JP4709383B2 - Ｕｃｐ４ - Google Patents

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Publication number
JP4709383B2
JP4709383B2 JP2000574252A JP2000574252A JP4709383B2 JP 4709383 B2 JP4709383 B2 JP 4709383B2 JP 2000574252 A JP2000574252 A JP 2000574252A JP 2000574252 A JP2000574252 A JP 2000574252A JP 4709383 B2 JP4709383 B2 JP 4709383B2
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JP
Japan
Prior art keywords
ucp4
polypeptide
dna
sequence
molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2000574252A
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English (en)
Japanese (ja)
Other versions
JP2002526075A5 (enExample
JP2002526075A (ja
Inventor
アダムズ，ション
パン，ジェームズ
ジョン，アラン
Original Assignee
ジェネンテック， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ジェネンテック， インコーポレイテッド filed Critical ジェネンテック， インコーポレイテッド
Publication of JP2002526075A publication Critical patent/JP2002526075A/ja
Publication of JP2002526075A5 publication Critical patent/JP2002526075A5/ja
Application granted granted Critical
Publication of JP4709383B2 publication Critical patent/JP4709383B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2000574252A 1998-09-22 1999-09-15 Ｕｃｐ４ Expired - Lifetime JP4709383B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US10127998P 1998-09-22 1998-09-22
US60/101,279 1998-09-22
US11422398P 1998-12-30 1998-12-30
US60/114,223 1998-12-30
US12967499P 1999-04-16 1999-04-16
US60/129,674 1999-04-16
PCT/US1999/021194 WO2000017353A1 (en) 1998-09-22 1999-09-15 Ucp4

Publications (3)

Publication Number Publication Date
JP2002526075A JP2002526075A (ja) 2002-08-20
JP2002526075A5 JP2002526075A5 (enExample) 2009-12-03
JP4709383B2 true JP4709383B2 (ja) 2011-06-22

Family

ID=27379161

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000574252A Expired - Lifetime JP4709383B2 (ja) 1998-09-22 1999-09-15 Ｕｃｐ４

Country Status (10)

Country Link
US (3) US8067229B2 (enExample)
EP (1) EP1115863B1 (enExample)
JP (1) JP4709383B2 (enExample)
AU (1) AU6041399A (enExample)
CA (1) CA2344467C (enExample)
DE (1) DE69937644T2 (enExample)
DK (1) DK1115863T3 (enExample)
ES (1) ES2297947T3 (enExample)
PT (1) PT1115863E (enExample)
WO (1) WO2000017353A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6670138B2 (en) 2000-11-01 2003-12-30 Agy Therapeutics, Inc. Method of diagnosing ischemic stroke via UCP-2 detection

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775662A (en) 1983-03-07 1988-10-04 Smithkline Beckman Corporation Leukotriene antagonists
US5010010A (en) 1986-10-22 1991-04-23 Selmer-Sande, A.S. Production of human parathyroid hormone from microorganisms
IL87737A (en) 1987-09-11 1993-08-18 Genentech Inc Method for culturing polypeptide factor dependent vertebrate recombinant cells
US5663304A (en) 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
US5407810A (en) 1993-08-20 1995-04-18 Genentech, Inc. Aqueous multiple-phase isolation of polypeptide
AU5632296A (en) * 1995-04-27 1996-11-18 Abgenix, Inc. Human antibodies derived from immunized xenomice
AU2809797A (en) * 1997-01-15 1998-08-07 Centre National De La Recherche Scientifique Centre De Recherche Sur L'endocrinologie Moleculaire Et Le Developpement Respiration uncoupling protein
US7001742B1 (en) * 1997-05-20 2006-02-21 Merck & Co., Inc. Human uncoupling protein 3
EP1012155A4 (en) 1997-05-20 2002-11-04 Merck & Co Inc HUMAN 'UNCOUPLING' PROTEIN 3
NZ531664A (en) * 1998-09-01 2005-07-29 Genentech Inc Pro1317 polypeptides and sequences thereof with homology to the semaphorin B glycoprotein family
US7026455B2 (en) 1998-09-01 2006-04-11 Genentech, Inc. Anti-pro 1343 antibodies

Also Published As

Publication number Publication date
DE69937644D1 (en) 2008-01-10
DK1115863T3 (da) 2008-03-31
US8313927B2 (en) 2012-11-20
WO2000017353A1 (en) 2000-03-30
US20120041176A1 (en) 2012-02-16
US20060068439A1 (en) 2006-03-30
US8648174B2 (en) 2014-02-11
PT1115863E (pt) 2008-03-07
EP1115863A1 (en) 2001-07-18
CA2344467A1 (en) 2000-03-30
ES2297947T3 (es) 2008-05-01
EP1115863B1 (en) 2007-11-28
DE69937644T2 (de) 2008-10-30
AU6041399A (en) 2000-04-10
US20130066052A1 (en) 2013-03-14
US8067229B2 (en) 2011-11-29
JP2002526075A (ja) 2002-08-20
CA2344467C (en) 2011-01-25

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