JP4467973B2 - 非機能性ｐ２ｘ７リセプターに対応する抗体、癌及びその他の症状の診断及び治療 - Google Patents

非機能性ｐ２ｘ７リセプターに対応する抗体、癌及びその他の症状の診断及び治療 Download PDF

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JP4467973B2
JP4467973B2 JP2003525032A JP2003525032A JP4467973B2 JP 4467973 B2 JP4467973 B2 JP 4467973B2 JP 2003525032 A JP2003525032 A JP 2003525032A JP 2003525032 A JP2003525032 A JP 2003525032A JP 4467973 B2 JP4467973 B2 JP 4467973B2
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receptor
functional
proline
antibody
disease
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Japanese (ja)
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JP2005513416A (ja
JP2005513416A5 (fr
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アンガス・ギドレイ−バード
ジュリアン・アレクサンダー・バーデン
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イントリート ピーティーワイ リミテッド
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Priority claimed from AUPR7431A external-priority patent/AUPR743101A0/en
Priority claimed from AUPR7430A external-priority patent/AUPR743001A0/en
Priority claimed from PCT/AU2002/000061 external-priority patent/WO2002057306A1/fr
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003525032A 2001-09-03 2002-09-03 非機能性ｐ２ｘ７リセプターに対応する抗体、癌及びその他の症状の診断及び治療 Expired - Lifetime JP4467973B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
AUPR7430 2001-09-03
AUPR7431A AUPR743101A0 (en) 2001-09-03 2001-09-03 A cancer therapeutic
AUPR7431 2001-09-03
AUPR7430A AUPR743001A0 (en) 2001-09-03 2001-09-03 Diagnosis and treatment of irritable bowel syndrome
AUPCT/AU02/00061 2002-01-17
PCT/AU2002/000061 WO2002057306A1 (fr) 2001-01-17 2002-01-17 Anticorps du recepteur p2x7 non fonctionnel, diagnostic et traitement de cancers et autres etats pathologiques
PCT/AU2002/001204 WO2003020762A1 (fr) 2001-09-03 2002-09-03 Anticorps au recepteur p2x7 non fonctionnel, diagnostic et traitement de cancers et d'autres conditions

Publications (3)

Publication Number Publication Date
JP2005513416A JP2005513416A (ja) 2005-05-12
JP2005513416A5 JP2005513416A5 (fr) 2008-05-15
JP4467973B2 true JP4467973B2 (ja) 2010-05-26

Family

ID=41706691

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003525032A Expired - Lifetime JP4467973B2 (ja) 2001-09-03 2002-09-03 非機能性ｐ２ｘ７リセプターに対応する抗体、癌及びその他の症状の診断及び治療

Country Status (9)

Country Link
JP (1) JP4467973B2 (fr)
CN (2) CN101445555B (fr)
AU (1) AU2002322192B2 (fr)
CA (1) CA2459348C (fr)
MY (1) MY142283A (fr)
NZ (2) NZ549019A (fr)
TW (1) TWI329648B (fr)
WO (1) WO2003020762A1 (fr)
ZA (1) ZA200402630B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100497385C (zh) 2001-01-17 2009-06-10 因特里特控股有限公司 针对非功能性p2x7受体的抗体及其在癌症和其它病情的诊断和治疗中的用途
JP4746987B2 (ja) * 2002-12-05 2011-08-10 ケーエルエー−テンカー コーポレイション 散乱計測を用いてオーバレイ誤差を検出する装置および方法
EP1615991A4 (fr) 2003-04-03 2007-12-19 Bristol Myers Squibb Co Polynucleotide codant un nouveau variant d'epissage p2x7 humain appele hbmyp2x7v
US8124730B1 (en) 2004-04-02 2012-02-28 Bristol-Myers Squibb Company Polynucleotide encoding a novel human P2X7 splice variant, HBMYP2X7v
US7767789B2 (en) * 2005-06-02 2010-08-03 University Hopitals of Cleveland Truncated proteins as cancer markers
US20100036101A1 (en) * 2006-10-10 2010-02-11 Angus Gidley-Baird Antibodies against non functional p2x7 receptor
AU2007306924A1 (en) * 2006-10-10 2008-04-17 Biosceptre International Limited Hybridomas producing antibodies against non functional P2X7 receptor
AU2013238152B2 (en) * 2007-09-14 2015-09-24 Biosceptre International Limited Purinergic (P2X) receptors in extra-cellular body fluid
WO2009033233A1 (fr) 2007-09-14 2009-03-19 Biosceptre International Limited Nouveaux épitopes p2x7
ATE542139T1 (de) * 2007-09-14 2012-02-15 Biosceptre Int Ltd Purinerge (p2x)-rezeptoren in extrazellulärer körperflüssigkeit
CN102143978B (zh) 2008-07-04 2015-02-18 生物权威国际有限公司 抗p2x7肽和表位
CN101469352B (zh) * 2008-08-29 2011-12-21 苏州福英基因科技有限公司 一种早期子宫癌原位杂交检测试剂盒
ES2904911T3 (es) 2009-08-20 2022-04-06 Biosceptre Aust Pty Ltd Anticuerpos anti-receptor P2X7 y fragmentos de los mismos
EP3321285B1 (fr) 2009-12-24 2019-04-24 Biosceptre (Aust) Pty Ltd Anticorps dirigés contre les récepteurs p2x7 oligomères non fonctionnels
ES2656971T3 (es) 2010-09-10 2018-03-01 Biosceptre (Aust) Pty Ltd Tratamientos para el cáncer en animales de compañía con un anticuerpo anti P2X7
CN103702683B (zh) 2011-07-01 2017-07-04 生物权威(澳大利亚)有限责任公司 联合治疗
EP2990800A1 (fr) * 2014-08-29 2016-03-02 Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol Neprilysin comme marqueur pronostique pour l'insuffisance cardiaque
EP3347474B1 (fr) 2015-09-11 2020-11-04 Biosceptre (UK) Limited Récepteurs d'antigènes chimériques et leurs utilisations
EP3528789A4 (fr) * 2016-10-21 2020-06-24 Biosceptre UK Limited Particules cytotoxiques
CN110054691B (zh) * 2019-05-09 2021-09-07 潍坊医学院 一种抗人p2rx7单克隆抗体的杂交瘤细胞系

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133434A (en) * 1997-04-28 2000-10-17 Glaxo Group Limited Purinergic receptor
CN100497385C (zh) * 2001-01-17 2009-06-10 因特里特控股有限公司 针对非功能性p2x7受体的抗体及其在癌症和其它病情的诊断和治疗中的用途

Also Published As

Publication number Publication date
JP2005513416A (ja) 2005-05-12
ZA200402630B (en) 2005-06-29
CN1625565A (zh) 2005-06-08
NZ549019A (en) 2008-05-30
MY142283A (en) 2010-11-15
CA2459348C (fr) 2013-06-18
CN101445555A (zh) 2009-06-03
AU2002322192B2 (en) 2008-05-01
NZ565994A (en) 2010-02-26
WO2003020762A1 (fr) 2003-03-13
CA2459348A1 (fr) 2003-03-13
CN100497386C (zh) 2009-06-10
CN101445555B (zh) 2013-07-03
TWI329648B (en) 2010-09-01

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US10450380B2 (en) Polypeptide immunogen for generating an antibody to non-functional P2X7 receptor
JP4467973B2 (ja) 非機能性ｐ２ｘ７リセプターに対応する抗体、癌及びその他の症状の診断及び治療
JP2004528286A5 (fr)
AU2002322192A1 (en) Antibodies to non-functional P2X7receptor, diagnosis and treatment of cancers and other conditions
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