JP2961587B2 - Seamless capsule particles containing surfactant - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

FIELD OF THE INVENTION The present invention relates to seamless capsule particles containing a surfactant. More specifically, the present invention relates to seamless capsule particles containing a surfactant and an oily component, which can be used in the fields of medicines, foods, luxury goods, bath products, and cleaning products.

[0002]

2. Description of the Related Art Seamless capsule particles which contain an oily component such as vegetable oil as a content and do not contain a surfactant component have conventionally existed. However, since the seamless capsule particles are produced by utilizing the interfacial tension as disclosed in Japanese Patent Publication No. 36-3700, when the internal solution contains a surfactant component having a high HLB, the content liquid and the film And the interfacial tension with the substrate considerably decreases. Therefore, encapsulation was difficult.

[0003] JP-A-61-227519 and JP-A-1-238519 disclose capsule particles containing a nonionic surfactant having a relatively high HLB. However, since these capsule particles are manufactured by filling with a capsule filling machine, there is a seam in the film, which is not only unfavorable in appearance, but also there is a concern that leakage of contents from the seam may occur, and the average film thickness may be reduced. Due to the non-uniformity,
There is a problem that the dissolution rate of each capsule particle is different. On the other hand, JP-B-53-39193 and JP-A-55-99177 disclose seamless capsule particles having a multilayer structure obtained by using multiple nozzles. It is not a capsule particle having a component as a content. Further, Japanese Patent Application Laid-Open No. 3-52639 discloses a seamless capsule in which a lower fatty acid ester of sucrose having surface activity is interposed between a content, which is a hydrophilic substance, and a film. However, it does not disclose capsule particles containing a surfactant component and an oil component as contents.

Further, Japanese Patent Application Laid-Open No. 58-13508 discloses a seamless capsule made of a drug composition containing a drug insoluble in water and a polyglycerol fatty acid ester dispersed in a liquid oil. Japanese Patent Application Laid-Open No. Hei 5-31352 discloses a seamless capsule containing a hydrophilic substance as a content and a method for producing the same. However, since the contents of these capsules do not have sufficient emulsifying properties in water, for example, when the capsules are used for applications requiring application to water such as bath salts, the oily components are separated from water, so that the oily components are separated. Is insufficiently adsorbed on the skin, and there is a problem that the expression of its function is reduced. In other words, these publications describe capsule particles in which the content liquid in the capsule is substantially emulsified and dispersed in water, or capsule particles in which the surfactant component is substantially uniformly dispersed or dissolved in the oil component. No disclosure was made.

[0005]

SUMMARY OF THE INVENTION As described above, seamless capsule particles containing a surfactant component and an oily component as a content liquid, and the emulsification and dispersibility of the content liquid,
Or, those having excellent dispersibility / solubility of the surfactant component in the oil component have not been known yet, but particularly in the fields of bath products and cleaning products, the emulsification and dispersibility of the content liquid is required. Thus, development of such seamless capsule particles has been desired. An object of the present invention is to solve the above-mentioned problem, the film is seamless, and contains a surfactant component and an oily component, and further has an emulsifying dispersibility of the content liquid as described above, or an oily component of the surfactant component. An object of the present invention is to provide capsule particles excellent in dispersibility and solubility in the inside.

[0006]

That is, the gist of the present invention is to provide (1) capsule particles comprising an inner layer and an outer layer having a film-forming body, wherein the inner layer has an anionic surfactant,
Nonionic Field of On-Surface Surfactants and HLBs 9-18
One or more surfactants selected from the group consisting of surfactants
Component and an oily component, and the emulsifying property of the content liquid of the capsule particles is such that 0.5 g of the content liquid is added to 2.5 liters of 40 ° C.
And then stirred at 40 ° C. under the following conditions at 40 ° C., wherein the oily component of the inner layer is in a state of being substantially dispersed in water while being emulsified and dispersed. Containing seamless capsule particles, stirring conditions; Container: 3 liter beaker (beaker inner diameter 14 cm,
Stirring blade: Anchor blade (wing diameter 5 cm, blade height 5 cm, blade width 1 cm) Blade position: Upper surface of blade is lower than 1 cm below water surface Rotation speed of blade: 150 rpm Stirring time: 30 seconds (2) Single a capsule particles comprising a layer having an inner layer and the film formation of layers, the inner layer is anionic
Agents, cationic surfactants and HLB 9-18
At least one field selected from the group consisting of ionic surfactants
(3) surfactant-containing seamless capsule particles comprising a surfactant component and an oily component, wherein the surfactant component is substantially uniformly dispersed or dissolved in the oily component; In the capsule particles having an inner layer having a concentric layer structure of two or more layers and having a film-forming body on the outer side, an anion is used.
Surfactants, cationic surfactants and HLB9
Selected from the group consisting of ~ 18 nonionic surfactants
The present invention relates to seamless surfactant-containing capsule particles containing one or more surfactant components and having any one of the following structures (A) to (D). (A) at least one or more layers in the inner layer comprises an aqueous dispersion containing an oil component and a surfactant component; (B) at least one or more layers in the inner layer have an oil component and a surfactant. (C) at least one layer in the inner layer comprises an oil component and a surfactant component, and (D) at least one layer in the inner layer. The above layers consist of a surfactant component.

[0007] Seamless surfactant-containing capsule particles of the present invention (hereinafter sometimes simply referred to as capsule particles)
Are capsule particles composed of an inner layer and an outer layer. The outer layer has a film forming body, and the inner layer is composed of a single layer or two or more concentric layers, and each layer is composed of (1) a layer composed of an aqueous dispersion containing an oil component and a surfactant component, (2) A layer composed of an aqueous dispersion containing an oil component, a surfactant component and a hydrophilic organic solvent, (3) a layer composed of an oil component and a surfactant component, (4) a layer of an oil component, and (5) an interface It is formed by appropriately combining layers of activator components and the like.

[0008] That is, the capsule particles of the present invention include the following various embodiments. (A) Capsule particles comprising an inner layer of a single layer and an outer layer having a film-forming body, wherein the inner layer comprises an aqueous dispersion containing an oil component and a surfactant component; Capsule particles comprising an inner layer and an outer layer having a film former, wherein the inner layer comprises an oil component and a surfactant component, and (c) an outer layer having two or more concentric inner layers and a film former. (D) two or more concentric inner layers, wherein at least one or more layers in the inner layer comprises an aqueous dispersion containing an oil component and a surfactant component. Capsule particles comprising an outer layer having a film-forming body, wherein at least one or more layers in the inner layer comprises an aqueous dispersion containing an oil component, a surfactant component, and a hydrophilic organic solvent, (E) Concentric 2
(F) When at least one or more layers in the inner layer comprises an oil component and a surfactant component, (f) concentric 2 Capsule particles comprising at least one inner layer and an outer layer having a film-forming body, wherein at least one or more of the inner layers comprises a surfactant component.

With respect to capsule particles comprising two or more concentric inner layers and an outer layer having a film-forming body,
This will be described more specifically. For example, as the capsule particles of the three layers of the inner layer and the outer layer including the intermediate layer and the innermost layer, there are various examples as shown below (indicating the outer layer / the inner layer (intermediate layer) / the inner layer (the innermost layer), respectively). . Hydrophilic film former / oil component / aqueous dispersion containing surfactant / oil component Hydrophilic film former / oil component / aqueous dispersion containing surfactant / oil component / organic solvent Hydrophilic film former / oil component / Surfactant / oil component Hydrophilic film former / oil component / surfactant Lipophilic film former / aqueous component / surfactant / oil component Lipophilic film former / surfactant / oil component Lipophilic film former / Aqueous dispersion containing surfactant / oil component / oil-based component Lipophilic film-forming product / Aqueous dispersion containing surfactant / oil component / organic solvent / oil component

Hereinafter, the constituent components of each layer constituting the capsule particles of the present invention will be described. First, the outer layer is a layer having a film-forming body, and the film-forming liquid used to form the film-forming body is a solution containing the film-forming body or a solution containing the film-forming body. The film-forming body is not particularly limited as long as it is a substance that is hardened or gelled by physical means such as cooling or chemical means such as a crosslinking reaction, and any of hydrophilic and lipophilic substances may be used. However, when used as a bath product (for example, a bath additive) or a cleaning product (for example, a body cleanser),
Natural, semi-synthetic or synthetic hydrophilic polymers having high affinity for water are preferably used.

Examples of such a hydrophilic polymer include glue, gelatin, collagen protein, casein,
Sodium alginate, carrageenan, furceleran, tamarind gum, pectin, gum arabic, guar gum, xanthan gum, tragacanth gum, locust bean gum, agar, starch and other natural hydrophilic polymers; carboxymethylcellulose, methylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, phthalate acetate Semi-synthetic hydrophilic polymers such as cellulose acetate, propylene glycol alginate, oxidized starch, esterified starch, etherified starch, and cationic starch; and synthesis of sodium polyacrylate, polyethylene imine, polyvinyl alcohol, polyethylene oxide, polyvinyl pyrrolidone, etc. Examples include, but are not limited to, hydrophilic polymers. These hydrophilic polymers are used alone or in combination of two or more. When a solution containing a film-forming body is used as the film-forming liquid, a hydrophilic polymer is used as the film-forming body, and 0.1 to 80% by weight.
Is preferable, and more preferably a solution of 1 to 50% by weight. Although the solvent is not particularly limited, water is preferred.

At this time, one or more water-soluble polyhydric alcohols and derivatives thereof may be added together with the above-mentioned hydrophilic polymer. When a water-soluble polyhydric alcohol and its derivative are added, usually 5
To 100% by weight, preferably 10 to 80% by weight. Examples of the water-soluble polyhydric alcohol and its derivative to be added include glycerin, sorbitol, ethylene glycol, polyethylene glycol, propylene glycol, polypropylene glycol, ethylene oxide-propylene oxide copolymer, oligosaccharides, glycerides and the like. However, the present invention is not particularly limited to these. In the present invention, a lipophilic film-forming body can be used in the same manner, for example, polystyrene, polymethyl methacrylate, polybutadiene, styrene-butadiene rubber, vinyl acetate-ethylene copolymer, vinylidene chloride-acrylonitrile copolymer, A styrene-acrylate copolymer, ethyl cellulose, or the like can be used alone or as a mixture of two or more. When a solution containing a lipophilic film-forming body is used as the film-forming liquid, the solvent is not particularly limited as long as it is a good solvent for the film-forming body, and may be dichloromethane, chloroform, carbon tetrachloride, benzene, or the like. Is exemplified.

The inner layer is a layer containing an oil component and a surfactant component, and is composed of a single layer or two or more concentric layers. As described above, each layer is composed of a layer comprising an aqueous dispersion containing (1) an oil component and a surfactant component, and (2) an aqueous dispersion containing an oil component, a surfactant component and a hydrophilic organic solvent. And (3) a layer composed of an oil component and a surfactant component, (4) a layer composed of an oil component, and (5) a layer composed of a surfactant component. The surfactant used herein is selected from one or more of an anionic surfactant, a cationic surfactant, a nonionic surfactant and an amphoteric surfactant. A surfactant having high solubility is suitably selected. When two or more surfactants are used, even if they have low solubility in oil, they only need to be mixed and have solubility as a whole.
In the case where the inner solution comes into contact with the skin after the capsule particles are disintegrated, for example, one selected from one or more nonionic surfactants having less skin irritation is preferable.

The anionic surfactant is not particularly restricted but includes, for example, sodium lauryl sulfate,
Triethanolamine lauryl sulfate, ammonium lauryl sulfate, sodium dodecylbenzenesulfonate,
Sodium stearate, semi-hardened beef fatty acid sodium,
Semi-hardened beef fatty acid potassium, potassium oleate, castor oil potassium, sodium alkylnaphthalene sulfonate,
Sodium dialkyl sulfosuccinate, sodium alkyl diphenyl ether disulfonate, diethanolamine alkyl phosphate, potassium alkyl phosphate, sodium polyoxyethylene alkyl sulfate, triethanolamine polyoxyethylene alkyl ether sulfate, sodium polyoxyethylene alkyl phenyl ether sulfate, and the like. Can be

The cationic surfactant is not particularly restricted but includes, for example, lauryltrimethylammonium chloride, stearyltrimethylammonium chloride, cetyltrimethylammonium chloride, distearyldimethylammonium chloride, alkylbenzenedimethylammonium chloride, stearylamine oleate. , Stearylamine acetate, stearylamine acid and the like.

The nonionic surfactant is not particularly restricted but includes, for example, glycerin fatty acid ester, propylene glycol fatty acid ester, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, propylene fatty acid ester, glycerin fatty acid ester, Sugar fatty acid ester, polyoxyethylene sorbitol fatty acid ester, polyoxyethylene sorbite tetraoleate, polyoxyethylene alkyl ether, polyoxypropylene alkyl ether,
Polyoxyethylene polyoxypropylene glycol,
Polyoxyethylene polyoxypropylene alkyl ether, polyethylene glycol fatty acid ester, polyoxyethylene castor oil, polyoxyethylene hardened castor oil, and the like. Among these, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, and polyoxyethylene sorbitol fatty acid esters are preferred because of their low skin irritation.

The amphoteric surfactant is not particularly restricted but includes, for example, betaine alkyldimethylaminoacetate, alkyldimethylamine oxide, alkylcarboxymethylhydroxyethylimidazolium betaine, lecithin, laurylaminopropionic acid, alkyldiaminoethylglycine. And the like.

The HLB of the nonionic surfactant for seamless encapsulation is usually from 7 to 7 in order that the oily component of the contents can be emulsified well when the capsule particles disintegrate in a water bath. 18, preferably 8 to 1
8, more preferably 9 to 18. When the HLB is less than 7, the emulsifying ability of the oily component is insufficient, and when the HLB is more than 18, encapsulation becomes difficult. When two or more nonionic surfactants are mixed, the HLB after mixing is 7 to 1
A nonionic surfactant having an HLB of less than 7 may be similarly mixed in order to adjust the HLB in the capsule particles. The capsule particles of the present invention are manufactured by continuously discharging a liquid for forming each layer using multiple nozzles as described later.
The nonionic surfactant having B of less than 7 may be mixed with any of the liquids for the inner layer.

The amount of the surfactant used is not particularly limited, but is usually from 49: 1 to 1: 3, preferably from 1 to 1 by weight, based on the weight ratio of the total oil component and the surfactant in the capsule particles.
9: 1 to 1.5: 1. When the amount of the surfactant used is less than 49: 1 in weight ratio to the total oil component, when the internal solution comes into contact with water, the oil component separates to cause a phenomenon such as oil floating and a stable emulsion is obtained. 1: 3
If it is larger, encapsulation becomes difficult.

The oily component used in the present invention is not particularly limited. Examples thereof include oils and fats, waxes, hydrocarbons, higher fatty acids, higher alcohols, esters, essential oils, and silicone oils. One or more selected mixtures are preferred.

As fats and oils, for example, soybean oil, bran oil,
Jojoba oil, avocado oil, almond oil, olive oil, cacao butter, sesame oil, persic oil, castor oil, coconut oil, mink oil, tallow, lard, and other natural fats and oils, or cured products obtained by hydrogenating these natural fats and oils Examples include oil and synthetic triglycerides such as myristic glyceride and 2-ethylhexanoic acid glyceride. Examples of the waxes include carnauba wax, whale wax, beeswax, and lanolin. Examples of the hydrocarbons include liquid paraffin,
Vaseline, paraffin microcrystalline wax,
Ceresin, squalane, pristane and the like. Examples of higher fatty acids include lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, linoleic acid, linolenic acid, lanolinic acid, isostearic acid and the like. As higher alcohols,
Examples include lauryl alcohol, cetyl alcohol, stearyl alcohol, oleyl alcohol, lanolin alcohol, cholesterol, 2-hexyldecanol and the like. Examples of the esters include cetyl octoate, myristyl lactate, cetyl lactate, isopropyl myristate, myristyl myristate, isopropyl palmitate, isopropyl adipate, butyl stearate, decyl oleate, and the like. As essential oils, for example, mint oil, jasmine oil, show brain oil, hinoki oil, spruce oil, ryu oil, turpentine oil, cinnamon oil, helgamot oil, tangerine oil, show oil, pine oil, lavender oil, bay oil, Clove oil, hiba oil, rose oil, eucalyptus oil, lemon oil, peppermint oil, rose oil, sage oil, menthol, cineole, eugenol, citral, citronellal, borneol, linalool, gellarol, camphor, thymol, spiranthol, pinene, limonene And terpel compounds. Examples of silicone oils include, but are not limited to, dimethylpolysiloxane and the like.

In the present invention, in the case of forming a layer composed of an aqueous dispersion containing (1) an oil component and a surfactant component, the aqueous dispersion contains one or a mixture of two or more oil components. Emulsifying an oily component directly in water with one or more surfactants selected from the group consisting of anionic surfactants, cationic surfactants, nonionic surfactants, and amphoteric surfactants as described above. Or by a known technique such as emulsification of an oily component in water through a phase inversion from a water-in-oil emulsion to an oil-in-water emulsion. As the emulsification method, a known technique using various stirrers, mixers and the like is used. The concentration of the surfactant in the aqueous dispersion is not particularly limited, but is usually from 10 to 300% by weight, preferably from 50 to 250% by weight, based on the oil component in the aqueous dispersion. When the surfactant concentration is less than 10% by weight, the oily component of the contents is not emulsified when the capsules are disintegrated in a water bath, and when the surfactant concentration is more than 300% by weight, the viscosity of the aqueous dispersion increases, and the capsules when forming capsule particles are formed. It is not preferable because the success rate of particle generation is reduced.

The concentration of the oily component in the aqueous dispersion is not particularly limited, but is usually 2 to 150% by weight, preferably 5 to 130% by weight based on water. When the concentration of the oil component is more than 150% by weight, the viscosity of the aqueous dispersion increases, and the formability of the capsule particles at the time of forming the capsule particles is reduced. Thus, when the concentration is less than 2% by weight, a uniform aqueous dispersion cannot be obtained. Therefore, it is not preferable.

In the present invention, as a mode of (2), a layer comprising an aqueous dispersion in which a hydrophilic organic solvent is contained in the aqueous dispersion of (1) may be used. Thereby, the viscosity of the aqueous dispersion can be reduced, and particularly when the concentration of the surfactant in the aqueous dispersion is high, the formability of capsule particles at the time of capsule formation is improved. Although the hydrophilic organic solvent used at this time is not particularly limited, for example, methanol, ethanol, 1-propanol, 2-
Monohydric alcohols such as propanol, dihydric alcohols such as ethylene glycol, 1,2-propanediol, 1,3-butanediol, and 1,5-pentanediol;
It is selected from ketones such as acetone and the like, and may be used alone or in combination of two or more. Here, the concentration of the hydrophilic organic solvent in the aqueous dispersion is not particularly limited, but is usually 0.01 to 200% by weight, preferably 0.1 to 100% by weight based on water. The amount of the hydrophilic organic solvent is 0.
If it is less than 01% by weight, the effect of lowering the viscosity of the aqueous dispersion by the addition of the hydrophilic organic solvent is small, and if it is more than 200% by weight, the interfacial tension of the aqueous dispersion becomes too low, and the aqueous dispersion becomes spherical. As a result, the success rate at the time of capsule generation decreases, which is not preferable.

Next, (3) When forming a layer composed of an oil component and a surfactant component, the same surfactant component and oil component as described above are used. The concentration of the oil component in this case is not particularly limited, but is 0.01 to 300% by weight, preferably 0.1 to 300% by weight based on the surfactant component.
~ 200% by weight. When the amount of the oil component is less than 0.01% by weight, the effect of addition such as a change in viscosity is small,
When the content is more than 0% by weight, when the inner solution comes into contact with water, oily components are separated and a phenomenon such as oil floating occurs, and a stable emulsion is not obtained, which is not preferable.

Further, when forming the layer of (4) the oil component and the layer of (5) the surfactant component, the types of the oil component and the surfactant component used are the same as those described above.

The capsule particles of the present invention can be obtained by discharging each liquid for forming each layer from multiple nozzles to form multilayer droplets as described later. At this time, the total liquid flow rate,
The particle size of the capsule particles can be controlled by the viscosity of the liquid, the interfacial tension of the liquid, the frequency, and the like. Furthermore, if the particle size of the capsule particles is determined, the average coating thickness can be controlled by the flow ratio of the flow rate of the outermost nozzle to the total flow rate of the other nozzles. The average film thickness t at this time
Can be obtained, for example, from the following equation.

[0028]

(Equation 1)

T: Average coating thickness [cm] D: Capsule particle average particle diameter [cm] D ₁ : Capsule particle average inner layer diameter [cm] V ₁ : Capsule particle inner layer volume [cm ³ ] = W ₁ / ρ ₁ =
Q ₁ / IV ₂ : Capsule particle coating volume [cm ³ ] = W ₂ / ρ ₂ =
Q ₂ / I W ₁ : Capsule particle inner layer weight [g] W ₂ : Capsule particle coating weight [g] Q ₁ : Total flow rate of inner layer liquid from nozzle [cm ³ / min] Q ₂ : For film formation from nozzle Total flow of liquid [cm ³ /
min] ρ ₁ : Average density of inner layer liquid [g / cm ³ ] ρ ₂ : Density of film forming liquid [g / cm ³ ] I: Number of capsule particles generated [pcs / min]

In the present invention, the film ratio, which is the weight ratio of the film to the weight of the capsule particles, is usually 5 to 60% by weight, preferably 5 to 60% by weight, from the viewpoint of the storage stability of the capsule particles and the disintegration of the capsule particles in water such as in a bathtub. It is 10 to 50% by weight, more preferably 13 to 40% by weight. If the coating rate is less than 5% by weight, the capsule particles are easily disintegrated during storage, and if it exceeds 60% by weight, the disintegration and complete solubility of the capsule particles in water such as in a bathtub become poor.

The average particle diameter of the capsule particles of the present invention is not particularly limited, but is generally preferably 0.2 mm to 2 cm, and from the viewpoint of productivity, preferably 3 mm to 2 cm.
cm. The reason for this is that, for example, when capsule particles are produced using a multiple nozzle described later, the larger the average particle diameter, the higher the production capacity per multiple nozzle. However, the average particle size is shown by weight average. The average coating thickness of the capsule particles is not particularly limited, but is usually in the range of 0.01 mm to 5 mm, preferably 0.03 mm to 1 mm. 5
When the diameter is larger than 0 mm, when dissolving the capsule to release the contents, a long dissolution time is required, which is not preferable.
When the thickness is 1 mm or less, the film-forming body is easily disintegrated at the time of capsule particle formation, and the success rate of capsule formation is significantly reduced. The average film thickness referred to here is a value measured by a known measuring technique, for example, a micrometer or the like.

The capsule particles of the present invention are excellent in emulsifying properties and have emulsifying properties based on the following emulsifying properties test. That is, the content liquid of the capsule particles 0.
5 g was poured into 2.5 liters of 40 ° C. water and stirred under the following conditions to emulsify and disperse the oily component of the inner layer.
At 0 ° C., preferably after standing at 40 ° C. for 3 hours, more preferably after standing for 6 hours, particularly preferably when the state of emulsification after standing for 12 hours is visually observed, there is almost no separation of the emulsified phase, It has an emulsifying property that is not substantially separated from water. Stirring conditions; Container: 3 liter beaker (beaker inner diameter 14 cm,
Stirring blade: anchor blade (wing diameter: 5 cm, blade height: 5 cm, blade width: 1 cm) Blade position: upper surface of blade is lower than 1 cm below water surface Rotation speed of blade: 150 rpm Stirring time: 30 seconds Therefore, the present invention In the said, the oily component is not substantially separated from water while being emulsified and dispersed, in such an emulsification test, there is almost no separation of an emulsified phase, a state in which an aqueous phase is not formed, or an oily component or an oily component. A state in which a mixture with a surfactant component is released from an emulsified dispersion and does not exist in water as oil droplets. The capsule particles of the present invention are those in which the surfactant component contained in the inner layer is substantially uniformly dispersed or dissolved in the oil component.
This is done by taking out the content liquid of the capsule particles,
Is transferred to a test tube and left in an atmosphere of 25 ° C. and 60% humidity for 6 hours, in which the oil component and the surfactant component are not separated.

Next, the method for producing the surfactant-containing seamless capsule particles according to the present invention using the above-mentioned various raw materials will be described in detail. The capsule particles of the present invention, by using at least three or more types of multi-nozzles having a sequentially increasing diameter, continuously discharge the film-forming liquid from the outermost nozzle and the various inner-layer liquids from the other nozzles. After forming the multi-layer droplets, the film-forming liquid of the multi-layer droplets is cured or gelled.

As the liquid of each layer forming the inner layer, as the liquid flowing from a nozzle other than the nozzle for flowing the liquid containing the surfactant component, an oil component and an aqueous component are appropriately selected within a range that does not hinder the encapsulation. You. That is, as the components contained in the layers adjacent to each other, components that do not substantially mix (dissolve) with each other or components that are difficult to mix (dissolve), such as an oil component and an aqueous component, are appropriately selected. In this case, the same oily component as described above is used, and as the aqueous component, water, an aqueous acetone solution, an aqueous lower alcohol solution, or the like is used.

FIG. 1 is a cross-sectional view schematically showing one example of a nozzle portion of a manufacturing apparatus used in the manufacturing method according to the present invention. In this figure, a triple nozzle having the same discharge port end face is illustrated. However, in the present invention, the shape and the like are particularly limited as long as the multiple nozzle has at least three or more nozzles having a sequentially increasing diameter. However, the end surfaces of the nozzles may not be aligned in this manner.

In the present invention, using such a triple nozzle, the above-mentioned film-forming liquid is supplied from the outermost nozzle inlet 4, the oil component is supplied from the intermediate nozzle inlet 5, and the surfactant component is supplied. The liquid containing is supplied from the innermost nozzle inlet 6, and each liquid is continuously discharged from the outermost nozzle 3, the intermediate nozzle 2, and the innermost nozzle 1 in the gas phase or the liquid phase, respectively, to generate multilayer droplets. . In this case, the liquid phase is not particularly limited as long as it does not substantially mix or dissolve with the film-forming body. However, a hardening agent or a gelling agent as described below is preferably used in production. Next, the film-forming liquid of the multilayer droplets is cured or gelled by physical or chemical means to produce surfactant-containing seamless capsule particles. Here, physical methods include, for example, a method in which a film-forming liquid is brought into contact with a cooled hardener to cool the film-forming liquid, and curing is performed, and chemical methods include a gel formed by a chemical reaction between the film-forming liquid and the hardening agent. For example, a method of hardening or gelling the film-forming liquid is not limited thereto.

The curing agent is not particularly limited as long as it is a liquid that cures or gels the film-forming liquid by physical or chemical means. A substance having substantially no solubility in the film-forming body obtained by the above method is appropriately used. For example, for a hydrophilic film-forming body, one or a mixture of two or more kinds selected from oils and fats, waxes, hydrocarbons, higher fatty acids, higher alcohols, esters, essential oils, and silicone oils. Oils are used, and water, methanol, ethanol, 1-propanol, 2-propanol, and mixtures thereof are used for the lipophilic film-forming body. The cooling temperature is not particularly limited as long as the film-forming liquid is cured.

When the film-forming liquid is chemically gelled, for example, a solution containing calcium chloride and calcium phosphate for sodium alginate, an aqueous solution containing borax, formalin and hydrochloric acid for polyvinyl alcohol,
As gelatin, an aqueous solution containing calcium chloride and zirconium nitrate is appropriately selected, and gelation occurs due to a reaction such as crosslinking between the film forming liquid and these hardeners.

By these methods, it is possible to obtain capsule particles having a layer structure of two or more concentric inner layers.
In the present invention, as described above, each liquid is continuously discharged from each nozzle of the multi-nozzle to form a multi-layer droplet, but by applying vibration to the multi-layer liquid column discharged from the multi-nozzle at this time, The particle size of the capsule particles, the thickness of the coating, and the like can be made more uniform. At this time, a known vibration imparting means is used, but the method of imparting the vibration is not particularly limited, either, the nozzle is vibrated, or the liquid flowing into the nozzle is given a pulsating flow, or the liquid is ejected from the nozzle. A method of giving vibration to the external phase of the multilayer liquid column is exemplified. The frequency given to the multi-layer liquid column is appropriately selected from the liquid column linear velocity and the liquid viscosity used, and the particle size of the capsule particles can be controlled by the relationship between these, the frequency, the discharge flow rate from the nozzle, and the like. is there. The frequency to be applied is not particularly limited, but in terms of productivity of the capsule particles and uniformity of the particle diameter of the capsule particles, 1 to 3000 Hz,
Preferably 1 to 2000 Hz, particularly preferably 1 to 10 Hz
00 Hz. If it is less than 1 Hz, the vibration is not sufficient, and if it exceeds 3000 Hz, the particle size of the capsule particles becomes non-uniform. In the present invention, a method for obtaining a droplet without applying vibration is also selected.

In the present invention, among the linear velocities of the liquid discharged from each of the multiple nozzles, the maximum linear velocity is preferably 1.0 to 1.3 times the minimum linear velocity.
More preferably 1.0 to 1.1 times, and still more preferably 1.
It is 0 to 1.05 times. As described above, when the ratio of the linear velocities is 1.0 to 1.3 times, concentric capsule particles are easily generated, and a film having a uniform film thickness can be obtained. Further, in order to produce capsule particles containing a large amount of the content liquid, the diameter of each nozzle is appropriately selected so that the ratio of the linear velocities of the liquids discharged from the respective nozzles is within the above range. Can be produced stably. Furthermore, when manufacturing capsule particles with small interfacial tension, capsule particles are easily generated. On the other hand, when the multilayer liquid column is vibrated to generate capsule particles, the success rate of encapsulation becomes higher.

In order to form the capsule particles of the present invention in which the inner layer has a single layer, the capsule particles having the above-obtained inner layer having a concentric two or more layer structure are dried. Thereby, each of the inner layers can be integrated into a single layer. As another method, for example, an oily component and a surfactant are discharged from the innermost nozzle, an oily component having a melting point near room temperature is discharged from the intermediate nozzle, and a film-forming liquid is discharged from the outermost nozzle. Capsule particles having a single inner layer can also be produced by chemically gelling the film-formed body and then subjecting it to a heat treatment. In addition, in the present invention, when the physical properties such as fluidity and non-caking properties of the capsule particles are deteriorated due to the interaction between the water in the capsule particles and the film forming body, the capsule particles are dried to remove the water in the particles. It is also possible to remove it. As a method for drying the capsule particles in the present invention,
Known drying methods such as a hot air drying method, a vacuum drying method, and a freeze drying method can be used, and the moisture concentration in the particles can be adjusted as necessary. Can also. In the present invention, the water concentration is usually 25% by weight or less, preferably 20% by weight or less, more preferably 15% by weight or less. If it exceeds 25% by weight, the adhesiveness of the particle surface is so high that it is not preferable when used as dry particles.

The surfactant-containing seamless capsule particles obtained according to the present invention can be used in the fields of medicines, foods, luxury articles, bath articles, and cleaning articles. Further, useful components, additives, and the like are appropriately blended according to various uses, and can be used in these fields as surfactant-containing seamless capsule particles having various functions.

[0043]

The present invention will be described in more detail with reference to the following examples and comparative examples, but the present invention is not limited to these examples. FIG. 1 is a sectional view schematically showing a nozzle portion of a triple nozzle having a sequentially increasing diameter used in the following embodiments.

Example 1 A triple nozzle having a sequentially increasing diameter [inner nozzle diameter 0.9 mm, intermediate nozzle diameter 2 mm, outermost nozzle diameter 3.5]
mm], 6% by weight of tri (caprylic capric acid) glycerin (manufactured by Coconado Kao Corporation) and 12.6% by weight of polyoxyethylene (average number of moles added: 20) sorbitan trioleate [HLB : 1
1], 1.4% by weight of sorbitan sesquioleate [HL
B: 3.7] (average HLB: 10.3), and water (80% by weight) was added thereto, and the obtained aqueous dispersion was flowed through the innermost nozzle at a flow rate of 2.2 [g / min]. Tri (caprylic capric acid) glycerin was flowed from the intermediate nozzle at a flow rate of 4.4 g / min.
An aqueous solution containing 70% by weight of glycerin, 4% by weight of glycerin, and 66% by weight of water is discharged simultaneously into the gas phase at a flow rate of 5.8 [g / min] at a flow rate of 5.8 [g / min] to form multilayer droplets and cooled to 2 ° C By dropping into the liquid paraffin thus obtained, capsule particles having a weight ratio of the surfactant to the oil component of 1: 4 in the particles were obtained. The inner layer of the capsule particles comprises two concentric layers,
The innermost layer was an aqueous dispersion containing an oily component and a surfactant component, the intermediate layer was an oily component, and was a surfactant-containing seamless capsule particle having a film-forming body in the outermost layer. When the particle diameter D of the capsule particles was measured with a vernier caliper, the average particle diameter was 5.1 mm, and the variation coefficient of the particle diameter distribution was 6.3%. The average film thickness t was 1.5 mm when measured with a micrometer. The coating ratio was 41.7% by weight.

Example 2 The surfactant-containing seamless capsule particles prepared in Example 1 were cooled (4 ° C.) in liquid paraffin in a refrigerator for 12 hours, and then dried at 21 ° C. and 60% humidity for 12 hours. Thus, capsule particles having a surfactant in the particles and a weight ratio of the oil component of 1: 4 were obtained. The inner layer of the capsule particles was a single layer, and the inner layer was substantially composed of an oily component and a surfactant component, and was a seamless surfactant-containing capsule particle having a film-forming body outside thereof. When the particle diameter D of the capsule particles was measured with a vernier caliper, the average particle diameter was 3.
2 mm, and the coefficient of variation of the particle size distribution was 6.6%. The average coating thickness t was 0.29 mm when measured with a micrometer. The water content in the capsule particles was 3.5% by weight. Further, the coating ratio was 25.3% by weight.

Example 3 A triple nozzle having a sequentially increasing diameter [inner nozzle diameter 0.9 mm, intermediate nozzle diameter 2 mm, outermost nozzle diameter 3.5]
mm], glycerin tri (caprylate caprylate) 20% by weight and polyoxyethylene (average mole number 20) sorbitan trioleate 72% by weight [HLB: 11], sorbitan sesquioleate 8% by weight [HLB: 3.7] mixture [average HLB: 10.
3] at a flow rate of 0.2 g / min from the innermost nozzle, tri (caprylate capric acid) glycerin at a flow rate of 0.6 g / min from the intermediate nozzle, and 30% by weight of gelatin from the outermost nozzle. Glycerin 4% by weight, water 66% by weight
Of the aqueous solution maintained at 70 ° C. at a flow rate of 1.1 g / min.
And simultaneously discharge into the gas phase to generate multilayer droplets,
By dropping into liquid paraffin cooled to ° C., capsule particles having a surfactant in the particles and a weight ratio of the oil component of 1: 4 were obtained. The inner layer of the capsule particles is composed of two concentric layers, the innermost layer is composed of an oil component and a surfactant component, the intermediate layer is composed of an oil component, and the outermost layer has a surfactant-containing seam having a film-forming body. There were no capsule particles. When the particle size D of the capsule particles was measured with a vernier caliper, the average particle size was 4.8 mm, and the variation coefficient of the particle size distribution was 7.2%. The average coating thickness t was 0.9 mm when measured with a micrometer. Also,
The coating ratio was 57.9% by weight.

Example 4 A triple nozzle having a sequentially increasing diameter [inner nozzle diameter 0.9 mm, intermediate nozzle diameter 2 mm, outermost nozzle diameter 3.5]
mm], sorbitan trioleate 90% by weight [HLB: 11], sorbitan sesquioleate 10
Wt% [HLB: 3.7] mixture [average HLB: 1]
0.3] to 40 ° C and a flow rate of 0.3 g from the innermost nozzle.
/ Min] and tri (caprylate capric acid) glycerin from the intermediate nozzle at a flow rate of 1.2 [g / min].
From the outermost nozzle, an aqueous solution of 30% by weight of gelatin, 4% by weight of glycerin and 66% by weight of water maintained at 70 ° C. at a flow rate of 1.8.
[G / min] at the same time to discharge into the gas phase to produce multilayer droplets, which are dropped onto liquid paraffin cooled to 2 ° C., so that the weight ratio of the surfactant in the particles to the oil component is 1 : 4 were obtained. The inner layer of the capsule particles is composed of two concentric layers, the innermost layer is composed of a surfactant component, the intermediate layer is an oily component and the outermost layer is a surfactant-containing seamless capsule particle having a film-forming body. Was. When the particle size D of the capsule particles was measured with a vernier caliper, the average particle size was 4.6 mm, and the variation coefficient of the particle size distribution was 8.0%. The average coating thickness t was 0.9 mm when measured with a micrometer. Further, the coating ratio was 54.6% by weight.

Example 5 A triple nozzle having a sequentially increasing diameter [inner nozzle diameter 0.9 mm, intermediate nozzle diameter 2 mm, outermost nozzle diameter 3.5]
mm], 6% by weight of tri (caprylic capric acid) glycerin (manufactured by Coconado Kao Corporation) and 12.6% by weight of polyoxyethylene (average number of moles added: 20) sorbitan trioleate [HLB : 1
1], 1.4% by weight of sorbitan sesquioleate [HL
B: 3.7], [average HLB: 10.3], 70% by weight of water was added thereto and stirred to obtain an aqueous dispersion, and 10% by weight of ethanol was added to the mixture to contain a hydrophilic organic solvent. The flow rate of the aqueous dispersion from the innermost nozzle is 2.2 g / min.
And from the middle nozzle, tri (caprylic capric acid)
Glycerin was supplied at a flow rate of 4.4 [g / min] from the outermost nozzle with 30% by weight of gelatin, 4% by weight of glycerin, and 66% of water.
The aqueous solution maintained at 70 ° C. at a flow rate of 5.8 g / mi
n], the droplets are simultaneously discharged into the gas phase to form multilayer droplets, and the droplets are dropped on liquid paraffin cooled to 2 ° C., so that the weight ratio of the surfactant to the oil component in the particles is 1:
4 capsule particles were obtained. The inner layer of the capsule particles is composed of two concentric layers, the innermost layer is an aqueous dispersion containing an oil component, a surfactant component, and a hydrophilic organic solvent, the intermediate layer is formed of an oil component, and the outermost layer is formed. These were surfactant-containing seamless capsule particles having a film former. When the particle diameter D of the capsule particles was measured with a vernier caliper, the average particle diameter was 5.2 mm, and the variation coefficient of the particle diameter distribution was 6.
1%. The average film thickness t was 1.5 mm when measured with a micrometer. The coating rate is 4
It was 1.7% by weight.

Example 6 A triple nozzle having a sequentially increasing diameter [inner nozzle diameter 0.9 mm, intermediate nozzle diameter 2 mm, outermost nozzle diameter 3.5]
mm], 6% by weight of tri (caprylic capric acid) glycerin (manufactured by Coconado Kao Corporation) and 12.6% by weight of polyoxyethylene (average number of moles added: 20) sorbitan trioleate [HLB : 1
1], 1.4% by weight of sorbitan sesquioleate [HL
B: 3.7] (average HLB: 10.3), 70% by weight of water was added thereto, and the mixture was stirred to obtain an aqueous dispersion. The flow rate of the dispersion is 4.4 g / min from the innermost nozzle.
And from the middle nozzle, tri (caprylic capric acid)
Glycerin was supplied at a flow rate of 8.8 [g / min] from the outermost nozzle with 30% by weight of gelatin, 4% by weight of glycerin, and 66% of water.
Weight% aqueous solution maintained at 70 ° C. at a flow rate of 11.6 g / m 2
In], the nozzle is ejected into the gas phase while applying a vibration of 10 Hz to form a multi-layer droplet, and the droplet is dropped on liquid paraffin cooled to 2 ° C., whereby the amount of the surfactant and the weight of the oil component in the particle are reduced. Capsule particles having a ratio of 1: 4 were obtained.
The inner layer of the capsule particles is composed of two concentric layers, the innermost layer is an aqueous dispersion containing an oily component and a surfactant component, the intermediate layer is composed of an oily component, and the outermost layer has a film-forming body. It was a seamless capsule particle containing surfactant. When the particle size D of the capsule particles was measured with a vernier caliper, the average particle size was 4.5 mm, and the variation coefficient of the particle size distribution was 4.8%. The average coating thickness t was 0.3 mm when measured with a micrometer. The coating ratio was 41.7% by weight.

Example 7 A triple nozzle having a sequentially increasing diameter [inner nozzle diameter 0.9 mm, intermediate nozzle diameter 2 mm, outermost nozzle diameter 3.5]
mm], 6% by weight of tri (caprylic capric acid) glycerin (manufactured by Coconado Kao Corporation) and 12.6% by weight of polyoxyethylene (average number of moles added: 20) sorbitan trioleate [HLB : 1
1], 1.4% by weight of sorbitan sesquioleate [HL
B: 3.7] (average HLB: 10.3), and an aqueous dispersion in which 80% by weight of water was charged was flowed from the innermost nozzle at a flow rate of 2.2 g / min. Tri (caprylic capric acid) glycerin was supplied at a flow rate of 4.4 g.
/ Min] at a flow rate of 5.8 [g / min] with an aqueous solution of 0.8% by weight of sodium alginate from the outermost nozzle.
Simultaneously, the mixture was discharged into the gas phase and dropped into an aqueous solution containing 3% by weight of calcium chloride, whereby capsule particles having a surfactant to oil component weight ratio of 1: 4 in the particles were obtained. The inner layer of the capsule particles is composed of two concentric layers, the innermost layer is an aqueous dispersion composed of an oil component and a surfactant component, the intermediate layer is composed of an oil component, and the outermost layer has a film-forming body. It was a seamless capsule particle containing surfactant. When the particle diameter D of the capsule particles was measured with a vernier caliper, the average particle diameter was 5.1 mm, and the variation coefficient of the particle diameter distribution was 6.4.
%Met. The average film thickness t was 1.5 mm when measured with a micrometer. The coating ratio was 41.
7% by weight.

Example 8 A triple nozzle having a sequentially increasing diameter [inner nozzle diameter 0.9 mm, intermediate nozzle diameter 2 mm, outermost nozzle diameter 3.5]
mm], tri (caprylic capric acid) glycerin was flowed at 4.4 g / m from the innermost nozzle.
in], and 6% by weight of tri (caprylic capric acid) glycerin [manufactured by Coconado MT Kao Corporation] and 12.6% by weight of polyoxyethylene (average number of moles added: 20) sorbitan trioleate [HLB: 1
1], 1.4% by weight of sorbitan sesquioleate [HL
B: 3.7] (average HLB: 10.3), and an aqueous dispersion in which 80% by weight of water was introduced was used to give a flow rate of 2.2 [g].
/ Min], 12% by weight of polystyrene from the outermost nozzle
At a flow rate of 5.8 g / min.
At the same time, the mixture was discharged into the gas phase and dropped into water to obtain capsule particles having a surfactant in the particles and a weight ratio of the oil component of 1: 4. The inner layer of the capsule particles is composed of two concentric layers, the innermost layer is an oily component, the intermediate layer is an aqueous dispersion of an oily component and a surfactant component, and the outermost layer is an interface having a film-forming body. Activator-containing seamless capsule particles. Then, an aqueous dispersion containing the capsule particles was added to 50
C., the dichloromethane in the film was removed under a reduced pressure of 100 Torr for 2 hours, and the particle diameter D was measured with a vernier caliper. The average particle diameter was 4 mm, and the variation coefficient of the particle diameter distribution was 7.8. %Met. The average coating thickness t was 0.2 mm when measured with a micrometer. Also,
The coating ratio was 7.9% by weight.

Comparative Example 1 Example 3 was repeated except that no surfactant was used.
In the same manner as described above, seamless capsule particles were obtained. When the particle diameter D of the capsule particles was measured with a vernier caliper, the average particle diameter was 5.1 mm, and the variation coefficient of the particle diameter distribution was 6.3.
%Met. The average film thickness t was uniform at 1.5 mm when measured with a micrometer. The coating rate is 41.
7% by weight.

Comparative Example 2 A double nozzle having a sequentially increasing diameter [inner nozzle inner diameter 0.6 mm outer diameter 1.0 mm, outermost nozzle inner diameter 1.5 m
m], 50 g of purified l (l) -carvone, octaglycerol monooleate (Ques)
t International's product name Sant
one 8-1-0) and 20 g of decaglycerol decaoleate (product name: Santone 10-10-0, manufactured by Quest International).
After dissolving at 0 ° C., the liquid composition cooled to 30 ° C. was supplied at a flow rate of 1.1 g / min from the innermost nozzle, and 30% by weight of gelatin, 4% by weight of glycerin, and 66% by weight of water from the outermost nozzle. An aqueous solution that had been dissolved at 70 ° C. and cooled to 45 ° C. was simultaneously discharged into the gas phase at a flow rate of 1.7 [g / min] to form multilayer droplets. By dropping, the weight ratio of the surfactant to the oil component in the particles is 7: 5, the innermost layer is composed of the oil component and the surfactant component, and the outermost layer contains the surfactant having a film-forming body. Seamless capsule particles were obtained. The capsule particles were allowed to stand for 12 hours in an atmosphere of a temperature of 5 ° C. and a humidity of 20% for 12 hours, and the particle diameter D was measured with a caliper. The average particle diameter was 4.4 mm, and the coefficient of variation of the particle diameter distribution was 15.0%.
Met. When measured with a micrometer, the film thickness t was in the range of 0.35 to 0.75 mm. The coating ratio was 43.9% by weight.

Test Example 1 An emulsifying test was carried out on the contents of the capsule particles of Examples 1 to 8 and Comparative Examples 1 and 2 as follows. FIG. 2 shows a schematic diagram of the test apparatus. That is, 0.5 g of the content liquid of the capsule particles was poured into 2.5 liters of water at 40 ° C., and stirred under the following conditions to emulsify and disperse the oil component of the inner layer. The state of emulsification after standing for 3, 6, and 12 hours was evaluated by visual observation. Stirring conditions; Container: 3 liter beaker (beaker inner diameter 14 cm,
Stirring blade: Anchor blade (wing diameter: 5 cm, blade height: 5 cm, blade width: 1 cm) Blade position: Upper surface of blade is lower than 1 cm below water surface Rotation speed of blade: 150 rpm Stirring time: 30 seconds

Here, the evaluation of the emulsifying properties was performed based on the following criteria. ：: Almost no separation of the emulsified phase or almost no oil droplets released from the emulsified phase △: Either an aqueous phase due to the separation of the emulsified phase or a free oil droplet due to the separation of the emulsified phase ×: Emulsification Little oil phase, oily components present as free oil droplets or oil phase As a result, the liquid contents in Examples 1 to 8 were emulsified and dispersed at 40 ° C. and at 40 ° C. for 3, 6, 12 hours. After placing, the oil component of the content liquid was emulsified and dispersed neatly in water, and no emulsified phase was separated. In contrast, in Comparative Examples 1 and 2 obtained using a double nozzle containing no surfactant, the oily components did not emulsify and disperse neatly in water, and the oil floated considerably. Yes, the milkiness was low, and the evaluation was x.

Test Example 2 5 g of the content liquid of the capsule particles obtained in Example 2 was taken out, transferred to a test tube, and allowed to stand in an atmosphere of 25 ° C. and 60% humidity for 6 hours, and then visually observed for its properties. Was. As a result, in the content liquid in the test tube, the surfactant component was uniformly dispersed in the oil component.

[0057]

According to the present invention, it is possible to provide capsule particles having a seamless film and containing a surfactant component and an oily component. The capsule particles are also preferable in appearance, have a sharp particle size distribution, have a uniform film thickness, and have excellent solubility. Also, emulsifying dispersibility of the content liquid,
Alternatively, since the surfactant is excellent in dispersibility and solubility in oily components, it can be effectively used in the fields of bath products, cleaning products, and the like. Particularly, when used as a bath agent, an oily component having an effect on the skin can be used as a surfactant. Is useful because it can be emulsified and dispersed.

[Brief description of the drawings]

FIG. 1 is a cross-sectional view schematically showing one example of a nozzle portion of a manufacturing apparatus used in a manufacturing method according to the present invention.

FIG. 2 is a schematic view of an emulsifiability test apparatus according to the present invention.

[Explanation of symbols]

 1 Inner Nozzle 2 Intermediate Nozzle 3 Outer Nozzle 4 Outer Nozzle Inlet 5 Intermediate Nozzle Inlet 6 Inner Nozzle Inlet 7 3 L Beaker 8 Motor 9 Anchor Wing D Wing Diameter (5 cm) H Wing Height (5 cm) m Wing Width (1cm) h Distance from upper surface of wing to water surface (1cm)

Continuation of the front page (56) References JP-A-54-35210 (JP, A) JP-A-51-8178 (JP, A) JP-A-53-72814 (JP, A) (58) Fields investigated (Int) .Cl. ⁶ , DB name) C11D 17/08 A23L 1/00 A61K 9/48 B01J 13/14

Claims (9)

(57) [Claims] 1. Capsule particles comprising an inner layer and an outer layer having a film-forming body, wherein the inner layer has an anionic surfactant.
Agents, cationic surfactants and HLB 9-18
At least one field selected from the group consisting of ionic surfactants
A surfactant component and an oil component are contained, and the emulsifying property of the content liquid of the capsule particles is such that 0.5 g of the content liquid is poured into 2.5 liters of 40 ° C. water and stirred under the following conditions.
A seamless capsule particle containing a surfactant, wherein the oil component in the inner layer is emulsified and dispersed and is not substantially separated from water at a temperature of ° C. Stirring conditions; Container: 3 liter beaker (beaker inner diameter 14 cm,
Stirring blade: Anchor blade (wing diameter: 5 cm, blade height: 5 cm, blade width: 1 cm) Blade position: Upper surface of blade is lower than 1 cm below water surface Rotation speed of blade: 150 rpm Stirring time: 30 seconds 2. Capsule particles comprising a single inner layer and an outer layer having a film-forming body, wherein the inner layer is an anionic layer.
Surfactants, cationic surfactants and HLB 9-18
At least one member selected from the group consisting of nonionic surfactants
Surfactant- containing seamless capsule particles comprising the above surfactant component and an oily component, wherein the surfactant component is substantially uniformly dispersed or dissolved in the oily component. 3. The surfactant-containing seamless capsule particles according to claim 1, wherein the coating ratio, which is the weight ratio of the coating to the weight of the capsule particles, is 5 to 60% by weight. 4. An average particle diameter of the capsule particles is 0.2 mm.
The surfactant-containing seamless capsule particles according to claim 1 or 2, wherein the diameter is from 2 to 2 cm. 5. The capsule particle having an inner layer having a concentric layer structure of two or more layers and having a film-forming body on the outer side thereof, wherein an anionic surfactant, a cationic surfactant and
And a group consisting of HLB 9-18 nonionic surfactants
Contains one or more selected surfactant components, and
A surfactant-containing seamless capsule particle having any one of the following structures (A) to (D). (A) at least one layer in the inner layer is composed of an aqueous dispersion containing an oil component and a surfactant component; and (B) at least one layer in the inner layer is formed of an oil component and a surfactant. (C) at least one layer in the inner layer comprises an oil component and a surfactant component; and (D) at least one layer in the inner layer. The above layers consist of a surfactant component. 6. The emulsifying property of the content liquid of the capsule particles is such that 0.5 g of the content liquid is poured into 2.5 liters of water at 40 ° C., and stirred at 40 ° C. under the conditions described in claim 1; The surfactant-containing seamless capsule particles according to claim 2 or 5, wherein the oily component in the inner layer is in a state of being emulsified and dispersed and not substantially separated from water. 7. The non-ionic surfactant is one or more selected from the group consisting of sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, and polyoxyethylene sorbitol fatty acid esters. Item 6. The surfactant-containing seamless capsule particles according to item 1, 2 or 5 . 8. The film forming body according to claim 1, wherein the main component is at least one member selected from the group consisting of natural, semi-synthetic and synthetic hydrophilic polymers. 5. The surfactant-containing seamless capsule particles according to 5. 9. The seamless capsule particle containing a surfactant according to claim 1, which is used as a bathing agent.