L | Antigen specific tregs and related compositions, methods and systems |
| US9539281B2 (en) | 2011-07-12 | 2017-01-10 | The Brigham And Women's Hospital, Inc. | Lipid-containing PSA compositions, methods of isolation and methods of use thereof |
| EP2764090B1 (en) * | 2011-10-03 | 2017-12-13 | California Institute of Technology | Generation of psa-only producing mutant strain |
| EP2994161B1 (en) | 2013-05-10 | 2020-10-28 | California Institute of Technology | Probiotic prevention and treatment of colon cancer |
| WO2016201342A1 (en) | 2015-06-10 | 2016-12-15 | California Institute Of Technology | Sepsis treatment and related compositions methods and systems |
| CN113637040A (zh) * | 2015-08-19 | 2021-11-12 | 哈佛学院院长及董事 | 脂化psa组合物和方法 |
| CA3030974A1 (en) | 2016-07-15 | 2018-01-18 | President And Fellows Of Harvard College | Glycolipid compositions and methods of use |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS618945A (ja) | 1984-06-25 | 1986-01-16 | Nec Corp | 半導体集積回路装置 |
| DE3750125T2 (de) * | 1986-03-26 | 1994-10-27 | Genexpress Aps | Biologische eindämmung. |
| US4952524A (en) | 1989-05-05 | 1990-08-28 | At&T Bell Laboratories | Semiconductor device manufacture including trench formation |
| KR940006696B1 (ko) | 1991-01-16 | 1994-07-25 | 금성일렉트론 주식회사 | 반도체 소자의 격리막 형성방법 |
| US5350941A (en) | 1992-09-23 | 1994-09-27 | Texas Instruments Incorporated | Trench isolation structure having a trench formed in a LOCOS structure and a channel stop region on the sidewalls of the trench |
| US5433794A (en) | 1992-12-10 | 1995-07-18 | Micron Technology, Inc. | Spacers used to form isolation trenches with improved corners |
| JPH07326664A (ja) | 1994-05-31 | 1995-12-12 | Fuji Electric Co Ltd | ウエハの誘電体分離溝の充填方法 |
| US5700787A (en) * | 1994-09-02 | 1997-12-23 | Brigham & Women's Hospital, Inc. | Capsular polysaccharide immunomodulator |
| US5679654A (en) * | 1994-09-02 | 1997-10-21 | Brigham & Women's Hospital, Inc. | Capsular polysaccharide immunomodulator |
| US5851808A (en) * | 1997-02-28 | 1998-12-22 | Baylor College Of Medicine | Rapid subcloning using site-specific recombination |
| US7083777B1 (en) * | 1999-04-02 | 2006-08-01 | The Brigham And Women's Hospital, Inc. | Immunomodulating polymers |
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| SV2003000753A (es) | 2000-12-05 | 2003-06-16 | Brigham & Womens Hospital | Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico |
| AU2003218144B2 (en) | 2002-03-13 | 2008-08-14 | The Brigham And Women's Hospital, Inc. | Method for overexpression of zwitterionic polysaccharides |
| EP1638581A2 (en) | 2003-03-31 | 2006-03-29 | The Brigham And Women's Hospital, Inc. | Zwitterionic immunomodulators for the treatment of asthma and allergy |
-
2003
- 2003-03-13 AU AU2003218144A patent/AU2003218144B2/en not_active Ceased
- 2003-03-13 AT AT03714135T patent/ATE541036T1/de active
- 2003-03-13 WO PCT/US2003/007775 patent/WO2003077863A2/en not_active Ceased
- 2003-03-13 US US10/388,390 patent/US7166455B2/en not_active Expired - Lifetime
- 2003-03-13 CA CA2479246A patent/CA2479246C/en not_active Expired - Fee Related
- 2003-03-13 EP EP03714135A patent/EP1483384B1/en not_active Expired - Lifetime
- 2003-03-13 JP JP2003575917A patent/JP4733349B2/ja not_active Expired - Fee Related
-
2006
- 2006-09-26 US US11/527,194 patent/US20070020730A1/en not_active Abandoned
-
2007
- 2007-01-17 US US11/654,246 patent/US7678558B2/en not_active Expired - Fee Related
- 2007-08-20 US US11/894,552 patent/US7803602B2/en not_active Expired - Fee Related
-
2008
- 2008-11-06 AU AU2008243143A patent/AU2008243143B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003218144B2 (en) | 2008-08-14 |
| US20080057565A1 (en) | 2008-03-06 |
| EP1483384A2 (en) | 2004-12-08 |
| JP4733349B2 (ja) | 2011-07-27 |
| AU2003218144A1 (en) | 2003-09-29 |
| CA2479246C (en) | 2017-05-09 |
| AU2008243143B2 (en) | 2012-10-04 |
| EP1483384B1 (en) | 2012-01-11 |
| US20030219413A1 (en) | 2003-11-27 |
| JP2005519617A (ja) | 2005-07-07 |
| US20070154991A1 (en) | 2007-07-05 |
| CA2479246A1 (en) | 2003-09-25 |
| EP1483384A4 (en) | 2006-11-02 |
| WO2003077863A3 (en) | 2004-07-22 |
| US7678558B2 (en) | 2010-03-16 |
| WO2003077863A2 (en) | 2003-09-25 |
| US20070020730A1 (en) | 2007-01-25 |
| US7803602B2 (en) | 2010-09-28 |
| US7166455B2 (en) | 2007-01-23 |
| AU2008243143A1 (en) | 2008-11-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE541036T1 (de) | Verfahren zur überexpression zwitterionischer polysaccharide | |
| WO2005059093A3 (de) | P ef-tu-expressionseinheiten | |
| WO2005016962A3 (en) | Compositions and methods for the treatment of immune related diseases | |
| MX2015012865A (es) | Metodos para purificacion de arn mensajero. | |
| ATE443757T1 (de) | L-aminosäure produzierender mikroorganismus und verfahren zur l-aminosäureproduktion | |
| ATE322252T1 (de) | Verfahren zur herstellung und sammlung von kristallinen partikeln | |
| ATE306252T1 (de) | Verfahren zur herstellung kristalliner partikel zur inhalation | |
| WO2005063997A3 (en) | Maize metallothionein promoter | |
| MXPA05012362A (es) | Yodopirazolilcarboxanilidas. | |
| ATE345385T1 (de) | Für gefässgewebe spezifische promotoren | |
| DE602004024686D1 (de) | Cephalosporin-c-acylase-mutante und verfahren zur herstellung von 7-aca damit | |
| ATE302844T1 (de) | Verfahren zur aufreinigung eines enzyms und hiernach hergestelltes, aufgereinigtes enzym sowie verwendung des enzyms | |
| DE60332107D1 (de) | Saatspezifische usp-promotoren zur expression von genen in pflanzen | |
| NO20051292L (no) | Fremgangsmate for separasjon av intermediater som kan anvendes for fremstillingen av escitalopram. | |
| EP1668125A4 (en) | MODIFIED ENZYMES, PROCESSES FOR PRODUCING MODIFIED ENZYMES AND USES THEREOF | |
| DE60225312D1 (de) | Samenspezifische 7s-alpha-promoter zur expression von genen in pflanzen | |
| WO2003024393A3 (en) | Autologous t-cell vaccines materials and method | |
| DE60125528D1 (de) | Isolierung und charakterisierung des csa-operons (etec-cs4 pili) und verfahren zu dessen anwendung | |
| ATE491798T1 (de) | Perikarp-bevorzugtes regulationselement | |
| MY140061A (en) | Improved method for the production of ramipril | |
| WO2005003151A3 (en) | Method and apparatus for continuous large-scale radiolabeling of proteins | |
| DE50305958D1 (de) | Verfahren zum nachweis von mikroorganismen mittels in situ-hybridisierung und durchflusszytometrie | |
| WO2004043397A3 (en) | Compositions and methods for the treatment of rheumatoid arthritis | |
| WO2003064597A3 (en) | Aggrecanase molecules | |
| TW200612833A (en) | Genetically purified gellan gum |