JP4017669B2 - 光学活性アミンのラセミ化法 - Google Patents

光学活性アミンのラセミ化法 Download PDF

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Publication number
JP4017669B2
JP4017669B2 JP53425997A JP53425997A JP4017669B2 JP 4017669 B2 JP4017669 B2 JP 4017669B2 JP 53425997 A JP53425997 A JP 53425997A JP 53425997 A JP53425997 A JP 53425997A JP 4017669 B2 JP4017669 B2 JP 4017669B2
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JP
Japan
Prior art keywords
group
substituted
sodium
alkyl group
complex
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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JP53425997A
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English (en)
Japanese (ja)
Inventor
井上　　徹
吉彦 平山
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Nagase and Co Ltd
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Nagase and Co Ltd
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Publication of JP4017669B2 publication Critical patent/JP4017669B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
JP53425997A 1996-03-28 1997-03-27 光学活性アミンのラセミ化法 Expired - Lifetime JP4017669B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7375896 1996-03-28
PCT/JP1997/001058 WO1997035833A1 (fr) 1996-03-28 1997-03-27 Procede de racemisation d'amines actifs sur le plan optique

Publications (1)

Publication Number Publication Date
JP4017669B2 true JP4017669B2 (ja) 2007-12-05

Family

ID=13527463

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53425997A Expired - Lifetime JP4017669B2 (ja) 1996-03-28 1997-03-27 光学活性アミンのラセミ化法

Country Status (5)

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US (1) US5969186A (US07943777-20110517-C00090.png)
EP (1) EP0900780A4 (US07943777-20110517-C00090.png)
JP (1) JP4017669B2 (US07943777-20110517-C00090.png)
IN (1) IN186804B (US07943777-20110517-C00090.png)
WO (1) WO1997035833A1 (US07943777-20110517-C00090.png)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004004135A1 (de) 2004-01-28 2005-09-29 Alstom Technology Ltd Fördervorrichtung
EP2364977A1 (en) 2010-01-26 2011-09-14 Reuter Chemische Apparatebau KG Process for the enantiomeric enrichment of 3-methyl-1-(2-piperidinophenyl)-1-butylamine
EP3022183A1 (en) * 2013-07-19 2016-05-25 LEK Pharmaceuticals d.d. Method of racemisation of undesired enantiomers

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5735700B2 (US07943777-20110517-C00090.png) * 1973-08-31 1982-07-30
JPS5735701B2 (US07943777-20110517-C00090.png) * 1973-09-07 1982-07-30
CA1041114A (en) * 1973-09-07 1978-10-24 Tsuneyuki Nagase Racemization of optically active amines
JPS5735702B2 (US07943777-20110517-C00090.png) * 1973-09-07 1982-07-30
DE2348801A1 (de) * 1973-09-28 1975-04-10 Dynamit Nobel Ag Verfahren zur racemisierung von optisch aktivem 1-phenylaethylamin
JPS61172846A (ja) * 1985-01-29 1986-08-04 Hiroyuki Nohira （±）−２−クロロプロピオン酸の光学分割法
EP0253571B1 (en) * 1986-07-14 1989-08-23 Merck & Co. Inc. Process for resolution and race mization of amines with acidic alpha-hydrogens
US4859771A (en) * 1986-07-14 1989-08-22 Merck & Co., Inc. Process for resolution and racemization of amines with acidic α-hydrogens
JPH0780823B2 (ja) * 1986-08-26 1995-08-30 東ソー株式会社 光学活性フェニルアラニンのラセミ化方法
JPS63185943A (ja) * 1987-01-27 1988-08-01 Kanegafuchi Chem Ind Co Ltd 光学活性アミンのラセミ化法
JP3252579B2 (ja) * 1993-12-28 2002-02-04 東レ株式会社 光学活性１−（ハロゲノフェニル）エチルアミン類のラセミ化法
JPH07303496A (ja) * 1994-03-16 1995-11-21 Asahi Chem Ind Co Ltd 光学活性（ｓ）−２−フェニル−３−メチルブチルアミンの製造方法
JPH08151344A (ja) * 1994-09-26 1996-06-11 Nagase & Co Ltd ２−（３−ベンゾイルフェニル）プロピオン酸の光学分割方法
JPH0956396A (ja) * 1995-08-24 1997-03-04 Nagase & Co Ltd 光学活性３−メチル−２−フェニルブチルアミンの製法
JP3843474B2 (ja) * 1995-12-07 2006-11-08 住友化学株式会社 光学活性な１−フェニルエチルアミン誘導体のラセミ化方法

Also Published As

Publication number Publication date
WO1997035833A1 (fr) 1997-10-02
IN186804B (US07943777-20110517-C00090.png) 2001-11-10
US5969186A (en) 1999-10-19
EP0900780A4 (en) 2000-07-05
EP0900780A1 (en) 1999-03-10

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