JP4598395B2 - 直接書き込み式ナノリソグラフィーによるナノスケールチップからの核酸の沈着方法 - Google Patents

直接書き込み式ナノリソグラフィーによるナノスケールチップからの核酸の沈着方法 Download PDF

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JP4598395B2
JP4598395B2 JP2003549493A JP2003549493A JP4598395B2 JP 4598395 B2 JP4598395 B2 JP 4598395B2 JP 2003549493 A JP2003549493 A JP 2003549493A JP 2003549493 A JP2003549493 A JP 2003549493A JP 4598395 B2 JP4598395 B2 JP 4598395B2
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nucleic acid
substrate
dna
chip
tip
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JP2005512032A5 (https=
JP2005512032A (ja
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チャッド エイ. マーキン
エム. リネット デマース
デイビッド エス. ギンガー
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Northwestern University
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0241Drop counters; Drop formers
    • B01L3/0244Drop counters; Drop formers using pins
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05DPROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D5/00Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures
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    • B82NANOTECHNOLOGY
    • B82BNANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y40/00Manufacture or treatment of nanostructures
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03FPHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR
    • G03F7/00Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printing surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
    • G03F7/0002Lithographic processes using patterning methods other than those involving the exposure to radiation, e.g. by stamping
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01J2219/00387Applications using probes
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    • B01J2219/00497Features relating to the solid phase supports
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    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
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    • B01J2219/0061The surface being organic
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01J2219/00612Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
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    • B01J2219/00614Delimitation of the attachment areas
    • B01J2219/00617Delimitation of the attachment areas by chemical means
    • B01J2219/00619Delimitation of the attachment areas by chemical means using hydrophilic or hydrophobic regions
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01J2219/00583Features relative to the processes being carried out
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    • B01J2219/00623Immobilisation or binding
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    • B01J2219/0063Other, e.g. van der Waals forces, hydrogen bonding
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    • B01J2219/00583Features relative to the processes being carried out
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    • B01J2219/00632Introduction of reactive groups to the surface
    • B01J2219/00637Introduction of reactive groups to the surface by coating it with another layer
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    • B01J2219/00718Type of compounds synthesised
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  • Chemical & Material Sciences (AREA)
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  • Nanotechnology (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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JP2003549493A 2001-11-30 2002-12-02 直接書き込み式ナノリソグラフィーによるナノスケールチップからの核酸の沈着方法 Expired - Fee Related JP4598395B2 (ja)

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Application Number Priority Date Filing Date Title
US33759801P 2001-11-30 2001-11-30
US36292402P 2002-03-07 2002-03-07
PCT/US2002/038252 WO2003048314A2 (en) 2001-11-30 2002-12-02 Direct write nanolithographic deposition of nucleic acids from nanoscopic tips

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JP2005512032A JP2005512032A (ja) 2005-04-28
JP2005512032A5 JP2005512032A5 (https=) 2006-01-26
JP4598395B2 true JP4598395B2 (ja) 2010-12-15

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EP (1) EP1461596B1 (https=)
JP (1) JP4598395B2 (https=)
KR (1) KR100939421B1 (https=)
AU (1) AU2002360446A1 (https=)
CA (1) CA2468743A1 (https=)
TW (1) TWI311155B (https=)
WO (1) WO2003048314A2 (https=)

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WO2014052989A2 (en) * 2012-09-28 2014-04-03 Vibrant Holdings, Llc Methods, systems, and arrays for biomolecular analysis
US10286376B2 (en) 2012-11-14 2019-05-14 Vibrant Holdings, Llc Substrates, systems, and methods for array synthesis and biomolecular analysis
US10816553B2 (en) 2013-02-15 2020-10-27 Vibrant Holdings, Llc Methods and compositions for amplified electrochemiluminescence detection
US10538808B2 (en) 2017-05-26 2020-01-21 Vibrant Holdings, Llc Photoactive compounds and methods for biomolecule detection and sequencing
AU2019266303B2 (en) 2018-05-09 2025-12-18 Vibrant Holdings, Llc Methods of synthesizing a polynucleotide array using photactivated agents

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EP1461596A2 (en) 2004-09-29
AU2002360446A8 (en) 2003-06-17
KR20050044623A (ko) 2005-05-12
JP2005512032A (ja) 2005-04-28
EP1461596A4 (en) 2005-03-23
EP1461596B1 (en) 2013-07-17
TWI311155B (en) 2009-06-21
TW200302282A (en) 2003-08-01
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