JP4004213B2 - Whitening cosmetics - Google Patents

Description

【００２０】
実施例１〜実施例３及び比較例１について、色素沈着症状の改善効果を評価した。色素沈着症状の改善効果は、顕著なシミ，ソバカス等の色素沈着症状を有する女性パネラー２０名を一群とし、各群に実施例１〜実施例３及び比較例１をそれぞれブラインドにて１日２回ずつ１ヶ月間使用させ、１ヶ月後の皮膚の色素沈着の状態を観察して使用前と比較して評価した。色素沈着の状態は、表２に示す判定基準に従って評価し、２０名の平均値を算出して表３に示した。
【００２１】
【表２】

【００２２】
【表３】

【００２３】
表３において明らかなように、各種モウセンゴケ属植物抽出物を配合した実施例１〜実施例３使用群では、使用試験終了後の色素沈着症状は軽度と評価される程度にまで改善され、明確な色素沈着症状の改善が認められていた。これに対し、各種モウセンゴケ属植物抽出物を精製水に代替した比較例１使用群では色素沈着症状の改善は認められなかった。
【００２４】
なお、上記の使用期間において、いずれの実施例を使用した群においても、痛み，痒み等の皮膚刺激感やアレルギー反応などの皮膚症状を訴えたパネラーはいなかった。また乳化状態の悪化や配合成分の沈降，変質なども認められなかった。
【００２５】
［実施例４］皮膚用ローション
(１)エタノール １０．０(重量％)
(２)ヒドロキシエチルセルロース １．０
(３)モウセンゴケ抽出物１ ０．５
(４)コモウセンゴケ抽出物 ０．５
(５)グリセリン ７．０
(６)グアイアズレンスルホン酸ナトリウム ０．５
(７)精製水 ８０．５
製法：(１)〜(７)を混合し、均一とする。
【００２６】
［実施例５］皮膚用乳剤
(１)ステアリン酸 ０．２(重量％)
(２)セタノール １．５
(３)ワセリン ３．０
(４)流動パラフィン ７．０
(５)ポリオキシエチレン(10EO)モノオレイン酸エステル １．５
(６)乳酸菌抽出物 ０．５
(７)グリセリン ５．０
(８)トリエタノールアミン １．０
(９)モウセンゴケ抽出物２ １．０
(10)精製水 ７９．３
製法：(１)〜(６)の油相成分を混合，加熱して均一に溶解し、７０℃に保つ。一方、(７)〜(10)の水相成分を混合，加熱して均一とし、７０℃とする。この水相成分に油相成分を撹拌しながら徐々に添加して乳化する。
【００２７】
［実施例６］皮膚用ゲル剤
(１)精製水 ９０．９(重量％)
(２)カルボキシビニルポリマー ０．５
(３)コモウセンゴケ抽出物 ０．５
(４)ジプロピレングリコール ８．０
(５)水酸化カリウム ０．１
製法：(１)に(２)及び(３)を均一に溶解した後、(４)を添加し、次いで(５)を加えて増粘させる。
【００２８】
［実施例７］皮膚用クリーム
(１)ミツロウ ６．０(重量％)
(２)セタノール ５．０
(３)還元ラノリン ８．０
(４)スクワラン ２９．５
(５)親油型グリセリルモノステアリン酸エステル ４．０
(６)ポリオキシエチレン(20EO)
ソルビタンモノラウリン酸エステル ５．０
(７)プロピレングリコール ５．０
(８)モウセンゴケ抽出物１ １．０
(９)精製水 ３６．５
製法：(１)〜(６)の油相成分を混合，溶解して７５℃に加熱する。一方、(７)〜(９)の水相成分を混合，溶解して７５℃に加熱する。次いで、上記水相成分に油相成分を添加して予備乳化した後、ホモミキサーにて均一に乳化する。
【００２９】
［実施例８］水中油型乳剤性軟膏
(１)白色ワセリン ２５．０(重量％)
(２)ステアリルアルコール ２５．０
(３)グリセリン １０．０
(４)ラウリル硫酸ナトリウム １．０
(５)モウセンゴケ抽出物２ １．０
(６)精製水 ３８．０
製法：(１)〜(４)の油相成分を混合，溶解して均一とし、７５℃に加熱する。一方、(５)を(６)に溶解して７５℃にて加熱溶解し、これに前記油相成分を添加して乳化する。
【００３０】
［実施例９］化粧水
(１)エタノール １０．０(重量％)
(２)1,3-ブチレングリコール １０．０
(３)コモウセンゴケ抽出物 ０．５
(４)グリチルリチン酸ジカリウム ０．５
(５)香料 ０．１
(６)精製水 ７８．９
製法：(１)〜(５)を順次(６)に添加して均一に混合，溶解する。
【００３１】
［実施例１０］メイクアップベースクリーム
(１)ステアリン酸 １２．０(重量％)
(２)セタノール ２．０
(３)グリセリルトリ-2-エチルヘキサン酸エステル ２．５
(４)自己乳化型グリセリルモノステアリン酸エステル ２．０
(５)プロピレングリコール １０．０
(６)水酸化カリウム ０．３
(７)モウセンゴケ抽出物１ １．０
(８)精製水 ６８．６
(９)酸化チタン １．０
(10)ベンガラ ０．１
(11)黄酸化鉄 ０．４
(12)香料 ０．１
製法：(１)〜(４)の油相成分を混合し、７５℃に加熱して均一とする。一方、(５)〜(８)の成分を混合し、７５℃に加熱，溶解して均一とし、これに(９)〜(11)の顔料を添加し、ホモミキサーにて均一に分散させ水相成分とする。この水相成分に前記油相成分を添加し、ホモミキサーにて乳化した後冷却し、４０℃にて(12)の成分を添加，混合する。
【００３２】
［実施例１１］乳液状ファンデーション
(１)ステアリン酸 ２．０(重量％)
(２)スクワラン ５．０
(３)ミリスチン酸オクチルドデシル ５．０
(４)セタノール １．０
(５)デカグリセリルモノイソパルミチン酸エステル ９．０
(６)1,3-ブチレングリコール ８．０
(７)水酸化カリウム ０．１
(８)モウセンゴケ抽出物２ ０．８
(９)精製水 ５０．９
(10)酸化チタン ９．０
(11)タルク ７．４
(12)ベンガラ ０．５
(13)黄酸化鉄 １．１
(14)黒酸化鉄 ０．１
(15)香料 ０．１
製法：(１)〜(５)の油相成分を混合し、７５℃に加熱して均一とする。一方、(６)〜(９)の水相成分を混合し、７５℃に加熱，溶解して均一とし、これに(10)〜(14)の顔料を添加し、ホモミキサーにて均一に分散させる。油相成分を添加して乳化した後冷却し、４０℃にて(15)の成分を添加，混合する。
【００３３】
［実施例１２］ハンドクリーム
(１)セタノール ４．０(重量％)
(２)ワセリン ２．０
(３)流動パラフィン １０．０
(４)グリセリルモノステアリン酸エステル １．５
(５)ポリオキシエチレン(60EO)
グリセリルイソステアリン酸エステル ２．５
(６)酢酸トコフェロール ０．５
(７)グリセリン ２０．０
(８)パラオキシ安息香酸メチル ０．１
(９)コモウセンゴケ抽出物 １．０
(10)精製水 ５８．４
製法：(１)〜(６)の油相成分を混合，溶解して７５℃に加熱する。一方、(７)〜(10)の水相成分を混合，溶解して７５℃に加熱する。ついで、水相成分に油相成分を添加して予備乳化した後、ホモミキサーにて均一に乳化する。
【００３４】
［実施例１３］ゼリー状ピールオフパック
(１)ポリビニルアルコール １５．０(重量％)
(２)カルボキシメチルセルロース ５．０
(３)1,3-ブチレングリコール ３．０
(４)エタノール ６．０
(５)ポリオキシエチレン(20EO)オレイルエーテル ０．５
(６)モウセンゴケ抽出物１ ０．５
(７)精製水 ７０．０
製法：(７)に(３)を加えて７５℃に加熱する。これに(１)，(２)を添加して溶解させ、(４)〜(６)を添加して可溶化する。
【００３５】
［実施例１４］クレンジングジェル
(１)精製水 ６３．５(重量％)
(２)カルボキシビニルポリマー ０．５
(３)無水ケイ酸 ７．０
(４)モウセンゴケ抽出物２ １．０
(５)グリセリン １０．０
(６)1,3-ブチレングリコール ５．０
(７)ポリオキシエチレン(20EO)ラウリルエーテル ５．０
(８)ポリオキシエチレン(50EO)硬化ヒマシ油 ２．５
(９)ジエチレングリコールモノエチルエーテル ５．０
(10)水酸化カリウム ０．５
製法：(１)を７５℃に加熱し、(２)〜(10)の成分を順次添加して、混合均一化する。
【００３６】
［実施例１５］マッサージゲル
(１)ジプロピレングリコール ７．０(重量％)
(２)グリセリン ８．０
(３)ポリオキシエチレン(15EO)オレイルエーテル １．０
(４)カルボキシビニルポリマー ０．４
(５)メチルセルロース ０．２
(６)モウセンゴケ抽出物１ １．０
(７)水酸化カリウム ０．１
(８)精製水 ８２．３
製法：７５℃に加熱した(８)に、(１)〜(７)の成分を順次添加，溶解，均一化する。
【００３７】
［実施例１６］洗顔料
(１)ステアリン酸 ２．０(重量％)
(２)セタノール ３．０
(３)ワセリン １０．０
(４)流動パラフィン ３３．０
(５)ミリスチン酸イソプロピル ７．５
(６)グリセリルモノステアリン酸エステル ２．５
(７)ポリオキシエチレン(20EO)ソルビタン
モノステアリン酸エステル ２．５
(８)グリセリン ５．０
(９)モウセンゴケ抽出物２ １．０
(10)水酸化カリウム ０．１
(11)精製水 ３３．４
製法：(１)〜(７)の油相成分を混合，加熱溶解し、７０℃とする。一方、(８)〜(11)の水相成分を混合して加熱溶解し、７０℃とする。この水相成分に油相成分を徐々に添加して予備乳化し、次いでホモミキサーにて均一に乳化する。
【００３８】
本発明の実施例１〜１６について、皮膚刺激性及び保存安定性を調べた。皮膚刺激性は、男性パネラー２０名による４８時間の閉塞貼付試験を行い、その結果を表４に示す判定基準に従って判定し、２０名の皮膚刺激指数の平均値にて示した。なお実施例１３のゼリー状ピールオフパックは、塗布後２０分で皮膜を剥離した後閉塞して評価を行い、実施例１４のクレンジングジェル及び実施例１６の洗顔料は１重量％水溶液にて評価を行った。保存安定性は、４０℃恒温槽にて６ヶ月間保存し、分離，変色，変臭の有無を観察した。結果を表５に示す。
【００３９】
【表４】

【００４０】
【表５】

【００４１】
表５に示した通り、本発明の実施例は皮膚刺激性を示すことが無く安全性が良好で、しかも４０℃６ヶ月保存後に分離，変色，変臭も認められず、安定性も良好であることが示された。
【００４２】
【発明の効果】
以上詳述したように、本発明により、日焼けなどによるシミ，ソバカスに対する皮膚美白効果に優れ、安定性，安全性の良好な美白化粧料を得ることができた。[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a whitening cosmetic that has an excellent skin whitening effect on spots and freckles caused by sunburn.
[0002]
[Prior art]
Conventionally, whitening cosmetics have been of great interest for improving skin color blackness, spots, freckles, etc. In these, ascorbic acid, glutathione, colloidal sulfur and the like have been incorporated as active ingredients. . There are also examples using various medicinal plant extracts, plant-derived gallic acid, geraniin and the like. Research on the whitening effect of seaweed extract has also been actively conducted, and a melanin formation inhibitory substance (JP-A-1-224308) in a cosmetic liquid mixture comprising a brown algae extract, a melanogenesis inhibitory substance extracted from seaweed (JP-A-2 -88592), cosmetics containing a hydrophilic solvent extract of brown algae as a tyrosinase inhibitory active substance (Japanese Patent Laid-Open No. 2-124810), and a hydrophilic organic solvent extract of the red alga genus Tsunomata Whitening cosmetics (JP-A-4-95013) are disclosed. In addition, whitening components such as kojic acid and arbutin which is a glucopyranoside derivative have recently been used. Such whitening components include tyrosinase activity inhibitors that inhibit the activity of tyrosinase that catalyzes the production of melanin, melanin biosynthesis inhibitors that inhibit part or all of the process of producing melanin from tyrosine via dopa, dopaquinone, dopachrome, Melanin excretion promoters and the like that normalize melanin metabolism are known.
[0003]
[Problems to be solved by the invention]
However, ascorbic acid is easily oxidized and unstable, and glutathione and colloidal sulfur have the disadvantage that they produce a characteristic odor and precipitation. In addition, conventional medicinal plant extracts and seaweed extracts have problems that their effects are insufficient and the quality is not constant. Furthermore, it has been necessary to consider the maintenance of the stability of kojic acid and the like. In addition, side effects caused side effects.
[0004]
An object of the present invention is to solve such problems and to provide a whitening cosmetic composition that is excellent in melanin production inhibitory effect and that has high safety and stability.
[0005]
[Means for Solving the Problems]
Since whitening cosmetics are used continuously every day, it is desired that the active ingredients blended with them are mild in action, exhibit sufficient effects by continuous use, and have no side effects due to continuous use. Therefore, we screened plant extracts that have an effective and mild skin-whitening effect, as well as high stability and safety.
[0006]
As a result, a high melanin production inhibitory effect was found in an extract of one or more plants selected from the genus Droseraceae and Drosera L .. These plant extracts have no adverse effects on the skin such as skin irritation and skin sensitization, and when blended with whitening cosmetics, the melanin production inhibitory effect is not inactivated and the quality is stable. It was. The plant of the genus Mosengoke is a carnivorous plant that has a large number of glandular hairs on the surface of the leaf blades and sticks out small animals by sticking out mucus, and the whole plant has been used as expectorant, detoxification, and analgesic. As the use of the extract of the plant belonging to the genus Pleurotus genus, an anti-androgenic agent containing the extract of Pleurotus genus as an active ingredient and its use for cosmetics (Japanese Patent Laid-Open No. 11-180819) have already been disclosed.
[0007]
DETAILED DESCRIPTION OF THE INVENTION
As plant droseraceae used in the present invention (Droseraceae) Drosera (Drosera L.), Naga bar Roh Drosera (Drosera anglica Huds.), Drosera peltata (Drosera peltata Smith.), Drosera (Drosera rotundifolia L.), Komousengoke (Drosera spathulata Labill.), and among them, one or two selected from Drosera rotundifolia L. and Drosera spathulata Labill. are preferably used in terms of whitening effect.
[0008]
These extracts from the genus Drosera L. are used in various raw plants or in one or more places such as leaves, bark, roots, flowers, branches, fruits, etc., raw or dried. Among them, whole plant extracts are the most effective. The extraction solvent is not particularly limited, and monohydric alcohols such as water, ethanol, methanol, isopropanol, isobutanol, n-hexanol, methyl amyl alcohol, 2-ethyl butanol, n-octyl alcohol, glycerin, ethylene glycol, ethylene Polyols such as glycol monomethyl ether, propylene glycol, propylene glycol monomethyl ether, propylene glycol monoethyl ether, triethylene glycol, 1,3-butylene glycol, hexylene glycol or derivatives thereof, acetone, methyl ethyl ketone, methyl isobutyl ketone, methyl ketones such as -n-propyl ketone, esters such as ethyl acetate and isopropyl acetate, ethers such as ethyl ether, isopropyl ether and n-butyl ether , Hydrocarbons such as squalane, petrolatum, paraffin wax, paraffin oil, olive oil, wheat germ oil, rice oil, sesame oil, macadamian nut oil, almond oil, coconut oil and other vegetable oils, beef fat, pork fat, whale oil, etc. Animal fats and oils are exemplified. In addition, polar solvents to which inorganic salts such as phosphate buffered saline are added, and solvents to which surfactants are added can be used, and although not particularly limited, safety and effects when blended into whitening cosmetics Therefore, it is preferable to use one or more solvents selected from water, ethanol, and 1,3-butylene glycol.
[0009]
Furthermore, examples of the extraction method include a method of extraction by impregnation in a cooled or heated state at room temperature, a method of extraction using a distillation method such as steam distillation, a pressing method of squeezing a genus Pleurotus and obtaining an extract. These methods are used alone or in combination of two or more.
[0010]
The ratio of the genus Mosorghum plant and the solvent at the time of extraction is not particularly limited. Is preferred. The extraction pressure and extraction temperature are conveniently in the range from 0 ° C. to the boiling point of the solvent under normal pressure, and the extraction time is preferably in the range of 2 hours to 2 weeks, although it varies depending on the extraction temperature.
[0011]
As for the extract of the genus Pleurotus genus obtained in this way, the extract can be used as it is. However, as long as the effect is not lost, purification operations such as deodorization, decolorization and concentration are added, and further, column chromatography is performed. It may be used as a fraction using a graphic or the like. These extracts, purified products, and fractions can be dried by removing the solvent from them, and can be used in a form solubilized in a solvent such as alcohol, or in the form of an emulsion. it can.
[0012]
The blending amount of these melanogaster plant extracts having an inhibitory effect on melanin production into the whitening cosmetics is set to a concentration range of 0.0001 to 10% by weight in consideration of the effect, odor and color tone when added. It is desirable.
[0013]
In the whitening cosmetics of the present invention, oils and fats, moisturizers, powders, pigments, emulsifiers, solubilizers, washings, which are usually blended with pharmaceuticals, quasi-drugs, skin cosmetics and detergents as needed Agents, ultraviolet absorbers, thickeners, drugs, fragrances, resins, alcohols, and the like can be appropriately blended. The dosage form of the whitening cosmetic composition of the present invention is arbitrary, and can be provided as a solubilizing system such as lotion, an emulsifying system such as cream or emulsion, or a dispersing system such as calamine lotion, or a propellant. It is also possible to take aerosol dosage forms filled together.
[0014]
【Example】
Further, the features of the present invention will be described in detail by way of examples. First, the preparation example of the plant genus plant extract used by this invention is shown.
[0015]
[Mousengo extract 1]
550 g of the whole plant of Drosera rotundifolia L. was dried, pulverized, and extracted by stirring in 1,500 ml of 50% by volume ethanol aqueous solution at 25 ° C. for 5 days. Subsequently, the extract was filtered and the filtrate was referred to as Mosensoke extract 1.
[0016]
[Mousengo extract 2]
500 g of whole grass of Drosera rotundifolia L. was dried, pulverized, and extracted by stirring in 1,000 ml of 50 volume% 1,3-butylene glycol aqueous solution at 25 ° C. for 5 days. Next, the extract was filtered, and the filtrate was collected to obtain Moensen extract 2.
[0017]
[Compositon extract]
350 g of whole grass of Drosera spathulata Labill. Was cut into small pieces and extracted by immersion in 1,000 ml of 1,3-butylene glycol at 20 ° C. for 7 days. The extract was filtered, and the filtrate was collected to obtain a kumquat extract.
[0018]
[Examples 1 to 3, Comparative Example 1] O / W emulsified beauty solution
(1) Squalane 5.0 (% by weight)
(2) White petrolatum 2.0
(3) Beeswax 0.5
(4) Sorbitan sesquioleate 0.8
(5) Polyoxyethylene oleyl ether (20EO) 1.2
(6) Methyl paraoxybenzoate 0.1
(7) Propylene glycol 5.0
(8) Purified water 59.1
(9) Carboxyvinyl polymer 1.0 wt% aqueous solution 20.0
(10) Potassium hydroxide 0.1
(11) Ethanol 5.0
(12) Ingredients shown in Table 1 1.0
(13) Fragrance 0.2
Production method: The oil phase components (1) to (5) are mixed and heated to 75 ° C. to dissolve and homogenize. On the other hand, the water phase components (6) to (8) are mixed and dissolved, heated to 75 ° C., and the oil phase components are gradually added and pre-emulsified. After (9) is added, the mixture is uniformly emulsified with a homomixer, and (10) is added to adjust the pH. After cooling, add (11) to (13) at 40 ° C. and mix and homogenize.
[0019]
[Table 1]

[0020]
About Example 1- Example 3 and Comparative Example 1, the improvement effect of the pigmentation symptom was evaluated. The effect of improving the pigmentation symptom is a group of 20 female panelists having a pigmentation symptom such as remarkable spots and buckwheat, and each group is blinded with each of Examples 1 to 3 and Comparative Example 1 on a daily basis. Each time it was used for 1 month, the state of skin pigmentation after 1 month was observed and evaluated in comparison with before use. The pigmentation state was evaluated according to the criteria shown in Table 2, and the average value of 20 people was calculated and shown in Table 3.
[0021]
[Table 2]

[0022]
[Table 3]

[0023]
As is apparent from Table 3, in the use groups of Examples 1 to 3 in which various extracts of the genus Pleurotus genus were blended, the pigmentation symptom after the end of the use test was improved to such a degree that it was evaluated as mild and clear. Improvement of pigmentation symptoms was observed. On the other hand, the improvement of pigmentation symptoms was not observed in the group using Comparative Example 1 in which various plant species were replaced with purified water.
[0024]
In the above period of use, none of the groups using any of the examples complained of skin irritation such as pain and itching and skin symptoms such as allergic reactions. In addition, deterioration of the emulsified state and sedimentation and alteration of the blended components were not observed.
[0025]
[Example 4] Skin lotion
(1) Ethanol 10.0 (wt%)
(2) Hydroxyethyl cellulose 1.0
(3) Moensen extract 1 0.5
(4) Komodensoke extract 0.5
(5) Glycerin 7.0
(6) Sodium guaiazulene sulfonate 0.5
(7) Purified water 80.5
Production method: (1) to (7) are mixed and made uniform.
[0026]
[Example 5] Emulsion for skin
(1) Stearic acid 0.2 (% by weight)
(2) Cetanol 1.5
(3) Vaseline 3.0
(4) Liquid paraffin 7.0
(5) Polyoxyethylene (10EO) monooleate 1.5
(6) Lactic acid bacteria extract 0.5
(7) Glycerin 5.0
(8) Triethanolamine 1.0
(9) Moensen extract 2 1.0
(10) Purified water 79.3
Production method: The oil phase components (1) to (6) are mixed, heated and uniformly dissolved, and kept at 70 ° C. On the other hand, the aqueous phase components (7) to (10) are mixed and heated to be uniform, and set to 70 ° C. The oil phase component is gradually added to the aqueous phase component with stirring and emulsified.
[0027]
[Example 6] Gel for skin
(1) Purified water 90.9 (wt%)
(2) Carboxyvinyl polymer 0.5
(3) Komodensoke extract 0.5
(4) Dipropylene glycol 8.0
(5) Potassium hydroxide 0.1
Production method: (2) and (3) are uniformly dissolved in (1), then (4) is added, and then (5) is added to increase the viscosity.
[0028]
[Example 7] Cream for skin
(1) Beeswaw 6.0 (wt%)
(2) Cetanol 5.0
(3) Reduced lanolin 8.0
(4) Squalane 29.5
(5) Lipophilic glyceryl monostearate 4.0
(6) Polyoxyethylene (20EO)
Sorbitan monolaurate 5.0
(7) Propylene glycol 5.0
(8) Moensen extract 1 1.0
(9) Purified water 36.5
Production method: The oil phase components (1) to (6) are mixed, dissolved, and heated to 75 ° C. On the other hand, the aqueous phase components (7) to (9) are mixed and dissolved, and heated to 75 ° C. Subsequently, after adding an oil phase component to the said water phase component and pre-emulsifying, it emulsifies uniformly with a homomixer.
[0029]
[Example 8] Oil-in-water emulsion ointment
(1) White petrolatum 25.0 (wt%)
(2) Stearyl alcohol 25.0
(3) Glycerin 10.0
(4) Sodium lauryl sulfate 1.0
(5) Moensen extract 2 1.0
(6) Purified water 38.0
Production method: The oil phase components (1) to (4) are mixed, dissolved and made uniform, and heated to 75 ° C. On the other hand, (5) is dissolved in (6), heated and dissolved at 75 ° C., and the oil phase component is added thereto to emulsify.
[0030]
[Example 9] Lotion
(1) Ethanol 10.0 (wt%)
(2) 1,3-butylene glycol 10.0
(3) Komodensoke extract 0.5
(4) Dipotassium glycyrrhizinate 0.5
(5) Fragrance 0.1
(6) Purified water 78.9
Production method: (1) to (5) are sequentially added to (6) and uniformly mixed and dissolved.
[0031]
[Example 10] Makeup base cream
(1) Stearic acid 12.0 (wt%)
(2) Cetanol 2.0
(3) Glyceryl tri-2-ethylhexanoate 2.5
(4) Self-emulsifying glyceryl monostearate 2.0
(5) Propylene glycol 10.0
(6) Potassium hydroxide 0.3
(7) Moensen extract 1 1.0
(8) Purified water 68.6
(9) Titanium oxide 1.0
(10) Bengala 0.1
(11) Yellow iron oxide 0.4
(12) Fragrance 0.1
Production method: The oil phase components (1) to (4) are mixed and heated to 75 ° C. to be uniform. On the other hand, the components (5) to (8) are mixed, heated and dissolved at 75 ° C. to make it uniform, and the pigments (9) to (11) are added to this and dispersed uniformly with a homomixer. The phase component. The oil phase component is added to the water phase component, emulsified with a homomixer, cooled, and the component (12) is added and mixed at 40 ° C.
[0032]
[Example 11] Emulsion foundation
(1) Stearic acid 2.0 (wt%)
(2) Squalane 5.0
(3) Octyldodecyl myristate 5.0
(4) Cetanol 1.0
(5) Decaglyceryl monoisopalmitate 9.0
(6) 1,3-butylene glycol 8.0
(7) Potassium hydroxide 0.1
(8) Moensen extract 2 0.8
(9) Purified water 50.9
(10) Titanium oxide 9.0
(11) Talc 7.4
(12) Bengala 0.5
(13) Yellow iron oxide 1.1
(14) Black iron oxide 0.1
(15) Fragrance 0.1
Production method: The oil phase components (1) to (5) are mixed and heated to 75 ° C. to be uniform. On the other hand, the water phase components (6) to (9) are mixed, heated and dissolved at 75 ° C. to make it uniform, and the pigments (10) to (14) are added thereto and dispersed uniformly with a homomixer. Let The oil phase component is added and emulsified, then cooled, and the component (15) is added and mixed at 40 ° C.
[0033]
[Example 12] Hand cream
(1) Cetanol 4.0 (wt%)
(2) Vaseline 2.0
(3) Liquid paraffin 10.0
(4) Glyceryl monostearate ester 1.5
(5) Polyoxyethylene (60EO)
Glyceryl isostearate 2.5
(6) Tocopherol acetate 0.5
(7) Glycerin 20.0
(8) Methyl paraoxybenzoate 0.1
(9) Komodensoke extract 1.0
(10) Purified water 58.4
Production method: The oil phase components (1) to (6) are mixed, dissolved, and heated to 75 ° C. On the other hand, the aqueous phase components (7) to (10) are mixed and dissolved and heated to 75 ° C. Next, the oil phase component is added to the water phase component and pre-emulsified, and then uniformly emulsified with a homomixer.
[0034]
[Example 13] Jelly peel-off pack
(1) Polyvinyl alcohol 15.0 (% by weight)
(2) Carboxymethylcellulose 5.0
(3) 1,3-butylene glycol 3.0
(4) Ethanol 6.0
(5) Polyoxyethylene (20EO) oleyl ether 0.5
(6) Moensen extract 1 0.5
(7) Purified water 70.0
Production method: Add (3) to (7) and heat to 75 ° C. (1) and (2) are added and dissolved therein, and (4) to (6) are added and solubilized.
[0035]
[Example 14] Cleansing Gel
(1) Purified water 63.5 (wt%)
(2) Carboxyvinyl polymer 0.5
(3) Silicic anhydride 7.0
(4) Moensen extract 2 1.0
(5) Glycerin 10.0
(6) 1,3-butylene glycol 5.0
(7) Polyoxyethylene (20EO) lauryl ether 5.0
(8) Polyoxyethylene (50EO) hydrogenated castor oil 2.5
(9) Diethylene glycol monoethyl ether 5.0
(10) Potassium hydroxide 0.5
Production method: (1) is heated to 75 ° C., and the components (2) to (10) are sequentially added to mix and homogenize.
[0036]
[Example 15] Massage gel
(1) Dipropylene glycol 7.0 (% by weight)
(2) Glycerin 8.0
(3) Polyoxyethylene (15EO) oleyl ether 1.0
(4) Carboxyvinyl polymer 0.4
(5) Methylcellulose 0.2
(6) Moensen extract 1 1.0
(7) Potassium hydroxide 0.1
(8) Purified water 82.3
Production method: Components (1) to (7) are sequentially added, dissolved and homogenized to (8) heated to 75 ° C.
[0037]
[Example 16] Face wash
(1) Stearic acid 2.0 (wt%)
(2) Cetanol 3.0
(3) Vaseline 10.0
(4) Liquid paraffin 33.0
(5) Isopropyl myristate 7.5
(6) Glyceryl monostearate 2.5
(7) Polyoxyethylene (20EO) sorbitan monostearate 2.5
(8) Glycerin 5.0
(9) Moensen extract 2 1.0
(10) Potassium hydroxide 0.1
(11) Purified water 33.4
Production method: The oil phase components (1) to (7) are mixed and dissolved by heating to 70 ° C. On the other hand, the water phase components (8) to (11) are mixed and dissolved by heating to 70 ° C. The oil phase component is gradually added to this water phase component and pre-emulsified, and then uniformly emulsified with a homomixer.
[0038]
About Examples 1-16 of this invention, skin irritation and storage stability were investigated. For skin irritation, a 48-hour occlusion patch test was conducted by 20 male panelists, and the results were determined according to the criteria shown in Table 4 and indicated by the average value of the skin irritation index of 20 persons. In addition, the jelly-like peel-off pack of Example 13 was evaluated by clogging after peeling off the film 20 minutes after application, and the cleansing gel of Example 14 and the face wash of Example 16 were evaluated in a 1% by weight aqueous solution. went. The storage stability was stored for 6 months in a constant temperature bath at 40 ° C., and the presence or absence of separation, discoloration, and odor change was observed. The results are shown in Table 5.
[0039]
[Table 4]

[0040]
[Table 5]

[0041]
As shown in Table 5, the examples of the present invention do not show skin irritation and have good safety, and after storage at 40 ° C. for 6 months, separation, discoloration and odor are not observed, and stability is also good. It was shown that there is.
[0042]
【The invention's effect】
As described in detail above, according to the present invention, it was possible to obtain a whitening cosmetic composition that has an excellent skin whitening effect on spots and freckles due to sunburn and the like, and has excellent stability and safety.

Claims (1)

A whitening cosmetic containing an extract of the genus Mosengoke.