JP3996396B2 - 18fフッ化物の生産のためのシステムと方法 - Google Patents

18fフッ化物の生産のためのシステムと方法 Download PDF

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JP3996396B2
JP3996396B2 JP2001562717A JP2001562717A JP3996396B2 JP 3996396 B2 JP3996396 B2 JP 3996396B2 JP 2001562717 A JP2001562717 A JP 2001562717A JP 2001562717 A JP2001562717 A JP 2001562717A JP 3996396 B2 JP3996396 B2 JP 3996396B2
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fluoride
solvent
reaction chamber
separator
gas
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Japanese (ja)
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JP2003524787A5 (fr
JP2003524787A (ja
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トーマス・ジェイ・ルース
ケネス・アール・バックリー
チュン・クウォンソー
サルマ・ジバン
シュテファン・カー・ザイスラー
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Alberta University Of British Columbia carlton University simon Fraser University University Of Victoria doing Business Triumf AS, University of
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Alberta University Of British Columbia carlton University simon Fraser University University Of Victoria doing Business Triumf AS, University of
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    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21GCONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/04Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
    • G21G1/10Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by bombardment with electrically charged particles
    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21GCONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/001Recovery of specific isotopes from irradiated targets
    • G21G2001/0015Fluorine

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Glass Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Fertilizers (AREA)
  • Noodles (AREA)
  • Saccharide Compounds (AREA)
  • Physical Water Treatments (AREA)
JP2001562717A 2000-02-23 2001-02-23 18fフッ化物の生産のためのシステムと方法 Expired - Fee Related JP3996396B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18435200P 2000-02-23 2000-02-23
US60/184,352 2000-02-23
PCT/US2001/005608 WO2001063623A1 (fr) 2000-02-23 2001-02-23 Systeme et procede de production de fluorure 18f

Publications (3)

Publication Number Publication Date
JP2003524787A JP2003524787A (ja) 2003-08-19
JP2003524787A5 JP2003524787A5 (fr) 2005-08-04
JP3996396B2 true JP3996396B2 (ja) 2007-10-24

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JP2001562717A Expired - Fee Related JP3996396B2 (ja) 2000-02-23 2001-02-23 18fフッ化物の生産のためのシステムと方法

Country Status (9)

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US (2) US6845137B2 (fr)
EP (1) EP1258010B1 (fr)
JP (1) JP3996396B2 (fr)
AT (1) ATE430368T1 (fr)
AU (2) AU3981601A (fr)
CA (1) CA2401066C (fr)
DE (1) DE60138526D1 (fr)
MX (1) MXPA02008280A (fr)
WO (1) WO2001063623A1 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6599484B1 (en) * 2000-05-12 2003-07-29 Cti, Inc. Apparatus for processing radionuclides
AU2001274843A1 (en) * 2000-05-17 2001-11-26 The Regents Of The University Of California Method for producing(18f)fluoride ion
US6567492B2 (en) * 2001-06-11 2003-05-20 Eastern Isotopes, Inc. Process and apparatus for production of F-18 fluoride
JP3989897B2 (ja) * 2001-06-13 2007-10-10 ザ ユニバーシティ オブ アルバータ,ザ ユニバーシティ オブ ブリティッシュ コロンビア,カールトン ユニバーシティ,サイモン フレイザー ユニバーシティ アンド ザ ユニバーシティ オブ ビクトリ イオンビームによる18f−フッ化物の製造のための装置と方法
US7018614B2 (en) * 2002-11-05 2006-03-28 Eastern Isotopes, Inc. Stabilization of radiopharmaceuticals labeled with 18-F
US20050201505A1 (en) * 2003-08-08 2005-09-15 Welch Michael J. Enhanced separation process for (76Br, 77Br and 124I) preparation and recovery of each
US7831009B2 (en) * 2003-09-25 2010-11-09 Siemens Medical Solutions Usa, Inc. Tantalum water target body for production of radioisotopes
DE102005026253A1 (de) * 2004-06-18 2006-01-05 General Electric Co. Erzeugung von 18F(F2) Fluor aus 18O(O2) Sauerstoff mit hoher Ausbeute
US20050279130A1 (en) * 2004-06-18 2005-12-22 General Electric Company 18O[O2] oxygen refilling technique for the production of 18[F2] fluorine
US20060023829A1 (en) * 2004-08-02 2006-02-02 Battelle Memorial Institute Medical radioisotopes and methods for producing the same
US20060039522A1 (en) * 2004-08-18 2006-02-23 Research Foundation Of The State University Of New York Cyclotron target, apparatus for handling fluids with respect thereto and for recovering irradiated fluids, and methods of operating same
GB0506041D0 (en) * 2005-03-24 2005-04-27 Ge Healthcare Ltd Stripping method
GB2426862B (en) * 2005-06-04 2007-04-11 Alan Charles Sturt Thermonuclear power generation
JP4099187B2 (ja) * 2005-09-30 2008-06-11 株式会社日立製作所 放射性同位元素製造装置、及びターゲットのリサイクル方法
JP4885809B2 (ja) * 2007-08-14 2012-02-29 住友重機械工業株式会社 Oガス回収装置及びoガス回収方法
US20100243082A1 (en) * 2007-10-31 2010-09-30 Atomic Energy Council - Institute Of Nuclear Energy Research Liquid isotope delivery system
KR100967359B1 (ko) * 2008-04-30 2010-07-05 한국원자력연구원 내부 핀구조를 가지는 동위원소 생산 기체표적
KR20160072846A (ko) 2008-05-02 2016-06-23 샤인 메디컬 테크놀로지스, 인크. 의료용 동위원소를 생산하는 디바이스 및 방법
WO2012003009A2 (fr) 2010-01-28 2012-01-05 Shine Medical Technologies, Inc. Chambre de réaction segmentée pour production de radio-isotope
US9177679B2 (en) * 2010-02-11 2015-11-03 Uchicago Argonne, Llc Accelerator-based method of producing isotopes
US9336916B2 (en) 2010-05-14 2016-05-10 Tcnet, Llc Tc-99m produced by proton irradiation of a fluid target system
WO2012039036A1 (fr) * 2010-09-22 2012-03-29 独立行政法人放射線医学総合研究所 Processus et dispositif pour la production d'un radionucléide à l'aide d'un accélérateur
WO2012092394A1 (fr) 2010-12-29 2012-07-05 Cardinal Health 414, Llc Système fermé de remplissage de flacon pour distribution aseptique
US10734126B2 (en) 2011-04-28 2020-08-04 SHINE Medical Technologies, LLC Methods of separating medical isotopes from uranium solutions
US9269467B2 (en) 2011-06-02 2016-02-23 Nigel Raymond Stevenson General radioisotope production method employing PET-style target systems
US20130102772A1 (en) 2011-07-15 2013-04-25 Cardinal Health 414, Llc Systems, methods and devices for producing, manufacturing and control of radiopharmaceuticals-full
US9417332B2 (en) 2011-07-15 2016-08-16 Cardinal Health 414, Llc Radiopharmaceutical CZT sensor and apparatus
US20130020727A1 (en) 2011-07-15 2013-01-24 Cardinal Health 414, Llc. Modular cassette synthesis unit
CA2869559C (fr) 2012-04-05 2022-03-29 Shine Medical Technologies, Inc. Ensemble aqueux et methode de controle
US10849994B2 (en) * 2016-06-28 2020-12-01 Asociación Centro De Investigación Cooperativa En Biomateriales — Cic Biomagune Pharmaceutical composition comprising fluorine-18 labelled gases
JP6274689B1 (ja) * 2016-11-16 2018-02-07 株式会社京都メディカルテクノロジー Ri標識化合物製造装置及びri標識化合物製造方法
US10109383B1 (en) * 2017-08-15 2018-10-23 General Electric Company Target assembly and nuclide production system
JP6873381B1 (ja) * 2020-12-19 2021-05-19 株式会社京都メディカルテクノロジー 18f標識化合物製造装置及び18f標識化合物製造方法
CN113955771A (zh) * 2021-10-29 2022-01-21 北京善为正子医药技术有限公司 一种快速制备18f氟化钠pet药物的自动合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1201222A (fr) * 1982-06-01 1986-02-25 Robert Robertson Obtention d'iode-123 par la methode du gaz-cible
DE3424525A1 (de) 1984-07-04 1986-01-16 Kernforschungsanlage Jülich GmbH, 5170 Jülich Verfahren zur herstellung von (pfeil hoch)1(pfeil hoch)(pfeil hoch)8(pfeil hoch)f-alkyl- und arylverbindungen durch halogenaustausch
JPH0778558B2 (ja) * 1990-07-20 1995-08-23 日本鋼管株式会社 ▲上13▼nh▲上+▼▲下4▼,▲上18▼f−同時製造用ターゲット箱
US5280505A (en) * 1991-05-03 1994-01-18 Science Research Laboratory, Inc. Method and apparatus for generating isotopes
US5425063A (en) * 1993-04-05 1995-06-13 Associated Universities, Inc. Method for selective recovery of PET-usable quantities of [18 F] fluoride and [13 N] nitrate/nitrite from a single irradiation of low-enriched [18 O] water
US5468355A (en) * 1993-06-04 1995-11-21 Science Research Laboratory Method for producing radioisotopes
US5917874A (en) * 1998-01-20 1999-06-29 Brookhaven Science Associates Accelerator target

Also Published As

Publication number Publication date
EP1258010A1 (fr) 2002-11-20
DE60138526D1 (de) 2009-06-10
WO2001063623A1 (fr) 2001-08-30
AU2001239816B2 (en) 2005-01-27
JP2003524787A (ja) 2003-08-19
AU3981601A (en) 2001-09-03
US6845137B2 (en) 2005-01-18
US20010043663A1 (en) 2001-11-22
US20050129162A1 (en) 2005-06-16
EP1258010B1 (fr) 2009-04-29
ATE430368T1 (de) 2009-05-15
MXPA02008280A (es) 2004-04-05
CA2401066A1 (fr) 2001-08-30
CA2401066C (fr) 2010-08-10

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