JP3532192B2 - 毛成長の速度及び特徴の変化 - Google Patents
毛成長の速度及び特徴の変化Info
- Publication number
- JP3532192B2 JP3532192B2 JP50125792A JP50125792A JP3532192B2 JP 3532192 B2 JP3532192 B2 JP 3532192B2 JP 50125792 A JP50125792 A JP 50125792A JP 50125792 A JP50125792 A JP 50125792A JP 3532192 B2 JP3532192 B2 JP 3532192B2
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- hair growth
- composition
- alanosine
- rate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003662 hair growth rate Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 claims abstract description 19
- 239000000203 mixture Substances 0.000 claims abstract description 15
- 230000003779 hair growth Effects 0.000 claims abstract description 14
- 230000000699 topical effect Effects 0.000 claims abstract description 10
- 102000005291 Adenylosuccinate synthase Human genes 0.000 claims abstract description 8
- 108010056443 Adenylosuccinate synthase Proteins 0.000 claims abstract description 8
- 102000030907 Aspartate Carbamoyltransferase Human genes 0.000 claims abstract description 6
- 108091000126 Dihydroorotase Proteins 0.000 claims abstract description 6
- ZZKNRXZVGOYGJT-VKHMYHEASA-N (2s)-2-[(2-phosphonoacetyl)amino]butanedioic acid Chemical compound OC(=O)C[C@@H](C(O)=O)NC(=O)CP(O)(O)=O ZZKNRXZVGOYGJT-VKHMYHEASA-N 0.000 claims description 10
- ZGNLFUXWZJGETL-YUSKDDKASA-N (Z)-[(2S)-2-amino-2-carboxyethyl]-hydroxyimino-oxidoazanium Chemical compound N[C@@H](C\[N+]([O-])=N\O)C(O)=O ZGNLFUXWZJGETL-YUSKDDKASA-N 0.000 claims description 9
- MLFKVJCWGUZWNV-UHFFFAOYSA-N L-alanosine Natural products OC(=O)C(N)CN(O)N=O MLFKVJCWGUZWNV-UHFFFAOYSA-N 0.000 claims description 9
- 239000003098 androgen Substances 0.000 claims description 4
- 231100000252 nontoxic Toxicity 0.000 claims description 4
- 230000003000 nontoxic effect Effects 0.000 claims description 4
- QQWGVQWAEANRTK-UHFFFAOYSA-N bromosuccinic acid Chemical compound OC(=O)CC(Br)C(O)=O QQWGVQWAEANRTK-UHFFFAOYSA-N 0.000 claims description 3
- 229940125532 enzyme inhibitor Drugs 0.000 claims 2
- 239000002532 enzyme inhibitor Substances 0.000 claims 2
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 1
- 229960005261 aspartic acid Drugs 0.000 claims 1
- 235000003704 aspartic acid Nutrition 0.000 claims 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 210000000056 organ Anatomy 0.000 description 13
- 241000699800 Cricetinae Species 0.000 description 6
- 241001465754 Metazoa Species 0.000 description 6
- 210000004209 hair Anatomy 0.000 description 6
- 210000003780 hair follicle Anatomy 0.000 description 6
- 210000003491 skin Anatomy 0.000 description 6
- 238000011282 treatment Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- -1 7-deaza-8-azaguanosine monophosphate Chemical class 0.000 description 4
- 102000004190 Enzymes Human genes 0.000 description 4
- 108090000790 Enzymes Proteins 0.000 description 4
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 239000002773 nucleotide Substances 0.000 description 2
- 125000003729 nucleotide group Chemical group 0.000 description 2
- CWERGRDVMFNCDR-UHFFFAOYSA-N thioglycolic acid Chemical compound OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 description 2
- ZCARDBJHSMTFCZ-UHFFFAOYSA-N 2-(phosphonomethylsulfanylmethyl)butanedioic acid Chemical compound OC(=O)CC(C(O)=O)CSCP(O)(O)=O ZCARDBJHSMTFCZ-UHFFFAOYSA-N 0.000 description 1
- NOIIUHRQUVNIDD-UHFFFAOYSA-N 3-[[oxo(pyridin-4-yl)methyl]hydrazo]-N-(phenylmethyl)propanamide Chemical compound C=1C=CC=CC=1CNC(=O)CCNNC(=O)C1=CC=NC=C1 NOIIUHRQUVNIDD-UHFFFAOYSA-N 0.000 description 1
- NKGPJODWTZCHGF-UHFFFAOYSA-N 9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purine-6-thione Chemical compound OC1C(O)C(CO)OC1N1C(NC=NC2=S)=C2N=C1 NKGPJODWTZCHGF-UHFFFAOYSA-N 0.000 description 1
- 101710107035 Gamma-glutamyltranspeptidase Proteins 0.000 description 1
- 101710173228 Glutathione hydrolase proenzyme Proteins 0.000 description 1
- 241000699673 Mesocricetus auratus Species 0.000 description 1
- CCIAZJGNPJDRLB-BXRBKJIMSA-N OC(=O)[C@@H](N)CN(O)N=O.OC(=O)[C@@H](N)CN(O)N=O Chemical compound OC(=O)[C@@H](N)CN(O)N=O.OC(=O)[C@@H](N)CN(O)N=O CCIAZJGNPJDRLB-BXRBKJIMSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 108091028664 Ribonucleotide Proteins 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 1
- GTARKUZCYSDIEH-UMMCILCDSA-N [(2R,3S,4R,5R)-5-(5-amino-7-oxo-6H-triazolo[4,5-d]pyrimidin-3-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate Chemical compound N1=NC=2C(=O)NC(N)=NC=2N1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O GTARKUZCYSDIEH-UMMCILCDSA-N 0.000 description 1
- 150000003838 adenosines Chemical class 0.000 description 1
- MLFKVJCWGUZWNV-REOHCLBHSA-N alanosine Chemical compound OC(=O)[C@@H](N)CN(O)N=O MLFKVJCWGUZWNV-REOHCLBHSA-N 0.000 description 1
- 229940030486 androgens Drugs 0.000 description 1
- 235000019445 benzyl alcohol Nutrition 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000002951 depilatory effect Effects 0.000 description 1
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 1
- 102000006640 gamma-Glutamyltransferase Human genes 0.000 description 1
- RQFCJASXJCIDSX-UUOKFMHZSA-N guanosine 5'-monophosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O RQFCJASXJCIDSX-UUOKFMHZSA-N 0.000 description 1
- 235000013928 guanylic acid Nutrition 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 229940116298 l- malic acid Drugs 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- RUOJZAUFBMNUDX-UHFFFAOYSA-N propylene carbonate Chemical compound CC1COC(=O)O1 RUOJZAUFBMNUDX-UHFFFAOYSA-N 0.000 description 1
- 239000002719 pyrimidine nucleotide Substances 0.000 description 1
- 150000003230 pyrimidines Chemical class 0.000 description 1
- 239000002336 ribonucleotide Substances 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
- A61Q7/02—Preparations for inhibiting or slowing hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US603,999 | 1990-10-24 | ||
| US07/603,999 US5095007A (en) | 1990-10-24 | 1990-10-24 | Alteration of rate and character of hair growth |
| PCT/US1991/007839 WO1992007569A1 (fr) | 1990-10-24 | 1991-10-22 | Modification de la vitesse de repousse et des caracteristiques des poils |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH06502648A JPH06502648A (ja) | 1994-03-24 |
| JP3532192B2 true JP3532192B2 (ja) | 2004-05-31 |
Family
ID=24417775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50125792A Expired - Lifetime JP3532192B2 (ja) | 1990-10-24 | 1991-10-22 | 毛成長の速度及び特徴の変化 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5095007A (fr) |
| EP (1) | EP0554363B1 (fr) |
| JP (1) | JP3532192B2 (fr) |
| AT (1) | ATE167625T1 (fr) |
| AU (1) | AU662112B2 (fr) |
| CA (1) | CA2094491C (fr) |
| DE (1) | DE69129663T2 (fr) |
| ES (1) | ES2117646T3 (fr) |
| WO (1) | WO1992007569A1 (fr) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9118866D0 (en) * | 1991-09-04 | 1991-10-23 | Unilever Plc | Cosmetic composition |
| ATE218273T1 (de) * | 1991-11-05 | 2002-06-15 | Gillette Co | Veränderung der geschindigkeit und der art des haarwuchses |
| US5364885A (en) * | 1992-11-13 | 1994-11-15 | Ahluwalia Gurpreet S | Reduction of hair growth |
| US6743419B1 (en) | 1992-12-22 | 2004-06-01 | The Gillette Company | Method of reducing hair growth employing sulfhydryl active compounds |
| US5411991A (en) * | 1992-12-22 | 1995-05-02 | Shander; Douglas | Method of reducing hair growth employing sulfhydryl active compounds |
| US5648394A (en) * | 1993-05-27 | 1997-07-15 | Boxall; Brian Alfred | Topical composition for inhibiting hair growth |
| US6414017B2 (en) | 1993-05-28 | 2002-07-02 | The Gillette Company | Inhibition of hair growth |
| US6239170B1 (en) | 1993-05-28 | 2001-05-29 | Gurpreet S. Ahluwalia | Inhibition of hair growth |
| US5474763A (en) * | 1994-03-11 | 1995-12-12 | Shander; Douglas | Reduction of hair growth |
| US5468476A (en) * | 1994-03-16 | 1995-11-21 | Ahluwalia; Gurpreet S. | Reduction of hair growth |
| US5455234A (en) * | 1994-03-16 | 1995-10-03 | Ahluwalia; Gurpreet S. | Inhibition of hair growth |
| US5554608A (en) * | 1994-09-28 | 1996-09-10 | Ahluwalia; Gurpreet S. | Inhibition of hair growth |
| EP0812185B1 (fr) * | 1995-02-28 | 2002-07-03 | The Gillette Company | Emploi de suppresseurs d'angiogenese pour inhiber la pousse des poils |
| US5674477A (en) * | 1995-02-28 | 1997-10-07 | Ahluwalia; Gurpreet S. | Reduction of hair growth |
| US5645825A (en) * | 1995-06-07 | 1997-07-08 | The Procter & Gamble Company | Depilatory compositions comprising sulfhydryl compounds |
| US5728736A (en) * | 1995-11-29 | 1998-03-17 | Shander; Douglas | Reduction of hair growth |
| US5652273A (en) * | 1995-11-30 | 1997-07-29 | Henry; James | Reduction of hair growth |
| US6407056B1 (en) | 1996-07-12 | 2002-06-18 | Johnson & Johnson Consumer Companies, Inc. | Methods for altering hair growth and hair pigmentation by apoptosis in the follicular papillae and compositions therefor |
| US5908867A (en) * | 1996-07-18 | 1999-06-01 | Henry; James P. | Reduction of hair growth |
| US5840752A (en) * | 1996-11-21 | 1998-11-24 | Henry; James P. | Reduction of hair growth |
| ZA9711121B (en) * | 1996-12-13 | 1998-06-23 | Handelman Joseph H | Reduction of hair growth. |
| US6037326A (en) * | 1996-12-31 | 2000-03-14 | Styczynski; Peter | Reduction of hair growth |
| AUPO690297A0 (en) | 1997-05-20 | 1997-06-12 | Kahale, Laura | Prevention/retardation of hair growth |
| US5939458A (en) * | 1997-09-22 | 1999-08-17 | Henry; James P. | Reduction of hair growth |
| US6146620A (en) * | 1997-12-09 | 2000-11-14 | Janowski; Leonard J. | Shaving compositions useful in altering the growth of male beard hair |
| JP3973748B2 (ja) * | 1998-01-14 | 2007-09-12 | 花王株式会社 | 発毛抑制剤 |
| US5958946A (en) * | 1998-01-20 | 1999-09-28 | Styczynski; Peter | Modulation of hair growth |
| US6060471A (en) * | 1998-01-21 | 2000-05-09 | Styczynski; Peter | Reduction of hair growth |
| US6020006A (en) * | 1998-10-27 | 2000-02-01 | The Gillette Company | Reduction of hair growth |
| US6121269A (en) * | 1999-02-22 | 2000-09-19 | Henry; James P. | Reduction of hair growth |
| US6235737B1 (en) | 2000-01-25 | 2001-05-22 | Peter Styczynski | Reduction of hair growth |
| US6299865B1 (en) | 2000-05-02 | 2001-10-09 | Peter Styczynski | Reduction of hair growth |
| US7439271B2 (en) | 2001-06-27 | 2008-10-21 | The Gillette Company | Reduction of hair growth |
| JP4759182B2 (ja) * | 2001-08-03 | 2011-08-31 | 花王株式会社 | 水溶性ショウキョウエキス |
| US6743822B2 (en) | 2001-08-10 | 2004-06-01 | The Gillette Company | Reduction of hair growth |
| US7261878B2 (en) * | 2001-08-10 | 2007-08-28 | The Gillette Company | Reduction of hair growth |
| US20030036561A1 (en) * | 2001-08-10 | 2003-02-20 | Peter Styczynski | Reduction of hair growth |
| NZ531006A (en) * | 2001-08-15 | 2005-01-28 | Women First Healthcare Inc | Topical composition for follicular delivery of an ornithine decarboxylase inhibitor |
| US6730809B2 (en) | 2001-08-29 | 2004-05-04 | Women First Healthcare, Inc. | Processes for the production of α-difluoromethyl ornithine (DFMO) |
| US7160921B2 (en) * | 2002-01-29 | 2007-01-09 | The Gillette Company | Reduction of hair growth |
| US20040198821A1 (en) * | 2002-01-29 | 2004-10-07 | Hwang Cheng Shine | Reduction of hair growth |
| US20030199584A1 (en) * | 2002-04-11 | 2003-10-23 | Ahluwalia Gurpreet S. | Reduction of hair growth |
| US20040141935A1 (en) * | 2003-01-21 | 2004-07-22 | Peter Styczynski | Reduction of hair growth |
| US7015349B2 (en) * | 2003-03-26 | 2006-03-21 | The Gillette Company | Reduction of hair growth |
| US20050031699A1 (en) * | 2003-06-26 | 2005-02-10 | L'oreal | Porous particles loaded with cosmetically or pharmaceutically active compounds |
| US20050038473A1 (en) * | 2003-07-14 | 2005-02-17 | Dov Tamarkin | Device and method for the treatment of pilosebaceous disorders |
| US20050249685A1 (en) * | 2004-04-27 | 2005-11-10 | Natalia Botchkareva | Reduction of hair growth |
| WO2006023010A1 (fr) * | 2004-08-18 | 2006-03-02 | Salmedix, Inc. | Formulations d'alanosine et procedes d'utilisation |
| KR20070086176A (ko) * | 2004-12-22 | 2007-08-27 | 더 지렛트 캄파니 | 모발 성장 감소 |
| CA2589762A1 (fr) * | 2004-12-22 | 2006-06-29 | The Gillette Company | Diminution de la pousse des poils due aux inhibiteurs de la survivine |
| US20060263438A1 (en) * | 2005-05-17 | 2006-11-23 | L'oreal | Gelled oil particles for targeting sebaceous glands and/or hair follicles |
| US7618956B2 (en) * | 2005-05-31 | 2009-11-17 | The Gillette Company | Reduction of hair growth |
| US20070059264A1 (en) * | 2005-09-13 | 2007-03-15 | Ahluwalia Gurpreet S | Reduction of hair growth |
| US7727516B2 (en) * | 2006-02-28 | 2010-06-01 | The Procter & Gamble Company | Reduction of hair growth |
| FR2944443B1 (fr) | 2009-04-21 | 2012-11-09 | Arkema France | Procede de fabrication de particules de poudre libre a base de polyamide impregnee, et particules de poudre libre a base de polyamide ayant une teneur d'au moins 25% en poids d'au moins un agent cosmetique ou pharmaceutique |
| FR2953716B1 (fr) | 2009-12-16 | 2015-03-27 | Oreal | Kit de formulation d'un produit cosmetique |
| WO2018118808A1 (fr) | 2016-12-19 | 2018-06-28 | The Broad Institute, Inc. | Méthodes de traitement des troubles du spectre autistique |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4720480A (en) * | 1985-02-28 | 1988-01-19 | Dai Nippon Insatsu Kabushiki Kaisha | Sheet for heat transference |
| FR1505475A (fr) * | 1966-10-25 | 1967-12-15 | Docteur Jacques Auclair Lab Du | Composition cosmétique |
| BE793306A (fr) * | 1971-12-23 | 1973-04-16 | Waldhof Aschaffenburg Papier | Produit cosmetique |
| US4885289A (en) * | 1983-12-12 | 1989-12-05 | Breuer Miklos M | Alteration of character of male beard growth |
| US4720489A (en) * | 1984-10-15 | 1988-01-19 | Douglas Shander | Hair growth modification with ornithine decarboxylase inhibitors |
| EP0328834A1 (fr) * | 1988-02-16 | 1989-08-23 | Merrell Dow Pharmaceuticals Inc. | Inhibiteurs d'aspartate transcarbamylase |
| SE466826B (sv) * | 1990-06-28 | 1992-04-06 | Asea Brown Boveri | Saett att framstaella en metalloxidvaristor med foerbaettrad energihaallfasthet |
-
1990
- 1990-10-24 US US07/603,999 patent/US5095007A/en not_active Expired - Lifetime
-
1991
- 1991-10-22 CA CA002094491A patent/CA2094491C/fr not_active Expired - Lifetime
- 1991-10-22 DE DE69129663T patent/DE69129663T2/de not_active Expired - Lifetime
- 1991-10-22 EP EP91920173A patent/EP0554363B1/fr not_active Expired - Lifetime
- 1991-10-22 AT AT91920173T patent/ATE167625T1/de not_active IP Right Cessation
- 1991-10-22 ES ES91920173T patent/ES2117646T3/es not_active Expired - Lifetime
- 1991-10-22 WO PCT/US1991/007839 patent/WO1992007569A1/fr active IP Right Grant
- 1991-10-22 JP JP50125792A patent/JP3532192B2/ja not_active Expired - Lifetime
- 1991-10-22 AU AU89289/91A patent/AU662112B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| WO1992007569A1 (fr) | 1992-05-14 |
| ATE167625T1 (de) | 1998-07-15 |
| DE69129663D1 (de) | 1998-07-30 |
| CA2094491A1 (fr) | 1992-04-25 |
| JPH06502648A (ja) | 1994-03-24 |
| EP0554363A4 (en) | 1993-09-15 |
| US5095007A (en) | 1992-03-10 |
| ES2117646T3 (es) | 1998-08-16 |
| AU662112B2 (en) | 1995-08-24 |
| CA2094491C (fr) | 2003-01-28 |
| EP0554363A1 (fr) | 1993-08-11 |
| AU8928991A (en) | 1992-05-26 |
| EP0554363B1 (fr) | 1998-06-24 |
| DE69129663T2 (de) | 1999-01-21 |
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| JP3532192B2 (ja) | 毛成長の速度及び特徴の変化 | |
| EP0750489B1 (fr) | Inhibition de la pousse des poils | |
| CA2163534C (fr) | Inhibition de la croissance capillaire | |
| AU681776B2 (en) | Inhibition of hair growth | |
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