JP3032576B2 - ヌクレオシドの新規なリン脂質誘導体、それらの製造法、並びに抗ウイルス性医薬としてのそれらの使用 - Google Patents
ヌクレオシドの新規なリン脂質誘導体、それらの製造法、並びに抗ウイルス性医薬としてのそれらの使用Info
- Publication number
- JP3032576B2 JP3032576B2 JP3513882A JP51388291A JP3032576B2 JP 3032576 B2 JP3032576 B2 JP 3032576B2 JP 3513882 A JP3513882 A JP 3513882A JP 51388291 A JP51388291 A JP 51388291A JP 3032576 B2 JP3032576 B2 JP 3032576B2
- Authority
- JP
- Japan
- Prior art keywords
- dideoxy
- propyl ester
- decyloxy
- dodecylmercapto
- phosphate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4026265,0 | 1990-08-20 | ||
DE4026265A DE4026265A1 (de) | 1990-08-20 | 1990-08-20 | Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel |
PCT/EP1991/001541 WO1992003462A1 (de) | 1990-08-20 | 1991-08-14 | Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH06500543A JPH06500543A (ja) | 1994-01-20 |
JP3032576B2 true JP3032576B2 (ja) | 2000-04-17 |
Family
ID=6412536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3513882A Expired - Fee Related JP3032576B2 (ja) | 1990-08-20 | 1991-08-14 | ヌクレオシドの新規なリン脂質誘導体、それらの製造法、並びに抗ウイルス性医薬としてのそれらの使用 |
Country Status (10)
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7026469B2 (en) * | 2000-10-19 | 2006-04-11 | Wake Forest University School Of Medicine | Compositions and methods of double-targeting virus infections and cancer cells |
RU2293739C2 (ru) * | 2002-07-26 | 2007-02-20 | Закрытое акционерное общество "Производственно-коммерческая Ассоциация АЗТ" | 5`-холинфосфат 3`-азидо-3`-дезокситимидина как антивирусный агент |
-
1991
- 1991-08-12 TW TW080106360A patent/TW207544B/zh active
- 1991-08-14 RO RO93-00149A patent/RO115163B1/ro unknown
- 1991-08-14 KR KR1019930700473A patent/KR970011307B1/ko not_active IP Right Cessation
- 1991-08-14 JP JP3513882A patent/JP3032576B2/ja not_active Expired - Fee Related
- 1991-08-14 RU RU93005146A patent/RU2104282C1/ru not_active IP Right Cessation
- 1991-08-14 HU HU9300468A patent/HU220611B1/hu unknown
- 1991-08-15 MX MX9100676A patent/MX9100676A/es unknown
- 1991-08-16 NZ NZ239422A patent/NZ239422A/xx not_active IP Right Cessation
- 1991-08-19 ZA ZA916542A patent/ZA916542B/xx unknown
-
1993
- 1993-02-11 CZ CZ1993180A patent/CZ287942B6/cs not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH06500543A (ja) | 1994-01-20 |
KR930701470A (ko) | 1993-06-11 |
HU9300468D0 (en) | 1993-05-28 |
CZ287942B6 (cs) | 2001-03-14 |
NZ239422A (en) | 1993-09-27 |
HUT62910A (en) | 1993-06-28 |
RO115163B1 (ro) | 1999-11-30 |
CZ18093A3 (en) | 1993-06-16 |
RU2104282C1 (ru) | 1998-02-10 |
ZA916542B (en) | 1992-05-27 |
HU220611B1 (hu) | 2002-03-28 |
TW207544B (US07026469-20060411-C00007.png) | 1993-06-11 |
MX9100676A (es) | 1992-04-01 |
KR970011307B1 (ko) | 1997-07-09 |
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