JP3990889B2 - 質量分析装置およびこれを用いる計測システム - Google Patents

質量分析装置およびこれを用いる計測システム Download PDF

Info

Publication number
JP3990889B2
JP3990889B2 JP2001312118A JP2001312118A JP3990889B2 JP 3990889 B2 JP3990889 B2 JP 3990889B2 JP 2001312118 A JP2001312118 A JP 2001312118A JP 2001312118 A JP2001312118 A JP 2001312118A JP 3990889 B2 JP3990889 B2 JP 3990889B2
Authority
JP
Japan
Prior art keywords
ions
ion trap
mass spectrometer
ion
voltage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2001312118A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003123685A (ja
JP2003123685A5 (enExample
Inventor
昭彦 奥村
集 平林
泉 和気
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi High Tech Corp
Original Assignee
Hitachi High Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi High Technologies Corp filed Critical Hitachi High Technologies Corp
Priority to JP2001312118A priority Critical patent/JP3990889B2/ja
Priority to EP02011538A priority patent/EP1302973B1/en
Priority to US10/153,615 priority patent/US6900430B2/en
Publication of JP2003123685A publication Critical patent/JP2003123685A/ja
Publication of JP2003123685A5 publication Critical patent/JP2003123685A5/ja
Application granted granted Critical
Publication of JP3990889B2 publication Critical patent/JP3990889B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/40Time-of-flight spectrometers
    • H01J49/401Time-of-flight spectrometers characterised by orthogonal acceleration, e.g. focusing or selecting the ions, pusher electrode
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205Device types
    • H01J49/424Three-dimensional ion traps, i.e. comprising end-cap and ring electrodes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
JP2001312118A 2001-10-10 2001-10-10 質量分析装置およびこれを用いる計測システム Expired - Fee Related JP3990889B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2001312118A JP3990889B2 (ja) 2001-10-10 2001-10-10 質量分析装置およびこれを用いる計測システム
EP02011538A EP1302973B1 (en) 2001-10-10 2002-05-23 Mass spectrometer and measurement system and method for time-of-flight mass spectrometry
US10/153,615 US6900430B2 (en) 2001-10-10 2002-05-24 Mass spectrometer and measurement system using the mass spectrometer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2001312118A JP3990889B2 (ja) 2001-10-10 2001-10-10 質量分析装置およびこれを用いる計測システム

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2005344873A Division JP4248540B2 (ja) 2005-11-30 2005-11-30 質量分析装置およびこれを用いる計測システム

Publications (3)

Publication Number Publication Date
JP2003123685A JP2003123685A (ja) 2003-04-25
JP2003123685A5 JP2003123685A5 (enExample) 2005-06-16
JP3990889B2 true JP3990889B2 (ja) 2007-10-17

Family

ID=19130829

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001312118A Expired - Fee Related JP3990889B2 (ja) 2001-10-10 2001-10-10 質量分析装置およびこれを用いる計測システム

Country Status (3)

Country Link
US (1) US6900430B2 (enExample)
EP (1) EP1302973B1 (enExample)
JP (1) JP3990889B2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008108739A (ja) * 2007-11-26 2008-05-08 Hitachi High-Technologies Corp 質量分析装置およびこれを用いる計測システム
US10324071B2 (en) 2014-11-17 2019-06-18 Shimadzu Corporation Chromatograph mass spectrometer

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2388955B (en) * 2001-10-22 2004-09-01 * Micromass Limited Mass spectrometer
US7095015B2 (en) 2001-10-22 2006-08-22 Micromass Uk Limited Mass spectrometer
CA2412656C (en) 2001-11-22 2011-04-19 Micromass Limited Mass spectrometer
US6703611B2 (en) * 2002-02-25 2004-03-09 The University Of North Carolina At Chapel Hill Electrospray ionization device
US7102126B2 (en) * 2002-08-08 2006-09-05 Micromass Uk Limited Mass spectrometer
US7049583B2 (en) * 2002-08-08 2006-05-23 Micromass Uk Limited Mass spectrometer
US7087897B2 (en) * 2003-03-11 2006-08-08 Waters Investments Limited Mass spectrometer
JP4284167B2 (ja) 2003-12-24 2009-06-24 株式会社日立ハイテクノロジーズ イオントラップ/飛行時間型質量分析計による精密質量測定方法
GB0404285D0 (en) * 2004-02-26 2004-03-31 Shimadzu Res Lab Europe Ltd A tandem ion-trap time-of flight mass spectrometer
JP4300154B2 (ja) 2004-05-14 2009-07-22 株式会社日立ハイテクノロジーズ イオントラップ/飛行時間質量分析計およびイオンの精密質量測定方法
JP4649234B2 (ja) * 2004-07-07 2011-03-09 日本電子株式会社 垂直加速型飛行時間型質量分析計
US7102129B2 (en) * 2004-09-14 2006-09-05 Thermo Finnigan Llc High-Q pulsed fragmentation in ion traps
GB0427632D0 (en) * 2004-12-17 2005-01-19 Micromass Ltd Mass spectrometer
JP4644506B2 (ja) * 2005-03-28 2011-03-02 株式会社日立ハイテクノロジーズ 質量分析装置
CA2636822C (en) * 2006-01-11 2015-03-03 Mds Inc., Doing Business Through Its Mds Sciex Division Fragmenting ions in mass spectrometry
WO2007095378A2 (en) * 2006-02-15 2007-08-23 University Of Virginia Patent Foundation Mass tagging for quantitative analysis of biomolecules using 13c labeled phenylisocyanate
JP4902230B2 (ja) * 2006-03-09 2012-03-21 株式会社日立ハイテクノロジーズ 質量分析装置
GB0607542D0 (en) * 2006-04-13 2006-05-24 Thermo Finnigan Llc Mass spectrometer
DE112007000931B4 (de) 2006-04-13 2014-05-22 Thermo Fisher Scientific (Bremen) Gmbh Ionenenergiestreuungsreduzierung für ein Massenspektrometer
JP4802032B2 (ja) * 2006-04-14 2011-10-26 日本電子株式会社 タンデム型質量分析装置
JP4802041B2 (ja) * 2006-05-23 2011-10-26 日本電子株式会社 らせん軌道型飛行時間型質量分析計
US7755035B2 (en) 2006-08-30 2010-07-13 Hitachi High-Technologies Corporation Ion trap time-of-flight mass spectrometer
US7633059B2 (en) * 2006-10-13 2009-12-15 Agilent Technologies, Inc. Mass spectrometry system having ion deflector
TWI484529B (zh) * 2006-11-13 2015-05-11 Mks Instr Inc 離子阱質譜儀、利用其得到質譜之方法、離子阱、捕捉離子阱內之離子之方法和設備
GB0624679D0 (en) * 2006-12-11 2007-01-17 Shimadzu Corp A time-of-flight mass spectrometer and a method of analysing ions in a time-of-flight mass spectrometer
GB0624993D0 (en) 2006-12-14 2007-01-24 Micromass Ltd Mass spectrometer
WO2008071993A2 (en) * 2006-12-14 2008-06-19 Micromass Uk Limited Mass spectrometer
GB2445169B (en) 2006-12-29 2012-03-14 Thermo Fisher Scient Bremen Parallel mass analysis
JP5341323B2 (ja) * 2007-07-17 2013-11-13 株式会社日立ハイテクノロジーズ 質量分析装置
JP4966780B2 (ja) * 2007-07-30 2012-07-04 株式会社日立ハイテクノロジーズ 液体クロマトグラフ/質量分析計を用いた分析方法
JP2009068981A (ja) * 2007-09-13 2009-04-02 Hitachi High-Technologies Corp 質量分析システム及び質量分析方法
US8334506B2 (en) 2007-12-10 2012-12-18 1St Detect Corporation End cap voltage control of ion traps
JP5094362B2 (ja) * 2007-12-21 2012-12-12 株式会社日立ハイテクノロジーズ 質量分析装置およびその制御方法
US7709790B2 (en) * 2008-04-01 2010-05-04 Thermo Finnigan Llc Removable ion source that does not require venting of the vacuum chamber
US7973277B2 (en) 2008-05-27 2011-07-05 1St Detect Corporation Driving a mass spectrometer ion trap or mass filter
GB2454962B (en) * 2008-07-25 2009-10-28 Kratos Analytical Ltd Method and apparatus for ion axial spatial distribution focusing
CN102413907B (zh) * 2009-04-13 2015-06-17 萨莫芬尼根有限责任公司 质谱仪中混合的离子布居的获取与分析
JP5314603B2 (ja) * 2010-01-15 2013-10-16 日本電子株式会社 飛行時間型質量分析装置
GB201003566D0 (en) * 2010-03-03 2010-04-21 Ilika Technologies Ltd Mass spectrometry apparatus and methods
CN106055895B (zh) * 2010-09-15 2021-02-19 Dh科技发展私人贸易有限公司 产物离子谱的数据独立获取及参考谱库匹配
JP2012084299A (ja) * 2010-10-08 2012-04-26 Jeol Ltd タンデム型飛行時間型質量分析計
CA2811470C (en) * 2010-11-08 2018-03-20 Dh Technologies Development Pte. Ltd. Systems and methods for rapidly screening samples by mass spectrometry
GB201104220D0 (en) * 2011-03-14 2011-04-27 Micromass Ltd Ion guide with orthogonal sampling
GB201104292D0 (en) 2011-03-15 2011-04-27 Micromass Ltd M/z targets attenuation on time of flight instruments
WO2012132550A1 (ja) 2011-03-25 2012-10-04 株式会社島津製作所 飛行時間型質量分析装置
DE102011100525B4 (de) * 2011-05-05 2015-12-31 Bruker Daltonik Gmbh Betrieb eines Flugzeitmassenspektrometers mit orthogonalem Ionenauspulsen
CN104160473B (zh) * 2012-04-02 2017-03-15 Dh科技发展私人贸易有限公司 使用离子阱跨越质量范围进行连续窗口化获取的系统及方法
EP2850645B1 (en) * 2012-05-18 2018-10-31 DH Technologies Development Pte. Ltd. Systems and methods for using interleaving window widths in tandem mass spectrometry
JP6195528B2 (ja) * 2014-02-19 2017-09-13 東京エレクトロン株式会社 プラズマ処理装置及びその運転方法
GB201409074D0 (en) 2014-05-21 2014-07-02 Thermo Fisher Scient Bremen Ion ejection from a quadrupole ion trap
US9711341B2 (en) * 2014-06-10 2017-07-18 The University Of North Carolina At Chapel Hill Mass spectrometry systems with convective flow of buffer gas for enhanced signals and related methods
US9425033B2 (en) * 2014-06-19 2016-08-23 Bruker Daltonics, Inc. Ion injection device for a time-of-flight mass spectrometer
JP6311791B2 (ja) * 2014-08-08 2018-04-18 株式会社島津製作所 飛行時間型質量分析装置
JP6237907B2 (ja) * 2014-08-19 2017-11-29 株式会社島津製作所 飛行時間型質量分析装置
WO2016042632A1 (ja) * 2014-09-18 2016-03-24 株式会社島津製作所 飛行時間型質量分析装置
EP3404695B1 (en) * 2016-01-12 2019-11-27 Shimadzu Corporation Time-of-flight mass spectrometer
CN113420882B (zh) * 2021-06-17 2023-08-22 南方科技大学 离子阱装置以及离子阱装置的鞍点移动方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5730255A (en) * 1980-07-30 1982-02-18 Toshiba Corp Mass spectrograph
US4650999A (en) * 1984-10-22 1987-03-17 Finnigan Corporation Method of mass analyzing a sample over a wide mass range by use of a quadrupole ion trap
US5479012A (en) * 1992-05-29 1995-12-26 Varian Associates, Inc. Method of space charge control in an ion trap mass spectrometer
US6011259A (en) 1995-08-10 2000-01-04 Analytica Of Branford, Inc. Multipole ion guide ion trap mass spectrometry with MS/MSN analysis
US5689111A (en) * 1995-08-10 1997-11-18 Analytica Of Branford, Inc. Ion storage time-of-flight mass spectrometer
JP2002502085A (ja) * 1998-01-23 2002-01-22 アナリティカ オブ ブランフォード インコーポレーテッド 多極イオンガイドを用いた質量分光測定法
GB9802111D0 (en) * 1998-01-30 1998-04-01 Shimadzu Res Lab Europe Ltd Time-of-flight mass spectrometer
US6483109B1 (en) * 1999-08-26 2002-11-19 University Of New Hampshire Multiple stage mass spectrometer
JP3650551B2 (ja) * 1999-09-14 2005-05-18 株式会社日立製作所 質量分析計
US6570152B1 (en) * 2000-03-03 2003-05-27 Micromass Limited Time of flight mass spectrometer with selectable drift length
US20020119490A1 (en) * 2000-12-26 2002-08-29 Aebersold Ruedi H. Methods for rapid and quantitative proteome analysis
EP1405055A4 (en) * 2001-05-25 2007-05-23 Analytica Of Branford Inc MULTIPLE DETECTTON SYSTEM
CA2412656C (en) * 2001-11-22 2011-04-19 Micromass Limited Mass spectrometer
US6570151B1 (en) * 2002-02-21 2003-05-27 Hitachi Instruments, Inc. Methods and apparatus to control charge neutralization reactions in ion traps

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008108739A (ja) * 2007-11-26 2008-05-08 Hitachi High-Technologies Corp 質量分析装置およびこれを用いる計測システム
US10324071B2 (en) 2014-11-17 2019-06-18 Shimadzu Corporation Chromatograph mass spectrometer

Also Published As

Publication number Publication date
EP1302973B1 (en) 2012-09-12
EP1302973A3 (en) 2006-04-12
US20030066958A1 (en) 2003-04-10
US6900430B2 (en) 2005-05-31
JP2003123685A (ja) 2003-04-25
EP1302973A2 (en) 2003-04-16

Similar Documents

Publication Publication Date Title
JP3990889B2 (ja) 質量分析装置およびこれを用いる計測システム
JP2011119279A (ja) 質量分析装置およびこれを用いる計測システム
US9287101B2 (en) Targeted analysis for tandem mass spectrometry
JP3971958B2 (ja) 質量分析装置
US7999223B2 (en) Multiple ion isolation in multi-reflection systems
CA2441589C (en) Mass spectrometry method and apparatus
US7425699B2 (en) Mass spectrometry method and apparatus
US12394615B2 (en) Apparatus and method for pulsed mode charge detection mass spectrometry
JP2008108739A (ja) 質量分析装置およびこれを用いる計測システム
JP4248540B2 (ja) 質量分析装置およびこれを用いる計測システム
CA2689091C (en) Mass spectrometry method and apparatus
JP2011034981A (ja) 質量分析装置およびこれを用いる計測システム
WO2019211918A1 (ja) 直交加速飛行時間型質量分析装置

Legal Events

Date Code Title Description
A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20040723

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20040723

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20040825

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20040825

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20040825

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20050519

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20050524

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050722

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20051101

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20051130

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20051130

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20060116

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20060210

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20060511

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20060511

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20070723

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20100727

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110727

Year of fee payment: 4

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110727

Year of fee payment: 4

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20120727

Year of fee payment: 5

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20130727

Year of fee payment: 6

LAPS Cancellation because of no payment of annual fees