JP4016070B2 - （１１β，１６β）―２１―（アセチルオキシ）―１１―ヒドロキシ―２’―メチル―５’Ｈ―プレグナ―１，４―ジエノ［１７，１６―Ｄ］オキサゾール―３，２０―ジオンの製造 - Google Patents

（１１β，１６β）―２１―（アセチルオキシ）―１１―ヒドロキシ―２’―メチル―５’Ｈ―プレグナ―１，４―ジエノ［１７，１６―Ｄ］オキサゾール―３，２０―ジオンの製造 Download PDF

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Publication number
JP4016070B2
JP4016070B2 JP52169797A JP52169797A JP4016070B2 JP 4016070 B2 JP4016070 B2 JP 4016070B2 JP 52169797 A JP52169797 A JP 52169797A JP 52169797 A JP52169797 A JP 52169797A JP 4016070 B2 JP4016070 B2 JP 4016070B2
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JP
Japan
Prior art keywords
formula
compound
process according
methyl
dione
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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JP52169797A
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English (en)
Japanese (ja)
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JP2000503632A (ja
Inventor
フオルテ，ルイジ
カンチエリエリ，カロジエロ
Original Assignee
サノフイ−アベンテイス・エツセ・ピー・アー
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Publication of JP2000503632A publication Critical patent/JP2000503632A/ja
Application granted granted Critical
Publication of JP4016070B2 publication Critical patent/JP4016070B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0057—Nitrogen and oxygen
    • C07J71/0068—Nitrogen and oxygen at position 16(17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
JP52169797A 1995-12-13 1996-12-04 （１１β，１６β）―２１―（アセチルオキシ）―１１―ヒドロキシ―２’―メチル―５’Ｈ―プレグナ―１，４―ジエノ［１７，１６―Ｄ］オキサゾール―３，２０―ジオンの製造 Expired - Lifetime JP4016070B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP95119626.0 1995-12-13
EP95119626 1995-12-13
PCT/EP1996/005390 WO1997021722A1 (en) 1995-12-13 1996-12-04 PREPARATION OF (11β,16β)-21-(ACETYLOXY)-11-HYDROXY-2'-METHYL-5'H-PREGNA-1,4-DIENO[17,16-D]OXAZOLE-3,20-DIONE

Publications (2)

Publication Number Publication Date
JP2000503632A JP2000503632A (ja) 2000-03-28
JP4016070B2 true JP4016070B2 (ja) 2007-12-05

Family

ID=8219882

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52169797A Expired - Lifetime JP4016070B2 (ja) 1995-12-13 1996-12-04 （１１β，１６β）―２１―（アセチルオキシ）―１１―ヒドロキシ―２’―メチル―５’Ｈ―プレグナ―１，４―ジエノ［１７，１６―Ｄ］オキサゾール―３，２０―ジオンの製造

Country Status (16)

Country Link
US (1) US6103895A (zh)
EP (1) EP0876394B1 (zh)
JP (1) JP4016070B2 (zh)
KR (1) KR100453029B1 (zh)
CN (1) CN100358914C (zh)
AT (1) ATE201213T1 (zh)
AU (1) AU707409B2 (zh)
CA (1) CA2238691C (zh)
DE (1) DE69612871T2 (zh)
DK (1) DK0876394T3 (zh)
ES (1) ES2157476T3 (zh)
GR (1) GR3035988T3 (zh)
HK (1) HK1017691A1 (zh)
PT (1) PT876394E (zh)
WO (1) WO1997021722A1 (zh)
ZA (1) ZA9610412B (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100351266C (zh) * 1995-12-13 2007-11-28 赛诺菲·阿温提斯股份公司 (11β，16β)－21－(3－羰基－3－氧代丙氧基) －11－羟基－2′－甲基－5′H－孕甾－1，4－二烯并[17，16－D]唑－3，20－二酮的制备方法
CN106008660B (zh) * 2016-06-20 2018-02-23 湖南科瑞生物制药股份有限公司 地夫可特的制备方法
CN107488203B (zh) * 2017-08-30 2019-06-04 湖南科瑞生物制药股份有限公司 一种16a-羟基泼尼松龙的制备方法
EP4230196A1 (en) 2022-02-21 2023-08-23 Som Innovation Biotech, S.A. Compounds for use in the treatment of dystrophinopathies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE250538C (zh) *
DD250538A1 (de) * 1984-12-11 1987-10-14 Jenapharm Veb Verfahren zur selektiven acetylierung von hydroxy-steroidcarbonsaeuren
GB8730216D0 (en) * 1987-12-29 1988-02-03 Lepetit Spa Process for preparation of pregnenooxazolines
CN100351266C (zh) * 1995-12-13 2007-11-28 赛诺菲·阿温提斯股份公司 (11β，16β)－21－(3－羰基－3－氧代丙氧基) －11－羟基－2′－甲基－5′H－孕甾－1，4－二烯并[17，16－D]唑－3，20－二酮的制备方法

Also Published As

Publication number Publication date
DE69612871D1 (de) 2001-06-21
EP0876394B1 (en) 2001-05-16
WO1997021722A1 (en) 1997-06-19
KR100453029B1 (ko) 2004-12-17
AU1175697A (en) 1997-07-03
AU707409B2 (en) 1999-07-08
CN100358914C (zh) 2008-01-02
ES2157476T3 (es) 2001-08-16
PT876394E (pt) 2001-08-30
HK1017691A1 (en) 1999-11-26
ATE201213T1 (de) 2001-06-15
US6103895A (en) 2000-08-15
GR3035988T3 (en) 2001-08-31
EP0876394A1 (en) 1998-11-11
ZA9610412B (en) 1997-07-23
DE69612871T2 (de) 2001-10-04
KR19990072026A (ko) 1999-09-27
DK0876394T3 (da) 2001-08-06
JP2000503632A (ja) 2000-03-28
CA2238691A1 (en) 1997-06-19
CA2238691C (en) 2004-07-20
CN1204339A (zh) 1999-01-06

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