JP4062551B2 - ヒトケルベロスタンパク質 - Google Patents

ヒトケルベロスタンパク質 Download PDF

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Publication number
JP4062551B2
JP4062551B2 JP54698998A JP54698998A JP4062551B2 JP 4062551 B2 JP4062551 B2 JP 4062551B2 JP 54698998 A JP54698998 A JP 54698998A JP 54698998 A JP54698998 A JP 54698998A JP 4062551 B2 JP4062551 B2 JP 4062551B2
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JP
Japan
Prior art keywords
human
kerberos
protein
cell
binding
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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JP54698998A
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English (en)
Japanese (ja)
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JP2001526535A (ja
JP2001526535A5 (OSRAM
Inventor
エム. バレンズエラ,デイビッド
エイ. ロジャス,エドゥアルド
エヌ. エコノミデス,アリス
イー. スタール,ニール
Original Assignee
リジェネロン ファーマシューティカルズ,インコーポレイテッド
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26721541&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP4062551(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by リジェネロン ファーマシューティカルズ,インコーポレイテッド filed Critical リジェネロン ファーマシューティカルズ,インコーポレイテッド
Publication of JP2001526535A publication Critical patent/JP2001526535A/ja
Publication of JP2001526535A5 publication Critical patent/JP2001526535A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP54698998A 1997-04-29 1998-03-31 ヒトケルベロスタンパク質 Expired - Lifetime JP4062551B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4442797P 1997-04-29 1997-04-29
US60/044,427 1997-04-29
US4515797P 1997-04-30 1997-04-30
US60/045,157 1997-04-30
PCT/US1998/006324 WO1998049296A1 (en) 1997-04-29 1998-03-31 Human cerberus protein

Publications (3)

Publication Number Publication Date
JP2001526535A JP2001526535A (ja) 2001-12-18
JP2001526535A5 JP2001526535A5 (OSRAM) 2005-11-24
JP4062551B2 true JP4062551B2 (ja) 2008-03-19

Family

ID=26721541

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54698998A Expired - Lifetime JP4062551B2 (ja) 1997-04-29 1998-03-31 ヒトケルベロスタンパク質

Country Status (8)

Country Link
US (2) US6610510B1 (OSRAM)
EP (1) EP0975752A1 (OSRAM)
JP (1) JP4062551B2 (OSRAM)
AU (1) AU726385B2 (OSRAM)
CA (1) CA2288373C (OSRAM)
IL (1) IL132443A0 (OSRAM)
NZ (1) NZ500577A (OSRAM)
WO (1) WO1998049296A1 (OSRAM)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
DE69434651T2 (de) 1993-12-07 2007-03-08 Genetics Institute, Inc., Cambridge Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
WO1999061044A1 (en) * 1998-05-28 1999-12-02 The Board Of Trustees Of The University Of Arkansas Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption
JP4813660B2 (ja) * 1998-11-27 2011-11-09 ダーウィン ディスカバリー リミテッド 骨鉱化作用を増加するための組成物および方法
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
ATE271886T1 (de) 1999-10-15 2004-08-15 Inst Genetics Llc Hyaluronsäure enthaltende zusammensetzungen zur abgabe osteogener proteine
WO2002099037A2 (en) 2001-06-01 2002-12-12 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
SG143977A1 (en) * 2001-06-05 2008-07-29 Auckland Uniservices Ltd Methods and compositions for assessment of pulmonary function and disorders
CN1538850A (zh) * 2001-06-08 2004-10-20 ʷ 用于骨或软骨再生的bmp结合蛋白
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
GB2385052A (en) 2002-02-05 2003-08-13 Leuven K U Res & Dev Treatment of spondyloarthropathies
US7193069B2 (en) * 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA
US20060276385A1 (en) * 2003-01-13 2006-12-07 Hanjoong Jo Anti-inflammatory agents and methods of their use
US9045553B2 (en) 2004-05-27 2015-06-02 Acceleron Pharma, Inc. Cerberus/Coco derivatives and uses thereof
US7316998B2 (en) * 2004-05-27 2008-01-08 Acceleron Pharma Inc. Cerberus/Coco derivatives and uses thereof
US20060269946A1 (en) * 2005-05-10 2006-11-30 Young Robert P Methods and compositions for assessment of pulmonary function and disorders
AU2006248201A1 (en) * 2005-05-19 2006-11-23 Synergenz Bioscience Limited Methods for the assesssment of risk of developing lung cancer using analysis of genetic polymorphisms
JP2008545389A (ja) * 2005-05-19 2008-12-18 シナージェンズ バイオサイエンス リミティド 肺機能及び肺障害の評価のための方法及び組成物
EP1888779A4 (en) * 2005-05-20 2009-06-10 Synergenz Bioscience Ltd METHOD FOR THE ANALYSIS OF POLYMORPHISMS AND USES THEREOF
AU2007257208B2 (en) * 2006-05-17 2013-05-02 Stryker Corporation Use of a soluble morphogenic protein complex for treating cartilage defects
CA2671983A1 (en) 2006-12-08 2009-06-19 Acceleron Pharma Inc. Uses of cerberus, coco and derivatives thereof
CN105759056B (zh) * 2016-04-06 2017-11-14 四川大学华西医院 一种肺癌筛查试剂盒
US10961305B2 (en) 2016-12-21 2021-03-30 Mereo Biopharma 3 Limited Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952499A (en) * 1988-02-11 1990-08-28 Dana-Farber Cancer Institute Genes and their encoded proteins which regulate gene expression of the interleukin-2 receptor and of human lymphotropic retroviruses
US6133232A (en) * 1996-06-20 2000-10-17 The Regents Of The University Of California Endoderm, cardiac and neural inducing factors

Also Published As

Publication number Publication date
AU6873698A (en) 1998-11-24
NZ500577A (en) 2001-02-23
US6610510B1 (en) 2003-08-26
JP2001526535A (ja) 2001-12-18
CA2288373C (en) 2010-06-01
CA2288373A1 (en) 1998-11-05
AU726385B2 (en) 2000-11-02
EP0975752A1 (en) 2000-02-02
IL132443A0 (en) 2001-03-19
US7241739B2 (en) 2007-07-10
US20030199042A1 (en) 2003-10-23
WO1998049296A1 (en) 1998-11-05

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