JP2533527B2 - Automatic analyzer - Google Patents

Description

TECHNICAL FIELD The present invention relates to an automatic analyzer, and more particularly to an automatic analyzer suitable for measuring colorimetric items and electrolyte items having different measurement times.

[Conventional technology]

With the development of clinical biochemical tests, it has become desirable to be able to simultaneously measure colorimetric items and electrolyte items. Conventionally, a method of collectively outputting one sample in the sampling order has been adopted. That is, the measurement result of the sample is always output at regular time intervals according to the output timing of the colorimetric item having a long measurement time.

[Problems to be solved by the invention]

The above-mentioned conventional technique is to output the measurement result at the output timing of the colorimetric measurement result regardless of whether there is a measurement request for the colorimetric item. Therefore, when only the electrolyte item was requested, the output of the electrolyte item took the same amount of time as the colorimetric item, although the measurement time was shorter than that of the colorimetric item.

The electrolyte item is a very urgent test item that may be measured even in a severe patient who has fallen into a coma, for example, and it is necessary to quickly output the measurement result. Therefore, there is a problem in that it is impossible to promptly provide the user with a highly urgent test result.

An object of the present invention is to solve such conventional problems and to provide an automatic analyzer capable of outputting a measurement result quickly at a timing according to a user's need.

[Means for solving problems]

The purpose is to provide two tables, a priority output table for storing the calculation results of only electrolyte items as measurement request items and a general output table for storing the calculation results of other items, and the two tables. This is achieved by providing a function of managing the output timing of the calculation result stored in the table.

[Action]

By storing the calculation results of the electrolyte items that must be output earlier in the priority output table, and by outputting the data of the priority table first when outputting, the electrolyte items are irrespective of the measurement time of the colorimetric item. It will be possible to output quickly.

〔Example〕

An embodiment of the present invention will be described in detail below with reference to the drawings. FIG. 1 shows the configuration of an embodiment of the present invention. The reaction table 1 has a reaction container 2 also serving as a plurality of measuring cells on its circumference, and can freely rotate around a rotation shaft 3. The sample table 4 has a plurality of sample containers 5 on its circumference, and can freely rotate around a rotation shaft 6. Sample suction tube 7
Is connected to the dispensing mechanism 59, and the suction and discharge operation of the dispensing mechanism 59 allows the sample to be sucked and discharged. This operation is
It is performed in the order of electrolyte. Further, the sample suction / exhaust pipe 7 is rotated around the rotation shaft 8 by the rotation operation of the dispensing mechanism 59, and the reaction table 1
A sample suction / discharge pipe cleaning mechanism 9 is installed below the rotation passage of the sample suction / discharge pipe 7 because it can freely rotate between the sample table 4 and the electrolyte measuring device 60.

Dispensing of the reagent is performed by the reagent dispenser 10, the flow path 11, the flow path 12, the flow path 13,
This is performed by a reagent dispensing mechanism including a flow path switching device 14 and a reagent dispensing device 15.

The stirring rod 20 is connected to the stirring mechanism 21, rotates by the rotation operation of the stirring mechanism 21, and moves up and down by the vertical movement. Spectroscope
Reference numeral 30 is provided so as to face the light source lamp 31, and the reaction container 2 passes through the light flux 32 when the reaction table 1 rotates, and the light absorption measurement is performed at that time.

The details of the electrolyte measuring device 60 are as shown in FIG. First, the internal standard solution syringe 64 starts to operate, and the internal standard solution 65 is discharged to the dilution tank 68. Next, the shipping syringe 69 operates to draw the internal standard solution in the diluting tank 68 into the electrolyte thermostat 70. The internal standard solution is the ion selective electrodes 61, 62,
Stop inside 63 and measure the electromotive force of the internal standard solution. The measurement result is stored in the storage device 50 shown in FIG.

The principle of analyzing colorimetric items will be described below with reference to FIG. When the sample container 5 containing the sample to be measured, eg, serum, reaches the sampling position 41, the tip of the sample suction / discharge pipe 7 is immersed in the sample container 5 to suck a fixed amount of serum, and the sample suction / discharge pipe 7
Hold in. After that, the sample intake / exhaust pipe 7 is connected to the reaction table
To the discharge position 51, and the serum held in the reaction container 2 being transferred to the discharge position 51 is discharged.

After the end of the discharge, the sample suction / discharge pipe cleaning mechanism 9 is moved to above and the inside and outside of the sample suction / discharge pipe 7 are washed with water. When the above sampling operation is completed, the reaction container 2 reaches the reagent dispensing position 52 through the transfer process. Therefore, when the flow passage 11 and the flow passage 12 are connected by the flow passage switcher 14, the reagent in the reagent container 16 is discharged from the reagent discharge pipe 10 into the reaction container 2 by the reagent dispenser 15. By the above operation, the sample to be measured is mixed with the reagent to start the reaction. After that, the reaction vessel 2 that has reached the stirring position 53 through the transfer process again is stirred by the stirring rod 20 and the reaction is continued. After that, the reaction container 2 reaches the cleaning position 54 through a transfer process. During this time, that is, during the transfer process from the reagent discharge position 52 to the cleaning position 54, the reaction container 2 keeps the luminous flux.
A light absorption measurement is made in the spectroscope 30 after each passage through 32.

The reaction container 2 that has reached the cleaning position 54 is a reaction container suction / discharge pipe.
The liquid inside is sucked and discharged by 42 and washed by the washing mechanism 58 through the washing positions 55, 56, 57, and then used as the reaction container 2 again from the discharging position 51 after the transfer process.

Next, the measurement principle of the electrolyte item will be described with reference to FIGS. The sample 22 set on the sample table 4 is moved to the center of the dilution tank 68 by the sample suction / discharge pipe 7, and the sample 22 is discharged into the dilution tank 68. At the same time, dilute syringe 66
Operates to discharge the diluting liquid 67 into the diluting tank 68. The sample 22 mixed with the diluting liquid 67 is sucked into the electrolyte thermostat 70 by the shipper syringe 69, and the electromotive force of the electrolyte is measured. Then, it is stored in the storage device 50. Further, the concentration of the electrolyte is calculated from the difference with the electromotive force of the internal standard solution 65 stored in the storage device 50. The mixed liquid of the measured sample and the diluting liquid is discharged to the waste liquid tank 71 by the shipping syringe 69. All of these operations are controlled by the controller 40.

As mentioned above, there is a difference in the time from the start of analysis to the confirmation of the analysis result because the analytical method is different between the colorimetric item and the electrolyte item. About 10 minutes for the colorimetric item and about 10 minutes for the electrolyte item. 1 minute. For this reason, in the past, even though the electrolyte item was previously determined, it was not output until the colorimetric item was determined.

The difference in output timing between the conventional method and the present invention will be described with reference to FIG. When the analysis starts, N ₁ · E ₁
・ Sampling is performed in the order of N ₂ and N ₃ .

General sample N ₃ and urgent sample requested to measure only electrolyte items
The data of E ₁ is determined 1 minute after the end of sampling, but conventionally, the output to the outside was performed 10 minutes after the end of sampling.

On the other hand, in the present invention, the output to the outside is performed immediately after the electrolyte data is determined.

In one embodiment to which the present invention is applied, only in the case of an urgent sample for which only the electrolyte item is requested to be measured, it is output to the outside immediately after the electrolyte data is determined, and when only the electrolyte item is requested in the general sample, it is the same as the conventional method. It is output at the timing.

Next, the output process to the printer when the measurement item in the general or urgent sample is requested to measure only the electrolyte item
A description will be given according to the flow charts of FIGS.

FIG. 4 shows a process of storing the calculation result in the output table. First, it is determined whether only the electrolyte item is included. If only the electrolyte item is included, the calculation result is stored 102 in the priority output table. When the analysis items are only colorimetric or colorimetric and electrolyte, the calculation result storage 103 is performed in the general output table.

FIG. 6 shows a process of outputting the data stored in the output table to the printer. First, it is determined whether the output timing is reached 110. If the output timing is reached, the priority output table reference 111 is performed. Next, it is determined 112 whether priority output data is stored, and if it is stored, output 113 to the printer is performed, and then priority output data clear 114 is executed.

On the other hand, if there is no priority output data, it is judged 119 whether the data pointed by the pointer (information indicating the output order of the data in the output table) has been output, and if it has been output, the pointer is updated 120. If the data pointed to by the pointer has not been output, the general output table is referenced 115. Next, determine if the data is stored 11
6 is performed, and if there is data here, output 117 to the printer is performed. Then, the pointer is updated 118.

The output to the printer when only the electrolyte item is requested as the measurement request item has been described above, but this method is suitable for an emergency device that needs to output the electrolyte item particularly quickly.

Next, the output method to the printer when only the electrolyte item is requested to be measured in the urgent sample (sample that is interrupted and analyzed during general analysis) will be described. This method is suitable for routine inspection equipment.

FIG. 5 shows a process of storing the calculation result in the output table. First, it is determined 105 whether the analysis sample is an urgent sample, and if it is a general sample, the calculation result is stored 108 in the general output table. Then, in the case of an urgent sample, it is determined whether the analysis item is only the electrolyte item, and when it is only the electrolyte item, the calculation result is stored 107 in the priority output table. When the analysis items are only colorimetric or colorimetric and electrolyte, the storage 108 in the general output table is performed. Further, the output method to the printer is the same as the output method when the measurement request item described in FIG. 6 is requested only for the electrolyte item, but the priority output is the urgent sample and only the electrolyte item is requested. This is the case.

〔The invention's effect〕

According to the present invention, in the analyzer capable of analyzing the colorimetric item and the electrolyte item, if only the electrolyte item is requested to be analyzed for the sample for which the operation result is obtained, the operation result data is used for priority output. Since the table is immediately output to the printer, the analysis result can be obtained in a shorter time than the output possible time of the density calculation result of the colorimetric item. Therefore, in the case of an urgent sample for which many tests are requested only for electrolyte items, the time from the start of analysis to the output of the analysis result to a printer is shortened.

[Brief description of drawings]

FIG. 1 is a block diagram of an automatic analyzer which is an embodiment of the present invention,
FIG. 2 is a block diagram of the electrolyte measuring device, FIG. 3 is an output timing diagram of the conventional and the present invention, FIGS. 4 and 5 are diagrams showing a process of storing the calculation result in an output table, and FIG. It is a figure showing the processing which outputs a calculation result to a printer from an output table. 2 ... Reaction vessel, 15 ... Sample dispenser, 21 ... Stirring mechanism,
30 …… Spectroscope, 40 …… Control device, 50 …… Storage device, 58…
… Cleaning mechanism, 69 …… Dispensing mechanism, 64 …… Internal standard solution syringe, 66 …… Diluent syringe, 69 …… Shipper syringe, 80 …… Printer.

Claims (1)

(57) [Claims] 1. A spectroscope for optically detecting a characteristic of a specimen,
An electrolyte measuring device having an ion selective electrode for measuring an electrolyte item, and a concentration calculation result of a colorimetric item calculated based on the output signal of the spectroscope and an electrolyte item calculated based on the output signal of the electrolyte measuring device. In an automatic analyzer equipped with a storage device for storing concentration calculation results, a general output table storing calculation result data of colorimetric items and a priority output table storing calculation result data of only electrolyte items , A request status determination means for determining whether or not only the electrolyte item is requested for the sample obtained as a result of calculation is provided, and prior to the check of the data storage state in the general output table, the priority output table Check the data storage status and configure it to output the data to the printer when the data is stored in the above priority output table. Automatic analyzer, characterized in that.