JP4509999B2 - 医薬送達及び抗原提示システムとしてのペプチドナノ粒子 - Google Patents
医薬送達及び抗原提示システムとしてのペプチドナノ粒子 Download PDFInfo
- Publication number
- JP4509999B2 JP4509999B2 JP2006502449A JP2006502449A JP4509999B2 JP 4509999 B2 JP4509999 B2 JP 4509999B2 JP 2006502449 A JP2006502449 A JP 2006502449A JP 2006502449 A JP2006502449 A JP 2006502449A JP 4509999 B2 JP4509999 B2 JP 4509999B2
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- nanoparticles
- drug
- nanoparticle
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Animal Behavior & Ethology (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03003551 | 2003-02-17 | ||
| PCT/IB2004/000423 WO2004071493A1 (en) | 2003-02-17 | 2004-02-16 | Peptidic nanoparticles as drug delivery and antigen display systems |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006519781A JP2006519781A (ja) | 2006-08-31 |
| JP2006519781A5 JP2006519781A5 (https=) | 2007-03-29 |
| JP4509999B2 true JP4509999B2 (ja) | 2010-07-21 |
Family
ID=32864945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006502449A Expired - Fee Related JP4509999B2 (ja) | 2003-02-17 | 2004-02-16 | 医薬送達及び抗原提示システムとしてのペプチドナノ粒子 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8575110B2 (https=) |
| EP (1) | EP1594469B1 (https=) |
| JP (1) | JP4509999B2 (https=) |
| AT (1) | ATE371437T1 (https=) |
| DE (1) | DE602004008582T2 (https=) |
| WO (1) | WO2004071493A1 (https=) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004224761A1 (en) | 2003-03-26 | 2004-10-07 | Cytos Biotechnology Ag | HIV-peptide-carrier-conjugates |
| US7226473B2 (en) * | 2003-05-23 | 2007-06-05 | Brar Balbir S | Treatment of stenotic regions |
| US20040236414A1 (en) * | 2003-05-23 | 2004-11-25 | Brar Balbir S. | Devices and methods for treatment of stenotic regions |
| EP1793863B1 (en) * | 2004-10-01 | 2017-04-12 | Midatech Ltd. | Nanoparticles comprising antigens and adjuvants capable of stimulating t helper cells |
| WO2007001448A2 (en) | 2004-11-04 | 2007-01-04 | Massachusetts Institute Of Technology | Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals |
| US20070160628A1 (en) * | 2005-08-31 | 2007-07-12 | Birkett Ashley J | Stabilized virus-like particles and epitope display systems |
| CA2636139A1 (en) | 2005-12-14 | 2007-06-21 | Cytos Biotechnology Ag | Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity |
| WO2007070682A2 (en) | 2005-12-15 | 2007-06-21 | Massachusetts Institute Of Technology | System for screening particles |
| JP5630998B2 (ja) | 2006-05-15 | 2014-11-26 | マサチューセッツ インスティテュート オブ テクノロジー | 機能的粒子のためのポリマー |
| US8541559B2 (en) | 2006-06-12 | 2013-09-24 | Cytos Biotechnology Ag | Process for producing aggregated oligonucleotides |
| WO2007150030A2 (en) | 2006-06-23 | 2007-12-27 | Massachusetts Institute Of Technology | Microfluidic synthesis of organic nanoparticles |
| EP2134830A2 (en) | 2007-02-09 | 2009-12-23 | Massachusetts Institute of Technology | Oscillating cell culture bioreactor |
| US8889117B2 (en) * | 2007-02-15 | 2014-11-18 | Yale University | Modular nanoparticles for adaptable vaccines |
| US10265407B2 (en) | 2007-02-15 | 2019-04-23 | Yale University | Modular nanodevices for smart adaptable vaccines |
| JP2010523595A (ja) | 2007-04-04 | 2010-07-15 | マサチューセッツ インスティテュート オブ テクノロジー | ポリ(アミノ酸)ターゲッティング部分 |
| CA2700892A1 (en) * | 2007-09-26 | 2009-04-02 | Dana-Farber Cancer Institute, Inc. | Reagents for inducing an immune response |
| JP2011500569A (ja) | 2007-10-12 | 2011-01-06 | マサチューセッツ インスティテュート オブ テクノロジー | ワクチンナノテクノロジー |
| CA2713879C (en) * | 2008-02-01 | 2020-01-07 | Alpha-O Peptides Ag | Self-assembling peptide nanoparticles useful as vaccines |
| SG10201803982TA (en) | 2008-05-16 | 2018-07-30 | Taiga Biotechnologies Inc | Antibodies and processes for preparing the same |
| US20120015000A1 (en) * | 2008-06-30 | 2012-01-19 | David Lanar | Malaria vaccine of self-assembling polypeptide nanoparticles |
| DK3339321T3 (da) | 2008-08-28 | 2021-06-21 | Taiga Biotechnologies Inc | Modulatorer af myc, fremgangsmåder til anvendelse af samme og fremgangsmåder til at identificere stoffer der modulerer myc |
| US8277812B2 (en) | 2008-10-12 | 2012-10-02 | Massachusetts Institute Of Technology | Immunonanotherapeutics that provide IgG humoral response without T-cell antigen |
| US8591905B2 (en) | 2008-10-12 | 2013-11-26 | The Brigham And Women's Hospital, Inc. | Nicotine immunonanotherapeutics |
| US8343497B2 (en) | 2008-10-12 | 2013-01-01 | The Brigham And Women's Hospital, Inc. | Targeting of antigen presenting cells with immunonanotherapeutics |
| US8343498B2 (en) | 2008-10-12 | 2013-01-01 | Massachusetts Institute Of Technology | Adjuvant incorporation in immunonanotherapeutics |
| WO2010092963A1 (ja) | 2009-02-10 | 2010-08-19 | 国立大学法人 琉球大学 | 薬物運搬体並びにこれを利用したアジュバントおよびワクチン |
| JP2012524780A (ja) * | 2009-04-21 | 2012-10-18 | セレクタ バイオサイエンシーズ インコーポレーテッド | Th1バイアス応答をもたらす免疫ナノ治療薬(Immunonanotherapeutics) |
| BRPI1012036A2 (pt) | 2009-05-27 | 2017-10-10 | Selecta Biosciences Inc | nanocarreadores que possuem componentes com diferentes taxas de liberação |
| ES2641892T3 (es) * | 2009-08-26 | 2017-11-14 | Selecta Biosciences, Inc. | Composiciones que inducen la ayuda de las células T |
| CA2798739A1 (en) | 2010-05-26 | 2011-12-01 | Selecta Biosciences, Inc. | Nanocarrier compositions with uncoupled adjuvant |
| WO2012074588A2 (en) | 2010-08-30 | 2012-06-07 | President And Fellows Of Harvard College | Shear controlled release for stenotic lesions and thrombolytic therapies |
| MX374963B (es) | 2011-04-29 | 2025-03-06 | Selecta Biosciences Inc | Nanoportadores sintéticos tolerogénicos para reducir las respuestas de anticuerpos. |
| KR20140050698A (ko) | 2011-07-29 | 2014-04-29 | 셀렉타 바이오사이언시즈, 인크. | 체액성 및 세포독성 t 림프구(ctl) 면역 반응을 발생시키는 합성 나노운반체 |
| CA2851917A1 (en) | 2011-10-12 | 2013-04-18 | Alpha-O Peptides Ag | Self-assembling peptide nanoparticles as vaccines against infection with norovirus |
| US9597385B2 (en) | 2012-04-23 | 2017-03-21 | Allertein Therapeutics, Llc | Nanoparticles for treatment of allergy |
| KR102233251B1 (ko) | 2013-04-03 | 2021-03-26 | 엔-폴드 엘엘씨 | 신규 나노입자 조성물 |
| BR122020023215B1 (pt) | 2013-05-03 | 2022-11-22 | Selecta Biosciences, Inc | Composição e kit de nanocarreadores sintéticos tolerogênicos para reduzir ou prevenir anafilaxia em resposta a um antígeno não alergênico |
| TW201511774A (zh) * | 2013-09-18 | 2015-04-01 | Iner Aec Executive Yuan | 放射性標誌之主動標靶性醫藥組合物及其用途 |
| US10188136B2 (en) | 2016-02-16 | 2019-01-29 | Indian Institute Of Science Education And Research | Hydrophobin mimics: process for preparation thereof |
| EP3548425B1 (en) * | 2016-12-02 | 2023-03-29 | Taiga Biotechnologies, Inc. | Nanoparticle formulations |
| KR101955928B1 (ko) * | 2016-12-30 | 2019-03-08 | 경상대학교산학협력단 | 먹장어 유래 vlrb 단백질의 소수성 테일 도메인을 포함하는 다량체 다가 중합체 |
| WO2018154010A1 (en) | 2017-02-23 | 2018-08-30 | Alpha-O Peptides Ag | Self-assembling protein nanoparticles encapsulating immunostimulatory nucleid acids |
| ES3036482T3 (en) | 2017-03-11 | 2025-09-19 | Cartesian Therapeutics Inc | Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant |
| EP3600402A1 (en) | 2017-03-23 | 2020-02-05 | Alpha-O Peptides AG | Self-assembling protein nanoparticles with built-in six-helix bundle proteins |
| US11213582B2 (en) | 2018-08-08 | 2022-01-04 | The Regents Of The University Of California | Protection against recurrent genital herpes by therapeutic immunization with herpes simplex virus type 2 ribonucleotide reductase protein subunits |
| CN113874033A (zh) | 2019-04-08 | 2021-12-31 | 泰加生物工艺学公司 | 用于冷冻保存免疫细胞的组合物和方法 |
| EP3969041A4 (en) | 2019-05-14 | 2023-05-10 | Taiga Biotechnologies, Inc. | COMPOSITIONS AND METHODS FOR TREATMENT OF T-CELL DEPLETION |
| AU2020287627A1 (en) | 2019-06-04 | 2021-11-18 | Selecta Biosciences, Inc. | Formulations and doses of PEGylated uricase |
| US20220362370A1 (en) * | 2019-08-27 | 2022-11-17 | Tokyo Institute Of Technology | Composite protein monomer having non-structural protein of virus supported thereon, aggregate of composite protein monomer, and component vaccine comprising aggregate as active ingredient |
| CN111150841B (zh) * | 2019-12-31 | 2023-08-15 | 优锐生物医药科技(深圳)有限公司 | 一种主动免疫调控微粒及其制备方法和应用 |
| CN111150842B (zh) * | 2019-12-31 | 2023-09-05 | 优锐生物医药科技(深圳)有限公司 | 一种用于中和胃泌素的主动免疫调控微粒及其制备方法和应用 |
| IL297419B2 (en) * | 2020-04-22 | 2025-02-01 | BioNTech SE | Coronavirus vaccine |
| KR20230088732A (ko) | 2020-09-29 | 2023-06-20 | 옥스포드 유니버시티 이노베이션 리미티드 | 뇌졸중 치료 |
| WO2022106860A1 (en) | 2020-11-20 | 2022-05-27 | Pécsi Tudományegyetem | Recombinant peptides for use in therapy |
| US20250042946A1 (en) | 2021-12-08 | 2025-02-06 | Oakgrove Bio Llc | Biological Production of Histidine-Rich Peptides |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2581394B1 (fr) * | 1985-05-02 | 1988-08-05 | Grp Genie Genetique | Particules ayant les proprietes immunogenes de l'antigene hbs et portant un site antigenique etranger aux epitopes portes par l'antigene hbs, vecteurs et cellules animales pour la production de telles particules et compositions contenant de telles particules pour la production de vaccins mixtes |
| US5041385A (en) * | 1986-11-01 | 1991-08-20 | Oxford Gene Systems Limited | Vector expressing fusion proteins and particles |
| US5877279A (en) * | 1994-10-13 | 1999-03-02 | Nanoframes, Llc | Materials for the production of nanometer structures and use thereof |
| US6756039B1 (en) * | 1999-05-10 | 2004-06-29 | The Regents Of The University Of California | Self assembling proteins |
| WO2001000010A1 (en) * | 1999-06-25 | 2001-01-04 | Kondejewski Leslie H | Polypeptide compositions formed using a coiled-coil template and methods of use |
| JP4085231B2 (ja) * | 2000-02-28 | 2008-05-14 | 株式会社ビークル | タンパク質中空ナノ粒子とそれを用いた物質運搬体、ならびに細胞への物質導入方法 |
-
2004
- 2004-02-16 DE DE602004008582T patent/DE602004008582T2/de not_active Expired - Lifetime
- 2004-02-16 JP JP2006502449A patent/JP4509999B2/ja not_active Expired - Fee Related
- 2004-02-16 WO PCT/IB2004/000423 patent/WO2004071493A1/en not_active Ceased
- 2004-02-16 US US10/545,676 patent/US8575110B2/en active Active
- 2004-02-16 AT AT04711429T patent/ATE371437T1/de not_active IP Right Cessation
- 2004-02-16 EP EP04711429A patent/EP1594469B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1594469A1 (en) | 2005-11-16 |
| DE602004008582T2 (de) | 2008-05-21 |
| JP2006519781A (ja) | 2006-08-31 |
| EP1594469B1 (en) | 2007-08-29 |
| US8575110B2 (en) | 2013-11-05 |
| WO2004071493A1 (en) | 2004-08-26 |
| DE602004008582D1 (de) | 2007-10-11 |
| ATE371437T1 (de) | 2007-09-15 |
| US20070014804A1 (en) | 2007-01-18 |
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