JP4137047B2 - Emulsified cosmetics - Google Patents

Description

  The present invention relates to an emulsified cosmetic, and more particularly to an emulsified cosmetic excellent in stability and feel.

In recent years, coenzyme Q10 is often blended in cosmetics for the purpose of anti-aging action, antioxidant action and the like (see Patent Documents 1 to 3).
However, since coenzyme Q10 has low solubility, precipitation and the like occur, and the deterioration of palatability occurs with a decrease in the effect. This is particularly remarkable when coenzyme Q10 coexists with other water-soluble active ingredients. Until now, attempts have been made to prevent crystallization of coenzyme Q10 by coexisting with a large amount of an oil agent and a polyhydric alcohol (see Patent Document 4). There is a limit to the feel that is strong and can be expressed as a cosmetic.
JP 2002-293731 A JP 2003-342159 A JP 2004-224742 A JP 2003-238396 A

  Therefore, it has been difficult to prepare a cosmetic material that contains Coenzyme Q10 and has excellent feel and stability.

  As a result of intensive studies to achieve the above object, it was found that coenzyme Q10 and a water-soluble physiologically active substance can be stably blended in an emulsion preparation using a specific oil, and that it is excellent in touch and completed the present invention. did.

That is, the first invention is (A) and coenzyme Q10, (B) a water-soluble physiologically active substance, (C) dioctyl carbonate, carbonate dicapryl, and one or more oil selected et or methylphenyl polysiloxanylalkyl down It is in the emulsified cosmetic characterized by containing this.

  Further, the second present invention provides (B) a mitochondrial activator wherein the water-soluble physiologically active substance is selected from carnitine salt, γ-aminobutyric acid, lipoic acid, yeast extract, or arnica, aloe, altea, ashitaba, acerola, Apricot, almond, acha, akebi, anise, avocado, nintendo, nettle, strawberry, fennel, turmeric, prickly pear, oolong tea, usvenia mallow, ages, echinacea, oat, enmeiso, edelweiss, dutch mustard, grasshopper, cormorant, cormorant Orange, okra, olive, cassis, valerian, persimmon, fire thorns, chamomile, carrot, kawara mugi, oats, licorice, cucumber, kiwi, kina, kiraya, kizuta, gabba tea, mallet, clara, kumazasa, mulberry, walnut, gray Fruit, Ganoderma, Gentian, Geto, Burdock, Comfrey, Wheat germ, Salvia, Hawthorn, Saisin, Saitai, Sanshi, Shimotake, Prunus, Shichigenge, Shobu, Ginger, Shikon, Perilla, Birch, Peonies, Giant, Seeker, Simon, Horsetail, star fruit, mallow, cucumber, hawthorn, pheasant, sage, assembly, soybean, daidai, thyme, tachibana, tacitrus, tamarind, tea, clove, chimpi, strawberry, dokudami, toki, tonin, spruce, tomato, Dokudami, Tokisenka, wisteria tea, tormentilla, corn, green tea, elderberry, garlic, carrot, wild rose, papuamesu, hibiscus, parsley, banana, rose, pearl barley Me, Pecannut, Cypress, Hyssop, Sandalwood, Loquat, Prunes, Grapes, Fusazakisen, Fusofutsugi, Futomomo, Peppermint, Safflower, Loofah, Pterosa, White Genepi, Butterberry, Bodhi Tree, Button Bow Fu, Button, Hop, Quince , Mika, Maronie, Pine, Citrus, Mucloj, Melissa, Peach, Cornflower, Saxifrage, Eucalyptus, Lily, Persimmon, Yokuinin, Artemisia, Orchid, Lime, Lavender, Lettuce, Apple, Ryukyu Artemisia, Rooibos, Forsythia, Lemon, Lemon Balm , Water and / or water-soluble organic solvent extract of plants, seaweeds or fungi selected from rosehip, rosemary, green algae, red algae, brown algae, broomfish, shiitake mushrooms, chestnut mushrooms, white mushrooms, white jellyfish, litchi, cordyceps Acid bacterium culture solution, in the emulsified cosmetic which is characterized in that at least one selected from the yeast culture.

  The present invention provides an emulsified cosmetic excellent in stability and usability.

  Hereinafter, embodiments of the invention will be described in detail.

  (A) Coenzyme Q10 used in the emulsified cosmetic of the present invention is also known as ubidecarenone or coenzyme Q10, and is a known substance. The blending amount is preferably in the range of 0.0001 to 1% by mass based on the total amount of the emulsified cosmetic. When the upper limit of the blending amount is exceeded, there may be a problem in stability, and an effect commensurate with the exceeding blending amount cannot be expected. It may not be possible.

  The water-soluble physiologically active substance (B) used in the emulsified cosmetic of the present invention is water-soluble and protects skin tissue and / or acts on skin cells and organelles to maintain skin homeostasis and functions. It is a substance that promotes and maintains anti-oxidation, radical scavenging, ultraviolet absorption, Maillard reaction inhibition, tyrosinase inhibition, mitochondrial activation, blood circulation promotion, hyaluronic acid production promotion, collagen production It is a substance having a promoting action, an anti-inflammatory action, a sebum secretion inhibitory action, a cell proliferation action, a keratinization promoting action, an inflammatory property, a cytokine production inhibiting action, a ceramide synthesis promoting action and the like. Hereinafter, a specific example will be described.

  Examples of the water-soluble physiologically active substance (B) used in the emulsified cosmetic of the present invention include mitochondrial activators selected from carnitine salts, γ-aminobutyric acid, lipoic acid, and yeast extract. These are known substances such as carnitine chloride (manufactured by Kongo Chemical Co., Ltd.), BIO GABA (manufactured by Kyowa Hakko Co., Ltd.), lipoic acid (manufactured by Oriza Yuka Co., Ltd.), dismutin BTJ (manufactured by Pentafarm), cytodyne (Brooks). Yeast Liquid ZB (manufactured by Ichimaru Falcos), chitocatalyzer (manufactured by BIO-DELL), PSEUDO FILAGGRIN (manufactured by Arch Personal Care Product), TONISKIN (manufactured by SILAB), and the like. The blending amount is based on the total amount of the emulsified cosmetic, and in the case of an extract, a range of 0.01 to 5% by mass in terms of dry solid content is preferable. Even if the upper limit of the blending amount is exceeded, an effect commensurate with the exceeding blending amount cannot be expected, and if the blending amount is less than the lower limit, the object of the present invention may not be achieved.

Also Arnica, Aloe, Altea, Ashitaba, Acerola, Apricot, Almond, Achacha, Akebi, Anise, Avocado, Inchinkou, Nettle, Strawberry, Fennel, Turmeric, Prickly Pear, Oolong Tea, Usvenia Oy, Ages, Echinacea, Enbacu Dutch mustard, buckwheat, buckwheat, oren, hypericum, orange, okra, olive, cassis, valerian, firewood, fire thorns, chamomile, carrot, sagebrush, oats, licorice, cucumber, kiwi, kina, kiraya, kizuta, gaba tea, Kiso, Clara, Kumazasa, Mulberry, Walnut, Grapefruit, Gentian pepper, Gentian, Geto, Burdock, Comfrey, Wheat germ, Salvia, Hawthorn, Saishin, Saitai, Sanshishi, Shi Camellia, juyaku, shichihenge, ginger, ginger, shikon, white birch, peonies, elephant, seeker, simmon, Japanese horsetail, starfruit, mallow, cucumber, hawthorn, kizuta, sage, assembly, soybean, daidai, thyme, tachibana , Tachi musk, tamarind, tea, clove, chimpi, persimmon, dokudami, touki, tonin, spruce, tomato, dokudami, duckweed, wisteria tea, tormentilla, corn, nigahakka, elderberry, garlic, carrot, Novara, papuames, hibiscus, parsley , Banana, rose, pearl barley, green peas, pecan nuts, cypress, hyssop, sandalwood, loquat, prunes, grapes, chrysanthemum, daffodil, yellow peach, peppermint Safflower, loofah, hera plantain, white genepi, cypress, linden tree, button boofish, button, hop, quince, mica, maronier, pine, mandarin, mukuroji, melissa, peach, cornflower, saxifrage, eucalyptus, lily, moth, yokoinin, mugwort , Orchid, lime, lavender, lettuce, apple, Ryukyu mugwort, rooibos, forsythia, lemon, lemon balm, rosehip, rosemary, green algae, red algae, brown algae, broomfish, shiitake mushrooms, mushrooms, sardine mushrooms, white jellyfish, ganoderma, cordyceps Water, glycerin, propylene glycol, ethanol, butylene glycol and other water-soluble organic solvents, or mixtures thereof, from selected plants, seaweed or whole plants, leaves, stems, roots, fruits, seeds, flowers, fruiting bodies, etc. Extracted by There is a gift. Chlorophyll is a colored extract extracted from a plant body, and corresponds to a plant extract extracted with water and / or a water-soluble organic solvent of the present invention. Lactic acid bacteria culture fluid and yeast culture fluid are known substances, and can be used regardless of the presence or absence of removal of bacterial cells. The blending amount of these extracts or culture solutions is preferably in the range of 0.0001 to 5% by mass in terms of dry solid content based on the total amount of the emulsified cosmetic. Even if the upper limit of the blending amount is exceeded, an effect commensurate with the exceeding blending amount cannot be expected, and the blending amount less than the lower limit may not achieve the object of the present invention.

  In the emulsified cosmetic of the present invention, (C) one or more oil agents selected from dialkyl carbonate, methylphenyl polysiloxane, and liquid higher fatty acid are used.

  Dialkyl carbonate is a known substance, and for example, dioctyl carbonate and diethylhexyl carbonate can be used.

  Methylphenylpolysiloxane is also a known substance, and for example, silicon FZ209 (manufactured by Nihon Unicar) can be used.

  Liquid higher fatty acids are known substances, and examples include unsaturated fatty acids and branched fatty acids. Examples of unsaturated fatty acids include oleic acid and palmitooleic acid. Examples of branched fatty acids include vegetable oils such as soybean oil and cottonseed oil, or Examples thereof include branched fatty acids extracted from hydrogenated oil and branched fatty acids produced as a by-product in the production of dimer acid using vegetable oil as a raw material. In particular, unsaturated fatty acids are desirable in terms of palatability such as odor, and isostearic acid EX (manufactured by Higher Alcohol Industry Co., Ltd.) can be used.

The blending amount of one or more oils selected from (C) dialkyl carbonate, methylphenyl polysiloxane, and liquid higher fatty acid used in the emulsified cosmetic of the present invention is 0.01 to 70 based on the total amount of the emulsified cosmetic. Mass% is preferred. Even if the upper limit of the blending amount is exceeded, an effect commensurate with the exceeding blending amount cannot be expected, and if the blending amount is less than the lower limit, the object of the present invention may not be achieved.

  In particular, dioctyl carbonate has the good solubility of coenzyme Q10 and can be easily prepared at a low temperature, and can be said to be the most suitable oil agent.

  The emulsified cosmetic of the present invention can take any of a water-in-oil type, an oil-in-water type, and a multi-emulsion. As the usage purpose of the cosmetic, it can be applied to, for example, moisturizing, anti-aging, whitening, pack, massage, sunscreen, makeup base, foundation, lip balm, cleansing and the like.

In addition to the above essential components, the emulsified cosmetic of the present invention includes tar pigments, colored pigments such as iron oxide, preservatives such as parabens and phenoxyethanol, squalanes such as olive squalane, rice squalane and shark squalane, dimethyl Silicone oil such as polysiloxane and cyclic silicone (excluding methylphenylpolysiloxane), hydrocarbons such as paraffin, liquid paraffin, petrolatum, olefin oligomer, squalane, rice germ oil, rice bran oil, jojoba oil, castor oil, safflower oil , Olive oil, macadamia nut oil, sunflower oil, avocado oil, canola oil, kyonin oil and other vegetable oils, triisostearic acid glyceride, tri (capryl-capric) glyceride, tri-2-ethylhexanoic acid glyceryl, tristearic acid glyceride, tribehenic acid G Cerides, triglycerides such as triglyceride, caprylic, capryline, myristic, stearic acid, trimyristic acid glyceride, triisopalmitic acid glyceride, waxes such as beeswax, mole, carnauba wax, octyldodecyl myristate, cetyl palmitate, isostearic acid Ester oil such as isostearyl and isopropyl myristate, lower alcohols such as ethanol, cetanol, behenyl alcohol, isostearyl alcohol, jojoba alcohol, oleyl alcohol, stearyl alcohol, long chain branched aliphatic alcohols, cholesterol, phytosterols Sterols and derivatives such as branched fatty acid cholesterol ester, macadamia nut fatty acid phytosteryl ester, Processing oils such as chemical oils, stearic acid, myristic acid, iso-type long chain fatty acids, higher fatty acids such as anteiso-type long chain fatty acids, ethers such as dicapryl ether, limonene, terpenes such as hydrogenated bisabolol, sodium cetyl sulfate, Anionic surfactants such as N-stearoyl-L-glutamate, polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyoxyethylene polyhydric alcohol fatty acid ester, polyoxyethylene hydrogenated castor oil, polyhydric alcohol fatty acid ester, Nonionic surfactants such as polyglycerin fatty acid ester, modified silicon and sucrose ester, cationic surfactants such as tetraalkylammonium salt, amphoteric surfactants such as betaine type, sulfobetaine type, sulfoamino acid type, lecithin, Natural surfactants such as zophosphatidylcholine, ceramide, cerebroside, pigments such as titanium oxide and zinc oxide, antioxidants such as dibutylhydroxytoluene, inorganic salts such as sodium chloride, magnesium chloride, sodium sulfate, potassium nitrate, Organic acid salts such as sodium citrate, potassium acetate, sodium oxalate, sodium aspartate, sodium lactate, salts such as ethanolamine hydrochloride, ammonium nitrate, arginine hydrochloride, chelating agents such as edetic acid, potassium hydroxide, diisopropanolamine, Neutralizing agents such as triethanolamine, biopolymers such as hyaluronic acid and collagen, placental extracts, UV absorbers such as hydroxymethoxybenzophenone sulfonate, retinol, retinol acetate, retinol Vitamin A such as luminate and its derivatives, α-tocopherol, γ-tocopherol, δ-tocopherol, tocopherol nicotinate, tocopherol acetate and the like, and oils such as ascorbyl palmitate, ascorbyl stearate, ascorbyl tetraisostearate Polysaccharides extracted from soluble vitamin C derivatives, xanthan gum, β-glucan, oats, white jellyfish, etc.,
Extracted from seaweed such as carrageenan, alginic acid, agar, etc., water-soluble polymers such as carboxyvinyl polymer, pectin, alkyl-modified carboxyvinyl polymer, dipropylene glycol, 1,3-butylene glycol, glycerin, propylene glycol, Polyhydric alcohols such as sorbitol, malbitol, diglycerin, raffinose, and hexylene glycol can be arbitrarily blended.

Hereinafter, the present invention will be described in detail based on Examples and Comparative Examples.
First, a sensory test and a stability test using the emulsified cosmetics of Examples and Comparative Examples will be described.

[Sensory test]
Samples were applied to the faces of 30 adult women, and the number of people who did not feel oily feeling after application was shown.
[Stability test]
Immediately after the preparation, yellow crystals were observed to be precipitated or separated.

Examples 1 to 3, Comparative Examples 1 to 3 (beauty liquid)
A serum was prepared with the composition shown in Table 1, and the test was conducted.

(1) Preparation method Each component is mixed and stirred at room temperature.

(2) Characteristics Table 1 shows the observation results and sensory test results immediately after the preparation of Examples and Comparative Examples. As shown in Table 1, the cosmetic liquid of the examples of the present invention is superior to the cosmetic liquid of the comparative example using ester oil, squalane, silicone oil as the oil agent, and precipitation, separation, etc. of yellow crystals are not seen and excellent. Showed stability.

Example 4, Comparative Examples 4-9 (Cosmetic liquid)
A serum was prepared with the composition shown in Table 2, and the test was conducted.

(1) Preparation Method After each component is uniformly dissolved at room temperature, it is mixed and stirred and dispersed.

(2) Characteristics Table 2 shows the observation results and sensory test results immediately after the preparation of the examples and comparative examples. As shown in Table 2, the cosmetic liquids of the examples of the present invention, unlike the cosmetic liquids of the comparative examples using triglycerides and vegetable oils as oil agents, showed no precipitation, separation, etc. of yellow crystals, and excellent stability. Indicated.

Examples 5 to 7 (anti-aging serum)
Anti-aging serum was prepared with the composition shown in Table 3, and the above test was performed.

(1) Preparation Method Each component of the oil phase and the aqueous phase was dissolved at 80 ° C. and then cooled to 30 ° C. while mixing and stirring to prepare a cosmetic liquid.

(2) Characteristics Table 3 shows the results of the above tests. As shown in Table 3, the emulsified cosmetic of the present invention showed excellent storage stability.

Examples 8 to 10 (whitening serum)
A whitening serum was prepared with the composition shown in Table 4, and the test was conducted.

(1) Preparation Method Each component of the oil phase and the aqueous phase was dissolved at 60 ° C., and then mixed and stirred to prepare a cosmetic liquid.

(2) Characteristics Table 4 shows the results of the above test. As shown in Table 4, the emulsified cosmetic of the present invention showed excellent storage stability.

Examples 11-13 (moisturizing cream)
Moisturizing creams were prepared with the compositions described in Table 5 and the above tests were performed.

(1) Preparation Method Each component of the oil phase and the aqueous phase was dissolved at 80 ° C., and then mixed and stirred to prepare a cream.

(2) Characteristics Table 5 shows the results of the above tests. As shown in Table 5, the emulsified cosmetic of the present invention showed excellent storage stability.

Examples 14 to 16 (sunscreen)
Sunscreens were prepared with the compositions listed in Table 6 and the above tests were performed.

(1) Preparation Method Each component of the oil phase and the aqueous phase was dissolved at 80 ° C. and then mixed and stirred to prepare a sunscreen.

(2) Characteristics Table 6 shows the results of the above test. As shown in Table 6, the emulsified cosmetic of the present invention showed excellent storage stability.

Claims (2)

(A) and coenzyme Q10, characterized in that it contains the (B) and the water-soluble physiologically active substance, (C) dioctyl carbonate, carbonate dicapryl, one or more oils selected et or methylphenyl polysiloxanylalkyl down Emulsified cosmetic. (B) a water-soluble physiologically active substance is a mitochondrial activator selected from carnitine salt, γ-aminobutyric acid, lipoic acid, yeast extract, or arnica, aloe, altea, ashitaba, acerola, apricot, almond, amateur, akebi, Anise, Avocado, Dinosaur, Nettle, Strawberry, Fennel, Turmeric, Prickly Pear, Oolong Tea, Usbuni Oyster, Ages, Echinacea, Oat, Emperor, Edelweiss, Dutch Mustard, Oat, Ogon, Auren, Hypericum, Oca Valerian, persimmon, fire spine, chamomile, carrot, arabesque, oats, licorice, cucumber, kiwi, kina, kiraya, kizuta, gabba tea, mallet, clara, kumazasa, mulberry, walnut, grapefruit, gennosi Uko, Gentiana, Geto, Burdock, Comfrey, Wheat germ, Salvia, Hawthorn, Saishin, Saitai, Sanshi, Shimotsueso, Juyaku, Shichigenge, Shobu, Ginger, Shikon, Perilla, Birch, Peonies, Giant, Seekers, Simon, Sugina, Star fruit, mallow, cucumber, hawthorn, pheasant, sage, sea bream, soybeans, daidai, thyme, tachibanana, papaver, tamarind, tea, clove, chimpi, strawberry, dokudami, touki, tonin, spruce, tomato, dokudami, Tokisenka, wisteria tea, tormentilla, corn, green tea, elderberry, garlic, carrot, wild rose, papuamesu, hibiscus, parsley, banana, rose, pearl barley, green wheat, pecan nuts, Cypress, Hyssop, Sandalwood, Loquat, Prunes, Grapes, Fusazaki Sesen, Fusafujitsugi, Futomomo, Peppermint, Safflower, Loofah, Psyllium, White Genepi, Japanese cypress, Bodhi tree, Button boo, Button, Hop, Quince, Maikaika, Maroni Pine, Tangerine, Mulberry, Melissa, Peach, Cornflower, Saxifrage, Eucalyptus, Lily, Salmon, Yokuinin, Artemisia, Orchid, Lime, Lavender, Lettuce, Apple, Ryukyu Artemisia, Rooibos, Astragalus, Lemon, Lemon Balm, Rosehip, Rose Water and / or water-soluble organic solvent extract of plants, seaweed or fungus bodies selected from marie, green algae, red algae, brown algae, shiitake mushrooms, mushrooms, Sarno mushrooms, white jellyfish, litchi, cordyceps, lactic acid bacteria culture solution, yeast culture Emulsified cosmetic of claim 1, wherein the at least one selected from the liquid.