JP4669180B2 - ルシフェラーゼ発現カセットおよび使用法 - Google Patents

ルシフェラーゼ発現カセットおよび使用法 Download PDF

Info

Publication number
JP4669180B2
JP4669180B2 JP2001522406A JP2001522406A JP4669180B2 JP 4669180 B2 JP4669180 B2 JP 4669180B2 JP 2001522406 A JP2001522406 A JP 2001522406A JP 2001522406 A JP2001522406 A JP 2001522406A JP 4669180 B2 JP4669180 B2 JP 4669180B2
Authority
JP
Japan
Prior art keywords
expression cassette
sequence
expression
gram
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2001522406A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003509029A5 (https=
JP2003509029A (ja
Inventor
ケビン ピー． フランシス，
パメラ アール． カンタグ，
デニー ジェイ． ジョー，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xenogen Corp
Original Assignee
Xenogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenogen Corp filed Critical Xenogen Corp
Publication of JP2003509029A publication Critical patent/JP2003509029A/ja
Publication of JP2003509029A5 publication Critical patent/JP2003509029A5/ja
Application granted granted Critical
Publication of JP4669180B2 publication Critical patent/JP4669180B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1051—Gene trapping, e.g. exon-, intron-, IRES-, signal sequence-trap cloning, trap vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2001522406A 1999-09-08 2000-09-07 ルシフェラーゼ発現カセットおよび使用法 Expired - Lifetime JP4669180B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15290499P 1999-09-08 1999-09-08
US60/152,904 1999-09-08
PCT/US2000/024699 WO2001018195A2 (en) 1999-09-08 2000-09-07 Luciferase expression cassettes and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010256354A Division JP5295206B2 (ja) 1999-09-08 2010-11-16 ルシフェラーゼ発現カセットおよび使用法

Publications (3)

Publication Number Publication Date
JP2003509029A JP2003509029A (ja) 2003-03-11
JP2003509029A5 JP2003509029A5 (https=) 2011-01-13
JP4669180B2 true JP4669180B2 (ja) 2011-04-13

Family

ID=22544956

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2001522406A Expired - Lifetime JP4669180B2 (ja) 1999-09-08 2000-09-07 ルシフェラーゼ発現カセットおよび使用法
JP2010256354A Expired - Fee Related JP5295206B2 (ja) 1999-09-08 2010-11-16 ルシフェラーゼ発現カセットおよび使用法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010256354A Expired - Fee Related JP5295206B2 (ja) 1999-09-08 2010-11-16 ルシフェラーゼ発現カセットおよび使用法

Country Status (8)

Country Link
EP (2) EP1728866B1 (https=)
JP (2) JP4669180B2 (https=)
AT (2) ATE448309T1 (https=)
AU (1) AU779263B2 (https=)
CA (1) CA2384496A1 (https=)
DE (2) DE60043321D1 (https=)
ES (1) ES2267561T3 (https=)
WO (1) WO2001018195A2 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7255851B2 (en) 1994-07-01 2007-08-14 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive localization of a light-emitting conjugate in a mammal
US6649143B1 (en) 1994-07-01 2003-11-18 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive localization of a light-emitting conjugate in a mammal
AU774183B2 (en) 1998-12-17 2004-06-17 Xenogen Corporation Non-invasive evaluation of physiological response in a mammal
US6610503B1 (en) 1999-03-17 2003-08-26 Xenogen Corporation Animal models for predicting sepsis mortality
US6737245B1 (en) 1999-09-08 2004-05-18 Xenogen Corporation Luciferase expression cassettes and methods of use
US6867348B1 (en) 1999-12-16 2005-03-15 Xenogen Corporation Methods and compositions for screening for angiogenesis modulating compounds
IT1311335B1 (it) 1999-12-21 2002-03-12 Otc Optical Technologies Ct S Procedimento e dispositivo per realizzare reticoli in fibra ottica.
US7056728B2 (en) 2000-07-06 2006-06-06 Xenogen Corporation Compositions and methods for use thereof in modifying the genomes of microorganisms
US6858773B2 (en) 2001-04-20 2005-02-22 Xenogen Corporation Transgenic mice comprising transcription control elements associated with mouse eosinophil peroxidase expression
CA2452876A1 (en) * 2001-07-09 2003-01-23 Anticancer, Inc. Imaging infection using fluorescent protein as a marker
EP1281772A1 (en) * 2001-07-31 2003-02-05 Aladar A. Szalay Light-emitting microorganisms and cells for tumour diagnosis/therapy
EP1281767A3 (en) * 2001-07-31 2003-05-28 Aladar A. Szalay Light emitting microorganisms and cells for diagnosis and therapy of tumors
EP1644492B1 (en) 2003-06-18 2009-01-07 Genelux Corporation Modified recombinant vaccinia viruses, uses thereof
EP2426142A3 (en) 2006-10-16 2012-06-13 Genelux Corporation Modified vaccinia virus strains for use in a diagnostic and therapeutic method
US7910087B2 (en) 2007-03-02 2011-03-22 University Of Massachusetts Luciferins
WO2015031859A1 (en) * 2013-08-29 2015-03-05 The Regents Of The University Of California Bacteria engineered for ester production
WO2020243660A1 (en) 2019-05-30 2020-12-03 490 BioTech, Inc. Lux expression in cells and methods of use
CN110295181B (zh) * 2019-06-18 2022-10-11 山东大学 一种利用生物发光报告系统鉴定抗生素种类的方法
DE102020129009A1 (de) 2020-11-04 2022-05-05 Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Körperschaft des öffentlichen Rechts Nachweis von umwelteinflüssen mittels biolumineszenz
CN113403243B (zh) * 2021-06-16 2022-07-19 中国人民解放军军事科学院军事医学研究院 基于lux报告系统的猪链球菌发光菌及其构建方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU219827B (hu) * 1992-10-02 2001-08-28 Lonza Ag. Biotechnológiai eljárás biotin előállítására
FI96697C (fi) * 1993-08-18 2001-05-16 Valio Oy Uudet Streptococcus thermophilus -kannat ja niiden käyttö antibioottie n määrittämiseen
JP2001516573A (ja) * 1997-09-18 2001-10-02 スミスクライン・ビーチャム・コーポレイション 抗微生物化合物のスクリーニング方法

Also Published As

Publication number Publication date
AU779263B2 (en) 2005-01-13
EP1728866A2 (en) 2006-12-06
DE60029107T2 (de) 2007-01-11
JP5295206B2 (ja) 2013-09-18
ES2267561T3 (es) 2007-03-16
CA2384496A1 (en) 2001-03-15
DE60029107D1 (de) 2006-08-10
EP1212429A2 (en) 2002-06-12
EP1728866B1 (en) 2009-11-11
EP1212429B1 (en) 2006-06-28
EP1728866A3 (en) 2007-03-14
ATE331790T1 (de) 2006-07-15
WO2001018195A2 (en) 2001-03-15
DE60043321D1 (de) 2009-12-24
JP2003509029A (ja) 2003-03-11
AU7126600A (en) 2001-04-10
WO2001018195A3 (en) 2001-06-21
ATE448309T1 (de) 2009-11-15
JP2011041577A (ja) 2011-03-03

Similar Documents

Publication Publication Date Title
JP5295206B2 (ja) ルシフェラーゼ発現カセットおよび使用法
JP2003509029A5 (https=)
KR102594240B1 (ko) 신규한 루시퍼라제 및 이를 이용하는 방법
RU2730038C2 (ru) Ферменты биосинтеза люциферина и их применение
US6737245B1 (en) Luciferase expression cassettes and methods of use
US7056728B2 (en) Compositions and methods for use thereof in modifying the genomes of microorganisms
US7090994B2 (en) Methods of screening for introduction of DNA into a target cell
JP2025522599A (ja) ルシフェラーゼ変異体及びその使用
RU2809367C2 (ru) Гиспидин-синтазы и их применение
RU2812474C2 (ru) Кофеилпируват-гидролазы и их применение
RU2822532C2 (ru) Поликетидсинтазы III типа и их применение
KR101387288B1 (ko) 구토독 산생 세레우스균의 검출 방법 및 상기 방법을 위한 프라이머 세트
WO2002008431A1 (en) Compositions and methods for use thereof in modifying the genomes of microorganisms
WO2023109981A9 (zh) 新型桡足类荧光素酶突变体及其应用
CN119931968A (zh) 一种荧光素酶突变体及其应用
Patterson Optimization of bacterial luciferase for expression in mammalian cells
BR122025022833A2 (pt) Novas luciferases e métodos de uso destas

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070803

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100816

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20101116

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20110106

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20110114

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140121

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Ref document number: 4669180

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term