JP4688308B2 - 感光性ポリマ部材を有する溶融シリカキャピラリ - Google Patents
感光性ポリマ部材を有する溶融シリカキャピラリ Download PDFInfo
- Publication number
- JP4688308B2 JP4688308B2 JP2001039510A JP2001039510A JP4688308B2 JP 4688308 B2 JP4688308 B2 JP 4688308B2 JP 2001039510 A JP2001039510 A JP 2001039510A JP 2001039510 A JP2001039510 A JP 2001039510A JP 4688308 B2 JP4688308 B2 JP 4688308B2
- Authority
- JP
- Japan
- Prior art keywords
- separation
- separation column
- frit
- photosensitive polymer
- channel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44747—Composition of gel or of carrier mixture
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6004—Construction of the column end pieces
- G01N30/603—Construction of the column end pieces retaining the stationary phase, e.g. Frits
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N2030/285—Control of physical parameters of the fluid carrier electrically driven carrier
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/56—Packing methods or coating methods
- G01N2030/562—Packing methods or coating methods packing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6004—Construction of the column end pieces
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Dispersion Chemistry (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50770700A | 2000-02-18 | 2000-02-18 | |
| US09/507707 | 2000-02-18 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001264306A JP2001264306A (ja) | 2001-09-26 |
| JP2001264306A5 JP2001264306A5 (enExample) | 2008-03-27 |
| JP4688308B2 true JP4688308B2 (ja) | 2011-05-25 |
Family
ID=24019792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001039510A Expired - Lifetime JP4688308B2 (ja) | 2000-02-18 | 2001-02-16 | 感光性ポリマ部材を有する溶融シリカキャピラリ |
Country Status (3)
| Country | Link |
|---|---|
| US (2) | US20020079257A1 (enExample) |
| EP (1) | EP1126275A3 (enExample) |
| JP (1) | JP4688308B2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6875348B2 (en) * | 2000-02-18 | 2005-04-05 | The Board Of Trustees Of The Leland Stanford Junior University | Separation column having a photopolymerized sol-gel component and associated methods |
| EP1126275A3 (en) | 2000-02-18 | 2002-12-18 | The Board Of Trustees Of The Leland Stanford Junior University | Fused-silicia capillaries with photopolymer components |
| US7261812B1 (en) * | 2002-02-13 | 2007-08-28 | Nanostream, Inc. | Multi-column separation devices and methods |
| AU2003238802A1 (en) * | 2002-05-29 | 2003-12-19 | University Of Florida | Method and apparatus for detecting and monitoring peptides, and peptides identified therewith |
| US6749749B2 (en) * | 2002-06-26 | 2004-06-15 | Isco, Inc. | Separation system, components of a separation system and methods of making and using them |
| US7473367B2 (en) * | 2002-06-26 | 2009-01-06 | Dionex Corporation | Monolithic column |
| US20050061745A1 (en) * | 2002-06-26 | 2005-03-24 | Teledyne Isco, Inc. | Separation system, components of a separation system and methods of making and using them |
| US20050127002A1 (en) * | 2003-12-12 | 2005-06-16 | Zare Richard N. | Immobilized-enzyme microreactor devices for characterization of biomolecular analytes and associated methods |
| EP2164589B1 (en) * | 2007-06-01 | 2015-03-04 | Dana-Farber Cancer Institute, Inc. | Chromatographic columns with integrated electrospray emitters |
| KR101012189B1 (ko) | 2009-01-29 | 2011-02-08 | 인하대학교 산학협력단 | 실리카모세관 컬럼의 제조방법 및 상기 제조방법으로 얻어진 실리카모세관 컬럼 |
| JP5320416B2 (ja) * | 2011-01-26 | 2013-10-23 | 株式会社日立ハイテクノロジーズ | 電気泳動装置,キャピラリアレイ、及びキャピラリユニット |
| CN102967675B (zh) * | 2012-12-18 | 2013-10-16 | 中国烟草总公司郑州烟草研究院 | 一种适用于烟碱及其代谢物分离的毛细管电色谱测定方法 |
| US9129785B2 (en) | 2013-08-01 | 2015-09-08 | The Board Of Trustees Of The Leland Stanford Junior University | Metal organic polymer matrices and systems for chemical and biochemical mass spectrometry and methods of use thereof |
| WO2016090064A1 (en) * | 2014-12-05 | 2016-06-09 | Advanced Electrophoresis Solutions Ltd | Apparatus and method for separating molecules |
Family Cites Families (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3503711A (en) * | 1965-12-23 | 1970-03-31 | Gen Electric | Ammonia detection apparatus and method |
| US3503712A (en) | 1966-05-18 | 1970-03-31 | Research Corp | Apparatus for effecting interactions of fluids at extended solid surfaces |
| US3568840A (en) | 1967-12-30 | 1971-03-09 | Mitsubishi Chem Ind | Packing materials for gel permeation chromatography |
| US3757490A (en) | 1971-06-07 | 1973-09-11 | Ja Ma | Chromatographic adsorbents |
| US3808125A (en) | 1972-08-25 | 1974-04-30 | Phillips Petroleum Co | Chromatographic apparatus |
| US3878092A (en) | 1973-03-12 | 1975-04-15 | Phillips Petroleum Co | Chromatographic colums |
| US4293415A (en) * | 1979-04-27 | 1981-10-06 | Hewlett-Packard Company | Silica chromatographic column |
| US4323439A (en) | 1979-12-31 | 1982-04-06 | The Regents Of The University Of California | Method and apparatus for dynamic equilibrium electrophoresis |
| US4790919A (en) * | 1984-06-28 | 1988-12-13 | E. I. Du Pont De Nemours And Company | Process for preparation of electrophoresis gel material |
| US4617102A (en) | 1985-03-21 | 1986-10-14 | Lifecodes Corp. | Process and apparatus for purifying and concentrating DNA from crude mixtures containing DNA |
| US4675300A (en) | 1985-09-18 | 1987-06-23 | The Board Of Trustees Of The Leland Stanford Junior University | Laser-excitation fluorescence detection electrokinetic separation |
| US4793920A (en) | 1985-12-11 | 1988-12-27 | Lee Scientific, Inc. | Chromatography columns with cast porous plugs and methods of fabricating same |
| US5116495A (en) | 1987-09-11 | 1992-05-26 | Ottosensors Corporation | Capillary chromatography device |
| US5202010A (en) | 1987-11-25 | 1993-04-13 | Princeton Biochemicals, Inc. | Automated capillary electrophoresis apparatus |
| IL93134A (en) | 1990-01-23 | 1997-11-20 | Yissum Res Dev Co | Doped sol-gel glasses for obtaining chemical interactions |
| US5308495A (en) | 1990-01-23 | 1994-05-03 | Yissum, Research Development Company Of The Hebrew University Of Jerusalem | Chromatography processes using doped sol gel glasses as chromatographic media |
| US5200150A (en) * | 1990-06-14 | 1993-04-06 | Hewlett-Packard Company | Preparation of gel-filled separation columns |
| US5085756A (en) | 1990-08-21 | 1992-02-04 | Hewlett-Packard Company | Column separation system for electrophoresis with sample pretreatment |
| US5135627A (en) * | 1990-10-15 | 1992-08-04 | Soane Technologies, Inc. | Mosaic microcolumns, slabs, and separation media for electrophoresis and chromatography |
| US5340452A (en) | 1991-02-01 | 1994-08-23 | Beckman Instruments, Inc. | On-column preconcentration of samples in capillary electrophoresis |
| US5453382A (en) * | 1991-08-05 | 1995-09-26 | Indiana University Foundation | Electrochromatographic preconcentration method |
| US5116471A (en) | 1991-10-04 | 1992-05-26 | Varian Associates, Inc. | System and method for improving sample concentration in capillary electrophoresis |
| JP3168006B2 (ja) | 1991-10-21 | 2001-05-21 | コーネル・リサーチ・フアウンデーシヨン・インコーポレーテツド | マクロ細孔ポリマー媒体が備わっているカラム |
| US5552994A (en) | 1992-09-23 | 1996-09-03 | Onkor, Ltd. | System for printing social expression cards in response to electronically transmitted orders |
| US5316680A (en) | 1992-10-21 | 1994-05-31 | Cornell Research Foundation, Inc. | Multimodal chromatographic separation media and process for using same |
| US5505831A (en) | 1993-01-26 | 1996-04-09 | Bio-Rad Laboratories, Inc. | Concentration of biological samples on a microliter scale and analysis by capillary electrophoresis |
| US5624875A (en) | 1993-07-19 | 1997-04-29 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Inorganic porous material and process for making same |
| DE4344308A1 (de) | 1993-12-23 | 1995-06-29 | Consortium Elektrochem Ind | Polymerisierbare flüssigkristalline Siloxane |
| US5423966A (en) | 1994-01-25 | 1995-06-13 | Perkin-Elmer Corporation | On line ion contaminant removal apparatus and method for capillary electrophoresis |
| US5653875A (en) | 1994-02-04 | 1997-08-05 | Supelco, Inc. | Nucleophilic bodies bonded to siloxane and use thereof for separations from sample matrices |
| SE9402091D0 (sv) | 1994-06-14 | 1994-06-14 | Pharmacia Biotech Ab | Kromatografikolonn |
| US5728457A (en) | 1994-09-30 | 1998-03-17 | Cornell Research Foundation, Inc. | Porous polymeric material with gradients |
| JPH09511838A (ja) | 1995-03-03 | 1997-11-25 | オールテック アソシエイツ インコーポレイテッド | クロマトグラフィー物質を電気化学的に改良するための装置/方法 |
| US5800692A (en) | 1995-04-17 | 1998-09-01 | Mayo Foundation For Medical Education And Research | Preseparation processor for use in capillary electrophoresis |
| US5722875A (en) * | 1995-05-30 | 1998-03-03 | Tokyo Electron Limited | Method and apparatus for polishing |
| US5637135A (en) | 1995-06-26 | 1997-06-10 | Capillary Technology Corporation | Chromatographic stationary phases and adsorbents from hybrid organic-inorganic sol-gels |
| WO1997017384A1 (en) * | 1995-11-08 | 1997-05-15 | Kirkpatrick Francis H | Methods and reagents for gel electrophoresis |
| EP0779512B1 (en) | 1995-12-14 | 2001-10-31 | Hewlett-Packard Company, A Delaware Corporation | Column for capillary chromatographic separations |
| US5938919A (en) * | 1995-12-22 | 1999-08-17 | Phenomenex | Fused silica capillary columns protected by flexible shielding |
| US5667674A (en) | 1996-01-11 | 1997-09-16 | Minnesota Mining And Manufacturing Company | Adsorption medium and method of preparing same |
| US5728296A (en) | 1996-03-20 | 1998-03-17 | Bio-Rad Laboratories, Inc. | Selective recognition of solutes in chromatographic media by artificially created affinity |
| EP0809108B1 (en) | 1996-05-20 | 2003-09-24 | Agilent Technologies, Inc. (a Delaware corporation) | Column for capillary chromatographic separations and method of manufacturing same |
| US5647979A (en) | 1996-06-14 | 1997-07-15 | Bio-Rad Laboratories, Inc. | One-step preparation of separation media for reversed-phase chromatography |
| US5719322A (en) | 1996-09-20 | 1998-02-17 | Uop | Zeolitic capillary columns for gas chromatography |
| JP3911684B2 (ja) * | 1996-11-12 | 2007-05-09 | 株式会社ケムコ | 分離用カラムの製造方法 |
| WO1998029350A2 (en) | 1996-12-26 | 1998-07-09 | Merck Patent Gmbh | Inorganic porous material and process for making same |
| US6398962B1 (en) | 1997-06-18 | 2002-06-04 | Merck Kgaa | Use of monolithic sorbents for preparative chromatographic separation |
| US6136187A (en) * | 1997-12-09 | 2000-10-24 | The Board Of Trustees Of The Leland Stanford Junior University | Separation column containing porous matrix and method of packing column |
| US6562744B1 (en) | 1998-01-23 | 2003-05-13 | Merck Patent Gmbh | Process for producing inorganic porous material in a capillary |
| JPH11287791A (ja) | 1998-04-01 | 1999-10-19 | Naohiro Soga | キャピラリーカラム |
| US6210570B1 (en) | 1998-08-21 | 2001-04-03 | Agilent Technologies, Inc. | Monolithic silica column |
| US6402918B1 (en) | 1998-11-16 | 2002-06-11 | Joseph B. Schlenoff | Apparatus for capillary electrophoresis and associated method |
| US6428666B1 (en) | 1999-02-22 | 2002-08-06 | Sandia National Laboratories | Electrokinetic concentration of charged molecules |
| EP1126275A3 (en) | 2000-02-18 | 2002-12-18 | The Board Of Trustees Of The Leland Stanford Junior University | Fused-silicia capillaries with photopolymer components |
-
2001
- 2001-02-06 EP EP01301043A patent/EP1126275A3/en not_active Withdrawn
- 2001-02-16 JP JP2001039510A patent/JP4688308B2/ja not_active Expired - Lifetime
- 2001-11-13 US US10/008,482 patent/US20020079257A1/en not_active Abandoned
-
2003
- 2003-09-29 US US10/674,652 patent/US6986841B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1126275A2 (en) | 2001-08-22 |
| JP2001264306A (ja) | 2001-09-26 |
| US6986841B2 (en) | 2006-01-17 |
| EP1126275A3 (en) | 2002-12-18 |
| US20020079257A1 (en) | 2002-06-27 |
| US20040055940A1 (en) | 2004-03-25 |
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