JP4509999B2 - 医薬送達及び抗原提示システムとしてのペプチドナノ粒子 - Google Patents
医薬送達及び抗原提示システムとしてのペプチドナノ粒子 Download PDFInfo
- Publication number
- JP4509999B2 JP4509999B2 JP2006502449A JP2006502449A JP4509999B2 JP 4509999 B2 JP4509999 B2 JP 4509999B2 JP 2006502449 A JP2006502449 A JP 2006502449A JP 2006502449 A JP2006502449 A JP 2006502449A JP 4509999 B2 JP4509999 B2 JP 4509999B2
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- nanoparticles
- drug
- nanoparticle
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03003551 | 2003-02-17 | ||
| PCT/IB2004/000423 WO2004071493A1 (en) | 2003-02-17 | 2004-02-16 | Peptidic nanoparticles as drug delivery and antigen display systems |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006519781A JP2006519781A (ja) | 2006-08-31 |
| JP2006519781A5 JP2006519781A5 (https=) | 2007-03-29 |
| JP4509999B2 true JP4509999B2 (ja) | 2010-07-21 |
Family
ID=32864945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006502449A Expired - Fee Related JP4509999B2 (ja) | 2003-02-17 | 2004-02-16 | 医薬送達及び抗原提示システムとしてのペプチドナノ粒子 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8575110B2 (https=) |
| EP (1) | EP1594469B1 (https=) |
| JP (1) | JP4509999B2 (https=) |
| AT (1) | ATE371437T1 (https=) |
| DE (1) | DE602004008582T2 (https=) |
| WO (1) | WO2004071493A1 (https=) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1605972A2 (en) | 2003-03-26 | 2005-12-21 | Cytos Biotechnology AG | Hiv-peptide-carrier-conjugates |
| US7226473B2 (en) * | 2003-05-23 | 2007-06-05 | Brar Balbir S | Treatment of stenotic regions |
| US20040236414A1 (en) * | 2003-05-23 | 2004-11-25 | Brar Balbir S. | Devices and methods for treatment of stenotic regions |
| US9079765B2 (en) * | 2004-10-01 | 2015-07-14 | Midatech Ltd. | Nanoparticles comprising antigens and adjuvants, and immunogenic structures |
| US9492400B2 (en) | 2004-11-04 | 2016-11-15 | Massachusetts Institute Of Technology | Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals |
| US20070160628A1 (en) * | 2005-08-31 | 2007-07-12 | Birkett Ashley J | Stabilized virus-like particles and epitope display systems |
| EP1973608A1 (en) | 2005-12-14 | 2008-10-01 | Cytos Biotechnology AG | Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity |
| US9267937B2 (en) | 2005-12-15 | 2016-02-23 | Massachusetts Institute Of Technology | System for screening particles |
| US8367113B2 (en) | 2006-05-15 | 2013-02-05 | Massachusetts Institute Of Technology | Polymers for functional particles |
| MX2008015529A (es) | 2006-06-12 | 2009-01-13 | Cytos Biotechnology Ag | Procesos para empacar oligonucleotidos en particulas similares a virus de bacteriofagos de arn. |
| WO2007150030A2 (en) | 2006-06-23 | 2007-12-27 | Massachusetts Institute Of Technology | Microfluidic synthesis of organic nanoparticles |
| US9217129B2 (en) | 2007-02-09 | 2015-12-22 | Massachusetts Institute Of Technology | Oscillating cell culture bioreactor |
| US8889117B2 (en) * | 2007-02-15 | 2014-11-18 | Yale University | Modular nanoparticles for adaptable vaccines |
| US10265407B2 (en) | 2007-02-15 | 2019-04-23 | Yale University | Modular nanodevices for smart adaptable vaccines |
| WO2008124632A1 (en) | 2007-04-04 | 2008-10-16 | Massachusetts Institute Of Technology | Amphiphilic compound assisted nanoparticles for targeted delivery |
| EP2205256A4 (en) * | 2007-09-26 | 2012-10-24 | Dana Farber Cancer Inst Inc | REAGENTS TO TRIGGER IMMUNE REACTION |
| EP2630966B1 (en) | 2007-10-12 | 2017-04-19 | Massachusetts Institute of Technology | Vaccine nanotechnology |
| RU2540871C2 (ru) * | 2008-02-01 | 2015-02-10 | Альфа-О Пептидес Аг | Самоорганизующиеся пептидные наночастицы, полезные в качестве вакцин |
| EP2285832B1 (en) | 2008-05-16 | 2020-08-26 | Taiga Biotechnologies, Inc. | Antibodies and processes for preparing the same |
| EP2313108A4 (en) * | 2008-06-30 | 2013-06-12 | Us Army As Represented By The Secretary Of The Army | MALARIA VACCINE FROM SELF-ORGANIZING POLYPEPTIDE NANOTEHICLES |
| EP2318435B1 (en) | 2008-08-28 | 2015-12-23 | Taiga Biotechnologies, Inc. | Modulators of myc, methods of using the same, and methods of identifying agents that modulate myc |
| US8343498B2 (en) | 2008-10-12 | 2013-01-01 | Massachusetts Institute Of Technology | Adjuvant incorporation in immunonanotherapeutics |
| US8343497B2 (en) | 2008-10-12 | 2013-01-01 | The Brigham And Women's Hospital, Inc. | Targeting of antigen presenting cells with immunonanotherapeutics |
| US8591905B2 (en) | 2008-10-12 | 2013-11-26 | The Brigham And Women's Hospital, Inc. | Nicotine immunonanotherapeutics |
| US8277812B2 (en) | 2008-10-12 | 2012-10-02 | Massachusetts Institute Of Technology | Immunonanotherapeutics that provide IgG humoral response without T-cell antigen |
| US8580274B2 (en) | 2009-02-10 | 2013-11-12 | University Of The Ryukyus | Drug transporter, and adjuvant and vaccine each utilizing same |
| KR20120022984A (ko) * | 2009-04-21 | 2012-03-12 | 셀렉타 바이오사이언시즈, 인크. | Th1 편향 반응을 제공하는 면역나노치료법 |
| CA2762653A1 (en) * | 2009-05-27 | 2010-12-02 | Selecta Biosciences, Inc. | Immunomodulatory agent-polymeric compounds |
| CN107617110A (zh) * | 2009-08-26 | 2018-01-23 | 西莱克塔生物科技公司 | 诱导t细胞辅助的组合物 |
| AU2011258165B2 (en) | 2010-05-26 | 2016-11-17 | Selecta Biosciences, Inc. | Dose selection of adjuvanted synthetic nanocarriers |
| CN103221070B (zh) | 2010-08-30 | 2019-07-12 | 哈佛大学校长及研究员协会 | 用于狭窄病变和溶解血栓疗法的切变控制释放 |
| KR20140041505A (ko) | 2011-04-29 | 2014-04-04 | 셀렉타 바이오사이언시즈, 인크. | 조절 b 세포 유도를 위한 관용원성 합성 나노운반체 |
| JP2014521687A (ja) * | 2011-07-29 | 2014-08-28 | セレクタ バイオサイエンシーズ インコーポレーテッド | 体液性および細胞傷害性tリンパ球(ctl)免疫応答を生成する合成ナノキャリア |
| CN104136454A (zh) | 2011-10-12 | 2014-11-05 | 阿尔法-O肽股份公司 | 作为针对诺如病毒感染的疫苗的自装配肽纳米粒 |
| US9597385B2 (en) | 2012-04-23 | 2017-03-21 | Allertein Therapeutics, Llc | Nanoparticles for treatment of allergy |
| CN105188741A (zh) | 2013-04-03 | 2015-12-23 | 阿勒丁医疗公司 | 新型纳米颗粒组合物 |
| HUE052599T2 (hu) | 2013-05-03 | 2021-05-28 | Selecta Biosciences Inc | CD4+ szabályozó T-sejtek fokozására szolgáló eljárások és készítmények |
| TW201511774A (zh) * | 2013-09-18 | 2015-04-01 | Iner Aec Executive Yuan | 放射性標誌之主動標靶性醫藥組合物及其用途 |
| US10188136B2 (en) | 2016-02-16 | 2019-01-29 | Indian Institute Of Science Education And Research | Hydrophobin mimics: process for preparation thereof |
| KR20190092472A (ko) * | 2016-12-02 | 2019-08-07 | 타이가 바이오테크놀로지스, 인코포레이티드 | 나노입자 제제 |
| KR101955928B1 (ko) * | 2016-12-30 | 2019-03-08 | 경상대학교산학협력단 | 먹장어 유래 vlrb 단백질의 소수성 테일 도메인을 포함하는 다량체 다가 중합체 |
| CA3054172A1 (en) | 2017-02-23 | 2018-08-30 | Alpha-O Peptides Ag | Self-assembling protein nanoparticles encapsulating immunostimulatory nucleid acids |
| WO2018169811A1 (en) | 2017-03-11 | 2018-09-20 | Selecta Biosciences, Inc. | Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant |
| EA201991918A1 (ru) | 2017-03-23 | 2020-05-15 | Альфа-О Пептидс Аг | Самосборные белковые наночастицы со встроенными белками с шестиспиральным пучком |
| US11213582B2 (en) | 2018-08-08 | 2022-01-04 | The Regents Of The University Of California | Protection against recurrent genital herpes by therapeutic immunization with herpes simplex virus type 2 ribonucleotide reductase protein subunits |
| WO2020210231A1 (en) | 2019-04-08 | 2020-10-15 | Taiga Biotechnologies, Inc. | Compositions and methods for the cry opreservation of immune cells |
| EP3969041A4 (en) | 2019-05-14 | 2023-05-10 | Taiga Biotechnologies, Inc. | COMPOSITIONS AND METHODS FOR TREATMENT OF T-CELL DEPLETION |
| CN114207440A (zh) | 2019-06-04 | 2022-03-18 | 西莱克塔生物科技公司 | 聚乙二醇化尿酸酶的制剂和剂量 |
| US20220362370A1 (en) * | 2019-08-27 | 2022-11-17 | Tokyo Institute Of Technology | Composite protein monomer having non-structural protein of virus supported thereon, aggregate of composite protein monomer, and component vaccine comprising aggregate as active ingredient |
| CN111150841B (zh) * | 2019-12-31 | 2023-08-15 | 优锐生物医药科技(深圳)有限公司 | 一种主动免疫调控微粒及其制备方法和应用 |
| CN111150842B (zh) * | 2019-12-31 | 2023-09-05 | 优锐生物医药科技(深圳)有限公司 | 一种用于中和胃泌素的主动免疫调控微粒及其制备方法和应用 |
| EP3901261A1 (en) * | 2020-04-22 | 2021-10-27 | BioNTech RNA Pharmaceuticals GmbH | Coronavirus vaccine |
| US20230355540A1 (en) | 2020-09-29 | 2023-11-09 | Oxford University Innovation Limited | Stroke treatment |
| WO2022106860A1 (en) | 2020-11-20 | 2022-05-27 | Pécsi Tudományegyetem | Recombinant peptides for use in therapy |
| US20250042946A1 (en) | 2021-12-08 | 2025-02-06 | Oakgrove Bio Llc | Biological Production of Histidine-Rich Peptides |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2581394B1 (fr) * | 1985-05-02 | 1988-08-05 | Grp Genie Genetique | Particules ayant les proprietes immunogenes de l'antigene hbs et portant un site antigenique etranger aux epitopes portes par l'antigene hbs, vecteurs et cellules animales pour la production de telles particules et compositions contenant de telles particules pour la production de vaccins mixtes |
| US5041385A (en) * | 1986-11-01 | 1991-08-20 | Oxford Gene Systems Limited | Vector expressing fusion proteins and particles |
| US5877279A (en) * | 1994-10-13 | 1999-03-02 | Nanoframes, Llc | Materials for the production of nanometer structures and use thereof |
| US6756039B1 (en) * | 1999-05-10 | 2004-06-29 | The Regents Of The University Of California | Self assembling proteins |
| EP1191836B1 (en) * | 1999-06-25 | 2004-09-29 | Leslie H. Kondejewski | Polypeptide compositions formed using a coiled-coil template and methods of use |
| JP4085231B2 (ja) * | 2000-02-28 | 2008-05-14 | 株式会社ビークル | タンパク質中空ナノ粒子とそれを用いた物質運搬体、ならびに細胞への物質導入方法 |
-
2004
- 2004-02-16 WO PCT/IB2004/000423 patent/WO2004071493A1/en not_active Ceased
- 2004-02-16 US US10/545,676 patent/US8575110B2/en active Active
- 2004-02-16 EP EP04711429A patent/EP1594469B1/en not_active Expired - Lifetime
- 2004-02-16 DE DE602004008582T patent/DE602004008582T2/de not_active Expired - Lifetime
- 2004-02-16 JP JP2006502449A patent/JP4509999B2/ja not_active Expired - Fee Related
- 2004-02-16 AT AT04711429T patent/ATE371437T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US8575110B2 (en) | 2013-11-05 |
| DE602004008582T2 (de) | 2008-05-21 |
| DE602004008582D1 (de) | 2007-10-11 |
| JP2006519781A (ja) | 2006-08-31 |
| EP1594469B1 (en) | 2007-08-29 |
| US20070014804A1 (en) | 2007-01-18 |
| WO2004071493A1 (en) | 2004-08-26 |
| ATE371437T1 (de) | 2007-09-15 |
| EP1594469A1 (en) | 2005-11-16 |
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