JP3944080B2 - 液状抗菌組成物 - Google Patents
液状抗菌組成物 Download PDFInfo
- Publication number
- JP3944080B2 JP3944080B2 JP2002555622A JP2002555622A JP3944080B2 JP 3944080 B2 JP3944080 B2 JP 3944080B2 JP 2002555622 A JP2002555622 A JP 2002555622A JP 2002555622 A JP2002555622 A JP 2002555622A JP 3944080 B2 JP3944080 B2 JP 3944080B2
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- anion
- thiocyanate
- iodide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/12—Iodine, e.g. iodophors; Compounds thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/24—Cyanogen or compounds thereof, e.g. hydrogen cyanide, cyanic acid, cyanamide, thiocyanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/18—Iodine; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/40—Peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01007—Peroxidase (1.11.1.7), i.e. horseradish-peroxidase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Description
(1)(I−:SCN−)の質量:質量比が0.1:1〜50:1であり、合計陰イオン質量濃度が少なくとも5mg/kgであるヨウ化物とチオシアン酸塩の陰イオン;
(2)少なくとも質量濃度が0.2g/kgのD−グルコース;
(3)オキシドレダクターゼ酵素のグルコースオキシダーゼおよび、
(4)任意にペルオキシダーゼ、特にラクトペルオキシダーゼ
からなる。
(1) ヨウ化物の陰イオンとチオシアン酸塩の陰イオンとの混合物;
(2) 過ヨウ素酸又はそのアルカリ金属塩;及び
(3) 任意に、ペルオキシダーゼ
を含有する液状抗菌組成物を提供する。
a)防臭剤、例えば、ローション形態の局所投与用のもの、
b)抗細菌皮膚洗浄剤、例えば、ローション形態のもの、
c)抗ニキビ製剤、例えば、ローション又はクリーム形態のもの、
d)運動選手の足部に使用する製剤、例えば、ローション形態のもの、
e)抗ふけ製剤、例えば、シャンプー又はローション形態のもの、
f)歯科用製剤、例えば、一般口内衛生に適したうがい薬、特に、抗プラークの特性を持つもの、及び練り歯磨きやチューインガムおよび薬用ドロップのような歯みがき剤、
g)含浸材料、例えば、傷の包帯、縫合糸、及びデンタルフロス、
h)医薬品、例えば、傷の洗浄、およびやけど治療、下痢止め剤、およびカンジダ症および皮膚糸状菌症のような感染症の治療に適した薬物、
i)眼科製材、例えば、目薬および/又は、コンタクトレンズの消毒、および
j)滅菌剤、例えば、ほ乳用ビン、外科用又は歯科用器具の滅菌用、
等がある。
1.NaSCN 4.2mg
2.KI 7.3mg
3.ラクトペルオキシダーゼ 70 国際単位(internatinal units)
4.過ヨウ素酸 200mg
5.水 100ml まで。
黄色ブドウ球菌 (S.aureus) NCIB 9518
大腸菌 (E.coli) NCIB 8545
カンジダアルビカンス (C.albicans) ATCC 1023
麹菌 (A.niger) ATCC 16404
上記、各有機体すべての殺傷は5分以内に達成された。
Claims (18)
- (1)ヨウ化物の陰イオンとチオシアン酸塩の陰イオンとの混合物;
(2)過ヨウ素酸又はその塩;及び
(3)任意に、ペルオキシダーゼ
を含有する液状抗菌組成物。 - 過ヨウ素酸のアルカリ金属塩を含む請求項1に記載の組成物。
- 過ヨウ素酸又はその塩が、組成物中に組成物の総質量の25〜500ppmの量で含まれている請求項1又は2に記載の組成物。
- 過ヨウ素酸又はその塩が、組成物の総質量の200〜500ppmの量で含まれている請求項3に記載の組成物。
- ヨウ化物の陰イオン:チオシアン酸塩の陰イオンが質量で0.1:1〜50:1の範囲にある請求項1〜4の何れかに記載の組成物。
- ヨウ化物の陰イオン:チオシアン酸塩の陰イオンが質量で0.2:1〜20:1の範囲にある請求項5に記載の組成物。
- ヨウ化物陰イオン及びチオシアン酸塩の陰イオンが合計量で組成物中に組成物の総質量に対して少なくとも5mg/kg含まれている請求項1〜6の何れかに記載の組成物。
- ヨウ化物の陰イオンが組成物中に少なくとも質量濃度で5mg/kg、及びチオシアン酸塩のイオンが質量濃度で少なくとも2mg/kg、組成物の総質量に対して含まれている請求項1〜7の何れかに記載の組成物。
- ペルオキシダーゼを含んでいる請求項1〜8の何れかに記載の組成物。
- ペルオキシダーゼがラクトペルオキシダーゼである請求請9に記載の組成物。
- ペルオキシダーゼが組成物中に少なくとも10酵素単位/kgの量で含まれている請求項9又は10の何れかに記載の組成物。
- 更に、適当な担体が含まれている請求項1〜11の何れかに記載の組成物。
- 担体は水であり、組成物は水性の溶液である請求項12に記載の組成物。
- 担体は更に表面活性剤又は乳化剤を含み、組成物は水中油型乳化剤又は表面活性剤をベースにする溶液である請求項13に記載の組成物。
- 請求項1〜14の何れかに記載の組成物を含む殺菌剤。
- 請求項1〜14の何れかに記載の組成物を含む消毒剤。
- 請求項1〜14の何れかに記載の組成物を含む、ウイルスを抑制し又は死滅させるための薬剤。
- 請求項1〜14の何れかに記載の組成物を含む、胞子を抑制し又は死滅させるための薬剤。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0100643.6A GB0100643D0 (en) | 2001-01-10 | 2001-01-10 | Liquid antimicrobial compositions |
PCT/GB2002/000025 WO2002054872A1 (en) | 2001-01-10 | 2002-01-04 | Liquid antimicrobial compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2004522731A JP2004522731A (ja) | 2004-07-29 |
JP3944080B2 true JP3944080B2 (ja) | 2007-07-11 |
Family
ID=9906582
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2002555622A Expired - Fee Related JP3944080B2 (ja) | 2001-01-10 | 2002-01-04 | 液状抗菌組成物 |
Country Status (16)
Country | Link |
---|---|
US (1) | US6866869B2 (ja) |
EP (1) | EP1349457B1 (ja) |
JP (1) | JP3944080B2 (ja) |
KR (1) | KR100837194B1 (ja) |
CN (1) | CN1258327C (ja) |
AT (1) | ATE333796T1 (ja) |
AU (1) | AU2002217319B2 (ja) |
BR (1) | BR0206262B1 (ja) |
CA (1) | CA2436808C (ja) |
DE (1) | DE60213361T2 (ja) |
DK (1) | DK1349457T3 (ja) |
ES (1) | ES2269689T3 (ja) |
GB (1) | GB0100643D0 (ja) |
MX (1) | MXPA03005740A (ja) |
PT (1) | PT1349457E (ja) |
WO (1) | WO2002054872A1 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MD2069C2 (ro) * | 2001-08-30 | 2003-06-30 | Неогаленафарм, С.Р.Л. | Preparat antiseptic şi procedeu de preparare a lui |
GB0328156D0 (en) * | 2003-12-04 | 2004-01-07 | Basf Ag | Antimicrobial compositions comprising polymeric stabilizers |
GB0413954D0 (en) * | 2004-06-22 | 2004-07-28 | Altunkaya Ali | Compositions for topical treatment |
CA2504014C (en) * | 2005-04-13 | 2013-06-18 | Siamons International Inc. | Non-toxic water soluble inorganic anti-microbial polymer and related methods |
AU2007307921B2 (en) * | 2006-10-10 | 2013-03-28 | Laclede, Inc. | Methods and compositions for the treatment of vaginal diseases employing peroxide-producing enzymes and peroxidases |
EP2987408A1 (en) * | 2014-08-20 | 2016-02-24 | National University of Ireland, Galway | Iodophor composition with improved stability in the presence of organic material |
FR3041269B1 (fr) | 2015-09-17 | 2020-04-17 | Taradon Laboratory | Composition comprenant des ions i2scn- et/ou des ions i(scn)2- |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9002422D0 (en) | 1990-02-03 | 1990-04-04 | Boots Co Plc | Anti-microbial compositions |
DE4301277A1 (de) | 1993-01-11 | 1994-07-14 | Stubinitzky Heinz Guenter | Verfahren zur Sterilisierung von Anlagen für die Milchbehandlung |
GB9406075D0 (en) | 1994-03-26 | 1994-05-18 | Boots Co Plc | Method of killing microorganisms |
US5908614A (en) * | 1995-08-15 | 1999-06-01 | Montgomery; Robert Eric | Peroxidase-activating oral compositions |
US5972355A (en) * | 1997-09-30 | 1999-10-26 | E-L Management Corp. | Stable compositions containing biologically active components |
-
2001
- 2001-01-10 GB GBGB0100643.6A patent/GB0100643D0/en not_active Ceased
-
2002
- 2002-01-04 JP JP2002555622A patent/JP3944080B2/ja not_active Expired - Fee Related
- 2002-01-04 DK DK02729365T patent/DK1349457T3/da active
- 2002-01-04 WO PCT/GB2002/000025 patent/WO2002054872A1/en active IP Right Grant
- 2002-01-04 BR BRPI0206262-3A patent/BR0206262B1/pt not_active IP Right Cessation
- 2002-01-04 KR KR1020037009075A patent/KR100837194B1/ko not_active IP Right Cessation
- 2002-01-04 AU AU2002217319A patent/AU2002217319B2/en not_active Ceased
- 2002-01-04 DE DE60213361T patent/DE60213361T2/de not_active Expired - Lifetime
- 2002-01-04 AT AT02729365T patent/ATE333796T1/de active
- 2002-01-04 CA CA2436808A patent/CA2436808C/en not_active Expired - Fee Related
- 2002-01-04 CN CNB028035690A patent/CN1258327C/zh not_active Expired - Fee Related
- 2002-01-04 PT PT02729365T patent/PT1349457E/pt unknown
- 2002-01-04 EP EP02729365A patent/EP1349457B1/en not_active Expired - Lifetime
- 2002-01-04 MX MXPA03005740A patent/MXPA03005740A/es active IP Right Grant
- 2002-01-04 ES ES02729365T patent/ES2269689T3/es not_active Expired - Lifetime
- 2002-01-04 US US10/250,566 patent/US6866869B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
BR0206262B1 (pt) | 2013-04-24 |
CN1484493A (zh) | 2004-03-24 |
ATE333796T1 (de) | 2006-08-15 |
EP1349457B1 (en) | 2006-07-26 |
WO2002054872A1 (en) | 2002-07-18 |
JP2004522731A (ja) | 2004-07-29 |
CA2436808A1 (en) | 2002-07-18 |
KR20030065591A (ko) | 2003-08-06 |
CN1258327C (zh) | 2006-06-07 |
US20040052778A1 (en) | 2004-03-18 |
ES2269689T3 (es) | 2007-04-01 |
MXPA03005740A (es) | 2003-09-25 |
AU2002217319B2 (en) | 2006-10-05 |
BR0206262A (pt) | 2003-12-23 |
WO2002054872A8 (en) | 2003-10-02 |
DK1349457T3 (da) | 2006-11-27 |
DE60213361T2 (de) | 2007-09-13 |
US6866869B2 (en) | 2005-03-15 |
PT1349457E (pt) | 2006-11-30 |
GB0100643D0 (en) | 2001-02-21 |
EP1349457A1 (en) | 2003-10-08 |
DE60213361D1 (de) | 2006-09-07 |
KR100837194B1 (ko) | 2008-06-13 |
CA2436808C (en) | 2010-08-24 |
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