JP3022914B2 - Fast dissolving fumaric acid preparation - Google Patents
Fast dissolving fumaric acid preparationInfo
- Publication number
- JP3022914B2 JP3022914B2 JP2170450A JP17045090A JP3022914B2 JP 3022914 B2 JP3022914 B2 JP 3022914B2 JP 2170450 A JP2170450 A JP 2170450A JP 17045090 A JP17045090 A JP 17045090A JP 3022914 B2 JP3022914 B2 JP 3022914B2
- Authority
- JP
- Japan
- Prior art keywords
- fumaric acid
- coating
- water
- acid preparation
- coating agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Seasonings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
【発明の詳細な説明】 〔産業上の利用分野〕 本発明は、食品に添加することにより、食品の風味改
良に効果を奏する即溶解性フマール酸製剤に関するもの
である。Description: TECHNICAL FIELD The present invention relates to a fast-dissolving fumaric acid preparation which is effective when added to food to improve the flavor of the food.
一般に、フマール酸は、食品に対する酸味料やpH調整
剤として広く用いられている。しかしながら、フマール
酸は、疎水性であるため水に対する溶解度が低く利用し
にくいので、従来からその溶解性を向上させるための研
究が続けられてきた。In general, fumaric acid is widely used as an acidulant and a pH adjuster for foods. However, fumaric acid has low solubility in water due to its hydrophobicity and is difficult to use. Therefore, studies for improving the solubility have been continued.
その既往の技術としては、大量の溶媒にフマール酸お
よび被覆剤を溶解し、ついで溶媒を蒸発させたのち粉砕
するという方法があるが、この方法は、工程が複雑であ
る上、大量の溶媒を取り扱うのでどうしてもコストの上
昇がさけられなかつた。As a conventional technique, there is a method of dissolving fumaric acid and a coating agent in a large amount of a solvent, then evaporating the solvent, and then pulverizing the solution.This method is complicated and requires a large amount of the solvent. The cost was inevitably raised because of handling.
これを解決するものとして、たとえば水溶性ポリマー
などを被覆剤として用い、フマール酸を被覆することに
よつてフマール酸の水に対する溶解性を向上させる方法
（特開昭60−38453号公報、特開昭60−196436号公報）
などが提案された。In order to solve this, for example, a method of improving the solubility of fumaric acid in water by coating with fumaric acid using a water-soluble polymer or the like as a coating agent (JP-A-60-38453, JP-A-60-38453, No. 60-196436)
And so on.
また、一方、粉末状のフマール酸を芯物質として、そ
れを被覆剤で被覆し、フマール酸の水溶性を高める研究
がかなり古くから行なわれており、おおよそ二通りの方
法が一般的になつている。その一つは、溶解した被覆剤
に芯物質を懸濁させたのち、スプレーまたは回転デイス
クを用いて噴霧し、冷却固化せしめることにより被覆物
を得るもの（たとえば、特公昭50−13192号「養魚用生
餌飼料組成物」、特開昭58−205461号「養魚用飼料」
等）である。On the other hand, studies have been conducted for a long time to improve the water solubility of fumaric acid by coating powdery fumaric acid as a core substance and coating it with a coating agent for a long time, and roughly two methods are generally used. I have. One is to obtain a coating by suspending a core substance in a dissolved coating agent, spraying it with a spray or a rotating disk, and solidifying it by cooling (for example, Japanese Patent Publication No. 50-13192, "Fish Farming"). Feed composition for live feed '', JP-A-58-205461 `` Feed for fish farming ''
Etc.).
また、他の方法としては、流動層法と呼ばれる方法が
あり、芯物質を下部からの風力で浮遊させておき、その
上部または側面から溶解した被覆剤を噴霧して被覆を行
なうか、またはこれに類似した流動層を使用する方法
（たとえば、特開昭50−52221号「ビタミン粒子材料を
被覆する方法」等）がある。As another method, there is a method called a fluidized bed method, in which a core substance is suspended by wind force from below and coating is performed by spraying a dissolved coating agent from above or on the side, or (For example, Japanese Patent Application Laid-Open No. 50-52221, "Method for Coating Vitamin Particle Material").
このように、フマール酸の水に対する溶解性を改善す
る目的で種々の検討がなされてきたが、いまだに満足で
きるものはなく、フマール酸を水に溶解するためにはど
うしても手間と時間とが必要であつた。As described above, various studies have been made with the aim of improving the solubility of fumaric acid in water, but none of them have been satisfactory yet, and it takes time and effort to dissolve fumaric acid in water. Atsuta.
本発明者らは、これら従来のフマール酸製剤の持つ欠
点を解消するため鋭意研究を重ねた結果、芯物質の粉末
状のフマール酸を被覆するための被覆剤として、融点40
℃以上の水溶性の界面活性剤を粉粒体として用い、しか
もそれを芯物質のフマール酸に接触、衝突させてフマー
ル酸を被覆することにより、フマール酸の水溶性を極度
に高め得ることを知り、本発明を完成するに至つた。The present inventors have conducted intensive studies to solve the disadvantages of these conventional fumaric acid preparations, and as a result, as a coating material for coating the core substance powdery fumaric acid, a melting point of 40%.
The use of a water-soluble surfactant at a temperature of at least ℃ as a granular material, and contacting and colliding with the fumaric acid of the core substance to coat the fumaric acid, it is possible to extremely increase the water solubility of fumaric acid. As a result, the present invention was completed.
そして、本発明の目的は、容易かつ安価に製造するこ
とができ、冷水に対しても即溶解性を有するフマール酸
を提供することにある。An object of the present invention is to provide fumaric acid that can be easily and inexpensively manufactured and has immediate solubility in cold water.
本発明に用いるフマール酸は、通常の製造法によつて
得られる粒度200メツシユ以下のものである。また、前
記既往の技術により被覆剤を被覆したフマール酸を原料
として用いることにより、溶解性をさらに高めることが
できる。The fumaric acid used in the present invention has a particle size of 200 mesh or less obtained by a usual production method. Further, by using fumaric acid coated with a coating agent by the above-mentioned conventional technique as a raw material, the solubility can be further enhanced.
本発明に用いる界面活性剤としては、ポリグリセリン
脂肪酸エステル、シヨ糖脂肪酸エステル、サポニンなど
の中から水溶性で融点が40℃以上のものを粉粒体として
単独で、または適宜組み合わせて使用することができ
る。特に三菱化成食品株式会社製のシヨ糖脂肪酸エステ
ルＦ−1570,P−1670などが適している。As the surfactant used in the present invention, a polyglycerol fatty acid ester, a sucrose fatty acid ester, a saponin, or the like, which is water-soluble and has a melting point of 40 ° C. or more, used alone or in an appropriate combination as powders Can be. Particularly suitable are sucrose fatty acid esters F-1570 and P-1670 manufactured by Mitsubishi Kasei Foods Corporation.
本発明のフマール酸製剤を製造するには、芯物質であ
る粉末状のフマール酸と被覆剤である融点40℃以上の水
溶性の界面活性剤の粉粒体とを互いに接触、衝突させて
フマール酸を被覆すればよく、その装置としては、ボー
ルミル、電気乳鉢、高能率粉体混合装置、高速気流の対
流により粉体を接触させる装置等を使用することができ
る。この際、あまり過激な条件で作用させると、芯物質
であるフマール酸の微粉砕が起こる危険があるため、で
きるだけ温和な条件で行なうことが望ましい。また、こ
れらの装置により作用させるのに先駆けて、芯物質と被
覆剤とを予備混合しておくと、被覆効率をさらに高める
ことができる。To produce the fumaric acid preparation of the present invention, powdery fumaric acid as a core substance and powdery particles of a water-soluble surfactant having a melting point of 40 ° C. or more as a coating material are brought into contact with each other and collided with each other to form fumaric acid. An acid may be coated, and examples of the device include a ball mill, an electric mortar, a high-efficiency powder mixing device, and a device for bringing powder into contact by convection of high-speed airflow. At this time, if it is used under extremely extreme conditions, there is a risk that fine particles of fumaric acid, which is the core substance, may occur. If the core substance and the coating agent are preliminarily mixed before being operated by these devices, the coating efficiency can be further increased.
なおこの場合、芯物質と被覆剤との混合比としては、
重量比で芯物質１に対して被覆剤（0.1〜50）の範囲で
用いることが可能であるが、芯物質と被覆剤との粒径比
との関係でこの範囲内で適宜選定することが必要であ
る。粒径比が大きい場合には混合比を大きくすることが
できるが、粒径比が小さい場合には混合比を４以下にす
ることが望ましい。混合比は、単に小さくすれば被覆効
率が高められるわけでなく、むしろ大きい方が性能がよ
い場合もある。また、同じ混合比でも、被覆剤を数回に
分けて被覆せしめることにより、被覆効率をさらに高め
ることができる。In this case, as a mixing ratio of the core material and the coating agent,
Although it is possible to use the core material 1 in a weight ratio within the range of the coating agent (0.1 to 50) with respect to the core material 1, it can be appropriately selected within this range in relation to the particle size ratio of the core material and the coating agent. is necessary. When the particle size ratio is large, the mixing ratio can be increased. However, when the particle size ratio is small, the mixing ratio is desirably 4 or less. Simply decreasing the mixing ratio does not necessarily increase the coating efficiency, but rather increasing the mixing ratio may provide better performance. Even with the same mixing ratio, the coating efficiency can be further increased by coating the coating agent several times.
本発明の即溶解性フマール酸製剤は、これまでに開発
されている製剤に比べて被覆効率を高めることができ、
結果的にフマール酸の水に対する溶解度を飛躍的に高め
ることが可能となつた。しかも、被覆効率がよいので被
覆剤の使用量を節約でき、また芯物質であるフマール酸
と被覆剤である融点40℃以上の水溶性の界面活性剤とを
互いに接触、衝突させて被覆する方法を用いるため、製
造コストが従来の製造方法に比べて安価である。The rapidly dissolving fumaric acid preparation of the present invention can increase the coating efficiency as compared with the preparations developed so far,
As a result, it became possible to dramatically increase the solubility of fumaric acid in water. Moreover, since the coating efficiency is high, the amount of the coating agent used can be saved, and a method in which fumaric acid as the core substance and a water-soluble surfactant having a melting point of 40 ° C. or more as the coating agent are brought into contact with and collided with each other. Is used, the manufacturing cost is lower than that of the conventional manufacturing method.
以下、実施例、比較例および試験例により本発明をさ
らに詳しく説明する。Hereinafter, the present invention will be described in more detail with reference to Examples, Comparative Examples, and Test Examples.
実施例１ フマール酸（日本油脂株式会社製品）350gとシヨ糖脂
肪酸エステルＰ−1670（三菱化成食品株式会社製品）5g
とを奈良ハイブリタイゼーシヨンシステム（株式会社奈
良機械製作所製）にかけ、20分間処理し本発明のフマー
ル酸製剤を得た。Example 1 350 g of fumaric acid (product of NOF Corporation) and 5 g of sucrose sugar fatty acid ester P-1670 (product of Mitsubishi Kasei Food Co., Ltd.)
Was subjected to a Nara Hybridization System (manufactured by Nara Machinery Co., Ltd.) and treated for 20 minutes to obtain a fumaric acid preparation of the present invention.
実施例２ フマール酸（日本油脂株式会社製品）をジエツト粉砕
機（日本ニユーマチツク株式会社製）により粉砕したも
の100gをシヨ糖脂肪酸エステルＰ−1670（三菱化成食品
株式会社製品）5gと混合し、ヘンシエルミキサーにか
け、15分間処理し本発明のフマール酸製剤を得た。Example 2 100 g of fumaric acid (a product of Nippon Oil & Fats Co., Ltd.) pulverized by a jet pulverizer (manufactured by Nippon New Mac Co., Ltd.) was mixed with 5 g of sucrose fatty acid ester P-1670 (a product of Mitsubishi Kasei Food Co., Ltd.) The mixture was placed in a shell mixer and treated for 15 minutes to obtain a fumaric acid preparation of the present invention.
実施例３ フマール酸（日本油脂株式会社製品）100gとキラヤサ
ポニン粉末（丸善化成株式会社製品）0.5gとをメカノミ
ル（岡田精機株式会社製）に入れ、５分間処理し本発明
のフマール酸製剤を得た。Example 3 100 g of fumaric acid (product of Nippon Yushi Co., Ltd.) and 0.5 g of Kirayasaponin powder (product of Maruzen Kasei Co., Ltd.) were placed in a mechanomill (manufactured by Okada Seiki Co., Ltd.) and treated for 5 minutes to give a fumaric acid preparation of the present invention Obtained.
比較例１ 未処理のフマール酸（日本油脂株式会社製品）そのも
のを比較品とした。Comparative Example 1 Untreated fumaric acid (product of NOF Corporation) itself was used as a comparative product.
比較例２ 一般市販のフマール酸製剤そのものを比較品とした。Comparative Example 2 A commercially available fumaric acid preparation itself was used as a comparative product.
試験例１ 実施例１〜３、比較例1,2で得られた本発明のフマー
ル酸製剤および比較品を、20℃の水の中に濃度0.5％と
なるように投入し、マグネチツクスターラー（約500rp
m）で撹拌し、完全に溶解するまでの時間を測定した。
結果は表１に示した。Test Example 1 The fumaric acid preparation and the comparative product of the present invention obtained in Examples 1 to 3 and Comparative Examples 1 and 2 were put into water at 20 ° C. so as to have a concentration of 0.5%, and a magnetic stirrer ( About 500rp
m) and the time to complete dissolution was measured.
The results are shown in Table 1.
試験例２ 試験例１において、試料を投入する水の温度を40℃と
し、その濃度を1.0％とする以外は、試験例１に準じて
行ない、試料が完全に溶解するまでの時間を測定した。
結果は表２に示した。 Test Example 2 In Test Example 1, the time until the sample was completely dissolved was measured in the same manner as in Test Example 1, except that the temperature of the water into which the sample was charged was 40 ° C. and the concentration was 1.0%. .
The results are shown in Table 2.
以上の表１、表２の結果から明らかなように、本発明
の即溶解性フマール酸製剤は、比較品に比べて水に対す
る溶解性が優れていることが分かる。 As is clear from the above results of Tables 1 and 2, the rapidly soluble fumaric acid preparation of the present invention is superior in solubility in water as compared with the comparative product.
───────────────────────────────────────────────────── フロントページの続き (56)参考文献 特開 昭61−266496（ＪＰ，Ａ) 特公 昭46−6388（ＪＰ，Ｂ１) (58)調査した分野(Int.Cl.7，ＤＢ名) A23L 1/22 - 1/237 A23L 1/24 ──────────────────────────────────────────────────続 き Continuation of the front page (56) References JP-A-61-266496 (JP, A) JP-B-46-6388 (JP, B1) (58) Fields investigated (Int. Cl. 7 , DB name) A23L 1/22-1/237 A23L 1/24
Claims (1)
溶性界面活性剤の粉粒体とを互いに接触、衝突させてフ
マール酸を被覆してなる即溶解性フマール酸製剤。A fumaric acid preparation comprising a powdery fumaric acid and a water-soluble surfactant having a melting point of 40 ° C. or higher, which are in contact with and collided with each other to coat the fumaric acid, thereby forming a fumaric acid preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2170450A JP3022914B2 (en) | 1990-06-28 | 1990-06-28 | Fast dissolving fumaric acid preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2170450A JP3022914B2 (en) | 1990-06-28 | 1990-06-28 | Fast dissolving fumaric acid preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0458870A JPH0458870A (en) | 1992-02-25 |
| JP3022914B2 true JP3022914B2 (en) | 2000-03-21 |
Family
ID=15905158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2170450A Expired - Fee Related JP3022914B2 (en) | 1990-06-28 | 1990-06-28 | Fast dissolving fumaric acid preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3022914B2 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2796696B2 (en) * | 1994-08-22 | 1998-09-10 | 富士見工業株式会社 | Crack repair structure of concrete outer wall |
| JP2012001469A (en) * | 2010-06-16 | 2012-01-05 | Kao Corp | Method for manufacturing granulated substance for bathing agent |
-
1990
- 1990-06-28 JP JP2170450A patent/JP3022914B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0458870A (en) | 1992-02-25 |
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