JP4459303B2 - 炎症反応に起因する哺乳類の疾病の治療方法およびその組成物 - Google Patents

炎症反応に起因する哺乳類の疾病の治療方法およびその組成物 Download PDF

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Publication number
JP4459303B2
JP4459303B2 JP51274197A JP51274197A JP4459303B2 JP 4459303 B2 JP4459303 B2 JP 4459303B2 JP 51274197 A JP51274197 A JP 51274197A JP 51274197 A JP51274197 A JP 51274197A JP 4459303 B2 JP4459303 B2 JP 4459303B2
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pyruvate
inflammatory
composition
mediator
drugs
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Japanese (ja)
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JPH10509463A (ja
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カーツ,スタンリー,イー
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セルラー サイエンセズ インコーポレイテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP51274197A 1995-09-19 1996-09-06 炎症反応に起因する哺乳類の疾病の治療方法およびその組成物 Expired - Lifetime JP4459303B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US396295P 1995-09-19 1995-09-19
US60/003,962 1995-09-19
PCT/US1996/014304 WO1997010818A1 (fr) 1995-09-19 1996-09-06 Methode et composition de traitement de maladies mammaliennes provoquees par une reaction inflammatoire

Publications (2)

Publication Number Publication Date
JPH10509463A JPH10509463A (ja) 1998-09-14
JP4459303B2 true JP4459303B2 (ja) 2010-04-28

Family

ID=21708422

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51274197A Expired - Lifetime JP4459303B2 (ja) 1995-09-19 1996-09-06 炎症反応に起因する哺乳類の疾病の治療方法およびその組成物

Country Status (10)

Country Link
EP (1) EP0804181A4 (fr)
JP (1) JP4459303B2 (fr)
AU (1) AU719332B2 (fr)
CA (1) CA2205112C (fr)
IL (1) IL119225A (fr)
MX (1) MX9703653A (fr)
NZ (1) NZ306832A (fr)
TW (1) TW434012B (fr)
WO (1) WO1997010818A1 (fr)
ZA (1) ZA967833B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2373611C (fr) * 1999-05-14 2009-06-23 Cellular Sciences, Inc. Methode et composition permettant de traiter les maladies du nez et des sinus provoquees par une reaction inflammatoire chez les mammiferes
JP2004528307A (ja) * 2001-03-15 2004-09-16 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション サイトカインにより媒介される炎症性状態の治療のためのピルベートおよび/またはその誘導体の使用方法
US6623723B2 (en) * 2001-08-21 2003-09-23 Cellular Sciences Inc. Method for treating bronchial constriction and bronchospasm
US6689810B2 (en) * 2001-08-21 2004-02-10 Cellular Sciences, Inc. Method for treating pulmonary disease states in mammals by altering indigenous in vivo levels of nitric oxide
US20030105162A1 (en) * 2001-08-21 2003-06-05 Celluar Sciences, Inc. Method for treating bronchial constriction and bronchospasm
US8076373B2 (en) * 2001-09-11 2011-12-13 North Cell Pharmacetical Method for treating mammalian diseases and injuries caused by the over-expression of peroxynitrite
JP5630750B2 (ja) * 2008-03-18 2014-11-26 国立大学法人 岡山大学 興奮性化学伝達調節剤およびそのスクリーニング法
US11571455B2 (en) 2013-04-11 2023-02-07 Vanderbilt University Methods and compositions for treating alcoholic liver disease
JP2020524144A (ja) 2017-06-16 2020-08-13 ヴァンダービルト ユニヴァーシティ 微生物性炎症を処置するための方法および組成物
EP3797766A1 (fr) * 2019-09-24 2021-03-31 Evonik Operations GmbH Compositions à utiliser pour réduire l'inflammation
KR20220097972A (ko) * 2019-11-14 2022-07-08 메르크 파텐트 게엠베하 세포 배양 배지

Family Cites Families (26)

* Cited by examiner, † Cited by third party
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FR1857M (fr) * 1962-03-08 1963-06-10 Roussel Uclaf Nouveau médicament notamment pour le traitement des maladies d'origine virale.
US3279997A (en) * 1963-10-22 1966-10-18 Herbert D Schneyer Enteric coated calcium lactate tablets containing an antihistamine and thiamine chloride
US3879537A (en) * 1973-09-04 1975-04-22 Scott Eugene J Van Treatment of ichthyosiform dermatoses
US3988470A (en) * 1974-02-25 1976-10-26 Scott Eugene J Van Treatment of palmar and plant disturbed keratosis
US4158057A (en) * 1975-03-28 1979-06-12 Stanko Ronald T Prevention of the accumulation of fatty deposits in the liver
US4021572A (en) * 1975-07-23 1977-05-03 Scott Eugene J Van Prophylactic and therapeutic treatment of acne vulgaris utilizing lactamides and quaternary ammonium lactates
US4197316A (en) * 1975-07-23 1980-04-08 Scott Eugene J Van Treatment of dry skin
US4234599A (en) * 1978-10-04 1980-11-18 Scott Eugene J Van Treatment of skin keratoses with α-hydroxy acids and related compounds
US4351835A (en) * 1981-04-01 1982-09-28 Montefiore Hospital Method for preventing body fat deposition in mammals
US4415576A (en) * 1981-04-01 1983-11-15 Montefiore Hospital Method for preventing body fat deposition in mammals
US4521375A (en) * 1982-11-23 1985-06-04 Coopervision, Inc. Sterilizing treatment with hydrogen peroxide and neutralization of residual amounts thereof
DE3302694A1 (de) * 1983-01-27 1984-08-02 Retheto Filmtechnik Theilemann & Co, 8000 München Mundpflegemittel
WO1986000227A1 (fr) * 1984-06-22 1986-01-16 Veech Richard L Solutions electrolytiques et leur utilisation in vivo
US4696917A (en) * 1985-08-01 1987-09-29 Lindstrom Richard L Irrigation solution
JPS63135370A (ja) * 1986-11-26 1988-06-07 Grelan Pharmaceut Co Ltd 抗アレルギ−剤
IN168530B (fr) * 1987-11-06 1991-04-20 Lyphomed Inc
WO1990000900A1 (fr) * 1988-07-20 1990-02-08 Amgen Inc. Procede de traitement de troubles inflammatoires par reduction de l'activation phagocytaire
JP2794021B2 (ja) * 1988-11-02 1998-09-03 エーザイ株式会社 アゼラスチン或いはその塩類含有経皮適用製剤
EP0477345A1 (fr) * 1990-03-30 1992-04-01 Amgen Inc. Facteurs d'inhibition des bouffees respiratoires
US5210098A (en) * 1990-09-21 1993-05-11 Regents Of The University Of Minnesota Use of pyruvate to treat acute renal failure
US5296370A (en) * 1990-10-04 1994-03-22 Rutgers, The State University Repair medium for the resuscitation of injured cells
US5648380A (en) * 1991-03-01 1997-07-15 Warner-Lambert Company Anti-inflammatory wound healing compositions and methods for preparing and using same
WO1993016690A1 (fr) * 1992-02-25 1993-09-02 Warner-Lambert Company Compositions cytoprotectrices contenant du pyruvate et des antioxydants
US5256697A (en) * 1992-04-16 1993-10-26 Abbott Laboratories Method of administering pyruvate and methods of synthesizing pyruvate precursors
JP3236658B2 (ja) * 1992-04-27 2001-12-10 花王株式会社 気管支拡張剤
US5536751A (en) * 1994-05-09 1996-07-16 The United States Of America As Represented By The Secretary Of The Army Pharmaceutical alpha-keto carboxylic acid compositions method of making and use thereof

Also Published As

Publication number Publication date
EP0804181A1 (fr) 1997-11-05
ZA967833B (en) 1997-06-02
AU6915996A (en) 1997-04-09
WO1997010818A1 (fr) 1997-03-27
AU719332B2 (en) 2000-05-04
IL119225A0 (en) 1996-12-05
NZ306832A (en) 2001-04-27
EP0804181A4 (fr) 2005-02-02
JPH10509463A (ja) 1998-09-14
IL119225A (en) 2000-09-28
CA2205112C (fr) 2008-11-18
TW434012B (en) 2001-05-16
MX9703653A (es) 1998-07-31
CA2205112A1 (fr) 1997-03-27

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